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      • 염모제 도포방법에 따른 인체 적혈구의 산화스트레스 비교

        김영철,심미자,권정숙 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.2

        To ascertain the effects of hair dyeing application on oxidative stress in human, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp(conventional dyeing) and a hair dyeing with 3 to 4mm away from the scalp(alternative dyeing) were applied to each 15 young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours after the hair dyeing, and antioxidant enzyme activities and antioxidant contents were measured in red blood cells. After increased, malondialdehyde(MDA) contents for conventional dyeing group was shown to a tendence for more increased than alternative dyeing group. After dyeing, reduced glutathione(GSH) contents for conventional dyeing group was shown to a tendence of more decreased than alternative dyeing group. After dyeing, superoxide dismutase(SOD) and catalase(CAT) activities were significantly decreased in conventional dyeing group(p<0.01), however, SOD and CAT activities were not significantly decreased in alternative dyeing group. After dyeing, there was no significant decrease in glutathione peroxidase(GPX) activity both for conventional dyeing group and alternative dyeing group. Therefore, after dyeing, the degree of oxidative stress in red blood cells for alternative dyeing group was appeared to be lower than conventional dyeing group.

      • EPRCA 스위치의 성능 개선 연구

        김종근,천성권,강병욱 嶺南大學校 工業技術硏究所 1998 工業技術硏究所論文集 Vol.26 No.1

        Latest, requirements of service of high speed traffics have increased, because these traffics are difficult to predict owing to its bursty occurrence. ATM(Asynchronous Transfer Mode) serves ABR(Available Bit Rate) service for these traffics. When concentrated high speed traffics are arrived, cell loss and cell transfer delay are occurred because statistical multiplexing of ATM raise states of congestion on network. To minimize these influence of congestion, reactive control scheme which takes advantage of feedback information should be used, in this case using preventive control scheme is insufficient. In this paper, we applied variable threshold to determine the congestion in switch node, controled transmission rate dynamically. We simulated our model and analyzed to compare our schemes to the previous ones. The results show that the average transmission rate increased up respectively. The ramp-up time that is the amount of time from the idle state to the balance state is shorter, the maximum number of cells which is much related to cell loss is less, and the control cycle of transmission rate is shorter compared to the previous methods.

      • KCI등재
      • 염모제 사용에 의한 인체림프구의 DNA 손상 변화

        김영철,심미자,권정숙 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.1

        To ascertain the effects of hair dyeing application on the DNA damage in human lymphocytes, a mixture of permanent black colored hair dye with the same amount of oxidant containing 6% hydrogen peroxide was used. A hair dyeing with contacting the scalp(conventional dyeing) and a hair dyeing with 3 to 4mm away from the scalp(alternative dyeing) were applied to each 15 young healthy women. Blood was taken from the brachial vein at two sampling times, just before and 6 hours after the hair dyeing, and tail extent moment(TEM) and tail length(TL) were measured by using a comet assay. After dyeing, TL was significantly increased in both conventional dyeing group and alternative dyeing group compared with before dyeing as an average of 47% and 28%, respectively, and TL for conventional dyeing group was higher than alternative dyeing group as an average of 1.2 fold. After dyeing, TEM was significantly increased in both conventional dyeing group and alternative dyeing group compared with before dyeing as an average of 192% and 76% respectively, and TEM for conventional dyeing group was significantly higher than alternative dyeing group as an average of 1.7 fold. Therefore, alternative dyeing application was induced to lower lymphocyte DNA damage than conventional dyeing application, and TEM was appeared to be a more sensitive tool for the measurement of lymphocyte DNA damage than TL in this study.

      • X선 촬영인자의 변화에 따른 영상의 주관적인 화질 평가

        권덕문,박명환,김성환,박종삼,이준일,남효덕 대구보건대학 2001 대구보건대학 論文集 Vol.21 No.-

        In this study, visual recognition of X-ray images were estimated using hawlet charts. The resolution has achieved excellent result when densities of film were 1.0~1.5. The more thickness of object was increase, the more the resolution was decrease, because scattered X-ray were increased. The more distance of object to film was increase, the more the resolution was decrease, because groedel effect. The more focal spot size was increase, the more resolution was decrease, because unsharpness was increase. The more field size was increase and grid ratio was decrease, the more resolution was decrease, because scattered X-ray were increase. As a result, we could to improve image quality by determination of resolution according to Radiography parameters. And, we proved that hawlet charts were useful for estimate of image quality and set up x-ray radiography.

      • KCI등재

        전위된 상악 견치 및 하악 측절치의 치험례

        권해숙,현홍근,김영재,김정욱,장기택,김종철,한세현,이상훈 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.4

        Tooth transposition is an anomaly of eruption characterized by the interchanged positions of two adjacent teeth, which is divided into complete and incomplete transposition. There are three common approaches for treating transposition: aligning the involved teeth in their transposed positions, moving them to their correct anatomic position in the arch and extracting one of the transposed teeth. Considerations in treatment plans are esthetic, function, risk of jeopardizing the roots and damaging the supporting structures, position of the root apex, developmental stages of teeth and expected compliance. The presented case reports described one maxillary canine-the first premolar transposition and two mandibular lateral incisor-canine transpositions. The former transposed teeth were arranged in their transposed position, and the latter transposed teeth were rearranged into their normal position. 치아전위란 인접한 두 치아의 위치가 서로 바뀐 치아 위치 이상을 말하며, 치관과 치근의 위치에 따라 완전전위와 불완전전위로 나눌 수 있다. 하악보다는 상악에 편측성으로 호발하며, 특히 상악 견치에서 자주 발생한다. 전위는 발견 시기와 전위된 양상에 따라 치료방법이 달라질 수 있다. 본 증례는 상악 견치와 제1소구치 간의 전위가 일어난 10세 7개월의 환아와 하악 측절치와 견치 간의 전위가 일어난 8세 11개월 환아와 8세 9개월 환아의 교정치료에 대한 것으로 양호한 치료 결과를 얻었고, 증례 별로 치료방법의 차이점에 관한 고찰을 하였기에 이를 보고하는 바이다.

      • KCI등재

        유치 수복물에 따른 주변 법랑질의 탈회 저항성 : QLF를 이용한 연구

        권해숙,현홍근,김영재,김정욱,장기택,김종철,한세현,이상훈 大韓小兒齒科學會 2010 大韓小兒齒科學會誌 Vol.37 No.1

        본 연구에서는 유치 수복물의 불소 방출 여부에 따른 주변 법랑질의 탈회 저항성과 재광화 효과를 살펴보고자 하였다. 건전 유전치 48개를 16개씩 임의로 세 군으로 나누어, FiltekTM Z250(1군), F2000(2군), KetacTM N100(3군)을 사용하여 제조사의 지시에 따라 충전하였다. 3일 동안 인공 우식 병소를 유발한 후, 14일 동안 인공 타액에 담가 재광화를 유발하였다. Quantitative light-induced fluorescence(QLF)를 이용하여 실험 단계와 시간에 따른 무기질 소실량(ΔQ)의 변화를 관찰한 결과는 다음과 같다. 1. 탈회가 일어난 인공 우식 병소의 ΔQ 값은 3군, 2군, 1군 순으로 작게 나타났고, 이 중 3군은 1군에 비해 유의한 탈회 저항성을 보였다. 2. 1군, 2군, 3군 모두 재광화 1일 후부터 초기 인공 우식 병소의 ΔQ 값과 비교 시 유의한 차를 보였으며, 관찰 기간 동안 지속적인 증가 양상을 나타내었다. 3. 재광화 속도를 의미하는 Δ(ΔQ)/일 값은 각 군에서 처음 1일 동안 유의성 있게 크게 나타났으며, 그 이후 급속히 감소하였다. 4. 수복 재료에 따른 재광화 정도는 각 군 간에 유의한 차이가 없었다. The objective of this in vitro study was to detect and monitor demineralization and remineralization of primary teeth according to restorative materials using quantitative light-induced fluorescence (QLF). A single bur hole was drilled on the each sound forty eight primary anterior teeth, and the specimens were divided into three groups. The cavity was restored with FiltekTM Z250(Group 1), F2000(Group 2), KetacTM N100(Group 3) following the manufacturer's instructions. The teeth were subjected to the demineralizing buffer for 3 days, and then subjected to a remineralizing buffer for 14 days. The change of mineral loss(ΔQ) according to the stages was evaluated by QLF and the following results were obtained: 1. When demineralization was done, ΔQ was increased as follows. : Group 1 (-110.79 ± 27.77) < Group 2 (-104.84 ± 28.95) < Group 3 (-90.16 ± 21.87) : Resistance to demineralization was statistically significant in Group 3. 2. There was a statistically significant increase in ΔQ of all groups since 1st day of remineralization 3. The rate of remineralization, Δ(ΔQ)/day, showed significant high value in each group on the 1st day then decreased rapidly. 4. There was no statistically significant difference in the degree of remineralization among restorative materials.

      • 정상인과 뇌졸중환자에서 운동유발전위의 평가

        김동현,박종현,권오상,김두응 중앙대학교 의과대학 의과학연구소 1997 中央醫大誌 Vol.22 No.2

        Since the development of magnetic stimulation as a way of assessing the function of central motor pathways, various neurologic diseases have been investigated by motor evoked potentials(MEP). This study was carried out to evaluate the usefulness of clinical application of MEP to the stroke patients. MEP were elicited with transcranial cortical stimulation using a magnetic coil in 21 healthy subjects and 18 stroke patients. Average of age was 37.5±18.0 and 63.7±7.7 years in normal and patient groups respectively. All stroke patients had a mild to severe clinical unilateral motor weakness, and also were proven to have unilateral infarction or hemorrhage at various regions of brain radiologically. During MEP studies, neither significant side effects nor pin were encountered. MEP latency of abductor pollicis brevis(APB) and extensor digitorum brevis(EDB) in controls measured 22.4±2.0 msec and 41.8±2.9 msec respectively. Normal central motor conduction time(CMCT) was 9.7±1.6 msec and 19.3±2.3 msec respectively. The amplitudes of MEP were not reliable due to great variability. Abnormal responses were noted in 5 patients on the APB and in 12 patients on the EDB motor evoked potentieal studies. Mean latency and CMCT were significantly prolonged in involved sites of the other 16 patients, comparing with control data. Prolonged latency and CMCT, increased inter-side difference of CMCT. Any potential was not a useful indicator in determining abnormality of MEP study. More paralyzed patients were apt to show abnormal responses in MEP studies. There were also more abnormal results during acute stage compared with chronic stage More abnormal results were observed in the patients with cerebral cortex or corona radiata involvements. It is suggested that MEP study is a useful and sensitive method in the evaluation of stroke patients and be a effective method for further understanding of central motor system.

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