Ultrathin Perpendicular RE-TM Films with Low Coercivity and Low Magnetization on the Application of STT-RAM

Lin-Xiu Ye,Ching-Ming Lee,Jhih-Wei Syu,Wen-Jaun Chen,Te-ho Wu 한국자기학회 2008 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Electrospun Polyphenylquinoxaline Ultrafine Non-woven Fibrous Membranes with Excellent Thermal and Alkaline Resistance: Preparation and Characterization

Chen-yu Guo,Lu-meng Yin,Jin-gang Liu,Xin-ke Wang,Na Zhang,Lin Qi,Yan Zhang,Xiao Wu,Xiu-min Zhang 한국섬유공학회 2019 Fibers and polymers Vol.20 No.12

A series of polyphenylquinoxaline (PPQ) ultrafine non-woven fibrous membranes have been first successfullyprepared via the electrospinning procedure with the soluble PPQ solutions as the starting materials. For this purpose, variousorgano-soluble PPQ resins were synthesized via the one-step high temperature polycondensation procedure from thearomatic ether-bridged bis(α-diketone) and bis(o-diamine) monomers. Flexible ether linkages and pendant bulky phenylsubstituents endowed the PPQ resins good solubility in polar aprotic solvents. The high-molecular-weight PPQ resins weredissolved in N-methyl-2-pyrrolidone (NMP) to afford the PPQ electrospinning solution except PPQ-Ia derived from 4,4'-oxydibenzil (ODB) and 3,3'-diaminobenzidine (DAB) due to the limited solubility in the solvent. All the derived PPQultrafine non-woven fibrous membranes maintained good structure integrity after hydrolysis aging either at room temperature(25 oC) for 72 h or at refluxing temperature (100 oC) for 24 h in an aqueous sodium hydroxide (NaOH) solution at a solidcontent of 20 wt%. Comparatively, the polyimide (PI) reference electrospun membrane (PI-ref) derived from 1,2,4,5-pyrromellitic anhydride (PMDA) and 4,4'-oxydianiline (ODA) lost its original structure only after boiling in the same NaOHsolution within 3 h. In addition, the developed PPQ ultrafine non-woven fibrous membranes exhibited good thermal stabilitywith the 5 % weight loss temperatures (T5%) higher than 555.0 oC in nitrogen and glass transition temperatures (Tg) in therange of 248.1-266.1 oC, respectively.

Design and Implementation on Spatial Science and Technology Information Database of CSI

Chen, Xiu Wan,Deng, Zheng Quan,Lu, Zhi Gao,Ma, Jia,Lin, Jia Yuan,Zhang, Wen Jiang,Luo, Tianfu,Liu, Baofu 대한원격탐사학회 2000 International Symposium on Remote Sensing Vol.16 No.1

Remote Sensing technology, which is characterized by producing imagery an multi-platform, different temporal and spatial resolution, has greatly improved mankind's capability of acquisition, processing and application of spatial information. The increase of spatial data sources and the development, applications and industrialization of spatial information technology are urging the need of spatial data sharing and exchanging. Based an a brief introduction an the China Spatial Information Network (CSI) and its database system, the CSI Spatial Science and Technology Information Database (SSTID) management system was designed and implemented in this paper.

XIST Induced by JPX Suppresses Hepatocellular Carcinoma by Sponging miR-155-5p

Xiu-qing Lin,Zhi-ming Huang,Xin Chen,Fang Wu,Wei Wu 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.7

Purpose: The influence of X-inactive specific transcript (XIST) and X-chromosome inactivation associated long non-coding RNAs (lncRNAs) just proximal to XIST (JPX) on hepatocellular carcinoma (HCC) remains controversial in light of previous reports, which the present study aimed to verify. Materials and Methods: The DIANA lncRNA-microRNA (miRNA) interaction database was used to explore miRNA interactions with JPX or XIST. JPX, XIST, and miR-155-5p expression levels in paired HCC specimens and adjacent normal tissue were analyzedby RT-qPCR. Interaction between XIST and miR-155-5p was verified by dual luciferase reporter assay. Expression levels of miR-155-5p and its known target genes, SOX6 and PTEN, were verified by RT-qPCR and Western blot in HepG2 cells with or withoutXIST knock-in. The potential suppressive role of XIST and JPX on HCC was verified by cell functional assays and tumor formationassay using a xenograft model. Results: JPX and XIST expression was significantly decreased in HCC pathologic specimens, compared to adjacent tissue, which correlated with HCC progression and increased miR-155-5p expression. Dual luciferase reporter assay revealed XIST as a direct target of miR-155-5p. XIST knock-in significantly reduced miR-155-5p expression level and increased that of SOX6 and PTEN, while significantly inhibiting HepG2 cell growth in vitro, which was partially reversed by miR-155-5p mimic transfection. JPX knock-in significantly increased XIST expression and inhibited HepG2 cell growth in vitro or tumor formation in vivo in a XIST dependent manner. Conclusion: JPX and XIST play a suppressive role in HCC. JPX increases expression levels of XIST in HCC cells, which suppresses HCC development by sponging the cancer promoting miR-155-5p.

중국과 일본 대학생의 거시경제학 이해력 비교 연구

인시유얀 ( Xiu Yan Yin ),쿠이얀 ( Yan Cui ),린지마이 ( Jie Mei Lin ),린첸 ( Chen Lin ) 한국경제교육학회 2013 경제교육연구 Vol.20 No.2

This paper presents a comparison of the understanding in college macroeconomics between China and Japan and further analyzes the influencing factors of the understanding in macroeconomics. It is proved by means of statistical analysis and econometric models. The author administered the macroeconomic TUCE-4 test (The Test of Understanding in College Economics, fourth edition) developed by the U.S. National Council on Economic Education, for both Chinese and Japanese undergraduate students. The results could be summarized as follows: First, the students from both countries obtained high scores for the ‘explicit application’ category and furthermore the Chinese students obtained higher scores on individual question item and higher composite scores than the Japanese students. Second, the effect of university prestige and the effect of year in school are significant in the students` understanding of macroeconomics in both countries while the effect of learning experience of macroeconomics is not significant. Third, the differences between China and Japan were found in the effect of major and the effect of gender.

Pokemon Inhibits Transforming Growth Factor β-Smad4-Related Cell Proliferation Arrest in Breast Cancer through Specificity Protein 1

Ling Chen,Jing Zhong,Jiang-Hua Liu,Duan-Fang Liao,Ying-Ying Shen,Xiao-Lin Zhong,Xiao Xiao,Wen-Jun Ding,Xiu-Da Peng,Wei Xiong,Xu-Yu Zu 한국유방암학회 2019 Journal of breast cancer Vol.22 No.1

Purpose: Pokemon, also known as ZBTB7A, belongs to the POZ and Krüppel (POK) family of transcription repressors and is implicated in tumor progression as a key proto-oncogene. This present study aimed at determining the mechanism by which Pokemon inhibits transforming growth factor β (TGFβ)-Smad4 pathway-dependent proliferation arrest of breast cancer cells via specificity protein 1 (SP1). Methods: Over-expressing plasmid or small interfering RNA (siRNA) transfection was used to regulate Pokemon levels. The EdU incorporation assay, MTS assay, and clone formation were used to identify the inhibitory effect of Pokemon siRNA on cell proliferation. Quantitative real-time polymerase chain reaction assay confirmed that Pokemon deletion inhibited the expression of proliferation-associated genes. The dual-luciferase reporter assay, electrophoretic mobility shift assay, and co-immunoprecipitation assay were used to analyze binding between Pokemon, Smad4, and SP1. Results: Pokemon deletion induced proliferation arrest of breast cancer cells and inhibited the expression of proliferation-associated genes, especially Smad4. Pokemon bound with SP1 to interdict Smad4 promoter activity. Information on clinical samples was obtained from The Cancer Genome Atlas data, in which the Pokemon mRNA levels showed a negative correlation with Smad4 levels in different subtypes of breast cancer in two independent datasets. Conclusion: We demonstrated that Pokemon binds to SP1 to down-regulate Smad4 expression, thereby promoting proliferation of breast cancer cells. This suggests that Pokemon is a potential TGFβ-signaling participant in breast cancer progression.

Discrimination of Chinese Baijiu grades based on colorimetric sensor arrays

Hao Lin,Wen-cui Kang,Hong-juan Jin,Zhong-xiu Man,Quansheng Chen 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.8

In this study, a novel colorimetric sensor arraybased on chemo dyes including porphyrins and pH indicatorswere developed to analyse the volatile organiccompounds of Chinese Baijiu with different grades. Ethylacetate, ethyl butyrate and ethyl caproate appeared bysignificantly different concentration in different Baijiugrades measuring by gas chromatography and mass spectrometryand they were chosen as characteristic volatileorganic components. The olfactory visualization systembased on colorimetric sensor arrays was used to identifydifferent Baijiu grades. The data were processed bybuilding the principle components analysis, linear discriminantanalysis and K-nearest neighbor classificationmodels with the results of sensory evaluation and olfactoryvisualization system. This work presents a new-style colorimetricsensor using sensitive chemo dyes which hassignificant potential in quantitative analysis of volatileorganic compounds, afterwards identifying different gradesof Baijiu.

Tumor-derived CD4+CD25+ Tregs Inhibit the Maturation and Antigen-Presenting Function of Dendritic Cells

Du, Yong,Chen, Xin,Lin, Xiu-Qing,Wu, Wei,Huang, Zhi-Ming Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

CD4+CD25+regulatory T cells (Tregs) play a key role in regulation of immnue response and maintenance of self-tolerance. Studies have found Tregs could suppress tumor-specific T cell-mediated immune response and promote cancer progression. Depletion of Tregs can enhance antitumor immunity. Dendritic cells (DCs) are professional antigen-presenting cells and capable of activating antigen-specific immune responses, which make them ideal candidate for cancer immunotherapy. Now various DC vaccines are considered as effective treatment for cancers. The aim of this study was to evaluate variation of Tregs in BALB/C mice with hepatocellular carcinoma and investigate the interaction between tumor-derived Tregs, effector T cells (Teff) and splenic DCs. We found the percentages of Tregs/CD4+ in the peripheral blood of tumor-bearing mice were higher than in normal mice. Tumor-derived Tregs diminished the up-regulation of costimulatory molecule expression on splenic DCs, even in the presence of Teff cells and simultaneously inhibited IL-12 and $TNF-{\alpha}$ secretion by DCs.

Calculation of Life-Time Death Probability due Malignant Tumors Based on a Sampling Survey Area in China

Yuan, Ping,Chen, Tie-Hui,Chen, Zhong-Wu,Lin, Xiu-Quan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

Purpose: To calculate the probability of one person's life-time death caused by a malignant tumor and provide theoretical basis for cancer prevention. Materials and Methods: The probability of one person's death caused by a tumor was calculated by a probability additive formula and based on an abridged life table. All data for age-specific mortality were from the third retrospective investigation of death cause in China. Results: The probability of one person's death caused by malignant tumor was 18.7% calculated by the probability additive formula. On the same way, the life-time death probability caused by lung cancer, gastric cancer, liver cancer, esophageal cancer, colorectal and anal cancer were 4.47%, 3.62%, 3.25%, 2.25%, 1.11%, respectively. Conclusions: Malignant tumor is still the main cause of death in one's life time and the most common causes of cancer death were lung, gastric, liver, esophageal, colorectal and anal cancers. Targeted forms of cancer prevention and treatment strategies should be worked out to improve people's health and prolong life in China. The probability additive formula is a more scientific and objective method to calculate the probability of one person's life-time death than cumulative death probability.

Integrin-linked Kinase Functions as a Tumor Promoter in Bladder Transitional Cell Carcinoma

Wang, De-Lin,Lan, Jian-Hua,Chen, Liang,Huang, Biao,Li, Zeng,Zhao, Xiu-Min,Ma, Qiang,Sheng, Xia,Li, Wen-Bin,Tang, Wei-Xue Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

The aim of this study was to elucidate the role of the integrin-linked kinase (ILK) gene in development of human bladder transitional cell carcinoma (BTCC). Expression of ILK protein and ILK mRNA in 56 cases of human BTCC tissue and in 30 cases of adjacent normal bladder tissue was detected by immunohistochemistry S-P and reverse transcription polymerase chain reaction (RT-PCR), respectively. Four specific miRNA RNAi vectors targeting human ILK were synthesized and transfected into BIU-87 cells by liposome to obtain stable expression cell strains. The influence of ILK on proliferation of BTCC was detected by MTT, FCM on athymic mouse tumorigenesis. The positive rate of ILK protein in BTCC tissue (53.6%) was much higher than adjacent normal bladder tissue (10.0%) (p<0.05). Similarly, expression of ILK mRNA in BTCC tissue ($0.540{\pm}0.083$) was significantly higher than in adjacent normal bladder tissue ($0.492{\pm}0.070$) (p<0.05). MTT showed that the proliferation ability of miRNA-ILK transfected group was clearly decreased (p<0.05), the cell cycle being arrested in G0/G1-S, an tumorigenesis in vivo was also significantly reduced (p<0.05). ILK gene transcription and protein expression may be involved in the development of BTCC, so that ILK might be the new marker for early diagnosis and the new target for gene treatment.