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Application of Green Collaboration Operation on Network Industry
Ruey-Shun Chen,Yeh-Cheng Chen,Chi Nung Chu,Hung-Min Sun,Ling-Chi Chen,Chia-Chen Chen 한국정밀공학회 2015 International Journal of Precision Engineering and Vol.2 No.1
Traditional information system and managerial mechanism cannot meet the new environment protection regulations; therefore, a new solution must be set up, else it may run the risk of losing the market and the value of product brand.This research focuses on the solutions provided by the network and communication industry, manufacture of the green products, and the establishment of a Web-based green collaboration management system, which incorporates the environment protection requests into the product development and green supply chain activities. There are three goals: (1) For the design of green products, green components and product management are set up for the purpose of de-toxin and ease of disassemble; (2) For the green supply chain, the management of hazardous substances, product recycle and disassemble are set up; (3) For the product recycling management, the recycling information is feedback for the product update and collaboration operation. The result of research can provide information for the integration of workflow and information system currently in use, provide RoHS and WEEE management solutions, and set up green collaboration information system, so that green products, brand leadership, and environment protection endeavor can be assured.
Wei-Che Lin,Wen-Chieh Chen,Pei-Wen Wang,Yi-Chia Chan,Yen-Hsiang Chang,Harn-Shen Chen,Szu-Tah Chen,Wei-Chih Chen,Kai-Lun Cheng,Shun-Yu Chi,Pi-Ling Chiang,Chen-Kai Chou,Feng-Fu Chou,Shun-Chen Huang,Feng 대한초음파의학회 2023 ULTRASONOGRAPHY Vol.42 No.3
Radiofrequency ablation (RFA) is a minimally invasive management strategy that has been widely applied for benign and recurrent malignant thyroid lesions as an alternative to surgery in Taiwan. Members of academic societies for specialists in interventional radiology, endocrinology, and endocrine surgery collaborated to develop the first consensus regarding thyroid RFA in Taiwan. The modified Delphi method was used to reach a consensus. Based on a comprehensive review of recent and valuable literature and expert opinions, the recommendations included indications, pre-procedural evaluations, procedural techniques, post-procedural monitoring, efficacy, and safety, providing a comprehensive review of the application of RFA. The consensus effectively consolidates advice regarding thyroid RFA in clinical practice for local experts.
Effects of Plant Secondary Metabolites(flavone) on Foraging Behavior of Sheep
Ling Wang,Deli Wang,Xiao Shun,Guowei Chen 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
Ingestion of plant secondary metabolites (PSMs) presents a major challenge to mammalian herbivores. We investigated the relationship between PSM concentrations in the diet and feeding patterns in sheep fed diet containing flavone extracted from Apocynum venetum. Results showed that the flavone concentrations significantly influenced food intake by sheep. With the concentration of flavone in diet increase, sheep can regulate their intake of PSM within limits that are tolerable.
Qing-Ling Wang,Shao-Chen Sun,Xing-Wei Liang,Sung-Hyun Lee,Nam-Hyung Kim,Xiang-Shun Cui 한국동물번식학회 2012 Reproductive & Developmental Biology(Supplement) Vol.36 No.2s
It is well established that mammalian cumulus cell (CC) expansion requires BMP15 (bone morphogenetic protein bone morphogenetic protein 15) and GDF9 (growth differentiation factor 9). However, the mechanisms of the factors in CC expansion are largely unclear. This study was conducted to examine the two paracrine factors and their receptor SMAD intracellular signaling mechanism of mediating porcine CC expansion and oocyte maturation, and to compare COCs (Cumulus-oocyte complexes) maturation to DOs (Denuded oocytes). COCs and DOs were in vitro matured in medium with FSH, LH and TGFB superfamily antagonists. Our results showed that the expansion of COCs was unaffected by addition of GDF9 and BMP15 recombinant protein, but cumulus cell proliferation and DOs maturation rate were enhanced. The mRNA expressions of SMAD receptor confirmed that oocytes secreted factors that activate SMAD3,4 and SMAD1 in granulosa cells and oocytes, but unaffected SMAD2. Treatment of COCs with a SMAD2/3 phosphorylation inhibitor (SB431542) inhibited CC expansion and expression of TNFAIP6. SB431542 also was revealed to inhibit DOs maturation. The activation of CC SMAD signaling by oocytes, and the requirement of SMAD2/3 signaling for expansion and oocyte maturation were studied in pig. Nonetheless, porcine oocyte maturation without SMAD2/3 signaling is likely to be needed for optimal matrix formation, but also BMP15 and GDF9 is likely to be needed in oocyte.
Doxorubicin Induces Early Embryo Apoptosis by PARP in Mice
Qing-Ling Wang,Shao-Chen Sun,Sung-Hyun Lee,Xiang-Shun Cui,Nam-Hyung Kim 한국동물번식학회 2012 Reproductive & Developmental Biology(Supplement) Vol.36 No.2s
Doxorubicin, a widely used chemotherapeutic agent, were found rapidly undergo morphological and biochemical changes via discrete effector signaling pathways consistent with the occurrence of apoptosis of oocyte. In this report, we elucidated the molecular requirements for actions of this drug in early embryos. Poly (ADP-ribose) polymerase (PARP), a DNA repair enzyme, and its homologues have recently been shown in female oocyte cells. However, the cleavage of PARP by caspase-3 inactivates it and inhibits PARP's DNA-repairing abilities. Cleaved PARP (cPARP) may be considered a marker of apoptosis. Doxorubicin inhibited the early embryo development, but the treatment could still reach the BL (blastocyst) stage that suggested that involved in DNA synthesis and repaired progress. Herein, the higher expression of PARP family shown especially in 2, 4 cell stagy. There was evidence of expression of Caspase3 and Bcl2l1 during embryogenesis (2 cell, 4 cell, morula and BL stage), suggesting that modulations of apoptosis-related genes and PARP were cause by DXR. Furthermore, the effect of doxorubicin on early embryo development was assessed different stage rates, and apoptosis index also conformed doxorubicin modulate embryo development by regulating apoptosis-related genes and PARP family genes. In conclusion, Doxorubicin blocked pre-implantation development in early mouse embryos by altering apoptosis-related gene expression and inactivating DNA repair by Parp.
Actin nucleator Arp2/3 complex is essential for mouse preimplantation embryo development
Sun, Shao-Chen,Wang, Qing-Ling,Gao, Wei-Wei,Xu, Yong-Nan,Liu, Hong-Lin,Cui, Xiang-Shun,Kim, Nam-Hyung CSIRO Publishing 2013 Reproduction, fertility, and development Vol.25 No.4
<P> The Arp2/3 complex is a critical actin nucleator, which promotes actin assembly and is widely involved in a diverse range of actin-related processes such as cell locomotion, phagocytosis and the establishment of cell polarity. Previous studies showed that the Arp2/3 complex regulates spindle migration and asymmetric division during mouse oocyte maturation; however, the role of the Arp2/3 complex in early mouse embryo development is still unknown. The results of the present study show that the Arp2/3 complex is critical for cytokinesis during mouse embryo development. The Arp2/3 complex was concentrated at the cortex of each cell at the 2- to 8-cell stage and the peripheral areas of the morula and blastocyst. Inhibition of the Arp2/3 complex by the specific inhibitor CK666 at the zygote stage caused a failure in cell division; mouse embryos failed to undergo compaction and lost apical-basal polarity. The actin level decreased in the CK666-treated group, and two or more nuclei were observed within a single cell, indicating a failure of cell division. Addition of CK666 at the 8-cell stage caused a failure of blastocyst formation, and CDX2 staining confirmed the loss of embryo polarity and the failure of trophectoderm and inner cell mass formation. Taken together, these data suggest that the Arp2/3 complex may regulate mouse embryo development via its effect on cell division. </P>
Doxorubicin induces early embryo apoptosis by inhibiting poly(ADP ribose) polymerase.
Wang, Qing-Ling,Sun, Shao-Chen,Han, Jemesbond,Kwak, Yong-Chul,Kim, Nam-Hyung,Cui, Xiang-Shun Dr. J.G. Delinassios 2012 In vivo Vol.26 No.5
<P>The effect of Doxorubicin, a widely used chemotherapeutic agent, on early mouse embryonic development has not been previously characterized.</P>