소장내용물의 위내역류 및 위내용물 배출시간에 관한 연구

김진호,박승철,이형호,안일민,박영태,김열흥,이창흥 대한내과학회 1986 대한내과학회지 Vol.30 No.2

Radionuclide enterogastric scintigraphy was done with (99m)Tc-DISIDA and (111)In-DTPA in 35cases; control group 5, gastric ulcer group 6, subtotal gastrectomy with Billroth g group 5, and functional gastrointestinal disorder group with or without grossly mixed bile in the gastric juice 19 cases. The results were: 1) Enterogastric reflux was very significantly increased in the subtotal gastrectomy with Billroth II group (p$lt;0, 001), 2) Gastric emptying was significantly delayed in the functional gastrointestinal disorder groups with or without grossly mixed bile (p$lt;0.05, p$lt;0. 001). 3) Enterogastric reflux was not significantly increased in the gastric ulcer group. 4) Enterogastric reflux was not significantly different between the functional gastrointestinal groups with or without grossly mixed bile in the gastric juice. 5) Inverse correlation between the gastric emptying indices and the enterogastric reflux indices was not proved (r=-0.37).

방전 플라스마에 의한 CFC-12(CCl2F2)의 분해

황명환,우인성,조정국,강현춘,안형환,이한섭,강안수 한국산업안전학회 1999 한국안전학회지 Vol.14 No.3

Decomposition efficiency, power consumption, and applied voltage of CFC(Chlorofluorocarbon) were investigated by SPCY(surface induced discharge plasma chemical processing) reactor to obtain optimum process variables and maximum decomposition efficiencies. Decomposition efficiency of CFC-12 with various electric frequencies(5∼50㎑). flow rates (100∼1,000mL/min), initial concentrations(100∼1,000ppm), electrode materials(W, Cu. Al), electrode thickness(1, 2, 3mm) and reference gases(N₂, O₂, air) were measured and the products were analyzed with FT-IR. Experimental results showed that at the frequency of 10kHz, the highest decomposition efficiency of 92.7% for CFC-12 were observed at the power consumptions of 29.6W, respectively, and that decomposition efficiency decreased with increasing frequency above 20㎑ and decomposition efficiency per unit power were 3.13%/W for CFC-12. Decomposition efficiency was increased with increasing residence times and with decreasing initial concentration of pollutants. Decomposition efficiency was increased with increasing thickness of discharge electrode and the highest decomposition efficiency was obtained for the electrode diameter of 3mm. As the electrode material, decomposition efficiency was in order that tungsten(W), copper(Cu), aluminum (Al).

Castleman 씨 병에 동반된 신유전분증

김연수,한진석,이정상,김병국,이중건,정윤철,이진학,최영진,안규리,김성권,이현순 대한내과학회 1994 대한내과학회지 Vol.46 No.2

Castlemam's disease is an asymptomatic and benign lymph node hyperplasia which is frequently manifested as mediastinal mass in over 70% of cases. Amyloidosis is rarely associated with Castleman's disease. Recently we experienced a patient with nephrotic syndrome due to renal amyloidosis who had been previously diagnosed as Castleman's disease of retroperitoneal lymph node enlargement. A 47-year old woman was admitted because of generalized edema and chest tightness. Five months ago she diagnosed as Castlman's disease-plasma cell type, of retroperitoneal lymph node enlargement. The patient was followed up through outpatient department without any specific medication. Physical examination showed pale conjunctivae, palpable mass on epigastric area and pretibial pitting edema. The hemoglobin, leukocyte count and erythrocyte sedimentation rate were 96 g/L, 5.9×109/L and 127 mm/hour, respectively. The blood urea nitogen was 3.6 mmol/L and creatinine was 88 umol/L. The urinalysis showed 3 positive for albumin. Twentyfour hour urine contained 16.6 grams of protein. A computerized tomographic (CT) scan of the abdomen disclosed multiple lymph node enlargement at mesentery. Percutaneous needle biopsy of kidney showed massive infiltration of pale pinkish amorphous material in the glomerular tuft forming large nodules. Ultrastructural examination exhibited heavy deposition of amyloid fibrils in the mesangium and perpendicular to glomerular basement membrane. Polarizing microscopy with Congo-red stain revealed prominent yellow green birefringence in glomeruli, tubules and interstitium.

한국형 출혈열 후유증으로 발생된 만성 신우신염

김연수,한진석,이정상,김성권,진호준,안규리,오국환,오윤규 대한내과학회 1997 대한내과학회지 Vol.52 No.4

It has been known that most patients with Korean Hemorrhagic Fever (KHF) were recovered without any significant renal complication. But several cases of renal hypertension, chronic pyelonephritis, and chronic renal failure after KHF have been reported. Recently, we experienced one case of chronic pyelonephritis as a sequela of KHF, which has been diagnosed at the 78th month of illness. This case showed reduced thickness of renal parenchyme, small and irregular shaped kidney, focal loss of normal cupping of calyces, and accumulation of radiacontrast media at distal calyes by IVP. This case suggested that chronic pyelonephritis may develop as a sequela of KHF,

소아마취의 임상통계학적 고찰

김완식,박동호,황영희,김흥대,안기량,석민호,김지영,장경덕,서병태 대한마취과학회 1982 Korean Journal of Anesthesiology Vol.15 No.1

Midazolam maleate, a water soluble banzodiazepine unlike diazepam, was synthetized by Walser and Fryer in 1975. In order to ealuate the effectiveness as an induction agent for general anesthesia, 22 elective surgical patients belonging to ASA classification 1 and 2 were selected. And ten patients (male 7, female 3, average 33.5 years old) were induced with midazolam maleate 0.2mg/kg and twelve patients (mdale 7, female 5, average 32.5 years old) with diazepam 0.3mg/kg. The results were summarized as follows. 1) Anesthesia was induced in all of midazolam group by one intravenous injection, but only 6 patients of diazepam group could induced by one injection and the other 6 patients needed 2 or more injections. 2) The changes of blood pressure and pulse rate after induction and intubation were almost similar in the two groups, but greater individual variation was seen in diazepam group. 3) A buring sensation following intravenous injection was noted in 11 cases of diazepam group, but none in midazolam group and no phlebitis in either group. From the above results, diazepam and midazolam are almost similar in nature but midazolam is definitely effective as an induction agent and has less side effects. Therefore midazolam maleate is regarded as a more effective agent than diazepam as an induction for general anesthesia.

당뇨성망막증에서의 방사성핵종 망막신티그라피의 이용에 관한 연구

이상우,박영태,이형호,최승환,안일민,서순규,진용한,이태수 대한당뇨병학회 1985 Diabetes and Metabolism Journal Vol.9 No.1

흉막염환자에 있어서 흉막액 Adenosine Deaminase 활성도의 임상적 의의

이장훈,김성규,안철민,장상호,손희영,김기호 대한내과학회 1986 대한내과학회지 Vol.31 No.6

A clinical observasion was done on 145 cases of the various pleural effusions admitted to Yonsei University Hospital from Mar. 1984 to Mar. 1986, The pleural effusions were due to tuberculosis(76 cases), suspected tuberculosis(18 cases), malignancy(16 cases), suspected malignancy(22 cases), empyema or pneumonia(10 cases), miscellaneous (3 cases). We have measured the ADA activity of pleural fluids in each cases and the results were as follows. 1) In the tuberculous pleural effusion, the ADA activity of pleural fluid was significantly higher than that in the malignant pleural effusion. 2) There was no difference between the activities of pleural fluid ADA in the tuberculous pleural effusion and that in the suspected tuberculous pleural effusion. 3) If the cut-off value of pleural fluid ADA activity is 40U/L, the sensitivity was 90.4% and the specificity was 86.3% in the dignosis the tuberculous pleural effusion. It is suggested that the measurement of ADA activity in pleural effusion is of value in the differential diagnosis of patients with tuberculous pleurisy from those with malignant pleurisy and others, particularly when the results of other laboratory and clinical tests are negative, if the value is over 40 U/L.

Atropine과 Neostigmine이 심박수 및 심전도에 미치는 영향

김영석,김완식,김인규,박동호,황영희,안기량 대한마취과학회 1979 Korean Journal of Anesthesiology Vol.12 No.2

Four modes of administrating atropine and neostigmine to reverse pancuronium block were studied in thirty-eight anesthetized patients, with special referance to their effects on heart rate and electrocardiogram. At the end of operation in group 1 a mixture of atropine (0. 5 mg) and neostigmine(1. 0 mg) was rapidly injected together. In group 2 the same mixture was slowly injected in 3 minutes. In group 3 atropine was rapidly injected and 2 minutes later neostigmine was rapidly injected. In group 4 neostigmine was slowly injected in 1 minute and then immediately atropine was rapidly injected. The results were as follows. 1) In all groups a transient increase in heart rate was followed by a decrease which continued over 30 minutes. 2) The changes in heart rate were most pronounced when atropine was given before neostigmin(group 3) On the ther hand when atropine was given immediately after neostigmine the changes in heart rate seemed to be smallest. 3) A small number of cases showed transient ECG changes in each group. It is considered that one must be careful about arterial gas and ECG changes although the number of cases is small and certain correlation was not indicated but the ECG of the five of 38 patients are abnormal, four of these are among the abnormal cases in the gas study, two of the four abnormals are under PaO₂, 60 mmHg.

전신 마취중 Sodium Nitroprusside 가 중심동맥압과 심박수에 미치는 영향

이명애,주경란,김혜경,김병두,안창근 대한마취과학회 1980 Korean Journal of Anesthesiology Vol.13 No.4

The time course and magnitude of change in mean arterial pressure (MAP) and heart rate (HR) following a single rapid intravenous injection of 1ug/kg and 2ug/kg of sodium nitro prusside(SNP) were determined in 10 anesthetized patients. The results were as follows: 1) MAP began to decrease 15 seconds after both 1ug/kg and 2ug/kg of SNP and was maximal after 90 seconds with return toward control apparent by 3 minutes and complete after 5 to 6 minutes(Fig. 1). 2) The magnitude of decrease in MAP after SNP was dose related whereas onset and duration of blood pressure changes were not influenced by the SNP dose. 3) HR did not change significantly after either dose of SNP. SNP is a potent, rapid acting antihypertensive drug which produces arteriolar vasodilation and prevention of hypertension and is particularly important in patients with decreased myocardial reserve or intracranial pathology.

경막외마취 확산의 비교관찰 제 1 보 Bupivacaine-Lidocaine

김영석,김완식,김인규,김흥대,안기량,김교상 대한마취과학회 1980 Korean Journal of Anesthesiology Vol.13 No.1

Epidural anesthesia is widely practiced for lower abdominal operation and delivery in many hospital and its complication in minimal compared with spinal anesthesia. Lidocaine has been used extensively for epidural anesthesia with very satisfactory results. It has a very rapid onset of action, producing complete analgesia and has a reasonable duration of action(about 1-1½hr). A concentration of 1. 5% lidocaine causes effective sensory and autonomic blockade but it is unlikely to produce motor paralysis. More recently, bupivacaine(0.5%) has tended to supplement lidocaine as the drug of choice of epidural anesthesia. Firstly, the duration of action is longer. Secondly, it has better affinity for the tissue so that less will be absorbed into the circulation, thus reducing the risk of a toxic reaction. Thirdly, when used with a continuous technique, there is much chance of tachyphylaxis. Using a standardized anesthesia technic, we compared level of sensory anesthesia with a 0. 5% bupivacaine and 1. 5% lidocaine uder elective and emergency surgery. When equal volume of local anesthetic solution were injected(20 ml of 0.5% bupivacaine and l. 5% lidocaine) there were no statistically significant differences in sensory level in bupivacaine and lidocaine, but the duration of anesthesia in bupivacaine from 2 to 3 times longer than lidocaine.