표면 비드높이 예측을 위한 최적의 신경회로망 선정에 관한 연구

손준식,김인주,김일수,장경천,이동길 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

The full automation of welding has not yet been achieved partly because the mathematical model for the process parameters of a given welding task is not fully understood and quantified. Several mathematical models to control welding quality, productivity, microstructure and weld properties in arc welding processes have been studied. However, it is not an easy task to apply them to the various practical situations because the relationship between the process parameters and the bead geometry is non-linear and also they are usually dependent on the specific experimental results. Practically, it is difficult, but important to know how to establish a mathematical model that can predict the result of the actual welding process and how to select the optimum welding condition under a certain constraint. In this paper, an attempt has been made to develop an neural network model to predict the weld top-bead height as a function of key process parameters in the welding. and to compare the developed model and a simple neural network model using two different training algorithms in order to select an optimal neural network model.

주사 탐침 현미경을 이용하여 표면 처리한 기판 위의 DNA 관찰

이남주,손정민,진상협,전동렬,강치중 명지대학교 자연과학연구소 2004 자연과학논문집 Vol.23 No.-

대장균에서 추출한 plasmid DNA를 운모 기판에 착상시켜 주사 탐침 현미경으로 관찰하였다. plasmid DNA를 운모 기판에 착상시키기 위하여 운모 기판을 염 이온으로 0.01~10mM까지 농도를 변화시켜 표면 처리하였다. 운모 기판 위 염 이온의 농도 차이를 X-선 광전 분광기(XPS)로 표면을 분석하였다. 기판 처리에 사용한 염 이온의 농도에 영향을 받아 착상된 DNA의 밀도 및 모양이 변화하였다. 운모 기판 처리 농도에 따른 AFM 영상 차이와 XPS로 분석한 기판 위의 염 이온의 상태를 제시하고, 이들 사이의 상관관계에 대하여 논의하였다. The plasmid DNA on mica is observed using scanning probe microscopy. The mica surface is treated by 0.01~10mM NiCl_(2) for depositing the plasmid DNA. Concentration difference of NiCl_(2) on mica is analyzed a treated mica surface using XPS. The plasmid DNA on the treated mica has a difference of density and conformation in proportion as Ni^(2+) concentration. We present AFM topology difference and Ni^(2+) states on mica by XPS, discuss interaction between AFM topology difference and Ni^(2+) states on mica

Electrostatic Force Microscopy Plasmid DNA의 전기적 특성 관찰

이남주,손정민,진상협,전동렬,강치중 명지대학교 자연과학연구소 2004 자연과학논문집 Vol.23 No.-

p53HIS plasmid DNA를 운모 기판에 착상시켜 기판과 DNA 사이의 전기적인 특성을 electrostatic force microscope(EFM)와 atomic force microscope(AFM)을 이용하여 관찰하였다. DNA를 운모 기판 위에 착상시키기 위해 표면을 NiCl_(2) 용액으로 염 이온 처리했다. 염 이온의 농도에 따라 DNA와 기판과의 상호 작용에 의해 착상량과 DNA 단차 및 EFM 신호(DNA 외관상 단차)에 차이가 있었다. 즉, 염 농도가 높을수록 운모 기판에 고정되어 있는 DNA양이 많아졌고 기판과의 강한 상호 작용에 의해 DNA의 높이가 낮아지는 것을 관찰할 수 있었다. 반면 EFM신호는 탐침과 기판간의 척력 증가에 의해 증가하는 경향을 보였다. 또한 DNA의 한 부분에 전기적인 스트레스를 주었을 때의 특성을 EFM을 이용하여 분석하였다. We observe electrical characteristics between the plasmid DNA and mica by electrostatic force microscopy (EFM) and atomic force microscope (AFM). Firstly, we treated the mica by NiCl_(2) solution for depositing DNA. We monitored density of DNA molecules, DNA height and EFM signal from DNA-substrate interaction as Ni^(2+) concentration. We observe the plasmid DNA's height as Ni^(2+)concentration using AFM. On the other hand, EFM signal increase by increased repulsion between probe and substrate. After introducing voltage stress to a local area of DNA molecule, apparent height difference of DNA molecules was measured due to the charge injection or removal. Similar experiments were done with different bias polarities and sequential stress steps.

全北任實方言 硏究

金海正,孫周一,李氣銅 又石大學校 1982 論文集 Vol.4 No.-

Through collecting some basic dialects in Im-sil district, we are going to find their characteristics in phonology, syntax, and lexicography. We've collected and investigated about 720 lexical items. The investigation method we adopted is the direct question & answer between investigators and informants. Our informants' average age is over sixty, and they have lived there all their lives. The results are as follows; 1. Phonology. A. Their phonological system is found to be almost similar to that of central dialects. We can confirm their vowel system is composed of ten vowels, distinguishing /e/ from /ε/. This phenomenon is different from our common knowledge about it. B. Every single vowel alternates actively in all the vowels. The alternative phenomena between /e/ and /ε/ occur in accordance with back vowel and umlaut respectively. C. Their umlaut phenomena are extensive and similar to those of both central and kyoung-sang dialects. D. Diphthongs with consonant in the initial syllable usually alternates with single vowel. E. We find their palatalization more various than that of central dialects. This phenomena are sure to occur when the condition is given in the first and second syllable. F. Glottalized phenomenon is more productive than aspirated phenomenon. Ⅱ. Syntax. A. The form" -(h??) d??e" is the predicate of matrix sentence which dominates the complementrary structure. B. The form "-jad??i" has a [+Active] as syntactic property while the forms "-d??i" and "d??e" don't C. The forms "a/??rau" and "-d??irau" can be integrated with the form "-ja d??i" but can't be integrated with the form "(h??) d??e" naturally. D. The form "-d??i" is pronounced with rising intonation and assumed to be tag-question usage for the moment. D. While the form "-d??i" with explanatory final ending is used as a Korean general form as a converbum, the form "-jad??e" isn't. F. The purpose of this paper is to point out the general fallacy of classifying the form "-had??i" and "-had??e" as a traditional distinctive features of dialect form (allomorph) in Im-sil dialect, when collecting data of dialect syntax with a special criteria. Ⅲ. Lexicology. Aiming to establish lexical system of subdialect, lexical category is limited within a scope of semantic method and posture. We investigate it with pure and unconfused semantic approach. We describe them synchronically; the meanings of Im-sil dialects based on informents' detailed expressions. We contrast them with standard language. Any particular expression, if necessary, is selectively accounted in the main body.

고도정수처리 공정에서의 천연유기물질 특성변화 및 소독부산물 전구물질의 제거특성 평가

노재순,손희종,박은주,황영도,최동훈,배석문,신판세 慶星大學校 環境問題硏究所 2002 環境硏報 Vol.12 No.1

In this research the movement and apparent molecular weight distribution of hydrophilic/hydrophobic organic matters in advanced water treatment process were investigated using the raw water of Maeri area, located in downstream of Nakdong river, and the variation of the disinfection by-product formation potential was also investigated. In the raw water used in experiments, the content of BDOC (biodegradable dissolved organic carbon) in dissolved organic carbon (DOC) was about 39%, and this value is far above a normal, Pre-ozone treatment showed an increase of 40% in the BDOC content, and this means that biodegradability was remarkably increased by ozone treatment BDOC concentration in BAC treated water was 0.09 mg/L, which means 84% of BDOC removal rate compared with that in post-ozone treated water. The variation of chlorine disinfection by-product formation potential in each process unit of water treatment process was analyzed. TOXFP concentration in raw water was 449 ㎍/L, and the contents of THMFP and HAAFP among TOXFP were 24% and 23%, respectively. The removabilities of these materials BAC process had an order of TOXFP > HAAFP > THMFP. BAC process was less effective for THMFP than others. The distribution of hydrophilic organic matters were evaluated in each treatment process. Hydrophilic and hydrophobic matters in the raw water had a ratio of 50 : 50, and the ozone treatment decreased the content of hydrophobic matters. The BAC treatment made the ratio 85:15. These mean that the removal of hydrophilic matters is more difficult than that of hydrophobic materials in water treatment process. In addition the portions of humic and fulvic acid in hydrophobic matters were analyzed. Fulvic acid a large portion among hydrophobic matters in the raw water, and the portion was 78%. Ozone treatment was more effective on the removal of fulvic acid than humic acid. After BAC treatment, the concentration of residual fulvic acid was high than humic acid. Chlorine disinfection by-product formation for hydrophilic and hydrophobic mattrts was compared in each process unit. in the raw water TOXFP and THMFP formation for hydrophobic matter was higher, and HAAFP was highly formated for hydrophobic matter. After post-ozone or BAC treatment, chlorine disinfection by-product formation has high potential for hydrophobic matters. Comparing humic and fulvic acids, chlorine disinfection by-product formation potential was higher for humic acid than for fulvic acid in all processes. In the comparison of the reactivity with chlorine disinfection by-product per unit DOC, THMFP and DOXFP showed higher reactivity with hydrophobic matter than with hydrophilic matter in all processes, and HAAFP was highly reacitive with hydrophilic matter. Apparent molecular weight distributions of organic matters were investigated in each process step.The content of low molecular weight organic matters less than 1000 Da in DOC was high in all processes except raw water, but molecular weight organic matters more than 1000 da was higher than molecular weight organic matters less than 1000 Da in the formation potential of chlorine disinfection by-product.

性別 및 年齡에 따른 體格과 體力의 特性과 變化에 關한 縱斷的 硏究Ⅱ : Emphasised on College Men of Department of Physical Education 體育專功 大學生을 中心으로

金尙國,姜東洹,張周鎬,金昇一,徐再均,金耕知,孫斗玉,鮮于攝,崔榮烈,尹宇相,金亨燉,方永鎭,朴英震,柳在忠 慶熙大學校 體育科學大學 1989 體育科學論叢 Vol.- No.2

The purpose of this study was to compare the characteristics, change in physique and physical function of college students majoring physical education and Taekwondo (454 males and 64 females of age groups ranging from 18 to 26). The results are as following: 1. The male group of 23yrs old in physical education showed highest values in 7 items(Weight, Chest Girth, Fore Arm Girth, Thigh Girth, Calf Girth, Scapular Skinfold Thickness and Suprailiac Skinfold Thickness). 2. In the Physical function, the male group of 18yrs old showed highest values in Power, Flexibility, and then 21yrs old at Back Strength, Vital Capacity, and 23yrs old at Grip Strength, and 25yrs old at Blood Pressure, respectively. 3. In the physique, the male group of 22yrs old showed highest values in Weight, Chest Girth, Thigh Girth, Calf Girth, and then 24yrs old Upper Arm Girth, Fore Arm Girth, and 19yrs old at Height, Upper Limb Length, respectively. 4. In Physical Function, the 22yrs old showed highest values in Back Strength, Vital Capacity, and then 23yrs old at Side Step, Trunk Extension, but 18yrs old showed lower Values in Grip Strength, Side Step, Vital Capacity and Blood Pressure. 5. The female group of 22yrs old showed highest values in 8 items(Height, Sitting Height, Waist Girth, Upper Limb Length, Lower Limb Length, Skinfold Thickness), and then 18yrs old at 5 items (Weight, Upper Arm Girth, Fore Arm Girth, Thigh Girth, Calf Girth), respectively. 6. In the physical function, the 22yrs old showed highest Values in Grip strength, Back Strength, Power, 5 Minute Run, and 18yrs old at flexibility, Harvard Step Test, respectively. 7. In the change of the physique for two years(1988-1989) in the male group, majoring Physical education the 22yrs old showed increase in 4 items, and the 20yrs old in 3 items, but 18yrs old showed decrease in 3 items. 8. In the change of the physical function for two years in the male group, the 20yrs old showed increase in 4 items, and the 21, 25, 26yrs old in 3 items, but the 19yrs old showed decrease in 6 items, and 18, 22 yrs old in 5 items, respectively. 9. The change of the physique for two years in all female group, of 18, 19, 20, 21yrs old showed increase in 11 items except Skinfold Thickness. 10. In the change of physical function for two years in female group, the 18yrs old showed increase in 3 items, and then 20yrs old in 5 items, but 19, 22yrs old decreased 12 items, respectively. 11. The highest significant difference in physique between male and female was found in weight(mean Value 17.5%), and the lowest difference was found Thigh Girth, Calf Girth(1,3%), Upper Limb Length, Lower Limb Length(2.5%). 12. The Highest difference in physical function was Strength (mean Value 40%), Vital Capacity (33%), Power(22%), but Lower Trunk Flexion, Foot Balance(3.4%). 13. In the difference of Physique and physical function between physical education major and taekwondo major, the physical education showed higher values in skinfold Thickines (mean Value 16.5%), Weight, Waist Girth(4.7%) and Strength(33%), Endurance(5.6%), but subjects majoring Taekwondo showed higher values in Flexibility and Foot Balance. 14. In all male groups, Waist Girth, Scapular Skinfold Thickness, Back Strength, Sargent Jump, Trunk Extension and Diastolic Blood Pressure were showed a significantly related at 0.001 level.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

Inhibitory Effects of Taheebo (Tabebuia impetiginosa Martius ex DC.) on Platelet Aggregation and Aortic Vascular Smooth Muscle Cell Proliferation

Son Dong-Ju,Lim Yong,Park Young-Hyun,Yun Yeo-Pyo,Lee Sung-Eun,Park Byeoung-Soo 대한약학회 2004 大韓藥學會 總會 및 學術大會 Vol.2004 No.1

Melittin, A Major Bioactive Component of Bee Venom Toxin, Inhibits PDGF Receptor Beta-tyrosine Phosphorylation and Downstream Intracellular Signal Transduction in Rat Aortic Vascular Smooth Muscle Cells

Son, Dong Ju,Kang, Jun,Kim, Tack Joong,Song, Ho-Sueb,Sung, Ki-Joong,Yun, Do Young,Hong, Jin Tae TAYLOR & FRANCIS 2007 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH PAR Vol.70 No.15-16

<P> Studies previously reported that melittin, a major bioactive component of bee venom, inhibits vascular smooth muscle cell (VSMC) proliferation through suppression of nuclear factor (NF)-&kgr;B and Akt activation and through enhancement of proapoptotic protein expression. In this study, the effects of melittin were investigated on the tyrosine phosphorylation of platelet-derived growth factor (PDGF) beta receptor (R&bgr;) and its downstream intracellular signal transduction. When combined with PDGF-R&bgr; inhibitor, melittin exhibited a synergic inhibitory effect on PDGF-BB-induced rat aortic VSMC proliferation. In addition, melittin inhibited PDGF-R&bgr; phosphorylation in a concentration-dependent manner. Accordingly, the downstream signal transduction of PDGF-R&bgr;, such as ERK1/2, Akt, and PLC&ggr;1 phosphorylation, was also inhibited by melittin in the same manner. These findings suggest that, in addition to suppressing NF-&kgr;B activation, the antiproliferative effect of melittin in VSMC may be mediated, at least in part, by the inhibition of PDGF-R&bgr; tyrosine phosphorylation and its downstream intracellular signal transduction.</P>

Inhibitory Effect of Melittin on the Vascular Smooth Muscle Cell Proliferation

Hong Jin Tae,Yun Yeo Pyo,Moon Dong Cheul,Lee Seung Ho,Lim Yong,Son Dong Ju 대한약학회 2004 大韓藥學會 總會 및 學術大會 Vol.2004 No.2