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      • SCOPUSKCI등재

        Experimental Research for Performance and Noise of Small Axial Fan

        Ito,,Takahiro,Minorikawa,,Gaku,Fan,,Qinyin Korean Society for Fluid machinery 2009 International journal of fluid machinery and syste Vol.2 No.2

        Small axial fans have become widely used as cooling devices in recent years. Because of their increasing importance, studies have been conducted on ways to improve the performance and reduce the noise of such fans. In this report, a small axial fan with a diameter of 85 mm (a type popularity used in personal computer or workstation) was selected for further examination. The influence on aerodynamic performance and noise of such frame design parameters as blade tip clearance results in a decrease of discrete frequency noise and an increase of broad-spectrum noise. As for the most suitable design refinement in terms of fan efficiency, we found that the treatment of outlet corner roundness and altering spoke skew to the direction counter to that of fan rotation was effective.

      • KCI등재

        전후 일본의 국가 대전략과 북일관계

        강용범 ( Jiang Long-fan ), , 왕해범 ( Wang Hai-fan ) 조선대학교 동북아문제연구소 2016 동북아연구 Vol.31 No.1

        역사적으로 한반도는 일본이 무력으로 지역패권을 도모하고 이른바 “동아시아공영권”의 야망을 실현하는 전초기지가 되어왔다. 제2차세계대전후 일본은 보통국가의 지위와 신분을 회복하고 나아가 아시아지역 강대국으로 부상하는 것을 국가전략의 최종목표로 삼아왔다. 이러한 국가전략을 실현하는 과정에 과거 식민통치에 대한 청산은 비켜설 수 없는 걸림돌이 되었다. 냉전이 한창이던 1965년, 미국의 적극적인 중재하에 한·일양국은 국교정상화를 실현하였다. 따라서 북한과의 관계개선은 전후 일본외교의 중요한 과제로 부상하게 되었다. 일본의 정치가들은 흔히 일본은 전략이 없는 국가라고 한다. 허나 냉전 이후 20여년간 전개되어 온 일본의 대북정책을 살펴보면 일본의 국가전략이 얼마나 교묘한가를 알 수 있다. 우선 북한과의 국교정상화를 통해 정상국가로서의 신분과 지위를 회복하고, 다음으로 북한의 “안전위협”을 빌미로 “군사대국화”를 실현하며, 나아가 6자회담에 끼어들어 한반도다자안보협의에 깊숙이 개입함으로써 정치, 군사 대국화를 위한 기틀을 마련하였다. 뿐만 아니라 일본의 대북정책은 반성과 사죄 그리고 배상이라는 근본적인 문제를 떠나 북한의 핵·미사일과 납치문제에만 집착하고 있다. 더욱이 일본은 중국이나 한국과의 관계가 악화되어 외교적으로 고립될 경우에는 북한과의 관계 완화를 통해 위기를 탈출하려 시도하고, 안보법안과 헌법개정을 위해선 “북한위협론”을 들먹여 제재를 강화하는 등 교묘한 전략을 구사하여왔다. 제4차 북핵실험 후 북·일관계는 또다시 최악의 위기를 맞고 있다. 북한은 일본인납치피해자에 대한특별조사위원회를 해체하였고 일본은 유엔안보리제재는 물론 독자적이고 더욱 강경한 제재를 실시하고 있다. 헌법개정을 본격적으로 추진하고 있는 아베 내각으로 말하면 북한위협이 고조되고 양국관계가 악화되는 것이 더욱 바람직한 전략적 선택일 수도 있다. In history, the Korean peninsula has been an advanced base of Japan to pursue local hegemony through force and realize an ambition to achieve Mutual Prosperity in East Asia. After World War II, Japan has had a final goal of recovering the position and status of a normal country and furthermore, raising its status to one of the top countries in Asia. In the process of realizing such a national strategy, its colonial rule in the past has become a setback which can not be overcome. In 1965 when the Cold War was at its peak period, under the active intervention of the U.S.A, South Korea and Japan normalized diplomatic relations. Therefore, a better relationship with North Korea has become an important task for Japan`s diplomacy before and after the war. Japan`s politicians said that Japan does not have any strategies. However, to look at the policies against North Korea which have been developed for about 20 years after the Cold War, it can be understood how clever Japanese strategies against other countries are. First of all, through normalization of diplomatic relations with North Korea, it recovered the status and position of a normal country. Then, under the pretext of the security threat of North Korea, it realized “Military Power” and furthermore it joined in six-party talks to intervene in the multilateral security talks and were prepared for a great military power. As well, Japan`s policy against North Korea has adhered to nuclear technology ,missiles, and kidnapping out of the fundamental problems of reflection, apology and compensation. In addition, as Japan has had worse relations with China and South Korea, and is isolated diplomatically, it attempted to escape from this crisis through mitigation of relations with North Korea, and for security law and constitution revision, it mentioned the North Korean Threat Issue to reinforce restraint. After the 4th North Korea Nuclear Test, relations between North Korea and Japan faced the worst crisis. North Korea dismantled a special investigation committee into Japanese kidnappings and Japan has implemented more independent and resolute restraints as well as restraints in the U.N. Security Council. To the Abe administration which has actively executed Constitutional reform, it is suggested that the severe threat of North Korea and aggravated relations between the two countries would be a more desirable strategy.

      • Preparation of 5-fluorouracil-loaded Nanoparticles and Study of Interaction with Gastric Cancer Cells

        Fan,,Yu-Ling,Fan,,Bing-Yu,Li,,Qiang,Di,,Hai-Xiao,Meng,,Xiang-Yu,Ling,,Na Asian Pacific Organization for Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

        Aims: To prepare 5-fluorouracil (5-Fu) nanoparticles with higher encapsulation efficiency and drug loading, and then investigate interaction with the SGC-7901 gastric cancer cell line. Materials and Methods: Prescription was optimized by orthogonal experiments, the encapsulation efficiency and loading capacity were tested by high-performance liquid chromatography, and inhibition of proliferation by 5-Fu nanoparticles and 5-Fu given to cells for 24, 48 and 72 hours was investigated by methyl thiazolyl tetrazolium assay (MTT). In addition, 5-Fu nanoparticles were labeled by fluorescein isothiocyanate (FITC), and absorption into cells was tested by flow cytometry. Results: The optimal conditions for preparation were concentrations of 5-Fu of 5mg/ml, of $CaCl_2$ of 60 mg/ml and of chitosan of 2 mg/ml. With a stirring speed of 1200rpm, encapsulation efficiency of 5-Fu nanoparticles was $55.4{\pm}1.10%$ and loading capacity was $4.22{\pm}0.14%$; gastric cancer cells were significantly inhibited by 5-Fu nanoparticles in a time and concentration dependent manner, and compared to 5-Fu with slower drug release, in a certain concentration range, inhibition with 5-Fu nanoparticles was stronger. 5-Fu nanoparticles were absorbed by the cells in line with the concentration. Conclusions: 5-Fu nanoparticles can inhibit growth of gastric cancer cells in vitro to a greater extent than with 5-Fu with good adsorption characteristics, supporting feasibility as a carrier.

      • SCIESCOPUSKCI등재

        Comparison of Microbial Diversity and Composition in the Jejunum and Colon of Alcohol-Dependent Rats

        Fan,,Yang,Ya-E,,Zhao,Ji-dong,,Wei,Yu-fan,,Lu,Ying,,Zhang,Ya-lun,,Sun,Meng-Yu,,Ma,Rui-ling,,Zhang The Korean Society for Microbiology and Biotechnol 2018 Journal of microbiology and biotechnology Vol.28 No.11

        Alcohol dependence is a global public health problem, yet the mechanisms of alcohol dependence are incompletely understood. The traditional view has been that ethanol alters various neurotransmitters and their receptors in the brain and causes the addiction. However, an increasing amount of experimental evidence suggests that gut microbiota also influence brain functions via gut-to-brain interactions, and may therefore induce the development of alcohol use disorders. In this study, a rat model of alcohol dependence and withdrawal was employed, the gut microbiota composition was analyzed by high-throughput 16S rRNA gene sequencing, and the metagenome function was predicted by PICRUSt software. The results suggested that chronic alcohol consumption did not significantly alter the diversity and richness of gut microbiota in the jejunum and colon, but rather markedly changed the microbiota composition structure in the colon. The phyla Bacteroidetes and eight genera including Bacteroidales S24-7, Ruminococcaceae, Parabacteroides, Butyricimonas, et al were drastically increased, however the genus Lactobacillus and gauvreauii in the colon were significantly decreased in the alcohol dependence group compared with the withdrawal and control groups. The microbial functional prediction analysis revealed that the proportions of amino acid metabolism, polyketide sugar unit biosynthesis and peroxisome were significantly increased in the AD group. This study demonstrated that chronic alcohol consumption has a dramatic effect on the microbiota composition structure in the colon but few effects on the jejunum. Inducement of colonic microbiota dysbiosis due to alcohol abuse seems to be a factor of alcohol dependence, which suggests that modulating colonic microbiota composition might be a potentially new target for treating alcohol addiction.

      • The Real Time Infrared Image Acquisition and Processing System Design Based on FPGA

        Fan,Jianying,Cui,Xin,Fan,Zhigang,Feng,Yao 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.2

        Field programmable gate array (FPGA) has the characteristics of high speed, low power consumption, high integration, flexibility and, small size, etc. In this paper, I design a real time infrared image processing and display system based on FPGA for the requirement of real time infrared image processing, which will realize the transmission, transformation, and storage of the image information, and then complete the infrared image edge detection based on Sobel algorithm by using this system as a platform. At last, the advantages of infrared image processing with this system compared with other methods will be verified in this paper. The experimental results show that the system spends 11.44ms on processing the colorful image whose resolution is 640480.The system has realized the real time, high speed, stable and reliable acquisition, processing and display of infrared image and we can realize the infrared target feature extraction, recognition and tracking when we combine the system with other algorithms.

      • SCOPUSKCI등재

        SEDs and Beaming Effect for Fermi Blazars

        Fan,,Jun-Hui,Yang,,Jiang-He,Liu,,Yi,Yuan,,Yu-Hai,Lin,,Cao,Xiao,,Hu-Bing The Korean Space Science Society 2016 Journal of Astronomy and Space Sciences Vol.33 No.2

        In this work, based on our previous calculations of spectral energy distributions for a sample of Fermi blazars (Fan et al. 2015a), we calculated the radio loudness and performed correlation analyses. Our analysis results show that radio loudness is closely anti-correlated with synchrotron peak frequency and positively correlated with gamma-ray luminosity, suggesting that the gamma-ray emissions are strongly beamed.

      • KCI등재

        A template-hatched method towards poly(acrylic acid) hydrogel spheres with ultrahigh ion exchange capacity and robust adsorption of environmental toxins

        Fan,Yang,Xin,Fan,Man,Zhang,Chen,Wang,Wei-Feng,Zhao,Chang-Sheng,Zhao 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.69 No.-

        Polyacrylic acid/polyethersulfone (PAA/PES) capsules were adopted as templates to synthesize PAA/PES core–shell spheres, and the PES shell of spheres could be removed automatically by the swelling nature of the cross-linked PAA hydrogel core. By using the method, PAA hydrogel spheres were prepared with an ultrahigh ion exchange capacity of 12 meq g−1, and the spheres showed a high adsorption capacity for methylene blue. The PAA-polyacrylamide hydrogel spheres with dual adsorption ability and good mechanical property were also prepared. It was revealed that these two hydrogel spheres can be effectively utilized in the removal of environmental toxins.

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