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Detecting small lung tumors in mouse models by refractive-index microradiology
Chien, Chia-Chi,Zhang, Guilin,Hwu, Y.,Liu, Ping,Yue, Weisheng,Sun, Jianqi,Li, Yan,Xue, Hongjie,Xu, Lisa X.,Wang, Chang Hai,Chen, Nanyow,Lu, Chien Hung,Lee, Ting-Kuo,Yang, Yuh-Cheng,Lu, Yen-Ta,Ching, Y Springer-Verlag 2011 ANALYTICAL AND BIOANALYTICAL CHEMISTRY Vol.401 No.3
Lu, Hui-Chuan,Liu, Kai-Ling,Yeh, Chien-Ting,Chen, Ya-Jie Institute for Corpus Research 2022 Asia pacific journal of corpus research Vol.3 No.1
This study aims to apply corpus-based approach to analyze The Yellow Wall-Paper and Herland written by Charlotte Perkins Gilman, a women's rights activist in the late nineteenth-century America. Although both works have attracted feminists' attention to the woman question that concerned Gilman, discussion on her language features and their relation to the literary themes of these two works is still in need. In this corpus-based analysis, we argue that the main themes of different literary works can be revealed through linguistic patterns identified by number and gender features of nouns and pronouns in the contrast of two works and a balanced corpus. The linguistic features (number and gender) have been related with two themes, the 'group and individual' and the 'feminine and masculine', and are further interpreted in terms of mothering and feminine consciousness. By adopting linguistic approach, our study provides quantitative and qualitative evidence to verify the established themes and arguments of these literary texts.
Chen, Wen-Kwei,Liu, Ingrid Y,Chang, Ya-Ting,Chen, Yong-Cyuan,Chen, Chih-Cheng,Yen, Chen-Tung,Shin, Hee-Sup,Chen, Chien-Chang The Society 2010 The Journal of neuroscience Vol.30 No.31
<P>Treatments for chronic musculoskeletal pain, such as lower back pain, fibromyalgia, and myofascial pain syndrome, remain inadequate because of our poor understanding of the mechanisms that underlie these conditions. Although T-type Ca(2+) channels (T-channels) have been implicated in peripheral and central pain sensory pathways, their role in chronic musculoskeletal pain is still unclear. Here, we show that acid-induced chronic mechanical hyperalgesia develops in Ca(v)3.1-deficient and wild-type but not in Ca(v)3.2-deficient male and female mice. We also show that T-channels are required for the initiation, but not maintenance, of acid-induced chronic muscle pain. Blocking T-channels using ethosuximide prevented chronic mechanical hyperalgesia in wild-type mice when administered intraperitoneally or intracerebroventricularly, but not intramuscularly or intrathecally. Furthermore, we found an acid-induced, Ca(v)3.2 T-channel-dependent activation of ERK (extracellular signal-regulated kinase) in the anterior nucleus of paraventricular thalamus (PVA), and prevention of the ERK activation abolished the chronic mechanical hyperalgesia. Our findings suggest that Ca(v)3.2 T-channel-dependent activation of ERK in PVA is required for the development of acid-induced chronic mechanical hyperalgesia.</P>
Gap-flow patterns behind twin-cylinders at low Reynolds number
Shun Chang Yen,Chien Ting Liu 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.11
The flow structures, drag coefficients (Cd) and vortex shedding characteristics around a single square cylinder and twin side-by-side square cylinders were experimentally investigated with various Reynolds numbers (Re) and gap ratios (g*) in a vertical water tunnel. The Reynolds number (Re) and gap ratio (g*) were 178 < Re < 892 and 0 ≤ g* ≤ 2.5, respectively. The flow patterns and vortex shedding frequency were determined using the particle tracking flow visualization (PTFV). The flow structures, velocity properties, and drag coefficients were calculated using the particle image velocimetry (PIV). The topological flow patterns of vortex evolution processes were plotted and analyzed based on critical point theory. Furthermore, the flow structures behind twin side-by-side square cylinders were classified into three modes — single vortex-street mode, gap-flow mode and couple vortex-streets mode. The maximum Cd occurred in the single vortex-street mode, and the minimum Cd occurred in the gap-flow mode. The highest Strouhal number (St) occurred in the single vortex-street mode, and the lowest St occurred in the gap-flow mode.
Numerical investigation into dynamic behavior of adjustable preload double-nut ball screw
Chuen-Ren Wang,De-Shin Liu,Chien-Hsun Huang,Ting-Nung Shiau 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.10
The dynamic behavior of a double-nut ball screw was investigated by means of ABAQUS 6.13© simulations based on a threedimensional model. The validity of the numerical model was demonstrated by comparing the simulation results obtained for the reaction force and torque acting on the flange of the nut with the experimental results. We found that the two sets of results deviated by no more than 5.87% given a screw rotating speed of 100 rpm. Simulations were performed to investigate the effects of the spacer width, screw rotating speed, steel ball radius and axial force on the torque acting on the nut flange. The results show that the torque increases with an increasing spacer width due to an increasing preload force. Moreover, the torque increases as the screw rotating speed increases to 700 rpm, but decreases at higher rotating speeds due to a greater centrifugal force. Ball wear prompts a reduction in the preload force and thus reduces disproportionately the torque acting on the flange following extended operation. For higher axial loads (> 100 N), the torque remains approximately constant during run-in (0.025~0.2 s). However, for lower loads, notable fluctuations in the torque occur.
Sun, Hainan,Xu, Xiaomin,Hu, Zhiwei,Tjeng, Liu Hao,Zhao, Jie,Zhang, Qin,Lin, Hong-Ji,Chen, Chien-Te,Chan, Ting-Shan,Zhou, Wei,Shao, Zongping The Royal Society of Chemistry 2019 Journal of Materials Chemistry A Vol.7 No.16
<P>If different active sites in a catalyst have optimal binding to different reaction intermediates and short reaction paths among them, they may work cooperatively to enhance the oxygen evolution reaction (OER) activity. Based on this design principle, in this study, we start with a B-site ordered double perovskite Sr2FeMoO6−δ with poor OER activity as the host material to fulfill the requirement of a short pathway, and then, replace Mo with Ni and Fe with Co to optimize the synergistic interplay of the multi-active sites. Replacing Mo with Ni indeed dramatically enhances the OER activity and structural/operating stability. Further improvement in OER performance is realized by partial substitution of Fe with Co, leading to the development of a material with the nominal composition of Sr2Fe0.8Co0.2Mo0.65Ni0.35O6−δ, which outperforms the noble metal oxide IrO2 and is better than most of the electrocatalysts developed based on a single descriptor, such as Ba0.5Sr0.5Co0.8Fe0.2O3−δ (eg occupancy close to unity), PrBaCo2O5+δ (O 2p-band center relative to the Fermi level), and La0.5Sr0.5CoO3−δ (charge-transfer energy) in many aspects. As a universal method, combined structural and compositional tuning to create a cooperative effect among different active sites for intermediate adsorption and reaction in an ordered structure may provide a new way for the design of superior electrocatalysts for various applications.</P>