Clear cell sarcoma of the kidney : Immunohistochemical study and flow cytometric DNA analysis of 7 cases

Choi, Yoon-Jung,Jung, Woo-Hee,Jung, Soon-Hee,Park, Chanil Yonsei University, College of Medicine 1994 Yonsei medical journal Vol.35 No.3

급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

초보선수 경기력 향상을 위한 심리적 준비의 응용 스포츠 심리학에 관한 고찰

최윤택,정대철 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The purpose of this paper is to help coaches and instructors to improve their beginning players' athletic abilities and skills by applying mental preparation method of the sports psychology. The applied sports psychology utilizes psychological knowledge to develop, implement, and satisfy the persons concerned to the sports. The applied sports psychology includes effective improvement of sports skills, motivation to practise and endure hard drills, dealing smoothly with private matters, efforts to become a better coach, and sports psyching. The sports psyching has a variety of strategies: centering to minimize problem thought that can distract players' attention right before the game and the self-statement coping-skills, centering to decrease excessive excitement or anxiety and the self-statement coping-skills plus gradual relaxation, centering to minimize partner's psyching-out and self-statement coping-skills, recalling the best performance' to escape from the slump, setting an actual short-term goal to minimize failure or disappointment, and the coach's using check-list that helps to detect their players' sports psyching skills used. The sports psyching is a mental technology to be mastered by each individuals hard training, The beginning players can access their maximum potential through the technology acquired by sports psyching practice.

항암제(Adriamycin, Cyclophosphamide, 5-Fluorouracil)로 유발된 흰쥐의 간독성에 대한 Squalene의 효과

최영복,김종세,윤중식 조선대학교 기초과학연구소 1998 自然科學硏究 Vol.21 No.1

The objective of the present study was to investigate the cytotoxicity of Adriamycin〔ADM〕. Cyclophosphamide〔CP〕, 5-Fluorouracil〔5-FU〕 in mouse liver cells (group A, B, c), and the protective effect of squalene to the hepatocytes to which ADM, CP, and 5-Fu-induced cytotoxicity(group A-1, B-1, C-1) was examined by transmission electron microscope. In the group A, The cisternae of rough endolplasmic reticulum(RER) and smooth endoplasmic reticulum(SER) are dilated/disoriented at 24 hours and 48 hours. The inner and outer membrane of mitochondria are detached or destructed, and attached ribosomes of RER are diminished in number. The cisternae of the SER are dilated, and the cristae of mitochondria are disrupted at 72 hours and 96 hours. In the group A-1, the cisternae of the RER and the SER are dilated at 24 hours. The cisternae of the SER are dilated at 48 hours. The cell organelles of hepatocytes are recovered from cytotoxicity at 72 hours. At 96 hours, hepatocytes were simillar to those of normal hepatocytes. In the group B, the cisternae of RER were partially destructed and attached ribosomes were remarkable decreased at 24 hours. A number of the mitochondria were dilated and increased in number, the filamentous materials also detected at 72 hours. In the group B-1, the difference between the normal and the treated groups were not detected at 24 hours, but the few mitochondria were expanded at the 72 hours. In the group C, the nucleus was destroyed at 24 hours and 48 hours group, however, somewhat repaired at 72 hours group. The dilated inner cavity and the irregular lamellae of the RER were observed continually until 72 hours group. The inner cavity of the SER were dilated in all groups. However, the destroyed and the normal membrane were observed simultaneously at 72 hours group. The inner membrane of the mitochondria were almost repaired at 96 hours group. In the group C-1, the nucleus was a little finfluenced by the toxicity of 5-Fu at 24 hours and 48 hours, RER were observed to keep the typical lamella structure of cisternae from 24 to 72 hours group, but inner cavity kept on dilating. In SER, inner cavity were also observed to flatten from 24 to 72 hours group. Mitochondria were always shown normal. All cell organelles were similar to those of normal at 96 hours. Accordingly, it can be said that the treatment of SQ prevents the cytotoxicity of ADM, CP, 5-FU on cell organelles of liver cell and that is concerned with the formation of membrane system of cell organelles.

일부 지하철 근로자와 소방공무원의 직무 스트레스 요인 비교

윤석환,최숙정,신동훈,정인성,하정숙 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.3

색시톡신에 의한 마비독성 패류 중독 2예

최상천,박종석,정윤석 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Paralytic shellfish poisoning results from consumption of mollusks that have fed on dinoflagellates capable of producing neurotoxins such as saxitoxin. The saxitoxin is concentrated in the shellfish and acts by decreasing sodium-channel permeability, thereby blocking neuronal transmission in skeletal muscles. Symptoms including paresthesia, perioral numbness, perioral tingling, nausea, vomiting, extremity numbness, extremity tingling, dizziness, ataxia, dysphagia, and weakness have been reported. In serious cases, respiratory hold may occur up to 6∼24 hours after ingestion. Generally, the treatment for paralytic shellfish poisoning is supportive care, but mechanical ventilation is needed in serious cases acompanied by respiratory hold. We experienced two cases of paralytic shellfish poisoning. Respiratory hold was presented in one case and only mild paresthesia in the other case. After supportive management, including mechanical ventilation in former case, both patients were discharged without sequalae.

SJO¨GREN'S SYNDROME 환자에게 즉시 임프란트 술식을 행한 치험례

최정환,손동석,이지연,이윤서,안선희,이재목 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.5

The old edentulous patients experience xerostomia commonly. They have considerable difficulty in wearing tissue-supported prosthesis and high risk rate of caries. One of them is Sj□gren's syndrome patient. Sj□gren's syndrome is a chronic inflammatory autoimmune disorder that results in a lymphocyte-mediated destruction of exocrine glands. We planned to place implants immediately after extraction in this case of autoimmune disease. The advantages of immediate implant placement include considerable decrease in time from tooth extraction to placement of the final prosthesis, fewer surgical procedures, and better acceptance of the overall treatment plan. We present a case of Sj□gren's syndrome patient treated with immediate implant placement & immediate loading in anterior region and immediate implant placement in posterior region.

원룸형 다가구주택의 봄철 실내온열환경 평가

최윤정 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.5 No.-

The Purpose of this study is to evaluate indoor thermal environment of one-room type multi-family housing during springtime in order to propose design factors improving indoor environment. Physical thermal elements(indoor temperature, relative humidity, and globe temperature) in 4 subject houses selected considering of architectural factors were measured in May, 1999. Questionnaire survey for investigating thermal responses of 25 residents was carried out. The findings are as follows. 1) Indoor temperature and globe temperature are distributed 23.5~28.5℃, 23.5~28.5℃ for southern directions and 24.0~24.5℃, 24.0~24.5℃ for northern directions in a sunny day. Indoor temperature and globe temperature are distributed 22.5~25.0, 22.5~24.5℃ for southern directions and 23.0~27.5, 22.5~27.0℃ for northern directions in a cloudy day. Relative humidity are distributed 38.0~54.0%. 2) As thermal responses, 'neutral' on thermal sensation and 'slightly dry' or 'neutral' on humidity sensation show highest percentage. 3) Therefore, indoor thermal environment of one-room type multi-family housing during springtime is evaluated on the whole comfort condition. But southern direction house at midday is in somewhat hot and dry condition, and northern direction house is in somewhat cool condition all day.

자궁적출술 후 통증에 Gabapentin 의 진통효과

최종호,김창성,김은성,유건희,이윤기,문동언,윤건중 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.6

대학주변 원룸형 다가구주택에 있어서 거주자 평가에 의한 소음실태분석

최윤정 대한가정학회 2003 Human Ecology Research(HER) Vol.41 No.10

The purpose of this study is to make clear the present condition and the reason of noise in one-room type multi-family housing around the campus by residents' subjective responses. The respondents are 104 residents living in one-room type multi-family housing around the campus The results are as follows. 1) The residents show relatively non-positive responses at evening and night on the present condition of noise in outdoor and indoor of building or indoor of house unit. 2) The types of outdoor noise of building are checked frequently are 'talking loudness' and 'traffic noise'. 'Walking and talking sounds in stairs and corridors' among the types of indoor noise of building shows highest percentage. They answer 'living equipment noise' and 'water hammer' as major types of indoor noise of house unit.