Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants

Che´rif Rabhi,Guillaume Arcile,Le´on Cariel,Christine Lenoir,Je´rome Bignon,Joanna Wdzieczak-Bakala,Jamal Ouazzani 한국식품영양과학회 2015 Journal of medicinal food Vol.18 No.9

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex® technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.

제주 우수 육상경기 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe t h e annual effect of training of periodically anaerobic and aerobic motor ability for Che-Ju representive team of elementary, middle and high school athletes. first. the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events. second, individually fitness. scientific analysis. prescription. proper management of athlete will be necessary to apply. In addition to physiology aspect, it is essential to consider sport biomechanics. sport psychology when we prescribe specific events and necessary approach in demension coach-athlete-researcher for individual.

제주 우수 수영 선수들의 년중 훈련효과 분석 및 처방

김철원,임상용,김승곤,오만원,김성찬,이창준,남사웅,이세형,류재청 濟州大學敎 體育科學硏究所 1996 체육과학연구 Vol.2 No.-

The study was undertaken to analysis, evaluate, and prescribe the annual effect of training of periodically anaerobic and erobic motor ability for Che-Ju representive team of elementary, middle and high school athletes, first the performance can be obtained when it was prescribed proper training after analysis of physical fitness by each events, second individually fitness scientific analysis. prescription. proper management of athlete will be necessary to apply.

의료소비자의 관계혜태 지각이 관계의 질 및 행동의도에 미치는 영향

허철선(Che이-Seon Heo),유광우(Kwang-Woo Yoo) 한국무역연구원 2014 무역연구 Vol.10 No.1

Medical institutions are important to develop and maintain enduring relationship with medical service conswners. So, this research aims to find out the effect of medical service conswners perception of relational benefits on relationship quality and behavioral intention. On the basis of the literature review, the research model is established. This research has been done through the survey utilizing medical service consumers in Gangwondo, and the effective 368 questionnaires are tested for the research model. The main findings are as follows. First, among 5 key dimensions of relational benefits, psychological, customization, economic, and information benefits except social benefits have significant effects on relationship satisfaction. Also, medical institutions type and medical service consumers type as moderating variables are included concurrently, and the significant differences are found in other 4 benefits except relationship between social benefits and relationship satisfaction. Second, relationship satisfaction relates positively to relationship commitment and behavioral intention. But the normative commitment, one of 3 key dimensions of relationship commitment, has no significant effects on recommendation to others. Third, the revisit intention has significant effect on recommendation to others. Finally, the findings reveal that the overall goodness fit index of the model is comparatively good and model set in this research is significant. At the end of the research, managerial implications, limitations and future research directions are suggested.

의료 화상을 위한 전처리 필터들의 특성에 관한 연구

강명아,최종주,정종필,정채영,정남채 조선대학교 기초과학연구소 1997 自然科學硏究 Vol.20 No.1

There has been no fixed rule of pre-processing course required to do image processing that it was barely possible to find the proper pre-processing course, only to process with experience till now. In this paper, lots of application method of pre-processing algorithm, only available by the non-typified and experiential method, shall quantify and the algorithm method of algorithm according to the rule shall calculate the frequency of the value of each pixel gray level and the histogrm of the image. And then average it to all pixel number and finally set a high-ranking or optional % standardized by the average value in teh standard value. The result of a experiment showed the Median filter is superior to the Mean filter in all image of the smoothing filter. The sobel filter extracted feature. The laplacian filter presented sectional feature which not showed in original image.

근로 장애인의 직무만족도에 영향을 주는 심리사회적 변인에 관한 연구

이채식,김명식 한국장애인고용공단 고용개발원 2012 장애와 고용 Vol.22 No.1

This study investigated exploratorily the effect of disability acceptance, job stress, motivation for work, and job attitude influencing the job satisfaction of the working people with disabilities. And it tried to search and suggest the interventions of policy and practice for enhacing their job satisfaction. It used and analyzed the data of 'The 3rd Survey of Employment of the Disabled(2011)" by Korea Employment Promotion Agency for the Disabled. Main results are as follows: The disability acceptance positively influenced the job satisfaction and 'work and interpersonal relation job stress' negatively the job satisfaction, and 'no option' negatively did. The more they perceive their work according with their job aptitudes, the more they perceive their job satisfactions. Therefore its main results will be seem to be used as basic data for suggesting the ways of policy and practice for the disabled. 본 연구는 근로 장애인의 직무만족에 영향을 미치는 요인을 장애수용, 직무 스트레스, 근무동기, 직무적성 등 심리사회적인 변인을 중심으로 구분하여 탐색적으로 검증하고, 본 연구결과를 토대로 근로 장애인의 직무만족도를 높일 수 있는 정책적ㆍ실천적 개입방안을 제시하는데 그 목적이 있다. 이러한 요인을 규명하기 위해 한국장애인고용촉진공단에서 실시한 ‘제3차 장애인고용패널조사(2011)’ 데이터를 활용하였다. 분석결과 장애수용이 직무만족에 긍정적 영향을 주는 것으로 나타났고, 직무스트레스에서는 ‘일과 대인관계’가 직무만족에 부정적 영향을 주는 것으로 나타났다. 또한 근무동기에서는 ‘대안이 없어서’가 직무만족에 부정적 영향을 주며, 직무적성이 직무만족에 주는 영향에서는 직무적성이 일치한다고 지각할수록 직무만족에 긍정적 영향을 주는 것으로 나타났다. 따라서 본 연구 결과는 향후 근로 장애인의 직무만족을 높일 수 있는 정책적ㆍ실천적 개입 방향을 설정하는 데 있어서 중요한 기초자료로 활용될 수 있을 것이다.

군산시 지하수의 특성에 대한 연구

장재철,성금수,김동원 군산대학교 기초과학연구소 2000 基礎科學硏究 Vol.15 No.-

The purpose of this study is to investigate the pollution characteristics of groundwaters in Kansan city. Volatile organic compounds such as TCE(tri-choroethylene), PCE(tetruchloroethylene), 1,1,1-trichloroethane, THM(trihalo-methane), dichloromethane, pesticides such as diazinon, parathion, malathion, toxic inoganic matters such as As, Hg, Se, Cd, Al, Cr6+, oder, taste and phenol were not detected in the groundwaters. Mean values of groundwater pollution indicators were bellow drinking-water standards, but Bacteria, Total Coliforms, Pb, Mn, NO3-N and NH3-N, total solid and pH exceeded a little in some samples.

정신지체인의 적응행동 요인이 직업유지기간과 이직경험횟수에 미치는 영향

이채식,이성규 한국사회복지정책학회 2005 사회복지정책 Vol.21 No.-

본 연구는 정신지체인의 적응행동(개념적·사회적·직업적 기술 및 사회적 지지) 요인이 직업유지기간과 이직경험횟수에 어떠한 영향을 미치는지 실증적으로 밝히는데 있다. 분석결과를 요약하면 첫째, 직업유지기간에 유의한 영양을 주는 변인들은 일반적 특성 중에서 직종, 종업원수, 장애인수, 작업지도원 배치, 사회적 기술요인 중에서 안전능력, 금전관리능력, 직업적 기술 요인 중에서 직업생활태도, 작업도구수행능력, 직업적 행동특성, 그리고 사회적 지지요인 중에서 전문가 지지 등으로 나타났으며, 요인간의 상대적 크기는 직업적 기술요인이 가장 높게 나타났다. 둘째, 이직경험횟수에 유의한 영향을 주는 변인들은 일반적 특성 중에서 월평균 임금, 복리후생시설수, 직종, 개념적 기술요인 중에서 수개념, 직업적 기술요인 중에서 직업생활태도, 직업적 행동특성 등으로 나타났으며, 요인간의 상대적 크기는 직업적 기술 요인이 가장 높게 나타났다. 이러한 연구결과는 정신지체인의 직업유지기간을 높이는데 있어서 개념적, 사회적 기술보다는 사업체 현장에서 작업자에게 실질적으로 요구되는 작업기술과 관련된 직업적 기술이 중요함을 알 수 있다. 따라서 정신지체인에 대안 직업재활은 작업현장에서 실제적으로 적용할 수 있는 직업기술과 관련된 제도와 서비스 체계가 중요하다는 것이 실증적으로 입증되었다. This study examined practically the effects of adaptation behavior factors (conceptual skills, social skills, occupational skills and social support) of people with mental retardation on the duration of job tenure and the number of separation. To summary the result of analysis, firstly, the variables which influence the duration of job tenure significantly are the number of employees, the number of people with disabilities and the existence of work guide from general characteristics factors; safety managing abilities and money managing abilities from social skills factors; job attitude, tool handling skills and job-related behavioral characteristics from occupational skills factors; and professional support from social support factors. The occupational skills factors have relatively highest influence among other factors. Secondly, the variables which influence the number of separation significantly are average monthly wage, the number of welfare facilities and the type of occupation from general characteristics factors; number concept from conceptual skills factors; and job attitude, and job-related behavioral characteristics from occupational skills factors. The occupational skill factors have relatively highest influence among other factors. These results show that in extending the duration of job tenure of people with mental retardation, the occupational skills, which is related to the work skill required practically to the worker in the work field, are more important than the conceptual skills and social skills. Consequently, it is proved that in vocational rehabilitation for the people with mental retardation, the organization and the service system is important, which is related to the work skill applicable practically to the work field.

建築의 立面表現과 記號論 : 주택의 입면경관표현에 관한 기호론적 분석

林采震 홍익대학교환경개발연구원 1994 환경개발연구논문집 Vol.1 No.-

The purpose of this study is to find out whether there is a sign system in suburban housing elevation. The form of Housing functions not only for use but also for sign which has effect on [mentality of human life]. However, in a recently according as the variety of construction become divergent the type of housing stops to be vigible and disorder among the visual elevations disturbs the goal of elevational view of housing planning because planning is generally consisting in a conventional code which provides a proper signification for a type. Therefore, this study tries to make up a code through analyzing the correlations among visual aspects or collected from 20 individual houses. As a result of quantifying analysis based on matrix of two characteristic, the author concludes that several types are visible on two significant units, i.e. [site plan] and [Facade].

만경강하구역에 서식하는 풀망둑어(Acanthogobius hasta)중의 중금속함량에 관한 연구

장재철,권용훈,김경현 群山大學校 1997 論文集 Vol.24 No.-

만경강 하구에 서식하는 풀망둑어(Acanthogobius hasta)를 기관별(지느러미, 아가미, 뼈, 폐 근육, 머리)로 7가지의 중금속을 분석하였다. 그 결과 Cd, Cr, Cu, Zn, Mn, As 등이 지느러미>아가미>뼈>폐>머리>근육 순으로 높게 나타났고, 반면 7가지의 중금속중에 Pb Hg 미검출 되었다. Cd, Cu, Zn, As Cr은 지느러미 뼈 머리 부위에서, 폐 아가미부위에 비해 전반적으로 높게 나타났다. 모든 중금속들은 다른 기관보다도 지느러미와 뼈에 많은 량을 함유하고 있음을 알았다. The concentration of 7 heavy metals(Pb, Hg, Cu, Cr, Zn, Mn, Cd, and As)were measured in the tisseus(head, bone, muscle, lung, gill, pinna)of the Acanthogobius hasta of Man-kyung estuary. The order of mean value of cadimium, copper, zinc and manganese content in the five parts were shown as pinna>gill>bone>lung>head respectively. The other side among the seven heavy metal contents did not show lead and mercury. Cd, Cu, Zn, As, Cr, Mn were detected higher in the part of pinna, bone and head than lung, gill.