SnO₂/TiO₂후막형 습도센서의 제조 및 특성

이건동,이재현,박효덕,이덕동,최흥문 경북대학교 센서기술연구소 1991 센서技術學術大會論文集 Vol.2 No.1

SnO_(2) doped with TiO_(2) and other activating agents, is used as a raw material to prepare humidity sensors. SnO_(2) is an n-type semiconductor whose resistance is described as a function of relative humidity. SnO_(2)/TiO_(2) thick film humidity sensors have been fabricated by using typical silk screen printing techniques. The humidity sensitivity of SnO_(2)/TiO_(2) thick film has been investigated. And the sensing characteristics of the fabricated SnO_(2)/TiO_(2) sensors such as resistance change and response time, has been investigated from R.H.20 % to 90 %. Experimental results show that the impedance-humidity characteristics of the humidity sensors depend on the microstructure of surface roughness and pore size distribution.

악관절 내장증환자에서 관절돌기의 후방경사에 관한 연구

이건일,유동수 大韓口腔顎顔面 放射線學會 1991 Imaging Science in Dentistry Vol.21 No.2

This study was designed to investigate the effects of the posterior slope of the articular eminence and the condylar angulation to the posterior slope of the articular eminence on internal derangement of TMJ. The materials consisted of 78 transcranial oblique lateral projections of 31 normal subjects and 47 interal derangement patients. The reults were as follows: 1. The posterior slope of the articular eminences in normal group were large than that in abnormal group, but there were not significant differences between each group about the condylar angulation to the posterior slope of the articular eminences. 2. The differences between in the right and left sides in patients who were affected unilaterally and bilaterally were larger than that in normal groups. 3. In patients affected unilaterally, there were not significant differences between affected joints and unaffected joints about the posterior slope of the articular eminence and the condylar angulation to the posterior slope of the articular eminence. 4. In abnormal group, there were significant differences between each group about condylar angulation to the post, slope of the articular emienece (ant. disk displacement without reduction>fibrous adhesion>ant. disk displacement with reduction), but not about the post, alope of the articular eminence.

Efficient Construction Process and Distribution System through Construction IT Convergence based on 4th Industrial Revolution Technology: Focused on Distribution Management of Free-form Structural External panel

Lee,Dong-Woon,Kim,Dae-Geon 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-

The distribution of construction materials and the schedule management of a project are important elements in ensuring an effective construction system and reasonable construction duration and cost. Therefore, IT convergence technology of distribution to the construction industry, a BIM module is composed as a 4D model more easily, which is considered to contribute to a reduction in construction duration, an improvement in quality and a reduction in cost through efficient management of manpower and the minimization of errors arising from the site construction by reflecting information in real time through an RFID system.

경량, 고압의 CNG 복합재료 압력용기의 설계에 관한 연구

이동건,하성규 한양대학교 공학기술연구소 1993 공학기술논문집 Vol.2 No.1

A design study of a multilayered CNG(compressed natural gas) pressure vessel subjected to high internal pressure and temperature loadings is presented Layers of the vessel are composed of aluminum liner and tar-ups of composite laminate having the lightweight, high strength and stiffness. Geometrically nonlinear finite element analysis allowing large deformations and thermal effects, is based on nonlinear shell theory and the laminate theory, is utilized for the stress analysis. Tsai-Wu failure criterion for the strength analysis is also used. The results of the stress and strength analysis are examined and discussed. Futher, design study of a multilayered pressure vessel for operating at 20MPa of internal pressure and -60℃ ∼60℃ temprature environments is presented.

깁스표본기법을 이용한 와이블분포의 위험률에 대한 베이즈추정

조건호,이우동,신양규,윤용화 慶山大學校 基礎科學硏究所 1998 基礎科學 Vol.2 No.1

와이블분포를 따르는 표본을 이용하여 위험률을 베이지안 방법을 이용하여 추정한다. 깁스표본법을 베이지안 추정에서 사후확률의 분포를 구하는 방법에 적용하여 위험률에 대한 사후분포와 주변사후분포를 추정하는 방법을 제안한다. 그리고, 9개의 가솔린 정류에서 쓴 sdufwjsekfrlrn(heat exchanger)에 대한 수명시간자료를 이용하여 제안된 방법으로 위험률에 대한 베이즈추정량을 구하고 최우추정량과 비교한다. In this paper, a Bayesian estimation of the hazard rate function of Weibull distribution is considered. Using Gibbs sampling approach, the posterior distribution of hazard and Bayes estimator of hazard are presented. Using 9 heat exchanger data, the proposed method is illustrated.

지수분포를 따르는 가속수명자료의 적률추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 적률추정량에 기초한 불편추정량(unbaised estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

지수분포를 따르는 가속수명자료의 최우추정법에 기초한 경험적 베이즈 예측분석

조건호,이우동,하일도 慶山大學校 基礎科學硏究所 1997 基礎科學 Vol.1 No.2

본 논문은 지수수명분포에서 제2종 중도절단된 가속수명자료를 이용하여 고장률의 사전분포의 평균을 알 때, 정상조건하에서 하나의 미래 관찰치의 예측문제를 사전분포의 모수에 대하여 최우추정량(Maximun Likelihood estimator)을 이용하는 경험적 베이즈 접근방법을 적용시켜 경험적 베이즈 예측분포와 예측구간에 대하여 연구하였다. In accelerated life tests(ALTs), the failure time of a test item is observed under high stress conditions, and based on these data, one intrests statistical inference on the parameters of lifetime distribution at the normal stress. Under the type-II censoring, we assume that the life distribution is exponential distribution. When the information on the prior is partially known, we device the empirical Bayesian analysis of ALTs data in order to obtain the empirical Bayesian predictive density and predictive intervals for a future observation under the normal stress level.

정신분열병 또는 정신분열형장애를 가진 입원환자에서 Risperidone과 Olanzapine의 효과의 비교 : 6주간의 개방적 전향적 연구 6 Weeks, Open-Labelled, Prospective Study

김찬우,이동건,강승훈,조지현,이수진,조동환,김정기 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.2

Objectives : Risperidone and olanzapine, which are atypical antipsychotics. are widely used in the treatment of schizophrenia as the 1st line drug, proving their effectiveness for both positive and negative symptoms. They also have many advantages even from the side effects. However, they show differences with the chemical structure and pharmacokinetics and they work differently to receptors. Researchers have studied the effect and side effect during the acute phase of schizophrenia as an open prospective study. Methods : Forty subjects with DSM-IV schizophrenia or schizoaffective patients including 1) 1st onset schizophrenia patient, 2) patient who has been treated by the prior antipsychotics and not improved or even worse to be admitted again, were assigned to receive risperidone or olanzapine for 6 weeks. Psychopathology, adverse effect. weight change, fasting serum glucose, and drug cost were compared within and across groups. Results : After 6 weeks later both treatment groups showed the significant decrease in PANSS positive, general psychopathology and total score while they did not show any significant difference between two groups. Risperidone group, however. showed the significant decrease in PANS negative score, which olanzapine group did not. In terms of adverse effect risperidone group showed more extrapyramidal symptom than olanzapine group. Body weight rised significantly after Gweeks, but no significant difference between two treatment groups. There were no significant indrease of fasting serum glucose level. Conclusions : Risperidone and olanzapine are effective drugs which can be used during the acute phase of schizophrenia. Risperidone is expected to shorten the admission day and remission of the symptom of acute phase, mile olarizapine is more advantage in a neurologic side effect than rispendone.

급성 지주막하 출혈에 동반된 관상동맥 연축에 의한 심근경색증 1예

부귀범,박근호,양종태,이동민,장성종,김건영,장경식 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.1

In many cases, acute cerebrovascular disease is accompanied by abnormal electocardiograms. Also, though rather uncommon, acute myocardial infraction is also seen. The mechanism of its occurance is uncertain but it is thought to be related to coronary artery spasms, an abnormal autonomic nervous system, and a catecholamine increase. A female patient of 34 years of age came to the hospital because of sudden headache accompanied by substernal chest pain. A subarachnoid hemorrhage due to a cerebral aneurysm rupture had occured, and there was ST segment elevation in lead II, III, and aVF of the electrocardiogram. A cardiac enzyme test, an echocardiography, and a coronary angiography were performed, and she was diagnosed to have acute myocardial infarction due to coronary artery spasm. Clipping of the aneurysm was performed. With the use of nitrate and an angiotension converting enzyme inhibitor, the condition of the patient improved.

정신분열병 및 정신분열형 장애에 대한 올란자핀의 효과와 안전성

안용민,강대엽,권준수,김창윤,김철응,반건호,신영민,이기철,이동우,이중서,조현상,채정호,김용식 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

연구목적 : 본 다기관 공동임상연구는 국내 환자를 대상으로 새로운 항정신병약물인 올라자핀의 치료 효과와 안전성을 확인하고자 시행되었다. 방 법 : 1999년 7월부터 2000년 3월까지 국내 10개 병원에 방문한 정신분열병 및 정신분열형 장애 105명을 대상으로 비대조 개방 임상연구를 시행하였다. 중등도 이상의 정신병 증상을 지니거나, 부작용으로 약물교체가 필요한 경우 또는 기분장애 증상의 치료가 필요한 환자를 대상으로 하였다. 2∼7일간의 약물 배설기간 후에 1일 10mg의 올란자핀을 투여하였고, 이후로 3∼7일 간격으로 용량을 조절하여 총 8주간 투여하였다. 치료 효과는 PANSS(Positive and Negative Syndrome Scale), BPRS(Brief Psychiatric Rating Scale), CGI(Clinical Global Impression-Severity), MADRS(Montgomery-Asberg Depression Rating Scale), HAM-A(Hamilton Rating Scale for Anxiety)로 판정하였다. 안전성 평가는 자발적인 이상반응 보고, 활력징후와 혈액 검사 및 SAS(Simpson-Angus Scale), BARS(Barnes Akathisia Rating Scale), AIMS(Abnormal Involuntary Movement Scale)척도를 이용하였다. 결 과 : 105명중에서 85.7%인 90명이 8주간의 치료를 완료하였다. 평균 최빈 용량은 일일 16.1(±4.7)mg이었고, 종료시점에서의 BPRS전체 점수가 기저 상태에 비해 40%이상 감소된 반응군은 69.5%이었다. PANSS의 양성 증후군과 일반정신병리 뿐만 아니라 음성 증후군 소척도에서도 유의한 감소를 보였으며, 이 감소들은 치료 초기부터 나타나서 8주간 지속되었다. 43.8%의 피험자가 중등도 이상의 우울증상을 같이 지니고 있었으며, 올란자핀에 의해 MADRS와 HAM-A가 유의하게 감소하였다. 치료 기간 동안에 활력징후에는 뚜렷한 변화가 없었으나 체중은 8주간 지속적으로 증가하였다. SAS와 AIMS는 감소하였으며, 정좌불능증을 제외한 나머지 추체외로 증상의 발생비율도 낮았다. 임상적인 증상이나 징후를 동반하지 않는 ALT/SGPT의 상승을 보였지만 프로락틴을 포함하는 대부분의 혈액 검사상 뚜렷한 이상 변화는 없었다. 결 론 ; 비록 본 임상연구가 비대조 개방 임상연구로서 많은 제한점을 가지고 있지만, 올란자핀이 기존 약물에 내약성을 보이거나 기분증상을 동반하는 정신병에 치료 효과가 있었다. 그리고 기존 항정신병약물 치료시에 문제가 되었던 추체외로 증상과 고프르로락틴 혈증을 포함하는 대부분의 부작용면에서 안전성을 보여 주었다. Objective : This multicenter clinical trial was carried out to investigate the efficacy and the safety of olanzpine for the treatment of Korean patients. Mothod : 105 patients with schizophrenia and schizophreniform disorder, visited at 10 mental or university hospitals, had received an open and non-comparative treatment with olanzapine for 8 weeks. Patients had psychotic or depressive symptoms with the severity above moderate degree or intolerable side effects to previous antipsychotics. After a wash-out period of 2-7 days, 10mg olanzapine was prescribed initially to all the patients, and then the dosage could be adjusted within the range of 5-20mg/day of olanzapine by 3-7 days. Results : 90(85.7%) of 105 patients completed the 8-weeks trial and the mean modal dose of olanzapine was 16.1(±4.7%)mg/day. At the end of the trial, 73 patients(69.5%) were classified as responder, which was defined as 40% or more improvement in BPRS(Brief Psychiatric Rating Scale) score comparing to baseline. There was a significant reduction in the scores of PANSS(Positive and Negative Syndrome Scale)and subscales including negative symptom scores and CGI. Also weekly analysis showed that the reductions in scores were kept on for the whole period of the trial. 43.8% of all the patients had depressive symptoms at the baseline and total scores of MADRS(Montgomery-Asberg Depression Rating Scale) and HAM-A(Hamilton Rating Scale for Anxiety) were also reduced after the trials. Vital signs revealed no clinically significant changes but continuous weight gain was observed during the treatment with olanzapine. The scores of SAS(Simpson-Angus Scale) and AIMS(Abnormal Involuntary Movement Scale) for assessing the EPS(extrapyramidal symptoms)and tardive dyskinesia respectively were significantly decreased and only a few patients reported EPS as adverse events. Although mild and clinically non-significant of ALT/SGPT was observed, most laboratory parameters including plasma prolactin level showed to significant changes during the trial. Conclusions : Although this trial had many limitations because it was a non-comparative and open study, olanzapine showed high efficacy on the positive, negative and depressive symptoms in schizophrenia and schizophreniform disorder.In addition to that, olanzapine showed a substantially favorable safety profile, such as low incidence of EPS and hyperprolactinemia.