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RISS 인기검색어
- 검색키워드
- 저자 : Nik Hussain Nik Hazlina (검색결과 4 건)
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Metoclopramide for Milk Production in Lactating Women: A Systematic Review and Meta-Analysis
Nik Hazlina Nik Hussain,Norhayati Mohd. Noor,Shaiful Bahari Ismail,Nur Amirah Zainuddin,Zaharah Sulaiman 대한가정의학회 2021 Korean Journal of Family Medicine Vol.42 No.6
Background: Breastfeeding is recognized as the optimal form of nutrition for the physical and neurological devel-opment of infants and is considered the most significant way to prevent child mortality. This study aimed to assess the effectiveness of metoclopramide for enhancing milk production in lactating women.Methods: We searched the Cochrane Central Register of Controlled Trials and MEDLINE for randomized con-trolled trials comparing metoclopramide with a placebo, no treatment, or other galactagogue drugs. We included breastfeeding women with term or preterm infants.Results: We retrieved 164 records from our search of the electronic databases and 20 records from other sources. Eight trials involving 342 lactating women that used metoclopramide were included in this review after assessing the eligibility criteria. The meta-analysis of these trials revealed that metoclopramide did not increase the milk vol-ume of the intervention groups compared to that of the control groups. There was a significant increase in the se-rum concentrations of prolactin when the mothers were administered metoclopramide. No significant adverse events were reported.Conclusion: Metoclopramide did not improve milk production in lactating women. Therefore, we do not recom-mend using metoclopramide to increase milk production in lactating women.
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Othman, Nor Hayati,Zaki, Fatma Hariati Mohamad,Hussain, Nik Hazlina Nik,Yusoff, Wan Zahanim Wan,Ismail, Pazuddin Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.7
Background: A major problem with cervical cancer screening in countries which have no organized national screening program for cervical cancer is sub-optimal participation. Implementation of self-sampling method may increase the coverage. Objective: We determined the agreement of cytological diagnoses made on samples collected by women themselves (self-sampling) versus samples collected by physicians (Physician sampling). Materials and Methods: We invited women volunteers to undergo two procedures; cervical self-sampling using the Evalyn brush and physician sampling using a Cervex brush. The women were shown a video presentation on how to take their own cervical samples before the procedure. The samples taken by physicians were taken as per routine testing (Gold Standard). All samples were subjected to Thin Prep monolayer smears. The diagnoses made were according to the Bethesda classification. The results from these two sampling methods were analysed and compared. Results: A total of 367 women were recruited into the study, ranging from 22 to 65 years age. There was a significant good agreement of the cytological diagnoses made on the samples from the two sampling methods with the Kappa value of 0.568 (p=0.040). Using the cytological smears taken by physicians as the gold standard, the sensitivity of self-sampling was 71.9% (95% CI:70.9-72.8), the specificity was 86.6% (95% CI:85.7-87.5), the positive predictive value was 74.2% (95% CI:73.3-75.1) and the negative predictive value was 85.1% (95% CI: 84.2-86.0). Self-sampling smears (22.9%) allowed detection of micro-organisms better than physicians samples (18.5%). Conclusions: This study shows that samples taken by women themselves (self-sampling) and physicians have good diagnostic agreement. Self-sampling could be the method of choice in countries in which the coverage of women attending clinics for screening for cervical cancer is poor.
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Efficacy and Safety of Labisia pumila var alata Water Extract Among Pre- and Postmenopausal Women
Mohd Noor Norhayati,Annie George,Nik Hussain Nik Hazlina,Abdul Kadir Azidah,Hassan Intan Idiana,Kim Sooi Law,Ismail Shaiful Bahari,Wan Mohamed Wan Zahiruddin,Eckehard Liske,Abas Azreena 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.8
This study evaluated the effectiveness and safety of Labisia pumila var alata (L. pumila) water extract for improving quality of life, cardiovascular and hormonal balance. A randomized, double-blind, placebo-controlled, parallel group, 16-week study in healthy pre- and postmenopausal women aged 40–60 years was conducted in Kelantan, Malaysia. The subjects were randomized to 400mg propriety extract of L. pumila or placebo. A Women’s Health Questionnaire was used to assess quality of life. Repeated-measures analysis of variance was used to evaluate the data. A total of 197 subjects (L. pumila: n = 102 and placebo: n = 95) were analyzed. Subjects in the herbal group showed improved memory/concentration, vasomotor symptoms, menstrual symptoms, and sleep problems by 8.3%, 15.9%, 11.8%, and 31.0%, respectively. The greatest improvement was observed for the question: ‘‘I get frightened or panic feelings for apparently no reason at all’’ with a 53% decrease as compared with placebo. Improvements were also seen in the cardiovascular parameters, and the safety profiles were normal. Postmenopausal women supplemented with L. pumila showed no changes in gynecological relevant hormones luteinizing hormone (LH), folliclestimulating hormone (FSH), and 17b-Estradiol.Water extract of L. pumila was shown to be safe and effective for improving several parameters of quality of life and cardiovascular risks factors (total cholesterol [TC], low-density lipoprotein cholesterol [LDL-C]).
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Zaharah Sulaiman,Norhayati Mohd Noor,Shaiful Bahari Ismail,Anis Syahirah Far’ain Mohd Lukman,Muhammad Irfan,Nik Hazlina Nik Hussain 대한가정의학회 2022 Korean Journal of Family Medicine Vol.43 No.3
Background: Vitamin D may enhance immune system function and provide a protective effect against infections. Feto-maternal circulation plays an important role in supplying the developing fetus with nutrients and antibodies for its development and health during pregnancy and for its early years of life after birth. This meta-analysis aimed to determine the effectiveness of maternal vitamin D supplementation in preventing respiratory tract infections (RTIs) in children.Methods: We searched the Central and MEDLINE databases and went through all the reference lists in the related articles. We also searched for ongoing trials at http://www.who.int/ictrp/en/ and www.clinicaltrials.gov. Random-ized controlled trials comparing vitamin D supplementation with a placebo or no treatment in pregnant women published in the English language up to March 2019 were included. Two reviewers extracted data independently using a predefined protocol and assessed the risk of bias using the Cochrane risk of bias tool, with differences agreed upon by consensus. The predefined primary outcome was the number of offspring who had RTIs. The sec-ondary outcome was the presence of measurable serum immunoglobulin E levels.Results: Three trials involving 3,224 participants (mother–child pairs) met the inclusion criteria and were included in this review. The present analysis reported that maternal supplementation with vitamin D had no effect on RTIs among children (n=1,486 offspring; risk ratio, 0.95; 95% confidence interval, 0.82–1.11; random effects; I2 statistics, 0%).Conclusion: Maternal vitamin D supplementation had no effect on RTIs in children. Therefore, consideration of other prevention methods in this regard is recommended.
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