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RISS 인기검색어
- 검색키워드
- 저자 : Azidah Abdul Kadir (검색결과 4 건)
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Abdul Kadir Azidah,Abdul Kadir Arifah,A. H. Roslida,Abdul Manan Mat Jais,Julia Omar,Abdul Nawfar Sadagatullah,Azlina Ishak,Norhayati Mohd. Noor,Ahmad Tarmizi Musa 경희대학교 융합한의과학연구소 2017 Oriental Pharmacy and Experimental Medicine Vol.17 No.4
Knee osteoarthritis (OA) is the leading cause of chronic disability at older age. Channa striatus (CS) is a freshwater fish that is traditionally valued for its medicinal properties in promoting wound healing and reducing post-operative pain. This study evaluate the efficacy of different doses of oral Channa striatus extract on primary knee osteoarthritis patients. A randomized, double-blind, placebo-controlled 3-arm trial was conducted comparing oral CS extract 1000 mg/day or 500 mg/day and placebo among knee OA patients for a 6-month intervention period. The main outcome measures were Western Ontario and McMaster University Osteoarthritis Index (WOMAC), analgesic scores and serum cartilage oligomeric matric protein (COMP). Laboratory-based blood tests were used as safety measures. A total of 120 patients were randomized, and 112 patients were included in the intention-to-treat analysis. Significant reductions in WOMAC stiffness and function scores were achieved at month 6 in CS 1000 mg/day and CS 500 mg/day compared to placebo groups (p < 0.05). No significant differences were found between the groups in terms of analgesic scores, serum COMP and biochemical parameters. No serious adverse events were reported in the study. In conclusion, both doses of CS showed similar efficacy and were more effective than the placebo in treating the symptoms of knee OA.
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Atirah Az-Zahrah Abu Bakar,Azidah Abdul Kadir,Nur Suhaila Idris 대한가정의학회 2021 Korean Journal of Family Medicine Vol.42 No.5
This case illustrates the medical complication of a child that arose as a consequence of parents with intellectual disabilities in a primary care setting. A 9-month-old girl presented with multiple admissions because of recurrent pneumonia and was later diagnosed with failure to thrive based on child neglect resulting from the parents’ disabilities. This exemplifies a failure to thrive case with a complex and undiagnosed psychosocial background that required interdepartmental involvement to mitigate the health problem.
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Efficacy and Safety of Labisia pumila var alata Water Extract Among Pre- and Postmenopausal Women
Mohd Noor Norhayati,Annie George,Nik Hussain Nik Hazlina,Abdul Kadir Azidah,Hassan Intan Idiana,Kim Sooi Law,Ismail Shaiful Bahari,Wan Mohamed Wan Zahiruddin,Eckehard Liske,Abas Azreena 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.8
This study evaluated the effectiveness and safety of Labisia pumila var alata (L. pumila) water extract for improving quality of life, cardiovascular and hormonal balance. A randomized, double-blind, placebo-controlled, parallel group, 16-week study in healthy pre- and postmenopausal women aged 40–60 years was conducted in Kelantan, Malaysia. The subjects were randomized to 400mg propriety extract of L. pumila or placebo. A Women’s Health Questionnaire was used to assess quality of life. Repeated-measures analysis of variance was used to evaluate the data. A total of 197 subjects (L. pumila: n = 102 and placebo: n = 95) were analyzed. Subjects in the herbal group showed improved memory/concentration, vasomotor symptoms, menstrual symptoms, and sleep problems by 8.3%, 15.9%, 11.8%, and 31.0%, respectively. The greatest improvement was observed for the question: ‘‘I get frightened or panic feelings for apparently no reason at all’’ with a 53% decrease as compared with placebo. Improvements were also seen in the cardiovascular parameters, and the safety profiles were normal. Postmenopausal women supplemented with L. pumila showed no changes in gynecological relevant hormones luteinizing hormone (LH), folliclestimulating hormone (FSH), and 17b-Estradiol.Water extract of L. pumila was shown to be safe and effective for improving several parameters of quality of life and cardiovascular risks factors (total cholesterol [TC], low-density lipoprotein cholesterol [LDL-C]).
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Bathma Dhevi Susibalan,Baharudin Abdullah,Norhafiza Mat Lazim,Azidah Abdul Kadir 경희대학교 융합한의과학연구소 2018 Oriental Pharmacy and Experimental Medicine Vol.18 No.3
Allergic rhinitis is a prevailing chronic infl ammatory respiratory disorder that aff ects 10–30% of the population globally. Channa striatus (Channa) is a snakehead, freshwater fi sh that has been used traditionally to enhance wound healing and relief post-operative pain. This study evaluates the effi cacy of oral Channa extract on allergic rhinitis subjects on total nasal symptom score and serum immunoglobulin E (Ig E). A randomized, double-blind, placebo-controlled trial was conducted by comparing the oral Channa extract 500 mg/day and placebo among allergic rhinitis subjects for a 6-week intervention period. Subjects aged 18–50 years old, diagnosed with allergic rhinitis based on total symptoms score, naso-endoscopy fi ndings, and positive skin prick test were included in this trial. All subjects were treated with antihistamine (levocetrizine) and local corticosteroid nasal spray (fl uticasone furoate nasal spray). Laboratory-based blood tests were used as safety measures. A total of 70 subjects were randomized. Channa group showed signifi cant improvement in nasal blockage ( p < 0.05), nasal itchiness ( p < 0.05), eye itchiness ( p < 0.05) and general symptoms ( p < 0.05) compared to the placebo groups. Serum Ig E were signifi cantly lowered in Channa group compared to placebo ( p < 0.001). No signifi cant diff erences were found between the groups in terms of nasal discharge, sneezing, palate itchiness, and smell score. No serious adverse events were reported. In conclusion, Channa has a benefi cial role in improving nasal symptoms and reduction in serum Ig E in allergic rhinitis subjects.
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