수영선수의 스포츠 가치관 연구

최영옥,이병두 韓國體育大學校附屬 體育科學硏究所 1990 韓國體育大學校附屬 體育科學硏究所論文集 Vol.9 No.1

This study was undertaken to investigate to swimmer's value orientation toward sport, thereby examining value differences due to school level and gender. 101 female high school swimmers(M age=16.3yrs), 149 male high school swimmers(M age=16.7yrs), 34 female college level swimmers(M age=19.8yrs) and 31 male college level swimmers(M age=22.3yrs) reported their value systems on Sport Value Orientation Inventory. The data relative to the value orientation toward sport were analyzed using frequencies, % and X??. The implications of the study are as follows; 1. At high school level, male swimmers were more concerned with moral cultivation, spiritual strength, steady effort, good manners and hard training, and less concerned with sacrifice for team's success than were their female counterparts. 2. At college levels, there was a statistically significant difference between males and female in steady effort. Males and females together valued privacy, spiritual spirit, moral cultivation and good manners, and were less concerned with individualism. 3. High school swimmers exceeded college level swimmers in valuing sport nationalism. 4. Male high school swimmers were more likely to value spiritual strength and hard training strongly than their counterparts at college level, while female swimmers were more concerned with hard training, sport-oriented life, good manners, athletic reward than female college level swimmers. These results show the need for additional empirical studies including the socializing fa ctors of somatotype, self-concept, family structure, reference group etc., which detail the role that sport plays in shaping values. Answer to these and other questions that lead to a more precise definition of the differences in value orientation of athletes will help sport psychologists and sociologists provide a clearer picture of the athletic environment and its influence.

몇 가지 전이금속, Ni(II) 및 Zn(II) 3,6-bis(2'-pyridyl)pyridazine 착 화합물들의 세포 독성효과

권병목,이정옥,최상운,성낙도 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

A series of cytotoxic activities (ED_(50)) in vitro against six human cancers (lung cancer, uterine cancer, skin cancer, brain cancer, colon cancer and adenocarcinoma) and their seventeen cell lines of 3,6-bis(2'-pyridyl)pyridazine, 1, 3,6-bis-(6'-methyl-2'-pyridyl)pyridazine, 2 and their transition metal, Ni(II), Cu(II) and Zn(II) complexes, 3~6 were measured. Particularly, the results revealed that the cytotoxic activities against the brain cancer cell line (SNB-19) and the colon cancer cell line (SW62) of bis-[3,6-bis-(6'-methyl-2'-pyridyl)pyridazine-k^(2)N^(2),N^(3)]chlorocopper(II)perchlorate, 4 were shown to be higher than that of the first generation anticancer agent, Cis-platin. 6종의 인체 암(폐암, 피부암, 결장암, 자궁암, 선암 및 뇌암)과 그의 17가지 세포주들에 대한 리간드 화합물 3,6-bis(2'­pyridyl)pyridazine(1)과 3,6-bis(6'-methyl-2'-pyridyl)pyridazine(2) 그리고 그들의 전이금속(Ni(II), Cu(II) 및 Zn(II)) 착 화합물들 (3~6)의 세포독성을 각각 측정하였다. 그 결과, 특히 Cu(II) 착화합물, bis-[3,6-bis-(6'-methyl-2'-pyridyl)pyridazine-k^(2)N^(2),N^(3)]chlorocopper(II)perchlorate (4)는 뇌암(SNB-19)과 결장암(SW-62) 세포주에 대하여 제1세대 항암제인 Cis-platin보다 높은 세포독성을 나타내었다.

玄蔘의 Saponin 成分 檢索 : on the Saponin of the Radix

남인숙,배병숙,최보향,최인수,최태수,김동언,김언주,정미영,조규옥 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

Crude saponin(100g) were obtained by extracting the radix(5kg) of Scrophalariae koraiensis Nakai. Crude saponin were positive in the Liebermann-Burchard test. We observed 5 sports by TLC using BuOH saturated with H_2O : ethyl acetate : water(4:1:5, upper phase) as solvent and 1% Ce(SO_4)_2 in 10% H_2SO_4 as a color former. We divided into 3 fractions by common column chromatography using BuOH saturated with H_2O : ethylacetate : water(4:1:5, upper phase) as solvent.

Malignant and borderline phyllodes tumors of the breast: a multicenter study of 362 patients (KROG 16-08)

Choi, Noorie,Kim, Kyubo,Shin, Kyung Hwan,Kim, Yumi,Moon, Hyeong-Gon,Park, Won,Choi, Doo Ho,Kim, Su Ssan,Ahn, Seung Do,Kim, Tae Hyun,Chun, Mison,Kim, Yong Bae,Kim, Suzy,Choi, Byung Ock,Kim, Jin Hee Springer-Verlag 2018 Breast cancer research and treatment Vol.171 No.2

Intraluminal High-Dose-Rate Brachytherapy for the Tumors of Gastrointestinal Tract

최병옥(Byung Ock Choi),최일봉(Ihl Bhong Choi),정수미(Su mi Chung),김인아(In Ah Kim),최명규(Myoung Gyu Choi),장석균(Suk Kyun Chang),신경섭(Kyeong Sub Shinn) 대한방사선종양학회 1995 Radiation Oncology Journal Vol.13 No.3

목적 : 위장관종양에 대한 고선량율 강내 방사선치료의 결과를 분석하고자 하였다. 방법 : 카톨릭의대 성모병원 치료방사선과에서는 1991년 2월부터 1993년 7월까지 18명의 수술을 할 수 없는 중증의 위장관종양 환자들(식도암-8, 직장암-10)을 대상으로 Iridium-192을 사용하여 원격조정 고선량율 강내 방사선치료에 대한 후향적 분석을 하였다. 연령 분포는 47-87세로, 평균 71세였다. 모든 환자들은 이전에 수술적 조작을 받은적이 없었고, 외부 방사선치료 이후 2주 이내에 고선량율 강내 방사선치료를 하였으며, 고선량율 강내 방사선치료의 일일 조사량은 3-5 Gy(3-4회/1주), 총 조사량은 12-20Gy로 평균 17Gy였다. 외부방사선 총 조사량은 41.4-59.4Gy로 평균 49.6Gy였다. 추적기간은 3개월에서 31개월이었고, 중앙추적기간은 19개월이었다. 결과 : 식도암에서 완전관해와 부분관해는 각각 38%로 같은 결과를 보였으며, 중앙 생존기간과 2년 생존율은 10개월과 13%였다. 직장암 10명 중 60%의 환자에서 부분반응을 보였으며, 완전반응은 없었지만, 모든 환자에서 현저한 증상개선을 보였다. 저자는 고선량율 강내 방사선 일일 조사량 및 총 조사량, 외부방사선 조사량이 국소반응율과 생존율에 미치는 영향을 분석, 조사하였다. 이 중, 고선량율 강내 방사선 일일 조사량 및 총 조사량이 직장암의 국소반응율에 가장 큰 영향을 미쳤으며, 이는 통계적 유의성을 보였다 (p<0.05). 식도암에서는 고선량율 강내 방사선 총 조사량이 국소반응율과 생존율에 각각 영향을 미쳤으나, 이는 통계적 유의성은 없었다. 또한, 외부방사선 조사량은 모든 환자에게서 국소반응율과 생존율에 영향을 미치지 않는 것으로 나타났다. 모든 환자들에게서 치료 후 현저한 증상개선을 보였으며, 합병증은 대부분의 환자에서 발생하였는데, 대개의 경우 그 증상이 미비하였고, 수일 이내에 회복되었다. 결론 : 이 논문에서는 상대적으로 짧은 추적기간과 적은 수의 환자들을 대상으로 분석을 하였으나, 고선량율 강내 방사선치료 조작은 위장관 종양의 치료에서 외부 방사선치료의 추가적 요법으로 사용할 수 있을 것으로 생각된다. Purpose : Intraluminal high dose rate brachytherapy is an accepted treatment for the tumors of GI tract. However, there is only some limited clinical data for intraluminal high dose rate brachytherapy for the tumors of GI tract. Materials and Methods : Between February 1991 and July 1993, 18 patients who have the tumors of GI tract (esophageal cancer-8 cases, rectal cancer-10 cases) were treated with high dose rate Iridium-192 afterloading system (Microselectron-HDR, Nucleron CO, Netherland) at the department of therapeutic radiology, St. Mary's hospital. Catholic university medical college. Age rage was 47-87 years with a mean age 71 years. All patients were treated with intraluminal high dose rate brachytherapy within two weeks after conventional external radiation therapy and received 3-5 Gy/fraction 3-4 times per week to a total dose 12-20 Gy (mean 17 Gy), Standard fractionation and conventional dose were delivered for external radiation therapy. Total dose of external radiation therapy ranged 41.4-59.4 Gy(mean 49.6Gy). Median follow up was 19 months. Results : The analysis was based on 18 patients. The complete response and partial response in esophageal cancer wassimilar (38%). Two year rates for survival and median survival were 13% and 10 months, respectively. Among 10 patients of rectal cancers, partial response was obtained in 6 patients (60%). There was no complete response in the patients with rectal cancer, but good palliative results were achieved in all patients. Conclusion : Although the number of patients was not large and the follow-up period was relatively short, these findings suggested that intraluminal high dose rate brachytherapy could be useful in the treatment of the patients with advanced tumors of GI tract.

신경병증성통증 모델쥐에서 냉자극 유발 통증의 교감신경성 의존도

최병욱(Byung Ock Choi),최윤(Yoon Choi),곽영섭(Young Seob Gwak),남택상(Taick Sang Nam),백광세(Kwang Se Paik),임증우(Joong Woo Leem) 대한통증학회 2000 The Korean Journal of Pain Vol.13 No.2

N/A Background: Peripheral nerve injury sometimes leads to chronic neuropathic pain such as causalgia. A subset of patients with causalgia have a sympathetically maintained pain which is often evoked by cooling stimuli. However, our knowledge on adrenergic receptor types responsible for cold-evoked pain that is sympathetically dependent is lacking. The present study was conducted to investigate subtypes of adrenoceptors involved in mediating cold-evoked pain that developed following peripheral #nerve injury. Methods: Neuropathic surgery was performed by a unilateral ligation of LS and L6 spinal nerves of rats. Behavioral sign of cold-evoked pain was examined for 5 min by measuring cumulative duration of time that the rat lifted its foot off a metal plate held at cold temperature (5℃). Whether cold-evoked pain behavior was affected by antagonists of various subtypes of adrenoceptors, which were administered intraperitoneally before and after the ligation, was investigated. Results: After ligation, duration of foot lifting on the ligated side at cold temperature increased as compared to the pre-operative period. This increase maintained for the entire 40-day test period. Pretreatment with alpha-antagonist phentolamine produced a suppression of cold-evoked pain behavior that was not affected by beta-antagonist propranolol pretreatment. Prazosin, alpha-1 antagonist, suppressed cold-evoked pain behavior when treated either before or after nerve ligation. On the other hand, alpha-2 antagonist yohimbine was without effect on cold-evoked pain behavior whether it was treated before or after the ligation. Conclusions: The results suggest that peripheral nerve injury develops cold-evoked pain that is sympathetically dependent, and that alpha-1 adrenoreceptor plays a critical role for the generation of this type of pain in its initiation as well as maintenance.

양성 뇌종양에 대한 분할 정위 방사선치료의 예비 결과

최병옥(Byung Ock Choi),강기문(Ki Mun Kang) 대한방사선종양학회 2003 Radiation Oncology Journal Vol.21 No.1

목적 : 양성 뇌종양에 대하여 분할 정위 방사선치료를 시행한 후의 임상 경과 및 방사선 반응 등을 추적하여 그 효과를 평가하고자 하였다. 대상 및 방법 : 1996년 3월부터 2002년 3월까지 양성 뇌종양으로 진단 받고 분할 정위 방사선치료를 받았던 36례를 대상으로 분석을 하였다. 대상 환자의 종양은 뇌하수체 선종 12례, 두개인두종 5례, 수막종 10례, 청신경초종 9례이었다. 방사선치료는 종양의 위치, 종류, 크기에 따라 5~10회 분할 치료로 85~90%의 등선량 곡선에 25~35 Gy까지 조사하였다. 임상 추적관찰 기간은 2~74개월(중앙값 31개월)이었고, 방사선 추적 관찰 기간은 4~56개월(중앙값 21개월)이었다. 결과 : 임상 증상이 있었던 35례 중 분할 정위 방사선치료 후 임상 증상의 호전은 13례(37.1%)에서 보였으며, 16례(45.7%)에서 증상의 변화가 없었고 증상의 악화는 6례(17.2%)에서 관찰되었다. 뇌신경장애를 동반한 28례 중 7례(25%)에서 증상 개선을 보였다. 추적 방사선 검사를 시행한 33례 중 17례(51.5%)에서 종양 크기의 감소를 보였으며, 그 중 7례(21.2%, 뇌하수체 선종-2, 두개인두종-3, 수막종-1, 청신경초종-1)는 종양의 완전 소실을 보였다. 13례(39.4%)에서 종양 크기의 변화가 없었고, 3례(9.1%)는 종양 크기의 진행을 나타내었다. 급성 부작용은 11례(30.6%)에서 관찰되었다. 결론 : 양성 뇌종양의 분할 정위 방사선치료는 심각한 부작용 없이 시행할 수 있는 안전하고 효과적인 치료법이었다. 그러나, 정확한 역할에 대해서는 좀 더 많은 환자와 장기간의 추적관찰이 필요할 것으로 사료되었다. Purpose : To evaluate the role of fractionated stereotactic radiotherapy (FSRT) in the management of benign brain tumors, we reviewed the clinical, and radiographic responses of patients treated. Methods and Materials : Between March 1996 and March 2002, 36 patients with benign brain tumors were treated by FSRT. The pathological diagnoses consisted of pituitary adenomas (12 patients), craniopharyngiomas (5 patients), meningiomas (10 patients), and acoustic neurinomas (9 patients). Radiotherapy doses of 25 to 35 Gy (3~6 Gy/fraction, 5~10 fractions) were prescribed to the 85~90% isodose line, depending upon the location, size and volume of the tumors. The median clinical and radiographical followup periods were 31 (range, 2~74) and 21 (range, 4~56) months, respectively. Results : In the 35 patients that could be evaluated for their clinical response, 13 (37.1%) were considered improved, 16 (45.7%) stable and 6 (17.2%) worse. Of the 33 patients who had radiographic studies, tumor shrinkage was noted in 17 (51.5%), tumor stabilization in 13 (39.4%), and tumor progression in 3 (9.1%). Of the 17 tumor shrinkage patients, 7 (21.2%) showed a complete response. Acute radiation-induced complications occurred in 11 (30.6%) patients. Conclusion : FSRT is considered a safe and effective treatment method for benign brain tumors, but large numbers of patients, with relatively long follow-up periods are needed to assess the exact role or effect of FSRT.

부산 , 경남지역 주강 공장의 CO2 주형 고사의 발생실태와 재생에 관한 연구

최준오(Jun Oh Choi),김민섭(Min Seop Kim),최인석(In Seok Choi),천병욱(Byung Wook Cheon),최창옥(Chang Ock Choi) 한국주조공학회 2002 한국주조공학회지 Vol.22 No.3

N/A According to the investigation of waste CO_2 molding sand in the 15 steel foundries in Busan and Gyeong area, about 1 ton of waste CO_2 molding sand per ton of steel castings production was produced In order to reduce amount of Na_2O, Loss of Boiling (L.O.B), Loss of Ignition (L.O.I), Conductivity and PH which are present in the waste CO_2 molding sand below the reclamation effect, more than 50% of elimination for reclamation was required. It was found that the waste CO_2 molding sand does not contain a harmful component designated by industrial waste materials. Reclamation of the waste CO_2 molding sand was practically achieved by an abrasive-dry reclamation process. According to bench time of the sodium silicate-bonded CO_2 molding sand, reduction of compressive strength and surface stability index(S.S.I) become slowdown. Therefore, the reclaimed sand could be allowed the reuse of molding sand in CO_2 molding process including core sand.

Synthesis of Mannich Bases of Antineoplaston A10 and their Antitumor Activity

Choi, Bo-Gil,Seo, Hee-Kyoung,Chung, Byung-Ho,Choi, Sang-Un,Lee, Chong-Ock The Pharmaceutical Society of Korea 1994 Archives of Pharmacal Research Vol.17 No.6

Some Mannich bases of Antineoplaston A10 which is antitumor agent under chlinical investigation were synthesized and tested fro cytotoxicity. The tested compounds (2a, 2b, 2d) showed good activity comparable to that of carboplatin.

Reduction of ischemia-induced cerebral injury by all-trans-retinoic acid

Choi, Byung-Kwan,Kim, Ji-Hoon,Jung, Jong-Soo,Lee, Young-Suk,Han, Myoung-Eun,Baek, Sun-Yong,Kim, Bong-Seon,Kim, Jae-Bong,Oh, Sae-Ock Springer-Verlag 2009 Experimental brain research Vol.193 No.4

<P>Ischemia-induced cerebral injury evolves over a longer period than previously believed through post-ischemic inflammation. Retinoic acid (RA) has been shown to exert cytoprotective effects on several cells, but its effects on ischemia-induced cerebral injury have been poorly characterized. The aim of the present study was to examine the effects of all-trans-RA on ischemia-induced cerebral injury and elucidate the underlying mechanism. All-trans-RA treatment reduced the size of the ischemia-induced cerebral infarct. To elucidate the underlying mechanism, ischemia-induced cerebral inflammation was studied by examination of expressions of interleukin 1 beta (IL-1 beta) and ED-1. RA treatment significantly reduced the cerebral inflammation. Moreover, cerebral ischemic induction of cyclooxygenase-2 (COX-2) and CCAAT/enhancer binding protein beta (C/EBP beta), which binds to the COX-2 promoter, was also inhibited by RA. These results suggest that RA can reduce ischemia-induced cerebral injury by an anti-inflammatory action, which may be effected via inhibition of C/EBP beta-mediated COX-2 induction.</P>