Magnetic resonance images of ameloblastoma

Kim, Jae-Duk,Kim, Jin-Soo 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

Purpose : To classify and describe the characteristic features of MRI of some ameloblastoma variants. Materials and Methods : The MR images, CT images, and panoramic radiographs in 5 cases were retrospectively examined as follows. First, the contents of ameloblastomas were devided into two portions of either solid or cystic components on the basis of MR signal intensities. The signal intensity within the solid or cystic portions was classified as homogeneous or heterogeneous. Next, the characteristic internal feature of the lesion on T1W1 or T2WI was described. The signal intensities were classified into low, intermediate, slightly high, high, and strong high signal intensity. Results : Unicystic lesion showed homogeneous high signal intensity (SI) on T2W2 and the rim enhancement of the surrounding area including the mural nodule and the thick wall except the central portion on Gd-T1W1 Solid type revealed heterogeneous and high SI area with strong high SI area on T2W2. On Gd-T1W1, the area corresponding to the low signal spot on T1W1 and the strong high signal spot on T2W1 showed low SI. Hybrid type showed slightly enhanced capsular structures and low SI for the round bony septa and the areas connecting the mixed and cystic lesions on T2W1 and Gd-T1W1. Conclusion : MRI could easily assess the relationship between the mixed and cystic findings in ameloblastoma.

Metastatic hepatocellular carcinoma on the mandible : A case report

Kim, Jin-Soo,Kim, Jae-Duk 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

Hepatocellular carcinoma is one of the most common cancer worldwide, primarily affecting those in regions with a high prevalence of viral hepatitis. However, the metastasis of hepatocellular carcinoma to the oral cavity is a rare phenomenon. This report presents a case of metastatic hepatocellular carcinoma in the left mandibular angle and ramus region of a 62-year-old man. Panoramic radiograph revealed an ill-defined radiolucent lesion extending from the retained root of the mandibular left second molar into the ascending ramus. The lesion had irregular and ill-defined margins.

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).

만성적 과부하에 따른 골격근의 수축특성과 근섬유 Isoform 조성의 변화 분석

유덕수,권혁중,권만근 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.2

The effects of chronic overload by synergist ablation (SA) on fiber type, myosin heavy chain (MyoHC) isoforms, and contractile properties in the rat plantaris muscle were studied. Plantaris muscle was overloaded by bilateral removal of its synergist of gastrocnemius muscle in Fischer 344 female rats (aged 8 pweeks). Muscles of sham-operated legs served as controls. The overloaded plantaris was 20% heavier than control 3 week after SA. Overload by SA resulted in remarkable increases in cross-sectional areas of muscle fibers of all types : however the percentage increase was less in type Ⅱb fibers. Twitch contraction and half-relaxation time before and after tetanus did not change, but fatigue resistance increased significantly with overload. The percentage of area occupied by type Ⅱb fibers, which have lower oxidative capacity, decreased while the percentage of area occupied by other type Ⅱ fibers, but not tupe I fibers, increased. Analysis of MyoHC isoforms with gradient sodium dodecylsulfate polyacrylamide gel electrophoresis revealed a decrease in Ⅱb isoforms and an increase in Ⅱd isoforms. There results suggest that chronic overload produces changes in muscle fiber type and MyoHC isoform compositions which partly account for increased fatigue resistance in overloaded muscles.

주정박 사일리지 제조시 인삼박의 혼합이 사일리지의 품질에 미치는 영향

이수기,이인덕,김용국 충남대학교 농업과학연구소 2001 농업과학연구 Vol.28 No.1

본 연구에서는 타피오카 주정박에 인삼박을 혼합하여 사일리지를 제조하였을 때, 사일리지의 품질(실험 Ⅰ)과 건물 섭취량 및 소화율 (시험 Ⅱ)에 미치는 영향을 조사하였다. 사일리지 조제시 수분함량을 낮추기 위하여 소맥피를 10% 수준으로 첨가하였으며, 인삼박의 혼합비율은 원물기준으로 0, 15 및 30% 수준 (3 처리)으로 하였다. 처리당 5반복으로 20㎏ 씩 비닐백에 넣고 공기를 배제하여 포장한 후 20∼25℃에서 30일간 숙성시켜 공시하였다. 시험 Ⅱ의 소화시험에서는 10개월령의 재래산양 수컷12두 (평균체중 14㎏)를 공시하여서 처리당 4반복이 되게 하였다. 7일 동안의 적응기간을 거친 후, 5일간 소화율을 조사하였던 바, 얻어 진 결과를 요약하면 다음과 같다. 1. 인삼박의 혼합 비율이 증가함에 따라 조단백질, NDF 및 ADF의 양이 증가하는 경향을 나타내었으며, 특히 인삼박 30% 첨가구는 인삼박 무첨가구와 인삼박 15% 첨가구에 비하여 유의하게 높은 결과를 나타내었다 (P<0.05). 그리고 조지방 함량과 hemicellulose 함량은 처리구간에 유의한 차이가 인정되지 않았다. 2. pH는 인삼박을 혼합하므로서 유의하게 감소하였으며, 인삼박 처리구간에는 유의한 차이가 인정되지 않았다. 젖산 함량은 인삼박 혼합비율이 증가함에 따라 유의하게 많아졌으며 (P<0.05), 총산도 인산박 첨가구가 무첨가구에 비하여 유의하게 많은 결과를 나타냈다. 초산은 인삼박 30% 첨가구가 유의하게 적었다. 한편 낙산은 인삼박 첨가구가 무첨가구에 비하여 유의하게 적었다(P<0.05) 3. 사일리지의 섭취량은 인삼박 첨가구가 무첨가구 보다 유의하게 많았다. 건물 소화율은 인삼박을 많이 혼합할수록 증가하였다. 위의 결과로 볼 때 주정박에 인삼박을 혼합하여 사일리지를 조제하는 것은 주정박 안으로 조제할 때 보다 더 좋은 품질의 사일리지를 만들 수 있으며, 기타 유사 재료에 대해서도 광범위한 적용이 가능할 것으로 사료된다. Two experiments were conducted to investigate the effects of the addition of ginseng meal to distillers feed on the silage quality, and feed intake and matter (DM) digestibility in goats In Experiment I , three levels of ginseng meal (0, 15, and 30%) were added to the distillers feed to make three types (treatment) of distillers feed silages (DFS). There were five replicates per treatment. Samples of 20 kg each were put into vinyl bag and vacuumed by an air compressor Vinyl bags mere kept at 20-25℃ for 30 days before being analyzed In Experiment Ⅱ. 12 male Korean native goats were employed to investigate the DM intake and digestibility of silages from Experiment I There n-ere 4 replicates per treatment. Daily feed intakes and fecal excretion were measured In Experiment I. the silage pH decreased and the lactic acid increased significantly by the addition of ginseng meal (P<005) In Experiment Ⅱ, the feed intake and DM digestibility increased significantly by the addition of ginseng meal It appears that the quality of distillers feed silages could be improved by the addition of ginseng meal at the level of 15 to 30%.

難燃劑 添加 Poly Alkyl Methacrylate의 劣化에 관한 硏究

薛秀德,金東建 동아대학교 공과대학 부설 한국자원개발연구소 1991 硏究報告 Vol.15 No.1

The thermal degradation of poly alkyl methacrylate and flame-retardant tetrabromobisphenol-A(TBBA) mixtures were carried out using the thermogravimetric method in the stream of nitrogen gas with 50㎖/min at the various heating rate from 4 to 20℃/min. Friedman and Ozawa mathematical methods were used to obtain the value of activation energy. The thermal degradation of poly alkyl methacrylate and TBBA mixtures by the analysis of infrared spectrophotometer were decomposed by main chain scission in the stream of nitrogen.

헝가리 회계시스템과 한국 회계시스템의 비교

서수덕 국제지역학회 1997 국제지역연구 Vol.1 No.2

해외투자와 세계무역의 현저한 증대, 다국적 기업화, EU와 같은 지역경제 집단의 형성 및 동구 공산권의 시장경제로의 이행 등의 현상으로 인해 특히 회계기준이 복잡하게 되고 있다. 따라서 회계 처리방법, 평가방법이나 인식과 같은 절차상의 차이를 정확히 이해하지 못하면 재무자료의 분석이 무의미해 진다. 이런 면에서 최근에 회계제도의 국제적 비교가 활발히 이루어지고 있다. 특히 최근에 시장경제체제로 이행한 동구권회계제도에 대한 연구가 필요한 실정이다. 보고책임이라는 기본적인 목표를 갖고 있는 회계는 헝가리에서의 추가적 개혁의 주안점이 되었으며 그 일환으로 "Hungarian Rules of Law in Force"로 불리우는 회계법이 1991년에 통과되었다. 그 법의 기본적인 목적은 헝가리의 회계실무를 서구 유럽기준과 보조를 맞추고 비효율적인 활동을 재구축하거나 혹은 마감하는 것이었다. 그러나 이러한 헝가리회계제도도 서구의 그것 특히, 우리나라의 회계제도와는 큰 차이를 보이고 있다. 회계차이는 투자가들의 투자의사결정에 영향을 미치고 더욱이 상이한 회계 및 보고요건들로 인해 재무적 결과의 분석에 여러 가지 어려움이 야기될 수 있다. 그 차이들은 세계적 자본시장의 효율적 기능에 대하여 장애물이 된다. 또 이러한 회계적 차이를 손익계산서와 대차대조표 척도 효율적 기능에 대하여 장애물이 된다. 또 이러한 회계적 차이를 손익계산서와 대차대조표 척도의 비교에 영향을 미치고 자본의 적절성, 신용의 정당성, 주주지분의 척도 및 자본비용에 영향을 미칠 수 있다. 본 연구에서는 초기투자결정 및 계속적인 재무관리분석에 영향을 미칠 수 있는 헝가리회계법과 우리나라의 회계기준 간의 차이를 부각시키는데 주안점을 두고 있다. 양회계 제도를 비교분석함으로써 동구권 시장에 진출하고 있거나 하려는 우리나라 기업들이 그 시장에 대한 재무적 정보를 보다 체계적이고 효율적으로 이용할 수 있으리라 여겨진다. 따라서 본 연구는 헝가리 회계법에서 제시된 회계의 기본목적을 살펴본 후 투자와 신용 및 관리적 의사결정에 중요하다고 여겨지는 헝가리와 우리나라의 회계 및 보고 간의 특수한 비교를 행하였다. 회계제도의 비교는 회계기준의 설정·내용·운용·교육 및 그 경제적 환경조건에 따라 행해져야 한다. 그러나 여기서는 헝가리의 회계제도의 내용과 회계제도의 운용에 한정하여 우리나라 회계제도와 비교하였다. 마지막으로 기관 투자자들과 경영자들을 위한 시사점들을 검토하였다.

플라이애쉬 콘크리트의 特性에 미치는 굵은 骨材 最大値數의 影響에 관한 實驗的 硏究

김덕현,유영주,이상수,송하영,김을용 한밭대학교 2004 한밭대학교 논문집 Vol.21 No.-

In this study, the experiment was carried out to investigate and analyze the influence of coarse aggregate's maximum size and Fly Ash replacements ratio on the properties of concrete. The main experimental variables were water/cement ratio 45 and 65(%), maximum size of coarse aggregate 15, 25 and 40(mm), Fly Ash replacements ratio 0, 10, 20(%). According to the test results, the principal conclusions are summarized as follows. 1) The slump and flow of fresh concrete were found to be higher in the order of maximum size of coarse aggregate 15, 25 and 40(mm), also in the order of Fly Ash replacements ratio 0, 10, 20(%). 2) The compressive strength of hardened concrete were found to be lower in the order of maximum size of coarse aggregate 15, 25 and 40(mm). While, Fly Ash replacements ratio increases in age 7days, showed tendency that compressive strength increases together. but, age 28, 56(day) were showed opposite tendency.

은행엽 물추출물이 흰쥐의 흉부대동맥 혈관이완에 미치는 영향

鄭權洙,金亨煥,安德均,崔湖榮 대한본초학회 2001 大韓本草學會誌 Vol.16 No.2

We have examined the relaxational response of the Ginkgo Folium water extract on isolated thoracic aorta from sprague dawley rat (300~350g) in the presence and absence of endothelium and the vasodilator nitric oxide. Segments of thoracic aorta obtained from rats immediately after delivery were mounted in organ baths superfused on a polygraph. We found that the thoracic aorta segments responded to the Ginkgo Folium water extract with a dose-dependent vasorelaxation. At 2.0 ㎎/㎖ Ginkgo Folium water extract, the relaxational response with and without endothelium were 75.8% and 6.9% of the maximum KCI-response. The Phenylepinephrine and 5-hydroxytrptamine - induced contraction at 10^-4M were inhibited by 77.3% and 75.8% after addition(2.0 ㎎/㎖) of the Ginkgo Folium water extract. After pre-treatment of the thoracic aorta with N^G-monomethyl-L-arginine(10^-4M), the vessels contracted in response to the nitric oxide synthase inhibitor. The present results show that nitric oxide may act as a crucial signal in the vasodilative action. In conclusion, Ginkgo Folium water extract-induced relaxation in the isolated rat thoracic aorta was composed of endothelium-dependent and dose-dependent relaxation. Endothelium-dependent relaxation may be mediated by release of endothelium derived relaxing factor, nitric oxide.

천연 제올라이트에 의한 중금속 이온의 제거

김덕수,감상규 濟州大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.10 No.2

The three natural zeloites collected in Pohang-shi and Kyeongju-shi, Kyungsangbug-do, Korea, were analyzed by means of X-ray fluorescence and X-ray diffraction. from the results, the primary species of those zeolite were mordenite and clinoptilolite mixed with quartz. These zeloites were chemically treated with NaOH, Ca(OH)??, and NaOH following HCl solution. The capabilities of removing divalent heavy metal ions, such as Cu??and Sr?? with chemically untreated and treated natural zeolites were investigated and compared in the single and mixed heavy metal ion solutions with varying initial heavy metal ion concentration and pH of solution. It was found that Daeshin-ri natural zeolite(D) was most efficient in removing Cu?? and Sr?? ions. The chemical treatment of natural zeloite improved the capabilities of removing Cu?? and Sr?? ions and the most effective chemical treatment of natural zeolite was NaOH treatment. The capabilities of removing Cu??and Sr?? ions in mixed ions solution were lower than those in single ion solution. The three natural zeolites collected in Pohang-shi and Kyeongju-shi, Kyungsangbug-do, Korea, were analyzed by means of X-ray fluorescence and X-ray diffraction. From the results, the primary species of those zeolite were mordenite and clinoptilolite mixed with quartz. These zeolites were chemically treated with NaOH, Ca(OH)₂, and NaOH following HCl solution. The capabilities of removing divalent heavy metal ions, such as Cu²+ and Sr²+ with chemically untreated and treated natural zeolites were investigated and compared in the single and mixed heavy metal ion solutions with varying initial heavy metal ion concentration and pH of solution. It was found that Daeshin-ri natural zeolite(D) was most efficient in removing Cu²+ and Sr²+ ions. The chemical treatment of natural zeolite improved the capabilities of removing Cu²+ and Sr²+ ions and the most effective chemical treatment of natural zeolite was NaOH treatment. The capabilities of removing Cu²+ and Sr²+ ions in mixed ions solution were lower than those in single ion solution.