혈관질환 정보관리 시스템

김동익,김덕경,허세호,이병붕,김용신,김은숙,문지영,도영수,신성욱,김동수,김만태,진재욱,김용신 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1

As medical technology progresses rapidly, there is a rise in the average age along with the Korean dietary lifestyle becoming more westernized, which leads to an increase in the number of vascular disease patients in Korea. Thus, we need to manage the medical information of a disease systematically in order to diagnose and treat constructively. However, since there has been no standardized method of man agement to date, a great deal of information could not be properly utilized nor studied. Therefore, the departments of Cardiology, Radiology and Neurology of Samsung Seoul Hospital recently got together to develop an information management system called the Vascular Data System. This program was developed to be run on win98 O/S, upper Pentium Ⅲ, and upper 128 MB Memory, and its source code is Dephi 4.0. It was configured for the user to set the configurations as well as do a variety of search and analysis. If this program were to be updated continuously, it may be used extensively as well as in various parts of clinical research activities.

韓國河川의 流出率과 流出指標로서의 洪水直前 流量

金熙鍾,柳又秀,金佳鉉,申東守,韓健模,全裕燦 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-

This paper is a study on relation between run-off ratio and antecedent discharge, run-off ratio and antecedent discharge per unit area, antecedent discharge and antecedent precipitation, by the data from the five major river basins in Korea and the small river basins in Pusan. The Nak-Dong rivers(An-Dong upper stream) f=0.4780+0.0124 ln qA r=0.99 qA=0.3368e0.1101R r=0.99 f=0.5793+0.0146 ln(qA/A) r=0.99 The Nak-Dong rivers except Ga-song station f=0.2017-0.0840 ln qA r=0.75 f=0.7012+0.0750 ln(aA/A) r=0.71 The Han rivers f=-0.0035+01267 on qA r=0.75 f=1.1311+0.1263 ln(qA/A) r=0.71 L=302.9064-43.8490 ln qA r=0.84 The Geun rivers(Mu-sin Cheon) f=0.295+0.1823 ln qA r=0.93 f=0.8417+0.1823 ln(qA/A) r=0.93 L=40.0456+62.0346 ln qA r=0.94 The Yeong-san rivers f=0.3766+0.0598 ln qA r=0.79 f=0.8084+0.0599 ln(qA/A) r=0.79 The Seom-jin rivers f=-1.3875+0.6505 ln qA r=0.92 f=2.1633+0.3465 ln(qA/A) r=0.76 Small river basin in Pusan f=0.3635+0.1120 ln qA r=0.87

우리나라에서 솔껍질깍지벌레의 분포확산

임유진,이상명,김동수,김준범,최광식,이신혜,박정규,이동운,Lim, Eu-Gene,Lee, Sang-Myeong,Kim, Dong-Soo,Kim, Joon-Bum,Lee, Shin-Hye,Choi, Kwang-Sik,Park, Chung-Gyoo,Lee, Dong-Woon 한국응용곤충학회 2012 한국응용곤충학회지 Vol.51 No.1

솔껍질깍지벌레는 우리나라 곰솔림의 주요한 해충의 하나이다. 본 연구는 우리나라에서 솔껍질깍지벌레의 분포를 알아보기 위하여 7개도 3개 광역시, 91개 시군구, 686 읍면동의 해송림에서 2010년 밀도를 조사하였다. 5개도 2개 광역시에서 솔껍질깍지벌레가 서식하고 있었는데 시군구별로는 조사대상의 64.8%인 59개 시군구에서 서식이 확인되었다. 솔껍질깍지벌레의 분포는 남해안 전역과 동해안의 포항, 서해안의 충남 보령지역까지 분포하였다. 충북과 대전광역시 및 제주도에서는 솔껍질깍지벌레의 분포가 확인되지 않았다. 부산지역은 16곳의 모든 구에서 솔껍질깍지벌레가 분포하였고, 시군 단위에서는 전남 해남군의 솔껍질깍지벌레 평균밀도가 1.713마리/0.785 $cm^2$로 가장 높았으며 읍면동 단위에서는 해남군 송지면이 6.36마리/0.785 $cm^2$로 가장 높았다. 곰솔 가지 내의 솔껍질깍지벌레 밀도와 솔껍질깍지벌레가 서식하고 있는 빈도와는 높은 상관관계가 있었다(상관계수=0.89). The black pine bast scale, $Masucoccus$ $thunbergianae$ (Hemiptera: Margarodidae), is a serious pest of the Japanese black pine, $Pinus$ $thunbergii$, in Korea. The distribution of the black pine bast scale was examined, looking overall at 686 towns (eup), townships (myeon) or neighborhoods (dong). There were Japanese black pine ($Pinus$ $thunbergii$) forests in 91 cities, counties (gun) and borough (gu), in seven provinces and three metropolitan cities during 2010. Black pine bast scale were found in 64.8% of cities or counties or borough (59) in 7 provinces and 3 metropolitan cities, and were distributed in all South Costal regions, Pohang in East Costal region and Boryeong in West Costal region. Chungcheongbukdo, Daejeon and Jeju did not have black pine bast scale. All the gu regions in Busan had black pine bast scale, of which the area with the highest prevalence was Haenam in Jeollanamdo (1.713 crawlers/0.785 $cm^2$). Songji-myeon had the highest occurrence rate (6.36 crawlers/0.785 $cm^2$) from the towns, township and dong. The density of black pine bast scale in twigs was highly correlated with percentage of the sample with scale (Correlation coefficacy=0.89).

Farnesol의 合成

申東守,安志英,金美羅 國立昌原大學校 基礎科學硏究所 1992 基礎科學硏究所論文集 Vol.3 No.-

5-Bromo-methypent-2-ene(??)를 출발물질로하여 farnesol인(2E, 6E)-3, 7, 11-trimethyldodeca-2, 6, 10-trien-1-ol(??)의 입체선택적 합성을 수행하였다. 5-Bomo-2-methylpent-2-ene (??)을 요오드화 시킨후, 5-lithio-2, 3-dihydrofuran과 반응시켜 5-(4-methyl-pent-3-enyl)-2, 3-dihydrofuran(??)을 얻었다. Dihydrofuran ??를 MeMgI와 Ni(0)-촉매 짝지음 반응시켜 (3E)-4, 8-dimethylnona-3, 7-dien-1-ol(??)을 72%의 수율로 얻었다. 알릴알코올 ??를 4단계를 거쳐 (5E)-6, 10-dimethylundeca-5, 9-dien-2-One(??)으로 변환시켰다. 화합물 ??을 벤젠 용매하에서 dimethylmethoxycarbonylmethylphosphonate와 반응시킨 다음, 에탄올 용매하에서 NaBH₄ 환원시켜서 (2E, 6E)-3, 7, 11-trimethyldodeca-2, 6, 10- trien- 1- ol(??)을 얻었다. Dihydrofuran 4와 MeMgI와의 Ni(0)-촉매 짝지음반웅이 본 연구의 farnsol(??)와 합성에서 중요 단계이다. Stereoselective synthesis of farnesol (2E, 6E) -3, 7, 11-trimethyldodeca-2, 6, 10-tiren-1-o1 (?) , was carried out using 5- bromo-2-methylpent-2-ene (??) as a starting material. After conversion of 5-bromo-2-methyl-pent-2-ene (2) to the corresponding iodide compound, 5-(4-methylpent-3-enyl)-2, 3-dihydrofuran(??) was obtained by alkylation of 5-lithio-2, 3-dihydrofuran with 5-iodo-2-methylpent-2-ene. Ni(0)-catalyzed coupling reaction of the dihydrofuran ?? with MeMgI was proceeded to give (3E)-4, 8-dimethylnona-3, 7-dien-1-ol(??) in 72% yield. The resultant homoallylic alcohol ?? was converted to the (5E)-6, 10-dimethylundeca-5, 9-dien-2-one (??) in 4 steps. Compound 8 was condensed with dimethylmethoxycarbnylmethylphosponate in benzene followed by NaBH₄reduction in EtOH to yield (2E, 6E)-3, 7, 11 -trimethyldodeca-2, 6, 10-trien-1-ol(??), Ni(0)-catalyzed coupling reaction of MeMgI with dihydrofuran ?? was a key step in this synthesis of farnesol(??).

모성 직업활동이 조산과 저체중출생 및 자연유산에 미치는 영향

신용덕,이태용,이영수,이동배 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.1

모성 직업활동이 조산, 저체중 출생아 및 자연유산에 미치는 영향을 알아보기 위해 1991년 1월부터 1992년 12월까지 대전에 위치한 C대학병원에서 출생한 1,646명의 산모를 대상으로 하여 조사한 결과는 다음과 같다. 1. 조사 대상자 1,646명의 산모중 임신중 직업을 가진 군이 20.3%, 직업을 갖지않은 군이 79.7%였으며, 직업여부의 분포에 통계적으로 유의한 차이를 보인 변수는 산모의 연령, 교육정도, 임신전 체중, 신장, 유산횟수였다. 2. 임신중 직업을 가진군의 평균 임신기관과 조산율은 39.1주, 7.8%였고, 비직업군은 39.0주, 9.7%였다. 직업군에서 평균 출산아 체중과 저체중 출생아율은 3.228g, 5.4%였고 비직업군은 3,140g, 10.6%였으며, 통계적으로 유의한 차이를 보였다(p<0.05). 평균 자연유산 횟수와 자연유산 경험율은 직업군이 0.2회, 15.0%, 비직업군이 0.3회, 17.4%였다. 3. 연령이 35세 이상, 미숙아 출산력이 있는 경우 및 유산횟수가 2회 이상인 경우는 직업군의 조산율과 저체중 출생아율이 비직업군에 비해 높았으나 통계적 유의성은 없었다. 산과적 합병증이 없는 경우 조산율이 직업군에서 비직업군보다 높았으나 역시 통계적 유의성은 없었다. 4. 자연유산 경험률은 연령이 35세 이상, 학력이 중졸 이하 및 고졸, 산모의 신장이 163cm이상에서 직업군에서 비직업군보다 높게 나타났으나, 통계적 유의성은 없었다. 5. 조산과 관련성이 있는 요인의 영향을 고려했을 때 직장활동군에서 조산의 위험도가 낮았으나 통계적 유의성은 없었다. 6. 임신주수 및 저체중 출생에 관련이 있는 요인의 영향을 고려한 후 직업군에서 저체중 출산의 위험도가 낮았으며 통계적 유의성을 보였다(p<0.05). 7. 과거 유산에 관련이 있는 요인의 영향을 고려한 경우 직업군에서 유산경험율이 낮았으나 통계적 유의성은 없었다. 8. 직업이 교사, 의료인, 은행원, 공무원인 군은 비직업군보다 조산율과 저체중 출생아율이 낮았으며, 회사원은 비직업군에 비해 조산율은 낮았으나 저체중 출생아율은 높았다. 상업군은 조산율과 저체중 출생아율이 15.2%로 비직업군 및 다른 직업군보다 비교적 높았다. 유산경험율은 은행원, 의료인,공무원에서는 비직업군의 17.0%보다 낮았으나, 교사군과 회사원은 17.8, 17.9%로 높았고, 상업군은 33.3%로 다른 직업군에 비해 현저히 높았으며 비직업군에 비해 교차비가 1.42로 통계적 유의성이 있었다(p<0.05). To investigate the effect of maternal job activity on the preterm delivery, low birth weight infant and spontaneous abortion, 1646 delivery data were analyzed from Jan. 1991 to Dec. 1992 in Chungnam University Hospital. The results obtained were as follows; 1. The percentage of subjects who had job during pregnancy was 20.3% and the variables of maternal age, education level, prepregnancy weight, maternal height, number of abotion showed significant difference in the distribution of subjects whether they had job or not. 2. There were no significant difference between the group who had job during pregnancy and those who had no job in the mean gestational period, number of spontaneous abortion, rate of preterm delivery and spontaneous abortion. However mean birth weight and rate of low birth weight showed significant difference between the groups. 3. The rate of preterm delivery of the group who had job were higher than those who had no job activity in the subgroup of 35 years or more age, prematurity history presence, 2 or more abortion history, obstetric complication presence, but there were no significant difference. The rate of low birth weight also higher in the group who had job than those who had no job activity in the same subgroup except obstetric complication presence. 4. The rate of spontaneous abortion of the group who had job were higher than those who had no job activity in the subgroup of 35 years or more age, below high school, height of 163cm or above, but there were no significant difference. 5. Rate of preterm delivery still showed better results in the group who had job than the group who had no job when adjusted for variables related, but there was no statistical significance. 6. Rate of low birth weight still showed better results with statistical significance in the group who had job than the group who had no job when adjusted for variables related. 7. Spontaneous abortion had occured less frequently in the group who had job than the group who had no job when adjusted for variables related. 8. Rate of preterm delivery and low birth weight were lower in the group of teacher, bank clerk, medical personnel, citizen servant than the group who had no job, but higher in the job of company employee, commerce. Spontaneous abortion was most frequent in group of commerce, and the group of teacher, company employee showed higher rate of abortion than the group who had no job.

세기변조방사선치료의 선량분포 검증에 관한 연구

권수일,신동호,송재영,안진호 京機大學校 2006 論文集 Vol.50 No.-

Film dosimetry as a part of patient specific intensity modulated radiation therapy quality assurance (IMRT QA) has been accomplished to develop the new optimization method of film isocenter offset and to suggest the new quantitative criteria for film doimetry after optimization. Five patients with head and neck cancers were measured in IMRT dosimetry by film method. Optimization method with the local minimum was developed to adjust the film isocenter offset error, which is the biggest part of systemic errors. The mean ratios were 5.33% and 7.09% for 5mm and 1 mm resolution dose data optimization respectively.

광섬유 집합체 센서를 이용한 6MV 광자선의 반음영 및 심부선량백분율 측정

신상훈,장경원,조동현,유욱재,서정기,이봉수,문주현,박병기 제주대학교 방사선응용과학연구소 2008 방사선응용과학연구소논문집 Vol.22 No.-

In this study, a fiber-optic bundle sensor has been developed using water-equivalent organic scintillating fibers for photon beam measurement. Beam penumbra and percent depth doses(PDD) are measured according to the depth of the photon beam. This sensor has many advantages such as high resolution, real-time measurement and ease of calibration over conventional radiation measurement devices.

集團的으로 發生한 S. typhimurium에 對하여

申東秀,金在煥 경북대학교 의학연구소 1969 慶北醫大誌 Vol.10 No.2

Author performed microbiological studies on salmonella typhimurium isolated from food poisoning among the employee of university Hospital on Spring, 1968. The results were as follows; 1. Among 78 cases of food poisoning 31 strains of salmonella typhimirium were isolated. 2. The strains were identified by means of serological and biochemical reactions as typical salmonella typhimurium. 3. The sensityvity patterns of the isolated salmonella typhimurium were highly sensitive to chlorampenicol, terramycin, albamycin, kanamycin, streptomycin, sigmamycin and nitrofurantion, and resistant to penicilline, bacitracin, achromycim, erythronycin and oleandomycin. 4. Under the suspicion of pork contamination author tried to isolate the causatie organism of pork from seller, also examined to detect the carriers from employee handled the pork, however, both results were not contributive.

경통 및 요통 환자에서 세라젬 마스터 온열 치료기의 효과

신동배,이영수,전중선,김성원,강형곤 최신의학사 2000 最新醫學 Vol.43 No.9-10

방사선조사 후 타액선 세포와 혈관 내피세포의 DNA합성에 관한 면역조직학적 연구

신종섭,유동수 大韓口腔顎顔面 放射線學會 1991 Imaging Science in Dentistry Vol.21 No.2

After single fraction of 2,5,10 Gy irradiation on submandibular gland of 40 male rats, weighing 150gm, respectively, these animal were sacrificed two hours after 0.1 mg/g bromodeoxyuridine(Sigma) peritoneal injection in 1,3,7,15 hours, 1,3,7, days after irradiation. And excised submandibular gland were fixed in Carnoy' and Bouin's solution for 2 hours. Paraffin sections were stained with H&E, and PAS for the observation of the change of salivary gland tissue, and with Feulgen for the study of the DNA distribution, and immunohistochemically stained with anti-bromodeoxyuridine (Sanbyo Co.) for detection of DNA synthetic cells in order to study the distribution of DNA synthetic cells of salivary gland tissue and endothelium after irradiation in 5 different sites of 6 slides on X 200 high power field. The results were as following. 1. In PAS staining 3 days after 5Gy irradiation, decreased mucine secretion of serous cells were found, and 7 days after 10 Gy irradiation, decreased mucine secretion of mucous cells were found. 2. In histopathologic features, degeneration of serous cells were found in 3 days after 2 Gy irradiation and there was little change in mucous cells and excretory duct cells. 3. In Feugen staining, 3 days after 2 Gy, 5 Gy irradiation, more high percentage of DNA synthetic cells were found in intercalated duct cells, striated duct cells and excretory duct cells than in BrdU staing. 4. In immunohistochemical features, DNA synethsis of serous cells and granular convoluted tubular cells abruptly decreased in early period after irradiation and showed no recovery in 7 days after irradiation but there was an increase in DNA synthesis of intercalated duct cells, striated duct cells and excretory duct cells, which have less S-phase cells comparatively, in 7 days after 2 Gy, 5 Gy irradiation. 5. In immunohistochemical features, the DNA synthesis of endothelial cell was continuously decreased after irradiation but showed slight increase in 7 days after 2 Gy and 5 Gy irradiation.