Effects of ultraviolet-C treatment in Teflon®-coil on microbial populations and physico-chemical characteristics of watermelon juice

Feng, M.,Ghafoor, K.,Seo, B.,Yang, K.,Park, J. Elsevier Science 2013 Innovative food science & emerging technologies Vol.19 No.-

The efficacy of UVC radiation for inactivation of bacteria (aerobic, coliform) and yeast/mold in watermelon juice using helix Teflon®-coil was investigated. Changes in microbial load, pH, <SUP>o</SUP>brix, color (L*, a*, and b*), lycopene, and phenolics in juice, after UVC treatment were evaluated for 37days of storage at 5+/-1<SUP>o</SUP>C. Microbial inactivation was dependent on the UVC intensity between 2.7 and 37.5J/mL. UVC treatment inactivated all (2.6logCFU/mL) coliform bacteria. UVC (37.5J/mL) reduced total aerobes and yeast/mold by 1.47 and 0.99logCFU/mL, respectively. The microbial load in treated juice remained lower than 6.0logCFU/mL until the 31st day of storage. UVC treatment resulted in no-significant effects on pH, <SUP>o</SUP>brix, color change, lycopene, and phenolics, the values of which remained consistent with those of a control until 25th day of storage. UVC treated juice had lower b* (yellowness) and higher a* (redness) colors than untreated juice. Industrial relevance: Watermelon juice is a potential health food and strategies to increase its shelf-life with minimal or no damage to nutritional components are crucial for obtaining more commercial benefits. Our study suggests that a Teflon®-coil UVC system can be effectively used as a non-thermal method for microbial inactivation in watermelon juice and to improve the product shelf-life with no significant effects on different physico-chemical and nutritional characteristics.

Finite-element analysis and design of aluminum alloy RHSs and SHSs with through-openings in bending

Ran Feng,Tao Yang,Zhenming Chen,Krishanu Roy,Boshan Chen,James B. P. Lim 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.46 No.3

This paper presents a finite-element analysis (FEA) of aluminum alloy rectangular hollow sections (RHSs) and square hollow sections (SHSs) with circular through-openings under three-point and four-point bending. First, a finite-element model (FEM) was developed and validated against the corresponding test results available in the literature. Next, using the validated FE models, a parametric study comprising 180 FE models was conducted. The cross-section width-to-thickness ratio (b/t) ranged from 2 to 5, the hole size ratio (d/h) ranged from 0.2 to 0.8 and the quantity of holes (n) ranged from 2 to 6, respectively. Third, results obtained from laboratory test and FEA were compared with current design strengths calculated in accordance with the North American Specifications (NAS), the modified direct strength method (DSM) and the modified Continuous strength method (CSM). The comparison shows that the modified CSM are conservative by 15% on average for aluminum alloy RHSs and SHSs with circular through-openings subject to bending. Finally, a new design equation is proposed based on the modified CSM after being validated with results obtained from laboratory test and FEA. The proposed design equation can provide accurate predictions of flexural capacities for aluminum alloy RHSs and SHSs with circular throughopenings.

Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets

Norberg, Erik,Lako, Ana,Chen, Pei-Hsuan,Stanley, Illana A,Zhou, Feng,Ficarro, Scott B,Chapuy, Bjoern,Chen, Linfeng,Rodig, Scott,Shin, Donghyuk,Choi, Dong Wook,Lee, Sangho,Shipp, Margaret A,Marto, Jarr Macmillan Publishers Limited, part of Springer Nat 2017 CELL DEATH AND DIFFERENTIATION Vol.24 No.2

<P>Diffuse large B-cell lymphomas (DLBCLs) are a highly heterogeneous group of tumors in which subsets share molecular features revealed by gene expression profiles and metabolic fingerprints. While B-cell receptor (BCR)-dependent DLBCLs are glycolytic, OxPhos-DLBCLs rely on mitochondrial energy transduction and nutrient utilization pathways that provide pro-survival benefits independent of BCR signaling. Integral to these metabolic distinctions is elevated mitochondrial electron transport chain (ETC) activity in OxPhos-DLBCLs compared with BCR-DLBCLs, which is linked to greater protein abundance of ETC components. To gain insights into molecular determinants of the selective increase in ETC activity and dependence on mitochondrial energy metabolism in OxPhos-DLBCLs, we examined the mitochondrial translation pathway in charge of the synthesis of mitochondrial DNA encoded ETC subunits. Quantitative mass spectrometry identified increased expression of mitochondrial translation factors in OxPhos-DLBCL as compared with the BCR subtype. Biochemical and functional assays indicate that the mitochondrial translation pathway is required for increased ETC activity and mitochondrial energy reserves in OxPhos-DLBCL. Importantly, molecular depletion of several mitochondrial translation proteins using RNA interference or pharmacological perturbation of the mitochondrial translation pathway with the FDA-approved inhibitor tigecycline (Tigecyl) is selectively toxic to OxPhos-DLBCL cell lines and primary tumors. These findings provide additional molecular insights into the metabolic characteristics of OxPhos-DLBCLs, and mark the mitochondrial translation pathway as a potential therapeutic target in these tumors.</P>

재래 흑돼지와 중국 재래돈간의 Melanocortin Receptor 1(MC1R) 유전자의 유전자형 분석

이성수,양보석,정진관,고서봉,오성종,양영훈,김규일,이찬동,풍서당 한국동물자원과학회 2001 한국축산학회지 Vol.43 No.1

PCR-RFLP analysis of Melanocortin receptor 1 (MC1R) gene was carried out to investigate the genotype distribution in Korean-Native and Chinese-Native pig breeds(Neijiang, Putian, Wannanhua and Jinhua). Allelic variants of MC1R in pigs were analyzed by digestion of BspH I , AccII and Hha I . Ncijiang. Wannanhua and Jinhua had only MC1R*2 allele which is considered to be typical genotype for Meishan and Large Black. Among 20 Korean-Native Pigs and 5 Putian pigs, 10 and 2 heads had the MC1R*3 allele (*2/3 or 3/3), respectively, which was detected in European pig breeds such as Hampshire, Large White, and Pietrain. The remaining animals possessed the genotype MC1R*2/2, probably reflecting the genetic introgression of MC1R*3 allele into Korean-Native and Putian pig breeds by the crossbreeding for improvement. The alleles MC1R*l and MC1R*4, which are considered to be typical allele for European Wild Boar with wild-type coat color and Duroc with red coat color, respectively, were not detected in pig breeds used in this experiment. These results indicate that the analysis of genotype frequencies of MC1R gene may be a useful tool for the conservation of Korean-Native and Chinese-Native pig breeds.

Improvement of lower hybrid current drive systems for high-power and long-pulse operation on EAST

Wang M.,Liu L.,Zhao L.M.,Li M.H.,Ma W.D.,Hu H.C.,Wu Z.G.,Feng J.Q.,Yang Y.,Zhu L.,Chen M.,Zhou T.A.,Jia H.,Zhang J.,Cao L.,Zhang L.,Liang R.R.,Ding B.J.,Zhang X.J.,Shan J.F.,Liu F.K.,Ekedahl A.,Gonich 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.11

Aiming at high-power and long-pulse operation up to 1000 s, some improvements have been made for both 2.45 GHz and 4.6 GHz lower hybrid (LH) systems during the recent 5 years. At first, the guard limiters of the LH antennas with graphite tiles were upgraded to tungsten, the most promising material for plasma facing components in nuclear fusion devices. These new guard limiters can operate at a peak power density of 12.9 MW/m2 . Strong hot spots were usually observed on the old graphite limiters when 4.6 GHz system operated with power >2.0 MW [B. N. Wan et al., Nucl. Fusion 57 (2017) 102019], leading to a reduction of the maximum power capability. With the new limiters, 4.6 GHz LH system, the main current drive (CD) and electron heating tool for EAST, can be operated with power >2.5 MW routinely. Long-pulse operation up to 100 s with 4.6 GHz LH power of 2.4 MW was achieved in 2021 and the maximal temperature on the guard limiters measured by an infrared (IR) camera was about 540 C, much below the permissible value of tungsten material (~1200 C). A discharge with a duration of 1056 s was achieved and the 4.6 GHz LH energy injected into the plasma was up to 1.05 GJ. Secondly, the fully-activemultijunction (FAM) launcher of 2.45 GHz system was upgraded to a passive-active-multijunction (PAM), for which the density of optimum coupling was relatively low (below the cut-off value). Good coupling with reflection coefficient ~3% has been achieved with plasma-antenna distance up to 11 cm for the new PAM. Finally, in order to eliminate the effect of ion cyclotron range of frequencies (ICRF) wave on 4.6 GHz LH wave coupling, the location of the ICRF launcher was changed to a port that is located 157.5 toroidally from the 4.6 GHz LH system and is not magnetically connected

In situ neutron diffraction analyses of temperature and stresses during friction stir processing of Mg-3Al-1Zn magnesium alloy

Woo, W.,Feng, Z.,Clausen, B.,David, S.A. North-Holland 2017 Materials letters Vol.196 No.-

<P><B>Abstract</B></P> <P>The evolution of temperature and thermal stresses were examined during friction stir processing of a magnesium alloy using in situ neutron diffraction. Measured total lattice strains were de-convoluted into the thermal and stress components. It shows the maximum temperature of 464°C and compressive stress distributions up to −52MPa underneath the tool via the thermo-mechanical deformation in terms of the Zener-Hollomon parameter of 4.51×10<SUP>10</SUP> s<SUP>−1</SUP>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> In situ neutron diffraction were experimented during friction stir processing of an Mg alloy. </LI> <LI> The diffraction peaks were de-convoluted into the transient temperature and thermal stresses. </LI> <LI> Analyzed inhomogeneous distributions of temperature and stresses underneath the tool. </LI> <LI> The results are applied for the grain size estimation via the Zener-Hollomon parameter. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Development of the 3.7 GHz LHCD System on HL-2A

B. Lu,M. Huang,H. Zeng,X. Y. Bai,X. H. Mao,Z. H. Lu,J. Liang,Z. H. Kang,M. W. Wang,K. Feng,H. Wang,C. Wang,J. Q. Wang,S. Wei,T. Yao,Y. N. Bu,J. Feng,G. Y. Cheng,S. D. Song,D. H. Xia,J. Rao 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.8

A 2 MW-3.7 GHz lower hybrid current drive (LHCD) system is under development for physicsexperiments on the HL-2A device. The RF Power is generated by four TH2103A klystron amplifiersand propagates in the TE10 mode through WR284 waveguides. The transmission lines with a lengthof 20 m to 30 m are pressurized with 2 bars of nitrogen to decrease the possibility of arcing. Thelauncher, based on the passive-active multi-junction (PAM) concept, has been developed and iscurrently being realized. It was designed for a power spectrum peaked at Nk = 2.75 with goodcoupling properties over a wide range of plasma parameters. The four klystrons are fed by ahigh-voltage power supply (HVPS) based on the pulse step modulation (PSM) concept with a fastswitch-off time of less than ten μs. This system is expected to be in operation within 1 years and willexplore many international thermonuclear experimental reactor (ITER) related LH experiments inthe following years.

Stabilization of a hyaluronate-associated gene delivery system using calcium ions

Feng, M.,Ibrahim, B.,Wilson, E.,Doh, K. O.,Bergman, B.,Park, C.,Yeo, Y. Royal Society of Chemistry 2014 Biomaterials Science Vol.2 No.6

Modelling the Mont Terri HE-D experiment for the Thermal–Hydraulic–Mechanical response of a bedded argillaceous formation to heating

Garitte, B.,Nguyen, T. S.,Barnichon, J. D.,Graupner, B. J.,Lee, C.,Maekawa, K.,Manepally, C.,Ofoegbu, G.,Dasgupta, B.,Fedors, R.,Pan, P. Z.,Feng, X. T.,Rutqvist, J.,Chen, F.,Birkholzer, Jens,Wang, Q. Springer 2017 Environmental Earth Sciences Vol.76 No.9

<P>Coupled thermal-hydrological-mechanical (THM) processes in the near field of deep geological repositories can influence several safety features of the engineered and geological barriers. Among those features are: the possibility of damage in the host rock, the time for re-saturation of the bentonite, and the perturbations in the hydraulic regime in both the rock and engineered seals. Within the international cooperative code-validation project DECOVALEX-2015, eight research teams developed models to simulate an in situ heater experiment, called HE-D, in Opalinus Clay at the Mont Terri Underground Research Laboratory in Switzerland. The models were developed from the theory of poroelasticity order to simulate the coupled THM processes that prevailed during the experiment and thereby to characterize the in situ THM properties of Opalinus Clay. The modelling results for the evolution of temperature, pore water pressure, and deformation at different points are consistent among the research teams and compare favourably with the experimental data in terms of trends and absolute values. The models were able to reproduce the main physical processes of the experiment. In particular, most teams simulated temperature and thermally induced pore water pressure well, including spatial variations caused by inherent anisotropy due to bedding.</P>

Numerical investigation on residual stress in photovoltaic laminates after lamination

Q. Z. Zhang,B. F. Shu,M. B. Chen,Q. B. Liang,C. Fan,Z. Q. Feng,P. J. Verlinden 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.2

A series of simulations were carried out to investigate the residual stress induced in the photovoltaic laminate during the cooling processafter lamination with a global model and several submodels. The simulations focus separately on the effects of the cooling rate, thecell layout and anisotropy on the residual stress and deformation of the photovoltaic laminate in a comparative manner with the finiteelement method. The results have shown that significant stress concentration and twist occurs in the interconnection region in the cell. Inaddition, different cooling rates, cell layouts and anisotropy only influence the largest stress rather than the stress distribution and deformation. Therefore, the results of a uniform stationary isotropic model with fewer cells can provide enough insight into the stress distributionin real photovoltaic laminates and the modified largest first principal stress can be used for design and verification.