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Fengping Zhang,정명락,김문영 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.4
This paper presents extended deflection theories of multi-span continuous suspension bridges and their FE formulations using the energy method. The proposed deflection theories take into account effects of hanger extensibility, free sliding of main cables at the saddle, and floating girders. Suspension bridge elements consisting of main girder, main cable, and tower elements are then introduced and simplified FE formulations are rigorously proposed to solve the extended deflection theories. In order to demonstrate the validity and accuracy of the presented formulation, three/four-span suspension bridge models having regular and floating support conditions of the main girder are analyzed using the simplified FEMs, and the analysis results are compared with those by the unstrained length method, which is a sophisticated FEM. Finally, three virtual earth-anchored suspension bridge models are analyzed to explore the effects of hanger extensibility.
Fengping Ye,Qili Mi,Ning Zhang,Xuemei Li,Jing Yu,Zhongping Gao,Ying Zheng,Quanshui Fan,Jie Wang,Jinglin Wang 대한화학회 2016 Bulletin of the Korean Chemical Society Vol.37 No.5
Chemical modifications of the nucleotides can improve the stability of aptamers against enzyme degradation in serum, but it is not clear whether these methods are effective in snake venom. In this study, a DNA aptamer, βB-1, which specifically recognize β-bungarotoxin and Bungarus multicinctus venom was chosen, and the key binding sequence of the aptamer was determined. Based on the secondary structure of the truncated aptamer, locked nucleic acids and 2′-O-methyl nucleotides were applied to modify the stem and loop sequences, respectively. In addition, a 3′-3′-thymidine cap was also adopted to block the 3′ end. It was shown that these chemical modifications can all enhance the stability of the aptamer in snake venom. Simultaneously, modified aptamer with the above modifications in one sequence exhibited a significantly elevated biostability, with the half-life improved from several minutes to 210 min while maintaining its binding affinity to the target.
( Wei Fengping ),( Choi Myeongcheol ),( Shang Xianfa ),김한얼 ( Kim Hannearl ) 한중사회과학학회 2021 한중사회과학연구 Vol.19 No.1
China has a long history and has produced a large number of time-honored enterprises. Embodying a distinctive traditional Chinese cultural heritage, they have contributed to the economic development of the country and have been highly respected in the society. Analyzing those companies with modern strategy frameworks could shed new lights on the key success factors and propose new ideas to further improve their performance. This paper investigates the Chinese liquor industry and, in particular, the Qinghai Mutual Barley Wine Company. While the company has a long history and a potential for growth, it needs to be more strategic to take advantage of the opportunities. To assess the strategic positioning of the company, we have conducted SWOT and Porter’s competitive strategy analysis, which identified poor management, insufficient publicity, a large number of counterfeit and inferior products, low brand reputation as a source of problem.
Huang, Fengping,Wang, Shuai,Zhang, Shuang,Fan, Yingge,Li, Chunxue,Wang, Chuang,Liu, Chun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.8
The praseodymium-doped $TiO_2$ photocatalyst samples, which could degrade methyl orange under UV irradiation, were prepared by sol-microwave method for improving the photocatalytic activity of $TiO_2$. The resulting materials were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Raman spectra, Fourier transform infrared spectra (FTIR) and Ultraviolet-visible diffuse reflectance spectra (UV-vis DRS). It was found Pr doping retarded the growth of crystalline size and the phase transformation from anatase to rutile, and narrowed the band gap energy. Praseodymium doping brought about remarkable improvement in the photoactivity. The optimal dopant amount of Pr was 2% by molar of cement and the calcination temperature was $500^{\circ}C$ for the best photocatalytic activity. The improvement of photocatalytic activity was ascribed to the occurrence of lattice distortion and the effective containment of the recombination of the electron-hole by $Pr^{3+}$.
Tao Li,Fengping An,Hui Teng,Qun Huang,Feng Zeng,Hong-bo Song 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
Resistant starches (RS) were prepared from purple yam by dual autoclaving-retrogradation (DAS), and pullulanase debranching treatment (PDS). DAS and PDS were then hydrolyzed by a-amylase and amyloglucosidase to obtain DAS.H and PDS.H. Differences in structural characteristics and in vitro digestibility among the four samples were investigated. The results showed that granules of RS had a rough surface and irregular shape. DAS had the lowest amylose content (29.52%), whereas PDS.H had the highest amylose content (41.96%). The order of crystallinity of the RS was: PDS.H (31.23%)[DAS.H (30.16%)[PDS (21.23%)[DAS (15.30%). Analysis by in vitro digestibility indicated a decreased hydrolysis index and glycemic index due to lower swelling power and water-binding capacity, and a well-ordered double helix structure and more crystallization in PDS.H than in the other RS samples. These results suggest that pullulanase debranching combined with a-amylase and amyloglucosidase hydrolysis may produce better RS with improved crystalline structure and higher digestion resistibility.
Ying Hou,Fengping Wang,Zhilei Tan,Jiandong Cui,Shiru Jia 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.3
ε-Poly-L-lysine (ε-PL) is a natural antimicrobial cationic peptide. Antimicrobial activity of ε-PL is closely related to its molecular weight (Mw). However, the antimicrobial mechanisms of ε-PL with different Mws are still vague. In this study, Saccharomyces cerevisiae was used as the model system to analyze the mechanism from these three aspects: cell wall, cell membrane, and metabolism. The results showed that high-Mw ε-PL (1-3 kDa and >3 kDa) and commercial ε-PL product caused cell wall lesions, and significantly improved cell membrane permeability compared to low-Mw ε-PL (<1 kDa), resulting in leaking of the protoplasm through the pores and cell death. Furthermore, metabolomics analysis showed that high-Mw ε-PL (1-3 kDa and >3 kDa) and product displayed higher inhibition effect on the glycolysis pathway and tricarboxylic cycle than that of low-Mw ε-PL (<1 kDa).
A New Cytotoxic Phenazine Derivative from a Deep Sea Bacterium Bacillus sp.
Dehai Li,Fengping Wang,Xiang Xiao,Xiang Zeng,Qian-Qun Gu,Weiming Zhu 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.5
A novel phenazine derivative (1) together with six known compounds (2-7) were isolated by bioassay-guided fractionation from the culture broth of a bacterium, Bacillus sp., collected from a Pacific deep sea sediment sample (depth 5059 m). The structures of these compounds were determined using spectroscopic methods. Their cytotoxic effects on P388 and K562 cell lines were preliminarily examined using the sulforhodamine-B (SRB) assay.
( Yutang Ren ),( Xiaowei Tang ),( Fengping Chen ),( Zhiliang Deng ),( Jianuan Wu ),( Soma Nei ),( Bo Jiang ),( Wei Gong ) 대한소화기기능성질환·운동학회 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.1
Background/Aims The motility change after peroral endoscopic myotomy (POEM) in achalasia is currently focused on lower esophageal sphincter (LES). This study aims to investigate the correlation of motility response between distal and proximal esophagus after POEM. Methods A total of 32 achalasia patients who received POEM and high-resolution manometry (HRM) were included for analysis. Eckardt score was used to assess symptom improvement. HRM was applied for studying motility. Main parameters analyzed were (1) LES: resting pressure (restP), 4-second integrated relaxation pressure; (2) esophageal body (EB): contractile integral of distal segment with myotomy (CI-DM) and proximal segment without myotomy (CI-PNM); and (3) upper esophageal sphincter (UES): relaxation pressure (UES-RP). Results There were 6 type I, 17 type II, and 9 type III achalasia patients included for analysis. (1) Eckardt score, LES tone, CI-DM, CI-PNM and UES-RP were reduced remarkably after POEM (P < 0.001). (2) no significant correlation was noted between LES tone and contractile intergral of EB. (3) a positive linear correlation of CI-DM and CI-PNM changes was detected (P < 0.001). (4) the change of UES-RP was positively correlated with the change of contractile integral of EB (P < 0.001). Conclusions Myotomy of the distal esophagus would attenuate proximal EB contraction and assist UES relaxation in achalasia patients after POEM. (J Neurogastroenterol Motil 2016;22:78-85)
Li, Tao,An, Fengping,Teng, Hui,Huang, Qun,Zeng, Feng,Song, Hongbo 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.1
Resistant starches (RS) were prepared from purple yam by dual autoclaving-retrogradation (DAS), and pullulanase debranching treatment (PDS). DAS and PDS were then hydrolyzed by ${\alpha}-amylase$ and amyloglucosidase to obtain DAS.H and PDS.H. Differences in structural characteristics and in vitro digestibility among the four samples were investigated. The results showed that granules of RS had a rough surface and irregular shape. DAS had the lowest amylose content (29.52%), whereas PDS.H had the highest amylose content (41.96%). The order of crystallinity of the RS was: PDS.H (31.23%) > DAS.H (30.16%) > PDS (21.23%) > DAS (15.30%). Analysis by in vitro digestibility indicated a decreased hydrolysis index and glycemic index due to lower swelling power and water-binding capacity, and a well-ordered double helix structure and more crystallization in PDS.H than in the other RS samples. These results suggest that pullulanase debranching combined with ${\alpha}-amylase$ and amyloglucosidase hydrolysis may produce better RS with improved crystalline structure and higher digestion resistibility.
Pavement Crack Detection by Ridge Detection on Fractional Calculus and Dual-thresholds
Song Hongxun,Wang Weixing,Wang Fengping,Wu Linchun,Wang Zhiwei 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.4
In this paper, a new road surface crack detection algorithm is proposed; it is based on the ridge edge detection on fractional calculus and the dual-thresholds on a binary image. First, the multi-scale reduction of image data is used to shrink an original image to eliminate noise, which can not only smooth an image but also enhance cracks. Then, the main cracks are extracted by using the ridge edge detection on fractional calculus in a grey scale image. Subsequently, the resulted binary image is further processed by applying both short and long line thresholds to eliminate short curves and noise for getting rough crack segments. Finally the gaps in cracks are connected with a curve connection function which is an artificial intelligence routine. The experiments show that the algorithm for pavement crack images has the good performance of noise immunity, accurate positioning, and high accuracy. It can accurately locate and detect small and thin cracks that are difficult to identify by other traditional algorithms.