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연산자 조작 공격과 피연산자 조작 공격에 대한 기존 CRT-RSA Scheme의 안전성 분석
허순행(Soonhaeng Hur),이형섭(Hyungsub Lee),이현승(Hyunseung Rhee),최동현(Donghyun Choi),원동호(Dongho Won),김승주(Seungjoo Kim) 한국정보보호학회 2009 정보보호학회논문지 Vol.19 No.6
CRT-RSA의 사용이 대중화됨에 따라, CRT-RSA에 대한 보안 또한 중요 이슈가 되었다. 1996년, Bellcore 연구원들에 의해 CRT-RSA가 오류 주입 공격에 취약하다고 밝혀진 이래로, 많은 대응책들이 제안되었다. 첫 번째 대응책은 1999년 Shamir에 의해 제안되었으며, Shamir의 대응책은 오류 검사 기법에 기반을 두고 있다. Shamir의 대응책이 소개된 이후, 오류 검사 기법을 사용하는 많은 대응책들이 제안되었다. 그러나 Shamir의 대응책은 2001년 Joey 등에 의하여 피연산자 조작 공격에 취약함이 밝혀졌으며, 오류 검사 기법 또한 2003년 Yen 등에 의하여 연산자 조작 공격에 취약하다고 알려졌다. 이에 Yen 등은 오류 검사 기법을 사용하지 않고 오류 확산 기법을 사용하여 새로운 대응책을 제안하였으나, Yen 등이 제안한 대응책 또한 2007년에 Yen과 Kim에 의하여 안전하지 않음이 밝혀졌다. 최근에는 Kim 등이 Yen 등의 대응책을 보완한 새로운 대응책을 제안하였으며, Ha 등 또한 오류 확산 기법을 사용한 대응책을 제안하였다. 그러나 Kim 등과 Ha 등이 제안한 대응책들을 포함한 기존 대응책들은 연산자 조작 공격에 대해서는 안전성이 증명되지 않았기 때문에 본 논문에서는 피연산자 조작 공격은 물론, 연산자 조작 공격도 고려하여 지금까지 제안된 대응책들의 안전성을 분석할 것이다. As the use of RSA based on chinese remainder theorem(CRT-RSA) is being generalized, the security of CRT-RSA has been important. Since Bellcore researchers introduced the fault attacks on CRT-RSA, various countermeasures have been proposed. In 1999, Shamir firstly proposed a countermeasure using checking procedure. After Shamir's countermeasure was introduced, various countermeasures based on checking procedure have been proposed. However, Shamir's countermeasure was known to be vulnerable to the modified operand attack by Joey et al. in 2001, and the checking procedure was known to be vulnerable to the modified opcode attack by Yen et al. in 2003. Yen et al. proposed a new countermeasure without checking procedure, but their countermeasure was known to be also vulnerable to the modified operand attack by Yen and Kim in 2007. In this paper, we point out that pre, but countermeasures were vulnerable to the modified operand attack or the modified opcode attack.
Kim, Sungchul,Lee, Sanghyun,Shin, Jinwook,Kim, Youngkyun,Evnouchidou, Irini,Kim, Donghyun,Kim, Young-Kook,Kim, Young-Eui,Ahn, Jin-Hyun,Riddell, Stanley R,Stratikos, Efstratios,Kim, V Narry,Ahn, Kwangs Nature Publishing Group, a division of Macmillan P 2011 NATURE IMMUNOLOGY Vol.12 No.10
Major histocompatibility complex (MHC) class I molecules present peptides on the cell surface to CD8<SUP>+</SUP> T cells, which is critical for the killing of virus-infected or transformed cells. Precursors of MHC class I??presented peptides are trimmed to mature epitopes by the aminopeptidase ERAP1. The US2??US11 genomic region of human cytomegalovirus (HCMV) is dispensable for viral replication and encodes three microRNAs (miRNAs). We show here that HCMV miR-US4-1 specifically downregulated ERAP1 expression during viral infection. Accordingly, the trimming of HCMV-derived peptides was inhibited, which led to less susceptibility of infected cells to HCMV-specific cytotoxic T lymphocytes (CTLs). Our findings identify a previously unknown viral miRNA??based CTL-evasion mechanism that targets a key step in the MHC class I antigen-processing pathway.
Selective removal of rotifers in microalgae cultivation using hydrodynamic cavitation
Kim, Donghyun,Kim, Eun Kyung,Koh, Hyun Gi,Kim, Kyochan,Han, Jong-In,Chang, Yong Keun Elsevier Science B.V. Amsterdam 2017 Algal research Vol.28 No.-
<P><B>Abstract</B></P> <P>Rotifers in algal open ponds consume microalgae rapidly, eventually causing the pond to crash. Hydrodynamic cavitation (HC) has been suggested as a means of controlling rotifers, and its effect on <I>Nannochlropsis salina</I> was examined here. Rotifers were removed at a rate of 87% after a single pass of HC when the initial concentration was 1000 individuals/mL, and up to 99% after four passes, regardless of the initial concentration. The removal rate is expected to be higher than 96% with a single pass in an actual pond, as the rotifer concentration does not typically exceed 500individuals/mL, even under favorable environmental conditions. At the same intensity of HC, the reproductive capability of <I>N</I>. <I>salina</I> dropped by 12–15% however, the growth exhibited a constantly increasing overall tendency. In addition, the applied HC process was found to be the most energy efficient approach among the existing physical methods for controlling zooplanktons, requiring 6MJ of energy for treating 1m<SUP>3</SUP> of algal suspension. Rotifers were sufficiently vulnerable and algae were relatively tolerant to the HC, and therefore HC can be adopted as a selective crop-protection method in microalgae cultivation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Rotifer control is a challenging problem in outdoor cultivation of microalgae. </LI> <LI> Hydrodynamic cavitation (HC) was found to be effective for rotifer removal. </LI> <LI> Microalgae were tolerant to HC, and thus HC provides a selective method. </LI> <LI> Energy consumption of HC was the lowest among the physical methods. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Antioxidant and Cytoprotective Effects of (−)-Epigallocatechin-3-(3″-O-methyl) Gallate
Kim, Eunji,Han, Sang Yun,Hwang, Kyeonghwan,Kim, Donghyun,Kim, Eun-Mi,Hossain, Mohammad Amjad,Kim, Jong-Hoon,Cho, Jae Youl MDPI AG 2019 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.20 No.16
<P>Reactive oxygen species (ROS) are generated from diverse cellular processes or external sources such as chemicals, pollutants, or ultraviolet (UV) irradiation. Accumulation of radicals causes cell damage that can result in degenerative diseases. Antioxidants remove radicals by eliminating unpaired electrons from other molecules. In skin health, antioxidants are essential to protect cells from the environment and prevent skin aging. (−)-Epigallocatechin-3-(3″-O-methyl) gallate (3″Me-EGCG) has been found in limited oolong teas or green teas with distinctive methylated form, but its precise activities have not been fully elucidated. In this study, we examined the antioxidant roles of 3″Me-EGCG in keratinocytes (HaCaT cells). 3″Me-EGCG showed scavenging effects in cell and cell-free systems. Under H2O2 exposure, 3″Me-EGCG recovered cell viability and increased the expression of heme oxygenase 1 (HO-1). Under ultraviolet B (UVB) and sodium nitroprusside (SNP) exposure, 3″Me-EGCG protected keratinocytes and regulated the survival protein AKT1. By regulating the AKT1/NF-κB pathway, 3″Me-EGCG augmented cell survival and proliferation in HaCaT cells. These results indicate that 3″Me-EGCG exhibits antioxidant properties, resulting in cytoprotection against various external stimuli. In conclusion, our findings suggest that 3″Me-EGCG can be used as an ingredient of cosmetic products or health supplements.</P>
DongHyun Kim,SunIl Kim,Mookeun Song,JunHyun Kim,MinGyu Choi,DoYeong Mun,DaeWon Cho 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.2
As the decommissioning of domestic nuclear power plants (Gori Unit 1 and Wolseong Unit 1) becomes more visible, many research projects are being conducted to safely and economically decommissioning of domestic nuclear power plants (NPPs). After permanent shutdown, decommissioning of NNPs proceeds through decontamination, cutting of main equipment, waste disposal and site restoration stages. And various technologies are applied at each stage. In particular, remote cutting of neutron induced structures (RV, RVI, etc.) is a technology used in developed countries in the cutting stage, and remote cutting has been evaluated as a core technology for minimizing workers’ radiation exposure. Generally, remote cutting technologies are divided into mechanical/thermal/electrical cutting. Among various thermal cutting technologies, plasma arc cutting (PAC) is more economical and easily to remote control than other cutting technologies, and is also effective in cutting STS304 plates. PAC is a thermal cutting technology that melts the base material at the cutting area with a plasma arc heat source and removes melted material by blowing it out with cutting gas. The cutting quality depends on the stand-off distance and power (current), material thickness, cutting speed, etc., while double arcing will occur if the cutting conditions are not suitable. A monitoring system that can confirm double arcing during remote cutting is necessary because double arcing can reduce cutting quality, increase secondary waste (increase kerf and aerosol), and cause non-cutting. In this study, we used an ultrahigh-speed camera equipped with a band-pass filter to capture clear arc shapes, and measured voltage waveforms with a data acquisition system. We studied a monitoring method that can confirm the occurrence of double arcing by synchronizing the obtained arc shape and voltage waveform, and the effects of double arcing on the STS304 plates. The results of this study are expected to be helpful in the development of the remote cutting process using plasma arc cutting when decommissioning of domestic NPPs.
Kim Donghyun,서을주,송윤선,Suh Chong Hyun,Kim Jong Won,Kim Dong Joon,서대철 대한신경중재치료의학회 2019 Neurointervention Vol.14 No.2
Purpose: Hereditary hemorrhagic telangiectasia (HHT), a rare genetic vascular disorder, has been rarely reported in South Korea. We investigated the current prevalence and presenting patterns of genetically confirmed HHT in South Korea. Materials and Methods: We defined HHT patients as those with proven mutations on known HHT-related genes (ENG, ACVRL1, SMAD4, and GDF2) or those fulfilling 3 or 4 of the Curaçao criteria. A computerized systematic search was performed in PubMed and KoreaMed using the following search term: (“hereditary hemorrhagic telangiectasia” AND “Korea”) OR (“Osler-Weber-Rendu” AND “Korea”). We also collected government health insurance data. HHT genetic testing results were collected from three tertiary hospitals in which the genetic tests were performed. We integrated patient data by analyzing each case to obtain the prevalence and presenting pattern of HHT in South Korea. Results: We extracted 90 cases from 52 relevant articles from PubMed and KoreaMed. An additional 22 cases were identified from the three Korean tertiary hospitals after excluding seven cases that overlapped with those in the published articles. Finally, 112 HHT patients were identified (41 males and 71 females, aged 4–82 years [mean±standard deviation, 45.3±20.6 years]). The prevalence of HHT in South Korea is about 1 in 500,000, with an almost equal prevalence among men and women. Forty-nine patients underwent genetic testing, of whom 28 had HHT1 (ENG mutation) and 19 had HHT2 (ACVRL1 mutation); the other two patients were negative for ENG, ACVRL1, and SMAD4 mutations. Conclusion: The prevalence of HHT is underestimated in Korea. The rate of phenotypic presentation seems to be similar to that found worldwide. Korean health insurance coverage is limited to representative genetic analysis to detect ENG and ACVRL1 mutations. Further genetic analyses to detect HHT3, HHT4, and other forms of HHT should be implemented.