Effect of Grinding Parameters on Industrial Robot Grinding of CFRP and Defect Formation Mechanism

Fangyuan Wang,Shanyong Xuan,Zongyu Chang,Kai Jin,Yulong Gao,Hao Wang,Qiye Song 한국정밀공학회 2024 International Journal of Precision Engineering and Vol.11 No.2

The use of industrial robots for grinding CFRP is a green processing method. This method not only allows in-situ repair to reduce unnecessary waste of resources, but also produces no excessive contaminants. The effect of various process parameters, including grinding directions, the mesh size of grinding heads and rotating speed, on the grinding quality of Carbon Fiber Reinforced Polymers (CFRP) using industrial robots was investigated. The mechanism of grinding defects was also studied. According to the experimental results, the CFRP grinding process is mainly controlled by the rotating speed, number of grinding heads, and grinding direction. In particular, high-speed grinding helps to improve the surface quality of CFRP. In turn, the use of diamond grinding heads with too small or too large particles may reduce surface quality. Grinding quality changes with the grinding direction. In the grinding direction between 0° and 90°, the surface roughness increases with the angle (but drops at 60°), and The same trend is observed in the grinding direction between 90° and 150°, whereby the surface roughness increases with the angle (but drops at 120°). The surface quality of CFRP is thereby improved after grinding in the direction of 0°, 60°, 120° and 180°. Furthermore, the fiber pull-out occurs, when the feed direction and fiber orientation are aligned. Finally, the low-frequency vibration easily causes fiber pull-out defects.

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

Wang, Shuaifei,Li, Fangyuan,Qiao, Ruirui,Hu, Xi,Liao, Hongwei,Chen, Lumin,Wu, Jiahe,Wu, Haibin,Zhao, Meng,Liu, Jianan,Chen, Rui,Ma, Xibo,Kim, Dokyoon,Sun, Jihong,Davis, Thomas P.,Chen, Chunying,Tian, American Chemical Society 2018 ACS NANO Vol.12 No.12

<P>Ferroptosis, an iron-based cell-death pathway, has recently attracted great attention owing to its effectiveness in killing cancer cells. Previous investigations focused on the development of iron-based nanomaterials to induce ferroptosis in cancer cells by the up-regulation of reactive oxygen species (ROS) generated by the well-known Fenton reaction. Herein, we report a ferroptosis-inducing agent based on arginine-rich manganese silicate nanobubbles (AMSNs) that possess highly efficient glutathione (GSH) depletion ability and thereby induce ferroptosis by the inactivation of glutathione-dependent peroxidases 4 (GPX4). The AMSNs were synthesized <I>via</I> a one-pot reaction with arginine (Arg) as the surface ligand for tumor homing. Subsequently, a significant tumor suppression effect can be achieved by GSH depletion-induced ferroptosis. Moreover, the degradation of AMSNs during the GSH depletion contributed to <I>T</I><SUB>1</SUB>-weighted magnetic resonance imaging (MRI) enhancement as well as on-demand chemotherapeutic drug release for synergistic cancer therapy. We anticipate that the GSH-depletion-induced ferroptosis strategy by using manganese-based nanomaterials would provide insights in designing nanomedicines for tumor-targeted theranostics.</P> [FIG OMISSION]</BR>

Tuning properties of NC3H quantum dot by adsorption of ammonia and carbon dioxide

Ambreen kalsoom,Fangyuan Wang 한국물리학회 2015 Current Applied Physics Vol.15 No.11

Transport properties of NC3H quantum dot by adsorption of ammonia and carbon dioxide are investigated with an ab initio method combined with a non-equilibrium Green function method. The effects of different configurations of ammonia, size of NC3H surface and position where ammonia and carbon dioxide had been adsorbed onto NC3H quantum dot on transport properties are revealed. In comparison with NC3H quantum dot device, results show that the adsorption of ammonia molecule on NC3H quantum dot in one configuration enhances the conductance of device, while adsorption in another configuration reduces the conductance. The size of NC3H significantly altered the transport properties in both NC3HeNH3 and NC3HeCO2 system. The position of adsorption of ammonia displays obvious change on transport properties while the effects of position of carbon dioxide on transport properties are negligible.

Preparation of new visible-light driven nanocomposite photocatalysts, X/NaTaO3/Er3+:YAlO3 (X = Ag, Au and Pt), for photocatalytic conversion of Cr(VI)

Bowen Li,Yidi Wang,Fangyuan Tian,Guanshu Li,Zhaohong Zhang,Jun Wang,Youtao Song 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.54 No.-

In order to expand the light response range of wide band-gap semiconductor photocatalyst (NaTaO3) for effective photocatalytic conversion of Cr(VI), an up-conversion luminescence agent (Er3+:YAlO3) is combined with NaTaO3 and a visible-light driven photocatalyst, NaTaO3/Er3+:YAlO3, is prepared. Moreover, several conduction band co-catalysts (Ag, Au and Pt) are deposited the surface of NaTaO3/Er3+: YAlO3, respectively, to facilitate the transfer rate of photo-generated electrons. X-ray diffractometer (XRD), energy dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM) analyses are employed to confirm the morphology, microstructure and composition of the prepared photocatalysts. In addition, UV–vis diffuse reflectance spectra are determined to explore the visible-light absorption properties of Er3+:YAlO3, NaTaO3, NaTaO3/Er3+:YAlO3 and X/NaTaO3/Er3+:YAlO3 (X = Ag, Au and Pt). Photoluminescence (PL) spectra are used to estimate the recombination rate of electron–hole pairs. The effects of irradiation time, photosource kind, solution acidity and used times on the photocatalytic capabilities of NaTaO3/Er3+:YAlO3 and X/NaTaO3/Er3+:YAlO3 (X = Ag, Au and Pt) are investigated in detail. The results show that the uses of up-conversion luminescence agent (Er3+:YAlO3) and co-catalysts (Ag, Au and Pt) can promote NaTaO3 to utilize visible-light to carry out the photocatalytic conversion of Cr(VI). Particularly, the prepared Au/NaTaO3/Er3+:YAlO3 nanocomposite with 1.0 wt% Au and 0.3:1.0 molar ratio of Er3+:YAlO3 and NaTaO3 shows the highest photocatalytic activity in conversion of Cr(VI).

Untargeted metabolite profiling of serum in rats exposed to pyrraline

Chuanqin Hu,Jiahui Wang,Fangyuan Qi,Yingli Liu,Fen Zhao,Jing Wang,Baoguo Sun 한국식품과학회 2023 Food Science and Biotechnology Vol.32 No.11

Pyrraline, one of advanced glycation end-products, is formed in advanced Maillard reactions. It was reported that the presence of pyrraline was tested to be associated with nephropathy and diabetes. Pyrraline might result in potential health risks because many modern diets are heat processed. In the study, an integrated metabolomics by ultra-high-performance liquid chromatography with mass spectrometry was used to evaluate the effects of pyrraline on metabolism in rats. Thirty-two metabolites were identified as differential metabolites. Linolenic acid metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, arachidonic acid metabolism, tyrosine metabolism and glycerophospholipid metabolism were the main perturbed networks in this pathological process. Differential metabolites and metabolic pathways we found give new insights into studying the toxic molecular mechanisms of pyrraline.

Study on surface physical and chemical mechanism of nanobubble enhanced flotation of fine graphite

Tang Chongliang,Ma Fangyuan,Wu Tingyu,Zhang Di,Wang Ye,Zhao Tonglin,Fan Zhaolin,Liu Xinyue 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.122 No.-

It has been concluded in a recently published investigation that the nanobubble flotation process significantlyreduces the number of fine flake graphite flotation stages and improves the flotation performance. The present study was conducted to explore the mechanisms of surface nanobubbles enhancing flake graphiteflotation by investigating effects of nanobubbles on surface properties of graphite and interactionsbetween particles and bubbles by use of contact angle analyzer, zeta potential analyzer, FourierTransform Infrared Spectroscopy (FTIR), and X-ray Photoelectron Spectroscopy (XPS). The study resultsshow that nanobubbles can improve the surface properties of graphite and enhance the adsorption effectof collector, which increased the contact angle of the graphite surface by 11.93 compared with conventionalflotation. Infrared spectroscopy and potential analysis showed that the nanobubbles could enhancethe hydrophobic attraction and reduce the electrostatic repulsion between the collector and the graphitesurface, which was beneficial to enhance the hydrophobic surface of the graphite and enhance theagglomeration of fine graphite particles. XPS analysis showed that the nanobubbles covered polar hydrophilicgroups (such as CAO, C@O, COOH) on the graphite surface, which enhanced the adsorption of collectorto improve the hydrophobicity of graphite surface.

DC Voltage Balancing and Current Sharing Control of Parallel Multiple Modules Static Var Generator Based on CPS-SPWM

Cai, Wei,Huang, Yanyan,Fangyuan, Zhou,Qiu, Wenjun,Wang, Caixiao,Wu, Qiang,Erlei, Shi,Wen, Tao The Korean Institute of Electrical Engineers 2013 The Journal of International Council on Electrical Vol.3 No.1

For extending the power and improving the performance of SVG, a topology with several parallel plugging convertor modules is obtained, which has no common DC bus. In respect that the parameter difference among converters, reactive power of total output sharing has to be resolved. In this article, mathematics model with DQ analytic transformation is analyzed. Based on double close-loop decoupling control, and direct current control, a reactive power balance current sharing method is proposed. By using CPS-SPWM, the current harmonic of SVG is reduced, which is indicated by simulation result. Further, in order to apply the method to project application, a 2Mvar platform with a double FPGA-DSP controller broad is carried out. The simulation and practical performance of SVG are given. The validity and feasibility of the method is demonstrated by the results.

Modeling of dynamic recrystallization in white layer in dry hard cutting by finite element—cellular automaton method

Duan Chunzheng,Zhang Fangyuan,Qin Siwei,Sun Wei,Wang Minjie 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.9

White layer formed in hard cutting process has great influence on surface quality of the workpiece, simulation of the white layer has great significance. Dynamic recrystallization critical temperature model is derived to calculate the critical temperature of the dynamic recrystallization in the white layer. A finite element model was developed to simulate the hard cutting process based on the JohnsonCook constitutive equation. The dynamic recrystallization critical temperature was derived based on the true stress-strain curves obtained by the split Hopkinson pressure bar experiments. The cellular automaton model which aims to simulate the white layer grains formed by the dynamic recrystallization process in hard cutting is established. The temperature and strain data extracted from the finite element model are used in the cellular automaton model. The contrast between the simulation and experimental results demonstrates that the cellular automaton model can simulate the dynamic recrystallization process in the white layer accurately. The dynamic recrystallization processes in the white layer under different cutting speed and flank wear are simulated based on the finite element - cellular automaton model. The results show that the dynamic recrystallization grain size of the white layer decreases with the increase in cutting speed and tool wear.

The stacked over-expression of FPS, CYP71AV1 and CPR genes leads to the increase of artemisinin level in Artemisia annua L.

Yunfei Chen,Qian Shen,Yueyue Wang,Tao Wang,Shaoyan Wu,Ling Zhang,Xu Lu,Fangyuan Zhang,Weimin Jiang,Bo Qiu,Erdi Gao,Xiaofen Sun,Kexuan Tang 한국식물생명공학회 2013 Plant biotechnology reports Vol.7 No.3

Artemisinin is an endoperoxide sesquiterpenelactone isolated from the aerial parts of Artemisia annua L.,and is presently the most potent anti-malarial drug. Owingto the low yield of artemisinin from A. annua as well as thewidespread application of artemisinin-based combinationtherapy recommended by the World Health Organization,the global demand for artemisinin is substantially increasingand is therefore rendering artemisinin in short supply. An economical way to increase artemisinin production is toincrease the content of artemisinin in A. annua. In thisstudy, three key genes in the artemisinin biosynthesispathway, encoding farnesyl diphosphate synthase, amorpha-4, 11-diene C-12 oxidase and its redox partner cytochromeP450 reductase, were over-expressed in A. annuathrough Agrobacterium-mediated transformation. Thetransgenic lines were confirmed by Southern blotting andthe over-expressions of the genes were demonstrated byreal-time PCR assays. The HPLC analysis showed that theartemisinin contents in transgenic lines were increasedsignificantly, with the highest one found to be 3.6-foldhigher (2.9 mg/g FW) than that of the control. Theseresults demonstrate that multigene engineering is aneffective way to enhance artemisinin content in A. annua.

Highly Sensitive Diagnosis of Small Hepatocellular Carcinoma Using pH-Responsive Iron Oxide Nanocluster Assemblies

Lu, Jingxiong,Sun, Jihong,Li, Fangyuan,Wang, Jin,Liu, Jianan,Kim, Dokyoon,Fan, Chunhai,Hyeon, Taeghwan,Ling, Daishun American Chemical Society 2018 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.140 No.32

<P>Iron oxide nanoparticle (IONP)-based magnetic resonance imaging (MRI) contrast agents have been widely used for the diagnosis of hepatic lesions. However, current IONP-based liver-specific MRI contrast agents rely on single-phase contrast enhancement of the normal liver, which is not sensitive enough to detect early stage small hepatocellular carcinomas (HCCs). We herein report i-motif DNA-assisted pH-responsive iron oxide nanocluster assemblies (termed RIAs), which provide an inverse contrast enhancemt effect to improve the distinction between normal liver and target HCC tissues. The acidic pH of the tumor microenvironment triggers the disassembly of the RIAs, which leads to a drastic decrease in their relaxivity ratio (<I>r</I><SUB>2</SUB>/<I>r</I><SUB>1</SUB>), thus converting the RIAs from a T2 to T1 contrast agent. This inverse contrast enhancement of normal liver darkening and HCC brightening under T1 imaging mode was validated on an orthotopic HCC model. Our design provides a novel strategy for the exploitation of the next-generation intelligent MRI contrast agents.</P> [FIG OMISSION]</BR>