담낭종양에서 CD24의 역할

임성철,이용,김동출,강길,변익건,박정희,최석민 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

CD24 is a small heavily glycosylated glycosylphosphatidylinosito-linked cell surface protein, which is expressed in hematologic malignancies as well as in a large variety of solid tumors, It appears to function as a ligand of PUselectin, an adhesion molecule that is present in activated platelets and endothelial cells. The authors aimed to evaluate CD24 protein expression in adenoma and adenocarcinoma of gallbladder to correlate to clinicopathologic data. The staining- was evaluated as stainability (negative, weak-, moderate-, strong-positive) and staining' patterns (membranous vs. intracytoplasmic) for statistical analysis. A highly significant association of cytoplasmic CD24 expression with adenocarcinoma compared to the adenoma of gallbladder was demonstrated. The present study demonstrates that CD24 was abundantly expressed on adenocarcinoma rather than on adenoma, but it was not statistically significant, Interrelation between the stainability or intracytoplasmic staining of CD24 and lymph node metastasis was not statistically significant. The authors conclude that CD24 is involved in tumorigenesis of gallbladder mucosa and intracytoplasmic expression of CD24 is an important molecular marker for malignant transformation.

칼슘제 수관살포가 참다래의 과실 품질과 저장에 미치는 영향

임경호,나양기,임동근,마경철,조윤섭,김월수,이상현,박용서 全南大學校 農業科學技術硏究所 2001 農業科學技術硏究 Vol.36 No.-

This study were carried out to improve Kiwifruit quality and storage life. Three kinds of calcium compound were sprayed and calcium content of fruits, weight loss during fruit storage and fruit quality were investigated. Calcium contents within leaves and fruit were lower in Clef-non treatment than that of control. The calcium content in fruit pericarp of Kalk-H and CaCl2 was 0.04 to 0.05% higher than that of control. Fruit weight and soluble solids content at harvest was a little higher but acidity and fruit hardness was lowered. Fruit weight loss of Kalk-H and CaCl2 treatment was 1.39 to 1.53% lower than that of control during storage. The soluble solids of ripen fruit was 1.0 to 1.3% higher in all treatment and 0.8% higher in Kalk-H treatment in 120 of after storage. Fruit hardness of control fruit was higher at harvest but that of CaCl2 treatmented fruit was 0.39㎏/φ 5㎜ higher in 120 days of storage.

강유전체 박막 커패시터 하부전극에 관한 연구

임동건,정세민,최유신,김도영,이준신 성균관대학교 1997 학술회의지원논문목록집 Vol.1997 No.-

We have investigated Pt and RuO₂as a bottom electrode for a device application of PZT thin film. The bottom electrodes were prepared by using an RF magnetron sputtering method. We studied some of the property influencing factors such as substrate temperature, gas flow ratem and RF power. An oxygen partial pressure from 0 to 50% was investigated. The results show that only Ru metal was grown without supplying any ‬O₂gas. Both Ru and RuO₂phases were formed for ‬O₂partial pressure between 10-40%. A pure RuO₂phasewas obtained with ‬O₂partial pressure of 50%. A substrate temperature from room temperature to 400°C was investigated with XRD for the film crystallinity examination. The substrate temperature influenced the surface morphology and the resistivity of Pt and RuO₂ as well as the film crystal structure. From the various considerations, we recommend the substrate temperature of 300°C for the bottom electrode growth. Because PZT film growth on top of bottom electrode requires a temperature process higher than 500°C, bottom electrode properties were investigated as a functiona of post anneal temperature. As post anneal temperature was increasedm the resistibity of Pt and RuO₂was decreased. However, almost no change was observed in resistibity for an anneal temperature higher than 700°C . From the studies on resistivity and surface morphology, we recommend a post anneal temperature less than 600°C.

냉각판을 이용한 반응고 A356합금의 미세조직

임수근,윤병은,장동훈,엄정필,김득규 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

In this study, microstructure, size of primary α, solid fraction and hardness of A356 Al alloy were investigated. Semi-solid A356 alloys were obtained by semi-solid continuous casting apparatus consists of melting furnace, formation apparatus of granular primary α and continuous casting apparatus. Size of primary α and solid fraction were decreased with decreasing temperature, and with increasing volume of cooling water. At the cooling water temperature of 15℃ and cooling water volume of 18.2ℓ/min, the sizes of primary α phases were decreased up to 40㎛, and fraction solid was 0.68.

균일가열법으로 제조한 반용융 A390합금의 미세조직 및 성형성

임수근,윤병은,장동훈,엄정필,김득규 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

Microstructure of hypereutectic Al-17wt.% Si alloy, fabricated by mechanical stirring and by reheating at semi-solid state, was investigated by optical microscope. Flow behavior semi-solid metal also was investigated at diffentent mould temperatures 280℃, 290℃ and 300℃ . Size of silicon particles were increased over 100㎛ durig solidification as a result of stirring. It is considered as microstructural coarsening by bonding between neighbouring primary silicon particles during stirring of slurry. In case of reheating at semi-state, however, primary silicon particle was not increased at size of 40㎛ and nearly spherical aluminum solde particle also was improved when solid fraction was 0.7 at mould temperature of 300℃ than other conditions.

극저사이클 하중을 받는 구상흑연주철의 초기균열성장에 관한 연구

김민건,임복규,김동열 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.A

In this study, extremely low cycle fatigue tests were carried out under push-pull loading conditions using graphite cast iron (GCD). In order to clarify the fatigue fracture mechanism of GCD in an extremely low cycle fatigue regime successive observations of internal fatigue damage were performed. The results obtained are as follows. (1) The process of extremely low cycle fatigue can be classified into three stages which are composed of the generation, growth and coalescence of microvoids inside materials. (2) In an extremely low cycle fatigue regime, microvoids originate from debonding of graphite-matrix interface.

실크 피브로인의 대규모 투석 공정의 단위 모듈의 개발

김동우,하성진,임건빈,허원 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

For the development of a large-scale dialysis process for silk fibroin solution, a batch and continuous dialysis chamber was designed and built, which are to be used as a unit module for the process. A series of dialysis experiments were carried out to estimate the kinetic parameters for dialysis using the solutions of salt-solubilized silk fibroin. The solution was dialyzed by distilled water either batch-wise or continuously. Dialysis kinetics was monitored by measuring refractometery at high salt concentration and conductivity at lower salt concentration. The apparent dialysis coefficients were 5.4g/m2-hr and 1.8g/m2-hr, for well mixed batch and continuous dialysis, respectively. The alteration of molecular weight distribution of dialyzed silk fibroin solution was monitored.

동종 조혈모세포이식 후 발생한 크립토콕쿠스 척추염 1예

고윤호,임동준,이성수,조유경,이동건,최정현,김유진,민창기,김동욱,박정미,김춘추,신완식 대한감염학회 2001 감염 Vol.33 No.4

Skeletal cryptococcosis is an uncommon infection. Cryptococcus is a common cause of meningitis and infects 7∼10% of patients with AIDS. As well as AIDS, the infection may be seen in association with leukemia, lymphoma, Hodgkin's disease, sarcoidosis, tuberculosis and diabetes, also in patients on steroid medication. But there is no case report of skeletal cryptococcosis following allogeneic hematopoietic stem cell transplantation. A 40-year-old woman was admitted to the hospital because of low back pain. She had chronic myelogenous leukemia for 2 years and underwent allogeneic hematopoietic stem cell transplantation 8 months ago. She have been treated with steroid and cyclosporine orally because of chronic graft versus host disease. On examination she was afebrile and had posterior lower lumbar tenderness. But, she had no reduced strength of low extremities. Open biopsy was underwent. Histology demonstrated budding, round-to-oval, refractile yeast-like organisms within debris. The results of a lumbar puncture were unremarkable and cerebrospinal fluid culture failed to grow bacteria and yeast. The patient was treated with amphotericin B (1 gram) and AmBisome□ (2.8 gram) over 6 weeks. Three months after cessation of therapy, the patient was doing well.(Korean J Infect Dis 33:298∼301, 2001)

다결정 실리콘 태양전지의 상부 전극용 금속 박막 적용

김상수,임동건,이준신,심경석,김홍우,이만근 성균관대학교 1997 학술회의지원논문목록집 Vol.1997 No.-

We investigated grain boundary effect for terrestrial applications of solar cells with low cost, large area, and high efficiency. Grain boundaries are known as potential barriers and recombination centers for the photo generated charge carriers, which make it difficult to achieve a high efficiency cell. To reduce these effects of grain boundarues, we investigated various influencing factors such as thermal treatments various grid patterns selective wet etchings for grain boundarues, buried contact metallizations along grain boundaries, and use of metallic thin films. From the various grid patterns we learned that the series resistance of solar cell reduced open circuit voltage and consequently decreased the cell efficiency. This paper describes the effect of various grid patterns and the employment of metallic thin films for a top electrode.

시비방법별 벼 재배에 따른 전과정평가 방법을 적용한 환경영향 평가

신중두,임동규,김건엽,박문희,고문환,엄기철 한국환경농학회 2003 한국환경농학회지 Vol.22 No.1

Consoli가 설명한 것처럼 전과정평가의 개념 및 일반적인 정의에 따르면, 전과정평가는농업생산에 관련된 환경영향을 평가하는데 부합하는 방법이라고 생각되며, 특별히 전과정 평가방법인 Eco-indicator 95는 농업 체재에 대한 환경영향을 분석하는데 적절한 기법인 것으로 입정되었다. Eco-indicator 95 method를 이용하여 지구온난화 및 수계 부영양화와 관련된 시비체계에 따른 벼 재배에 대해 비교할만한 분석체계를 이루었다. 그렇지만 본 연구에서 전화정평가 항목에 기록된 모든 관련 정보가 환경 영향에 고려되지 않았기 때문에 Eco-indicator 95 method를 농업생산 체계에 적용할 때 몇 가지 난제에 부닥친다. Eco-indicator 95 method에 토양 및 자원의 이용과 같은 몇 몇 중요한 환경적인 문제가 포함되지 않았으며, 이 방법의 다른 문제는 환경 평가를 위하여 현장 정밀연구가 수행되지 않았다는 것이다. 그렇지만 본 연구에서 얻어진 생태지표 지수를 이용하여 벼 재배에 따른 시비방법 간의 차이점을 나타내기에 충분하다고 여겨지며, 가장 높은 생태지표 지수를 나타낸 화학비료를 시용한 구에서 가장 큰 환경영향이 관측되었고, 이러한 차이점은 주로 화학비료 투입에 의한 토양중의 높은 인산 함량의 축적 때문인 것으로 여겨진다. 분석한 시비체재는 특별히 지구온난화 보다는 수계의 부영양화의 환경적인 문제에 기여되는 것으로 나타났으므로 질소 시용비율 및 시용기술 이외에 액비 시용에 따른 양분 용탈이 수계 환경에 명확히 영향을 미치는 것으로 나타났다. The suitability of the Life Cycle Assessment (LCA) methodology to analyze'the environmental impact of rice cultivation with different fertilizing systems is investigated. The first part of an LCA is an inventory of parameters used and emissions released due to the system under investigation. In the following step, the Life Cycle Impact Assessment, the inventory data were analyzed and aggregated in order to finally get one index representing the total environmental burden. For the Life Cycle Impact Assessment (LCIA) the Eco-indicator 95 method has been chosen because this is well documented and regularly applied impact assessment method. The resulting index is called Ec -Indicator value. The higher the Eco-indicator value the stronger is the total environmental impact of an analyzed few system. The rice field experiment conducted in middle parts of korea was chosen as an example for the life cycle impact analysis. In this experiment the treatments were consisted of none fertilizer plot (NF), standard fertilizer plot (SF) applied chemical fertilizers based on soil chemical analysis before rice transplan ing, and efflux fertilized plot (EF) applied with pig wastes fermented as the same rates of SF plot as basis on total nitrogen content. The obtained Eco-indicator values were clearly different among the treatments in the rice trial. The total Eco-Indicator values for SF and EF have been observed 58 and 38% relative to the NF, respectively. For all the treatments the environmental effects of eutrophication contributed most to the total Eco-indicator value. The results appeared that the LCA methodology is basically suitable to assess the environmental impact associated with different fertilizer applications for rice cultivation. A comparative analysis of the fertilizing system's contribution to global warming and eutrophication is possible.