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Yoon, Shin-Eui,Park, Sangwook,Ahn, Sung Gyun Yeungnam University College of Medicine 2018 Yeungnam University Journal of Medicine Vol.35 No.1
The radial artery is generally the preferred access route in coronary angiography and coronary intervention. However, small size, spasm, and anatomical variations concerning the radial artery are major limitations of transradial coronary intervention (TRI). We describe a successful case involving a patient with coronary artery disease who underwent TRI via a well-developed radial recurrent artery branch from the radioulnar alpha loop using a sheathless guiding catheter.
Yoon, Ji Hyun,Lee, Bong Sang,Yoon, Eui Pak Trans Tech Publications, Ltd. 2007 Key Engineering Materials Vol.353 No.-
<P>The present study is a systematic investigation of the effects of microstructural changes, which have originated from the variations of filler metals and welding processes, on the J-R properties of simulated welds. Two AISI Type 347 weld metals, with different carbon contents, deposited by a GTAW process and two AISI Type 347 weld metals, with different carbon contents, deposited by a SMAW process were used in this study. The J-R tests were conducted at 316oC (600oF). The welds deposited by the GTAW process showed higher fracture resistances when compared to the welds deposited by the SMAW process. The J-R fracture resistance of the Type 347-GTAW processed weld with high carbon content was remarkably low when compared to the weld with low carbon. The J-R fracture resistances were decreased by coarse Nb(C, N) precipitates in the Type 347 weld deposited by the GTAW process. In the case of the SMAW welds, mainly coarse Ti-rich particles which had originated from the shielding of the welding rods deteriorated the fracture resistances.</P>
Yoon, Shin-Eui,Ahn, Sung Gyun,Kim, Jang-Young,Park, Jin-Sun,Shin, Joon-Han,Tahk, Seung-Jea,Lee, Su-Kyeong,Kim, Tae-Jin,Han, Na The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.7
<P>Whether the metabolic syndrome (MetS) has prognostic value for coronary artery disease (CAD) beyond its individual components is controversial. We compared the relationship between the number of MetS components and CAD severity as assessed by angiography in non-diabetic and diabetic subjects. We consecutively enrolled 527 patients who underwent their first coronary angiography. Patients were divided into four groups according to the number of MetS components: 0/1, 2, 3, and 4/5. A coronary atherosclerosis score was used to quantify the extent of atherosclerotic involvement. The relationship between the MetS score and angiographic CAD severity or clinical presentation was compared between non-diabetic and diabetic subjects. Individuals with the MetS (n = 327) had a higher prevalence of CAD (60% vs 32%, <I>P</I> < 0.001), multi-vessel disease (34% vs 16%, <I>P</I> < 0.001), and acute coronary syndromes (49% vs 26%, <I>P</I> < 0.001) than those without the MetS. In the non-diabetic group, atherosclerosis score increased with the MetS score (1.0 ± 2.1, 2.0 ± 2.9, 2.8 ± 2.9, and 3.6 ± 3.9, <I>P</I> < 0.001) whereas there was no significant difference in the diabetic group (0.5 ± 1.0, 5.2 ± 4.7, 4.2 ± 2.9, and 4.4 ± 3.5, <I>P</I> = 0.102). The MetS score is related to CAD severity in non-diabetic patients but the association between the MetS score and angiographic CAD severity may be obscured in the presence of diabetes.</P>
Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness
Sung, Pil Soo,Cheon, HyeonJoo,Cho, Chung Hwan,Hong, Seon-Hui,Park, Do Youn,Seo, Hyung-Il,Park, Su-Hyung,Yoon, Seung Kew,Stark, George R.,Shin, Eui-Cheol Proceedings of the National Academy of Sciences 2015 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.112 No.33
Sung, Pil Soo,Shin, Eui-Cheol,Yoon, Seung Kew MDPI 2015 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.16 No.10
<P>Hepatitis C virus (HCV) is a positive-stranded RNA virus that infects approximately 130–170 million people worldwide. In 2005, the first HCV infection system in cell culture was established using clone JFH-1, which was isolated from a Japanese patient with fulminant HCV infection. JFH-1 replicates efficiently in hepatoma cells and infectious virion particles are released into the culture supernatant. The development of cell culture-derived HCV (HCVcc) systems has allowed us to understand how hosts respond to HCV infection and how HCV evades host responses. Although the mechanisms underlying the different outcomes of HCV infection are not fully understood, innate immune responses seem to have a critical impact on the outcome of HCV infection, as demonstrated by the prognostic value of IFN-λ gene polymorphisms among patients with chronic HCV infection. Herein, we review recent research on interferon response in HCV infection, particularly studies using HCVcc infection systems.</P>