심근경색의 위험인자로서 Thrombomodulin유전자변이의 의의

박현영,김영미,권혁문,지선하,조승연,정남식,심원흠,장양수 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.6

관절염 환자의 실태와 관련요인에 대한 분석적 연구

정승기,남철현,신두만,양숙희,김기열,이미경,문기내 대한보건협회 2002 대한보건연구 Vol.28 No.3

This study was conducted to examine the condition of patients with arthritis and its related factors. Data were collected from 100 people who suffered from arthritis in Seoul. Busan, Daegu, Daejun, Junjoo, and pohang from April 2, 2000 to July 31, 2000. The results of this study are summarized as follows : 1. 6L0% of the subjects were female. The incidence rate of arthritis was higher in the higher age group, lower educated group, and thinner group. In case of male, the incidence rate was higher in the groups of single, residents in big cities, and technicians. In case of female, it was higher in the groups of the married, residents in towns or villages, and housewives. 2. According to the parts of arthritis, knee joint covered 67.4% and backspine joint covered 9.0%. The incidence rate of arthritis was higher in the groups of forties, housewives, single, irreligious people, residents in towns and villages, primary school graduates, thin people, and walk exercisers. 3. The arthritis patients felt pain most when they stood up (31.5%). According to the time when they felt pain most, the time when they were active during daytime was 31.5% and nighttime was 29.8%. When they got up in the morning was 22.4%, while 10.9% felt pain all cay long. 4. they had arthralgia knees and cramp in crook of the knees (21.8%). Their knees ticked when they moved (21.1%). The had to rest hands on anyplace when they stood up (18.7%) and they could not completely unfold their knees. 5. The medical institutions which diagnosed them showed significant difference in the variables of sex, age, marital status, religion, place in residence, education level, economic status, obesity level, exercise, parts of arthritis, and posture of feeling pain. from above results, it can be concluded that it is necessary to develop appropriate medical treatment on the basis of the respondents' socio-democraphic characteristics, pain parts, period of having a pain, satisfaction level with treatment and its related factors. Therefore, related professionals and organizations must develop education program for prevention of arthritis in order to educate them.

환기정도에 따른 수술실용 신발 종류가 수술실 오염에 미치는 영향 : How to Choose Suitable Shoes?

남경동,정혜선,박영신,원진희,주미자,성화신,이지혜,이병희,조경숙,배재춘 한국의료QA학회 2000 한국의료질향상학회지 Vol.7 No.1

Background : Various types of protective footwear have been used to minimize bacterial contamination in operating rooms. In recent years, debate has arisen concerning the need for use of such protective footwear. This study was designed to provide useful data about choosing shoes most suitable for the surgical environment. Methods : Between November, 1999 and January, 2000, we performed this experimental study by comparing effect of three types of shoes (i.e., disposable shoescover, operating room-restricted shoes, and ordinary shoes) on bacterial contamination of operating rooms equipped with two different ventilation systems (i.e., high air-change, low air-change) respectively. Data were collected during two-hour sham operations in which subjects and their activities were strictly standardized. Bacterial flora were sampled from the study area floor and air colony-counts were measured. Results : In experiments involving high air-change ventilation system, there was a significant difference of floor contamination between three types of shoes, but no difference of air contamination. Under low air-change system, there was a significant difference of both floor and air contamination between three types of shoes. Conclusion : The results show that protective footwear would be unnecessary in the operating room with high air-change ventilation system, but it is important to choose suitable shoes carefully under low air-change system. Therefore, the use of outdoor shoes can be considered under high air-change system, but it would seem sensible to apply their first use in less bloody operations at the day surgery center or out-patient department to prevent transfer of body fluid into the outside environment.

Agrobacterium tumefaciens를 이용한 amorpha-4,11-dience 합성 유전자의 상추로의 도입

정귀미,송명종,백남인,박영두 경희대학교식량자원개발연구소 2005 硏究論文集 Vol.24 No.-

Amorpha-4,11-diene synthase(ADS) 유전자를 상추에 도입하기 위해 ADS유전자를 pILTAB357에 삽입하여 binary vector pADS를 제작하였다. 상추 형질전환은 자엽 절편체를 pADS 벡터를 운반하는 A. tumefaciens LBA4404에 접종시키고 MS배지에 200 mg·L 세파탁심과 50 mg·L 가나마이신이 첨가된 선발 재분화배지에서 선발하였다. 선발된 신초는 뿌리 유기 배지에서 뿌리를 유기한 후 뿌리가 발생한 신초는 토양으로 이식하여 재배하였다. 형질전환상추에 T-DNA가 전이되었는지를 확인하기 위해 genomic DNA를 이용하여 PCR과 Southern 혼성화 분석을 실시하였다. PCR 분석 결과 9개의 재분화 개체로부터 기대했던 1.6 kb의 산물을 확인할 수 있었으며 Southern 혼성화 분석 역시 각 재분화 개체에 ADS 유전자가 1개 내지 3개의 copy수로 전이된 것을 확인할 수 있었다. 형질전환 상추내의 artemisinin 함량을 GC와 GC/MS 방법으로 분석하였다. Artemisinin 표준물은 retention time이 10분 7초로 나타났으며 이 peak가 artemisinin인지 확인하기 위하여 GC/MS를 측정한 결과 m/z 282가 정확하게 나타나 artemisinin으로 확인되었다. 한편 형질전환 상추와 일반 대조구 상추의 시료도 GC chromatogram에서 artemisinin의 retention time인 10분 7초 부근에서 여러 peak이 겹쳐서 나타났으나 각 peak에 대하여 GC/MS를 측정한 결과 m/z 282을 나타내는 peak는 관측되지 않아 형질전환 상추와 일반 상추에는 artemisinin이 함유되어 있지 않은 것으로 확인되었다. To introduce amorpha-4,11-diene synthase (ADS) gene into lettuce plant, binary vector pADS was constructed by the insertion of an ADS gene to pILTAB357. Cotyledon explants were infected by A. tumefaciens LBA4404 carrying pADS vector to transform lettuce plant with ADS gene. Transformed shoots were selected on selective regeneration medium containing MS salts, 200 mg·L cefotaxim, and 50 mg·L kanamycin. The selected shoots were transferred to rooting medium, and regenerated shoots were transplanted to pots after roots appeared. PCR and Southern hybridization analysis of genomic DNA were performed to confirm expected T-DNA fragments in the transgenic lettuce plants. PCR analysis revealed the presence of the expected 1.6 kb product from the nine regenerants. Southern hybridization analysis also showed that ADS gene was transferred into transgenic lettuce plants with 1~3 copies. Artemisinin in lettuce was identified by GC and GC/MS analysis. Standard artemisinin was found at 10 min 7 sec in the retention time by GC analysis and confirmed m/z 282 by GC/MS. There were several peaks at retention time of both non-transformed and transformed lettuce plants. However, GC/MS analysis showed that peak with m/z 282 was not found in transgenic lettuce plants.

정신장애인에 대한 일반인의 스티그마와 정신장애인이 지각하는 스티그마의 비교 연구

서미경,김정남 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : The purpose of this study is to compare public stigma against mental patients and mental patients' perceived stigma. Methods : 549 members of general populations participated in the survey which included questions regarding prejudice and discrimination against mental mental patients, while 377 mental patients participated in the survey which included questions regarding perceived prejudice, experienced discrimination and a coping orientation to social stigma. Results : The mental patients perceived prejudice more compared to public prejudice toward the mental patients. And they experienced discrimination less compared to public's practice of discrimination against mental patients. Also mental patients used passive-avoidance coping orientation against social stigma. Conclusion : This study concluded that consumer empowerment program for mental patients is just important as anti-stigma campaign.

일부지역 대학생의 삶의 질에 영향을 미치는 제 요인

류미경,박경민,김정남 대한보건협회 1999 대한보건연구 Vol.25 No.1

본 연구는 일개 대학생을 대상으로 학교 환경 만족도, 학교내·외 안전에 대한 인식도, 학생활동참여도, 스트레스 관리, 건전한 건강실천행위 등 대학생의 삶의 질에 영향을 끼치는 환경요인과 건강관련 요인을 분석하여 대학생의 건강지향적 삶을 향상시키기 위한 프로그램 개발시 기초자료를 제시하고자 한다. 대구시에 소재하는 K대학교의 대학생 중입학 후 한학기 이상 학교생활을 경험한 대학생 500명을 대상으로 1998년 10윌 26일부터 11월 7일까지 2주동안 설문지를 배부하여 자료수집을 하였다. 연구도구로 조사대상 대학의 학교내 환경만족도 15문항(강의실만족도 6문항, 도서실 만족도 6문항, 교내 환경만족도3문항), 교·내외 안전에 대한 인식도 2문항, 교내 및 학교 주변 사고에 대한 직접경험 및 간접경험 4문항(도난사고, 폭력사고, 성폭력사고, 교통사고), 학생활동 참여도 3문항(동아리 활동, 총학생회 활동, 학생회 활동)을 조사하였으며 건강 실천 행위는 Breslow index를 이용하였다. 스트레스 관리는 Walker 등이(1987)이 개발한 건강증진생활양식(Health Promoting LifeStyle Profile)을 서(1995)가 수정보완한 것으로 대학생에게 적합한 스트레스 관리의 7문항을 신정하여 이용했으며, 삶의 질은 노(1988)가 개발한 도구를 이용하여, 서술통계방법, Pearson's correlation coefficient, stepwise multiple regression으로 분석한 결과 다음과 같은 결론을 얻었다. 학교환경에 대한 만족도는 평균점 2.72(SD=.54)로 낮은 수준이었다. 하위영역별 평균점은 강의실 만족도 2.36(SD=.55), 도서실 만족도 2.84(SD=.67), 교내 환경 만족도 2.96(SD=.54)이었다. 교내·외 안전에 대한 인식도는 교내안전인식도가 2.60으로 학교주변안전인식도 2.23보다 높게 나타났다. 교내 혹은 학교 주변에서 사고를 경험한 비율은 도난사고의 경험율이 가장 높게 나왔으며, 폭력사고와 성폭력사고도 자신이 경험한 경우보다 타인의 경험을 들었다는 경우가 비율이 높게 나왔다. 건강 실천 행위는 Breslow Index가 0∼3점인 군이 54.3%이며 4∼5인 군이 42.7%이며 6∼7인 군이 3.0%를 차지하여 97.0%가 나쁜 건강행위를 하는 것으로 나타났다. 스트레스 관리의 항목에서 전체적인 스트레스 관리의 평균점은 2.27이며, 하위영역으로 스트레스원이 무엇인가를 아는가는 평균점이 2.92이며, 스트레스를 해소하기 위해 특별한 방법(예: 이완요법)을 이용하는가는 평균점이 1.64로 가장 낮았다. 이는 자신들의 스트레스원에 대해 인지는 하고 있으나 올바른 스트레스 관리를 못하고 있음을 알 수 있다. 대학생의 영역별 삶의 질은 가족관계가 평균점3.49로 가장 높았으며 이웃관계, 자아존중감, 정서상태, 신체상태와 기능, 경제생활 순으로 나타났다. 삶의 질에 영향을 주는 요인을 단계적 중다회귀분석으로 분석한 결과, 스트레스 관리, 성별, 학교내 환경만족도, 보건학 수강유무, 건강실천행위가 삶의 질을 21.0% 설명하였다. 이상의 연구 결과를 기반으로 다음과 같은 제언을 한다. 1. 대학생의 특성, 환경, 복지에 적합한 구조화된 삶의 질 측정도구의 개발이 필요하다. 2. 대학생 올바른 건강실천행위와 스트레스 관리를 위해서 교내 보건교과목의 수강기회를 늘리고 건강증진프로그램과 스트레스 관리 프로그램의 도입과 강화가 필요하다. The purpose of this study, using a college student as the subject of study, are to analyse the satisfaction with the school circumstances, recognition about the security in the school and outside the campus, participation in school activites, managing the stress and practicing the sound health behavior, and to provide a basic material for programs which improve the health life quality of students. A Questionair test was done to K University students who have attended the school at leas! for a semester over two weeks (1998. 10.26-11.7). The Questionair includes 15 questions on the satisfaction with school surroundings (6 on classroom, 6 on library and 3 on circumstances in the school), 2 questions on the recognition about security on the campus and outside the school, 4 questions on direct and indirect experiences (thief, violences, sexual violence, traffic accident), 3 questions on participating in student activities(club activities, student's association). Breslow Index was used to check health practicing behavior. For the management of stress, out of Health Promoting Life style Profile, originally developed by Walk et al, and modified by Seo(1995), 7 items appropriate for student were chosen and Quality of life Scale developed by Noe(1988) was used to check Quality of life of college student. Next step, I used them to get Descriptive statistics, Pearson's correlation coefficient, stepwise multiple regression. The results are as follows: The satisfaction with school circumstances is low, whose average is 2.72 (SD=.54), And the satisfaction average on classroom is 2.36(SD=.55), on library is 2.84 (SD=.67), on circumstance in the school is 2.96 (SD=.54), The recognition about security on the campus is 2.60, higher than 2.23 outside the school. Theft experience is the highest. In the case of violence and sexual violence, indirect experience rate is higher than the direct one. For health practice behavior, Breslow index 0-3 group accounts for 54.3%, 4-5 group 42.7%, and 6-7 group 3.0%, which means 97.0% practices unhealthy behavior. For the management of stress, total stress managing average is 2.27; average on knowing the origin of stress is 2.92, and average on using the way of solving stress is the lowest 1.64. It can be inferred that they recognize the origin of stress but don't know how to deal with it. For the Quality of Life, the average on family relationship is the highest 3.49 and neighborhood relationship, self esteem, emotional conditions, physical conditions and function and economy life in order. When analysing the factors affecting life quality through 'stepwise multiple regression' method, stress management, sex, satisfaction with the circumstances in the school, taking health class or not, and practicing health behavior account for 21.0%. Accordingly, 1. Developing the organized tool to measure quality of life is needed, taking the characteristics of student, circumstances and welfare into consideration. 2. To establish the sound health practice behavior, there is urgent in need that the opportunity taking health subject should be increased, and health program and stress management program should be introduced and reinforced.

서울 지역 대학생의 식습관 및 식생활태도에 관한 조사

최순남,정남용,윤미은 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.1

This study was to investigate the food habits and the dietary behaviors of university students. Questionnaires were completed by 492 students in five different departments. The data were analyzed by SAS program. The results are summarized as follows: Fifty(10.2%) of respondents were vegetarians, 81(16.4%) were heavy meat eaters and all the others were light meat eaters. All students had their biggest meal at supper. Three hundred and ninety-three(79,9%) of the respondents usually had rice for breakfast. Three hundred -sixteen(64.2%} ate 3 meals a day, 155(31.5%) ate 2 meals and all the others ate 1 meal or more than 3 meals. The length of mealtime was 30 minutes in 268(54.5%), 10 minutes in 209(42.5%) and more than 1 hour in all the others. Respondents considered taste the most important meal factor with nutrition, hygiene, and amount ranked accordingly. A majority(63.0%) of respondents ate occasionally ate between meals, while 28.1% snacked frequently, and 8.9% ate no snacks. Although nutrition dept. students had studied nutrition subject, some results of nutrition dept. students were desirable and others were undesirable in dietary behaviors. Therefore they should have a nutritional education program to improve their food habits and the dietary behaviors for students' health. And nutritional education program should be organized practically and systematically.

服飾변천 과정에서 Sleeve Design의 特徵(Ⅲ) : 16세기를 中心으로 Sixteenth Century

姜京子,鄭雲子,鄭福南,秋美先 慶尙大學校 1985 論文集 Vol.24 No.1

The sleeve design of costume had an impact on the general pattern of costume in 16th century. In this paper the characteristics of the change sleeve design and the method of construction were studied according to the criteria suggested by Cunnington. The results of the study can be summerized 35 follows. The costume in 16th century was not quite different from those in the past centuries, but the costume tended to have more varied detail and trimming and they were based on the graceful silhouette. In 16th century, there were no uniformity and regularity of sleeve design. But it was general trend that sleeve was expanded by using pad and slash of· it had very tight sleeve in the early part of 16th century. The tight sleeve of women's costume in Germany was tailored in two part, and it suggested the improved technic of cutting. On the other hand, the sleeve of women's costume in France and England had the artificially distorted from that had expanded form in the lower part. In the middle part of 16th century, the form of sleeve became very complicated and it was inconvenient for the wearer to put it on. Therefore, in France, the sleeve was made independently. When one put it on, a string was used to connect it to costume and to decorate with E´aqaulette. The upper part and wrist part of elbow sleeve of Over-coat in Italy were very tight, and the middle part of it was loose. The typical pattern of women's costume that had expanded sleeve in lower part was in fashion. This form disappeared in 13th century and appeared again in 14th and 15th centuries. In the part of 16th century, the sleeve design manifested the aesthetic sense of that period, Many kinds of sleeves Including the tight one, baggy one, wide one and the hanging one were used. The most characteristic sleeve of this period was the expanded leg of mutton sleeve and it was in fashion for men and women in upper classes of France and England. In short, all kinds of sleeve suggested by Cunnington appeared in this period. They include both the natural and artificial forms. As the sleeve design had varied form and the expression in detail was stressed. These style helped to harmonize the sleeve with the design for body,and they contributed to increase the splendor of costume in 16th century.

지역학으로서의 독일학 육성을 위한 정보자료의 디지털화와 활용방안에 관한 연구

최병진,정동규,천미애,남유선 한국독어독문학회 2003 獨逸文學 Vol.88 No.-

In dieser Arbeit wurde vor allem versucht, den Blick auf zwei Punkte zu richten: Erstens sollte das Forschungsvorhaben, das im Rahmen eines zweija¨hrigen Projekts unter finanzieller Unterstu¨tzung des Koreanischen Research Foundation (KRF) durchgefu¨hrt wurde, in grobem Abriss vorgestellt werden. Zweitens werden die Probleme skizziert, die wa¨hrend der Durchfu¨hrung des Projekts auftauchten, und aus denen sich schließlich unmittelbar einige Verbesserungs- vorschla¨ge ergeben. Das Projekt hatte die Aufgabe, ein auf digitalisierten Daten basierendes Informationssystem u¨ber Deutschland zu erstellen. Das System der Wissenschaftsinformationen, das in der vorliegenden Arbeit vorgestellt wurde, wird beispielsweise aufgrund seiner umfangreichen Informationsdaten dem Fach Germanistik zur weiteren und vertiefenden deutschlandeskundlichen Forschung von großem Nutzen sein. Daru¨ber hinaus aber kommt es auch den Lehrenden zugute, da ihnen dann ein vielseitiges und reichhaltiges Lehrveranstaltungsmaterial als Veranstaltungsthemen zur Verfu¨gung steht. Um ein solches Wissenschaftssystem der Deutschlandforschung zu erstellen und weiter zu entwickeln, wird jedoch nicht nur vie1 Zeit, sondern eine sta¨ndige Aktualisierung der Datenbank no¨tig werden. Um diese Aufgaben zu bewa¨ltigen, sollten mo¨glichst viele Germanisten fu¨r das Projekt zur Verfu¨gung stehen. Zurzeit findet das Internet im privaten und o¨ffentlichen Bereich breite Anwendung wie noch nie zu vor, und diese Tendenz wird sich noch versta¨rken. Forscher suchen und sammeln Informationen anhand des Internets. So nimmt es im Forschungsleben als Forschungswerkzeug einen wichtigen Platz ein. In Zukunft wird sich der Service im Bereich des Netzwerks weiter entwickeln/verbessern. Dies bedeutet fu¨r die Forscher eine Chance im Hinblick auf die Zukunft der Forschung, wenn sie gemeinsam ein wissenschaftliches Kooperationssystem entwickeln, um Wissen unter einander auszutauschen.

유아의 사회적 역할놀이에 대한 교사들의 인식

박찬옥,정남미 中央大學校 韓國敎育問題硏究所 1996 韓國敎育問題硏究所論文集 Vol.- No.11

The purposes of this study were to examine the patterns of teacher intervention in children's sociodromatic play at kindergarten, to investigate the perception of teachers concerning sociodramatic play, and to grope the effective strategies of teacher intervention. The results of this study were as follows ; 1. Most of kindergarten had settings and objects for sociodramatic play. However, they were limited to play house and household appliance. 2. Most of Kindergarten teachers recognized that sociodramatic play had influence on social, emotional, language development for children, and most of them involved in sociodramatic play for supporting and activating. 3. But most of them didn't make lists of props (equipments) and plans for sociodramatic play. 4. In general, they eveluated children's sociodramatic play. 5. The pre-service and in-service teacher traing for the effective intervention methods of sociodramatic play didn't well excute. 6. The effective intervention strategies contains changing the play themes, sharing the background informations for them, providing sufficient time, space, props, and teachers' prompting by the steps of planing, developing, and evaluating about the play activity.