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      • 國民學校 敎師 自然 및 算數科 再敎育의 分析的 硏究 : Based on the Choong Buk Province

        黃秉德,梁仁煥,崔炳文,趙璇衡,朴根生 淸州大學校 科學敎育硏究所 1977 淸州大學校 科學敎育硏究所 Vol.1 No.-

        Our college has retrained many primary school teachers during 5 years is science, and during 4 years in case of mathematics. Many problems are found out in the process of retraining them in our school. This study is aimed to research the actual condition of the retraining and to find out the way to improvement from the problems. However, Our study will have some limitation as follows: (1) For our study, only 300 teachers are chosen from the total 1,869 attended at our college(Cheong Ju Teachers College) in 1976. (2) The administrational and financial affairs are analyzed only according to the Ministry of Education with UNICEF funds from 1972 to 1976, and (3) We didn't take any consideration of Ministry of Education Project in Suggesting the way of improvement. Following are some problems found in our study: 1) Throughout the nation, only 23% of primary school teachers were taught in science and mathematice reservice work during the 5 years, and it can be said that it takes about 20 years to retrained all the teachers without consideration of natural increase of teachers. 2) The proportion of selecting primary school teachers in all the country for this reservice training is extreme, for example, Jeju Province is 57.9%, Seoul 17.7%. 3) The proportion of woman teachers selected in Choong Buk primary school is only 3.5% of total woman teachers, who takes 32% of total Choong Buk primary teachers during 5 years. Therefore, it is said that the number is very little. 4) Some teachers have been reselected in the reservice training. In case of the Choong Buk Board of Education. the 6% of teachers selected once were reselected for 5 years. 5) When the test are enforced on attendants to get data before the reservice training. We could find that they didn't understand the basic concept of science except a grade under their charge. 6) In the process of inquiry study, they didn't know even the scientific terms of expectation and reasoning. 7) After 60 hours of reservice training course. We tested them about understanding of the contents of text, and their marks are from 10 to 100. the marks show large individual difference among them. 8) Some teachers may have neither teaching ability nor knowledge of the basic concept, that is 11.3% of total attendants are less than 30 marks in mathematics test. 9) It is too very large work to study reservice text during the 60 hours. 10) There are many difficult signs in the mathematics reservice text having no connection with the actual primary school mathematics text book. 11) In the reservice text of science, there are omitted the method of teaching materials production, the model of inquiry learning, and the evaluation method. 12) From the analysis of questionary response for finding the actual condition of administration of teaching materials, We could find out 15% of primary schools in Choong Buk Province do almost not prepare teaching materials, and 15% of its never put them to practical use. Therefore, We could say that total 30% of them have been teaching without teaching materials. 13) The 42% of attendants in mathematics class answer that they do not understand the new mathematical signs, and 42% of them answer the shortage of hours (60 hours) to understand their reservice text book. 14) The 25% of them answer that they teach children with cramming education, and almost of them want good teachers guide books. As mentioned above, there are found many problems to be solved for reservice training of science education in our country. Some of them will be solved in our study. So We find out its and We suggest the ways solving the problems as follows: A. On the administration of reservice training. 1) The reservice training work for primary school teachers is very significant and will have to be continued. 2) It will be done in not only summer vacation but also winter one for finishing immediatly all over the country. 3) The 60 hours of science reservice training course work are very short, and the classmember of attendants will be regulated. 4) The funds for reservice operation and travelling expenses for attendants will be realized. B. On selecting the attendants 1) When the attendants are selected, there will be consideration of age, rank, term of their service, sex and academic background. 2) as far as possible, it will be selected as homogeous groups, and it will be effective to teach them with division between class teacher and nonclass teacher. 3) When select attendants are it will be taken consideration of balance between city and province for the diffusion effect and parallel development in reservice training work. 4) It must give a chance to woman as same as to man teacher according to a rule of equal select chance. 5) The principal, instructor and school inspector will be reeducated for fixing of science curriculum. C. On reservice training text book 1) The text book must reedit moderatly for 60 hours, or the time of retraining for the text book finished will be extented. In our opinion, it is to be desired that the time have to be added. 2) The difficult signs must be omitted, taking into account for the mathematics knowledge and time of education period. 3) In the science reservice training text book, it must supplement the tack for framming of inquiry teaching plan, the method for making teaching materials, and the skill for replacing of teaching materials. D. For the curriculum management of science. 1) The Governmental Company must settle the shortage of science teaching materials in primary school. 2) For the charge of the old state of teaching method, the teachers must devote themselves to teach children without miscellaneous duties. 3) The authorities concerned (for example, Ministry of Education, Teachers College, etc.) must make guide books for science teachers, and supply them to primary school teachers. 4) It must be given the chance of long period reeducation to the incompetent primary school teachers, and problem will have to be studied under the situation of educational administration.

      • KCI등재후보

        백서에서 Depulpin®과 Formocresol에 대한 치수와 치근단 조직의 반응

        문형인,김선호,황윤찬,오병주,황인남,김선헌,정선와,윤창,오원만 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

        One fifth dilution of formocresol is usually for pulpotomy of the primary teeth and emergency pulpotomy of the permanent teeth. However, the use of formaldehyde has been subjected to criticism because it may be absorbed into the blood stream and become distributed systemically, it may also alter the pulp tissue rendering it immumologically active, and have carcinogenic potential. Recently Depulpin®(VoCo., Germany) gains popularity as a devitalizing agent during root canal therapy in spite of high concentration of 49% paraformaldehyde because it facilitate devitalization of pulp and make root canal therapy easier. But there have been not enough publications about the reaction of pulp and periapical tissue caused by Depulpin. This study was performed to evaluate the histological changes in pulp and periapical tissue of rats after pulpotomy using formocresol and Depulpin and to elucidate the toxic effects of these agents. Thirty six Sprague-Dawley rats were anesthetized by intraperitoneal injection of ketamine. Maxillary first molar teeth were used for pulpotomy with formocresol and Depulpin. Rats were sacrificed after 2 days, 4 days, 1 week, 2 weeks, 3 weeks and 4 weeks respectively. Specimens were histologically observed by light microscope changes in pulp and periapical tissue. The obtained results were as follows. 1. Formocresol group A zone of fixed tissue, in which odontoblasts could clearly be defined, was present directly underneath the pulpotomy dressing in almost all teeth of this group. This was followed by an area of necrotic tissue which resembled dried out fibrous tissue with no cellular detail except some pyknotic nuclei. In the specimens of after 2 days, 4 days, 1 week, 2 weeks in which vital tissue was present. it was separated from the fibrous area by a zone of inflammation. In the specimens of after 3 weeks and after 4 weeks, inflammatory infiltrate was in the periodontal ligament adjacent to the apical foramina of the teeth. 2. Depulpin® group The area of necrotic tissue which had no cells and fibers , was present adjacent to the dressing. This was followed by dried out fibrous tissue with no cellular details except some pyknotic nucleli. A short stump of vital pulp with odontoblasts was present at the end of the canal after 2 days. Inflammatory infiltrate was in the periodontal ligament after 4 days and after 1week. Severe root resorption and necrosis of periapical tissue opposite the root resorption site were defined after 2 weeks and after 3 weeks. Periapical lesion which consist of necrotic tissue surrounded by a fibrous connective wall. was found after 4 weeks. The results indicated that Depulpin can cause more adverse reaction to the dental pulp and periapical tissue than formocresol, and further studies are needed for its clinical use with safety.

      • KCI등재후보

        Factors of Cardiopulmonary Resuscitation Outcome for In-hospital Adult Patients

        In Byung Kim,Sang Won Chung,Dong Seok Moon,Ki Hyun Byun Korean Society of Critical Care Medicine 2007 Acute and Critical Care Vol.22 No.2

        BACKGROUND: The purpose of this study was to evaluate the factors of cardiopulmonary resuscitation (CPR) outcome for in-hospital adult patients, acquiring data with standardized reporting guideline of in-hospital cardiopulmonary resuscitation in Korea. METHODS: All adult cardiac arrest patients from July 2004 to December 2006 in this general hospital were included. Their clinical spectrums were reviewed retrospectively using Utstein-style based template. RESULTS: For the study time period, one hundred and forty-two patients underwent cardiac arrest in this hospital. 136 patients were performed CPR. Return of spontaneous circulation (ROSC) occurred in 42 cases, and 15 patients were survived to hospital discharge. A shorter CPR time and a lower Simplified Acute Physiology Score II (SAPS II) were significant for survivor to hospital discharge (p

      • SCOPUSKCI등재

        단계적 온도 하강법을 이용한 췌도세포 냉동보존법

        정인경,오승훈,김병준,양태영,이병완,하창영,노정현,정재훈,민용기,이명식,이문규,김광원 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.26 No.1

        연구배경:최근 당뇨병의 새로운 치료법으로 시도되고 있는 췌도이식은 충분한 췌도수의 확보와 췌도생존율을 높이기 위한 면역억제제 사용이 제한점이 되고 있다. 본 연구의 목적은 이식 전 충분한 췌도 수의 확보를 위해 분리한 췌도를 냉동보존하는 방법을 확립하고 냉동보존한 백서 췌도세포의 시험관내 그리고 생체내 기능을 조사하였다. 방법:분리한 백서의 췌장소도를 48시간 배양한 후 한 시험관당 췌도세포 1000개씩 나누었다. 냉동보존은 6개의 시험관에 DMSO를 첨가한 후 초 냉각(supercooling), 핵화(nucleation)단계를 거친 후 99% isopropanol과 액체질소가 들어있는 dewer를 이용하여-0.25℃/분의 냉각속도로 -40℃까지 단계적으로 얼린후-70℃ 액체질소 탱크에 보관했다. 해동은 냉동시킨 vial들을 액체 질소 태으에서 꺼내 37℃ 항온조에 담가 급격히 해동시킨 후, 원심분리하여 상층액을 제거하고 각 vial에 0.75M sucrose 용액을 가한 후, 10% fetal calf serum이 함유된 RPMI 1640 media에서 배양하였다 각각 6개의 시험관에서 해동한 췌도들을 광학현미경 및 형광현미경하에서 췌도의 모양과 생존율에 대해 조사하고 인슐린 정적반응을 알아보았다. 또한 분리한 췌도를 냉동보존하지 않고 이식한 경우를 대조군(6마리)과 생체내 기능을 비교하였다. 결과:① 냉동보존후 획득한 췌도의 수와 생존율 해동후 획득한 췌도의 수는 해동시킨 당일날이 902±21, 24시간 배양 후에는 857±16, 72시간 후에는 817±18개로 점차 감소되었다. AO/PI 염색상 각 췌도의 생존율은 냉동 전을 100으로 하였을 때 해동당일, 24시간 후, 72시간 후가 각각 60±5, 80±5, 90±5%로 해동후 3일간 배양하였을 때 냉동전의 수준으로 회복하였다. ② 냉동보존후 췌도의 포도당에 대한 정적 인슐린 분비능:냉동직후 감소된 경향을 보였으나 해동후 3일간 배양한 췌도의 인슐린 분비는 냉동전과 통계적으로 의미있는 차이가 없이 냉동보존 전의 수준으로 회복되었다. ③ 냉동보존후 췌도의 포도당에 대한 동적 인슐린 분비능:냉동보존한 췌도를 해동후 3일째의 인슐린 동적 분비능은 냉동 전과 마찬가지로 자극 인슐린의 반응의 제1기와 2기가 잘 관찰되었다. ④ 냉동보존한 췌도세포 이식 후 혈당 변화:스트렙토조토신으로 유도된 당뇨병 쥐에 췌도이식 후 혈당은 냉동보존한 췌도이식군에서 대조군에 비해 혈당의 조절효과가 더 오래 지속되었다. 결론:소동물에서 단계적 온도 하강법을 이용한 췌도세포 냉동보존법을 확립하였으며 이는 기능, 구조 및 생존율에 큰 이상을 보이지 않았으므로 장차 사람의 췌도세포 동종이식시 부족한 췌도세포수를 극복하고 면역반응을 줄일 수 있는 매우 유용한 방법이 될 것으로 판단된다. Background : Although islet transplantation has been attempted to reverse the state of diabetes, achieving a critical number of islets and modulating the immune response limit the success of islet transplantation. Cryo-preservation of islets offers many important benefits for islet transplantation by collecting islets with a wide variety of HLA phenotypes and islet MHC expression. The aims of this study was to determine the optimal conditions for cryo-preservation by using a controlled cooling method and to evaluate in vitro and in vivo functional properties of the cryo-preserved islets. Methods : Collagenase-isolated, Ficoll-purified islets were cultured for 48 hours. They were aliquoted into freezing tubes (1000 islets per tube), equilibrated with 2M dimethyl sulfoxide (DMSO) in three steps, supercooled, nucleated, and controll-cooled at rate of 0.25℃/min to - 40℃ prior to storage at - 196℃. Rapid thawing and removal of DMSO with 0.75 M sucrose preceded 48 hour of culture and the morphology, viability, glucose-induced insulin secretion, and in vivo function of rats transplanted with cryopreserved islets was reexamined. Results : ① Recovery was 90.2±0.2%, 85.7±0.1% and 81.7±0.1% immendiately after, 24 hours and 72 hours after thawing respectively. The viability was 60±5%, 80±5%, 90±5% immediately after, 24 hours and 72 hours after thawing respectively. ② The glucose-stimulated-insulin secretion (GSIS) tended to decrease immediately after thawing, but GSIS increase to the level of pre-cryopreservation 72 hours after thawing. ③ The in dynamic GSIS, the first and the second phase of insulin secretion were well preserved in islets cultured for 72 hours after thawing. ④ The cryopreserved islets were cultured for 3 days and transplanted into renal sub-capsular space of streptozotocin (STZ) induced diabetic rats. The duration of normoglycemia in the STZ-induced diabetic rats transplanted with cryopreserved islets was significantly longer than of the fresh islets. Conclusion : The optimal condition of cryopreservation using the controlled cooling method was established in rat pancreatic islets. This cryopreservation method can be a feasible approach for human islet transplantation (J Kor Diabetes Asso 26:64~74, 2002).

      • SCIESCOPUSKCI등재
      • KCI등재

        Developing Core Elements and Checklist Items for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals: A Modified Delphi Survey

        Cheong Hae Suk,Park Kyung-Hwa,Kim Bongyoung,Eun Byung Wook,Kim Hyung-Sook,Kim Yong Chan,Lee Hyukmin,Jeong Su Jin,Moon Chisook,Kim Shin-Woo,Yoon Young Kyung,Hwang In Sun,Park Choon-Seon,Lee Mi Suk,Kim 대한감염학회 2023 Infection and Chemotherapy Vol.55 No.1

        Background: Antimicrobial stewardship programs (ASPs) aim to optimize antimicrobial use by minimizing the spread of antimicrobial resistance. The core elements for implementing ASPs in healthcare facilities have been developed by the World Health Organization, international research group and government agencies of various countries. However, to date, there is no documented core elements for implementation of ASP in Korea. This survey aimed to establish a national consensus on a set of core elements and their related checklist items for the implementation of ASPs in Korean general hospitals. Materials and Methods: The survey was conducted from July 2022 to August 2022 by the Korean Society for Antimicrobial Therapy with support from the Korea Disease Control and Prevention Agency. A literature review was conducted by searching Medline and relevant websites to retrieve a list of core elements and checklist items. These core elements and checklist items were evaluated by a multidisciplinary panel of experts using a structured modified Delphi consensus procedure, using two-step survey included online in-depth questionnaires and in-person meeting. Results: The literature review identified 6 core elements (Leadership commitment, Operating system, Action, Tracking, Reporting, and Education) and 37 related checklist items. Fifteen experts participated in the consensus procedures. Ultimately, all 6 core elements were retained, and 28 checklist items were proposed, all with ≥80% agreement; in addition 9 items were merged into 2 items, 2 items were deleted, and 15 items were rephrased. Conclusion: This Delphi survey provides useful indicators for the implementation of ASP in Korea and suggests national policy improvement about the barriers (e.g., shortage of staffing and financial support) existing in Korea for optimal implementation of ASPs.

      • SCIESCOPUSKCI등재
      • 가요성 알루미늄피 케이블 (MCIF CABLE)을 적용한 일체형 배선시스템

        구경완(KOO Kyung Wan),전인석(CHUN In Suk),문영재(MOON Young Jae),이병용(Lee Byung Yong) 대한전기학회 2007 대한전기학회 학술대회 논문집 Vol.2007 No.4

        This paper introduces the IN-FLEX system using aluminum clad flex cable, which is expected to alternate the conventional wiring method, such as, a steel pipe wiring method, and a synthetic resin pipe wiring method. The aluminum clad flex cable has a superior operation characteristics in heat dissipation property, in installation and maintenance facility, flammability, and appearance. Moreover, the IN-FLEX system adopted an easy connection mechanism which enable to reduce the time, hands and expense for the installation and maintenance of the system. Certification tests verifying the superior operation characteristics and reliability of the system using aluminum clad flex cable were carried with standard method in KOLAS certification institute.

      • 유방암의 항암치료

        이안복,문병인 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2

        Breast cancer is the second most common cancer in Korean women and its incidence has increased. Among the various treatment methods for breast cancer, chemotherapy plays an important role. The use chemotherapy to treat breast cancer began at the mid 20th century and first combination chemotherapy was conducted in mid 1970s. This chemotherapy reduced breast cancer mortality up to 25~30%, anthracycline and taxane based chemotherapeutic regimens are widely used. Chemotherapy could be classified to neoadjuavnt, adjuvant and palliative setting according to its aim and role. In this review, various drug therapeutic options and their backgrounds are considered based on neoadjuvant, adjuvant and metastatic systemic therapies

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