法醫學者 崔棟

박의우,여인석 大韓法醫學會 1994 대한법의학회지 Vol.18 No.1

Forensic medicine in modern sense was introduced in early 20th century in our country. The first Korean forensic pathologist among medical school graduates was Dr. Choy Dong, who graduated from Severance Union Medical College(SUMC) in 1921. He was born in 1896 at Seoul, and entered SUMC in 1918. He went to Department of Forensic Medicine, Tohoku University Medical College, Sendai, Japan, and researched in the field of forensic medicine. He returned to Korea in 1936 and became a lecturer of forensic medicine. He had also lectured clinical pathology and parasitology. He resigned SUMC in 1948 because of some uncertain reasons.

분포 증발산량 산정 결과의 격자형 GIS 표현

박진혁,황의호,이근상,채효석 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.4

본 연구에서는 원격탐사나 지리정보시스템 등을 적응하여 ASCII형태의 수지표고자료와 원격탐사 자료를 이용하여 분류한 토지피복도를 이용하여 각 토지피복별로 알베도와 바로크계수, 증발효율 등을 이용할 수 있는 격자형 토지피복자료를 격자단위로 분할하여 모형의 입력값으로 이용하였기 때문에 유역의 공간적인 특성을 반영한 덜다 정확하고 신뢰성있는 자료의 구축이 가능했고, 기존의 열수지법을 이용하여 증발산량의 시 공간적인 분포양상을 계산할 수 있는 격자기반의 분포형 증발산량 추정 프로그램을 포트란언어고 개발하였으며, 격자형 증발산량 산정 모형은 향후 연될 격자기반의 분포형 강우-유출모형과 통합할 수 있도록 고려하였다. 또한, 격자기반의 계산으로 증발산량에 대한 유역내 특정지점에서의 시7)적 변화 양상과 공간적 분포 양상을 GIS상에서 나타낼 수 있도록 구성하였다. 모형의 적용성 검증을 위해서 비교적 정화한 기상자료와 수문자료를 보유하고 있는 일본의 쇼나이강 유역(532㎢)을 대상으로 적응한 결과, 유역 연평균 증발산량은 825.4mm로 나타났다. A Grid-based distributed evaporation prediction model which calculates temporal and spatial evaporation with a heat balance method was developed. And, the model was considered as the integration with distributed hydrological model in near future. This model was programmed by fortran language and used ASCII formatted map data of DEM (Digital Elevation Model) and land cover map extracted by remote sensing data. Also, temporal variations and spatial distributions of evaporation are presented by using GIS. To verify the applicability of the model, it was applied to the Shonai river basin (532㎢) which has sufficient meteorological and hydrological data, Japan. The result shows that the estimated mean annual evaporation was 825.41nm, and this value is estimated as suitable things in considering rainfall and discharge data in study area.

Comparison of concurrent chemoradiotherapy with cisplatin plus 5-fluorouracil versus cisplatin plus paclitaxel in patients with locally advanced cervical carcinoma

Eui-Sok Sol,이태성,Suk Bong Koh,Hun Kyu Oh,Gi Won Ye,최윤석 대한부인종양학회 2009 Journal of Gynecologic Oncology Vol.20 No.1

Objective: The aim of this study was to compare survival outcomes and toxicities between concurrent radiotherapy with cisplatin plus 5-fluorouracil and that with cisplatin plus paclitaxel in patients with locally advanced cervical carcinoma. Methods: We retrospectively reviewed data from 93 locally advanced cervical carcinoma patients (stage IB to IVA) who had been treated by concurrent radiotherapy with cisplatin plus 5-fluorouracil (CF, n=45) vs. cisplatin plus paclitaxel (CP, n=48) as primary therapy. Toxicities and survival outcomes were compared. Results: In the CP group, there were higher frequencies of severe (grade 3 or 4) leukopenia (79.2%, as compared to 11.1% in the CF group), severe neutropenia (77.1%, as compared to 8.9% in the CF group) and severe peripheral neuropathy (12.5%, as compared to 2.2% in the CF group). In the CF group, there were higher frequencies of severe nausea (33.3%, as compared to 14.6% in the CP group) and severe hyponatremia (11.1%, as compared to 0% in the CP group). Five-year DFS of the CF and CP groups was 67.4% and 79.1%, respectively (p=NS). Five year OS of the CF and CP groups was 79.6% and 80.9%, respectively (p=NS). Conclusion: Concurrent radiotherapy with cisplatin plus paclitaxel showed increased leukopenia, neutropenia and peripheral neuropathy, but less gastrointestinal toxicity (nausea) than that with cisplatin plus 5-fluorouracil. Survival outcome between these two groups was not statistically different in this study. Large prospective randomized controlled studies will be needed to confirm this result. Objective: The aim of this study was to compare survival outcomes and toxicities between concurrent radiotherapy with cisplatin plus 5-fluorouracil and that with cisplatin plus paclitaxel in patients with locally advanced cervical carcinoma. Methods: We retrospectively reviewed data from 93 locally advanced cervical carcinoma patients (stage IB to IVA) who had been treated by concurrent radiotherapy with cisplatin plus 5-fluorouracil (CF, n=45) vs. cisplatin plus paclitaxel (CP, n=48) as primary therapy. Toxicities and survival outcomes were compared. Results: In the CP group, there were higher frequencies of severe (grade 3 or 4) leukopenia (79.2%, as compared to 11.1% in the CF group), severe neutropenia (77.1%, as compared to 8.9% in the CF group) and severe peripheral neuropathy (12.5%, as compared to 2.2% in the CF group). In the CF group, there were higher frequencies of severe nausea (33.3%, as compared to 14.6% in the CP group) and severe hyponatremia (11.1%, as compared to 0% in the CP group). Five-year DFS of the CF and CP groups was 67.4% and 79.1%, respectively (p=NS). Five year OS of the CF and CP groups was 79.6% and 80.9%, respectively (p=NS). Conclusion: Concurrent radiotherapy with cisplatin plus paclitaxel showed increased leukopenia, neutropenia and peripheral neuropathy, but less gastrointestinal toxicity (nausea) than that with cisplatin plus 5-fluorouracil. Survival outcome between these two groups was not statistically different in this study. Large prospective randomized controlled studies will be needed to confirm this result.

자궁경부상피의 암화과정에 있어서 Cytokeratins 및 Ki-67의 발현과 인유두종 바이러스 16, 18형의 감염

설의석 ( Eui Sok Sol ),한치동 ( Chi Dong Han ),이태성 ( Tee Sung Lee ),고석봉 ( Suk Bong Koh ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.6

목적 : 자궁경부상피의 암화과정과 CKs, Ki-67, HPV 16, 18의 발현연관성을 규명하고자 한다. 연구 방법 : 대구가톨릭대학병원에서 조직생검을 하거나 원추절제술 또는 자궁적출술을 시행하여 얻은 조직중에서 정상, LSIL, HSIL, Squamous cell carcinoma로 확진된 각각 30명의 환자 조직을 대상으로 CKs, Ki-67, HPV 16, 18의 발현을 조사하였다. 결과 : CK 14와 13은 자궁경부조직에서 병변이 진행함에 따 Objective : To evaluate the relationship between the expression of cytokeratins, Ki-67 and the infection of human papillomavirus 16, 18 type in the carcinogenic progrssion of the uterine cervical epithelium. Methods : Investigation the expression patterns

수술 창상부위에 재발한 자궁경부암

설의석 ( Sol Eui Sok ),이태성 ( Lee Tae Seong ),김은진 ( Kim Eun Jin ),최윤석 ( Choi Youn Seok ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.7

Incisional metastases following surgery for cervical cancer are extremely rare. We report a case of a recurrence which occurred at a incisional site following radical hysterectomy and pelvic lymphadenectomy for squamous cell carcinoma of the cervix. The recurrence was found at the incisional site just below umbilicus that was not included for post-operative adjuvant radiotherapy. We performed wide local excision and postoperative adjuvant radiotherapy for 5 weeks. She has been under follow up until now, and there is no evidence of recurrence.

국토관측센서 기반 수재해 정보플랫폼 융합기술연구단 소개

채효석(Hyo Sok Chae),황의호(Eui Ho Hwang),김동영(Doung Young Kim),백승협(Seung Hyub Baeck),강동일(Dong Il Kang) 대한토목학회 2017 대한토목학회지 Vol.65 No.3

뇌수막염을 일으킨 쯔쯔가무시병 1예

류센,황의창,김인호,홍석균,배현주,이근호 대한감염학회 1999 감염 Vol.31 No.3

Tribochemical interactions of Si-doped DLC film against steel in sliding contact

Duc-Cuong Pham,Eui-Sung Yoon(윤의성),Ho-Sung Kong(공호성),Hyo-Sok Ahn(안효석) 한국트라이볼로지학회 2006 한국트라이볼로지학회 학술대회 Vol.2006 No.6

This study concerns the effects of tribochemical interactions at the interface between Si-DLC (silicon-doped diamond-like carbon) film and steel ball in sliding contact on tribological properties of the film. The Si-DLC film was deposited on DLC/Si substrate using radio frequency plasma-assisted chemical vapor deposition (r.f. PACVD) with different Si concentration. Friction tests against steel ball using a reciprocating type wear tester were performed in ambient environment. X-Ray photoelectron spectroscopy (XPS) and auger electron spectroscopy (AES) were used to study the chemical characteristics and elemental composition of the film and mating balls after tests. As results, a dark-gray transfer film consists of carbon, oxygen and silicon elements were observed on worn surface of steel ball with different thickness. The oxidation of Si-DLC surface and steel ball was also identified at particular regions of contact area. On the contrary, the transfer film could not be found on surface of the ball slid against pure DLC coating. This demonstrates that chemical reactions were occurred at contact area of Si-DLC and steel ball during sliding. While friction test of DLC film versus steel ball exhibited high friction coefficient (~0.06), the Si-DLC in its turn showed very low friction (~0.022) with the presence of tribofilm on mating ball surface. However, Si-DLC film possesses poor wear resistance in comparison with the pure DLC. We suggest that the tribochemical process strongly affected to tribological properties of the Si-DLC film in sliding against steel.

Preparation and Stability Evaluation of Docetaxel-Loaded Oral Liposome

( Hyun Mi Kim ),( Eui Chaul Oh ),( Chong Run Chon ),( Pung Sok Lee ),( Ma Se Lee ) 한국약제학회 2010 Journal of Pharmaceutical Investigation Vol.40 No.2

Friction and wear properties of boron carbide coating under various relative humidity

Pham Due Cuong,Hyo-Sok Ahn,Kyung-Ho Shin,Eui-Sung Yoon 한국트라이볼로지학회 2005 한국트라이볼로지학회 학술대회 Vol.2005 No.11

Friction and wear properties of the Boron carbide (B₄C) coating 100 nm thickness were studied under various relative humidity (RH). The boron carbide film was deposited on silicon substrate by DC magnetron sputtering method using B₄C target with a mixture of Ar and methane (CH₄) as precursor gas. Friction tests were performed using a reciprocation type friction tester at ambient environment. Steel balls of 3mm in diameter were used as counter-specimen. The results indicated that relative humidity strongly affected the tribological properties of boron carbide coating. Friction coefficient decreased from 0.42 to 0.09 as the relative humidity increased from 5% to 85%. Confocal microscopy was used to observe worn surfaces of the coating and wear scars on steel balls after the tests. It showed that both the coating surface and the ball were significantly worn-out even though boron carbide is much harder than the steel. Moreover, at low humidity (5%) the boron carbide showed poor wear resistance which resulted in the complete removal of coating layer, whereas at the medium and high humidity conditions, it was not. X-ray photoelectron spectroscopy (XPS) and Auger electron spectroscopy (AES) analyses were performed to characterize the chemical composition of the worn surfaces. We suggest that tribochemical reactions occurred during sliding in moisture air to form boric acid on the worn surface of the coating. The boric acid and the tribochemcal layer that formed on steel ball resulted in low friction and wear of boron carbide coating.