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Anju Maharjan,JiHun Jo,Manju Acharya,SuJeong Yang,Ravi Gautam,Sojung Sin,Hyocher Kim,ChangYul Kim,Yong Heo,HyoungAh Kim 계명대학교 자연과학연구소 2020 Quantitative Bio-Science Vol.39 No.2
The paradigm of immune homeostasis between type-1 helper T cells (Th1) and type-2 helper T cells (Th2) has been extensively examined with respect to infectious diseases, autoimmune diseases, or tumor progression. Such studies have mostly relied on the profiling of cytokines/chemokines using animal studies or cell culture-based in vitro tests. No quantitative analyses have yet been systematically performed to determine the relationship between the various immune parameters in in vivo investigations. Using peripheral blood from 55 chicken husbandry workers or grapevine orchard workers, we obtained data for various immunologic markers as follows: proportion of major immune cell subpopulations, concentrations of plasma immunoglobulin subclasses, and levels of cytokines produced from activated peripheral blood mononuclear cells. Correlational analyses were carried out to examine the association between these parameters. As the IFN-γ:IL-13 ratio was strongly associated with the production levels of IFN-γ, TNF-α, and to the IFN-γ:IL-4 ratio, the IFN-γ:IL-13 ratio could prove to be a valuable monitoring index to examine Th1 or Th2 predominance. IL-17 levels correlated well with those of IFN-γ or TNF-α. Plasma levels of IgG4, a typical IgG subclass expressed upon the occurrence of allergic diseases, strongly correlated with IgG1 levels, suggesting the implication of IgG1 in allergic hyperreactivity. The proportion of cytotoxic T cells correlated significantly with levels of IFN-γ, and the proportion of natural killer T cells correlated well with IL-13 levels. These two cell types are sources for the production of IFN-γ and IL-3 respectively; hence, results of this study might provide potential monitoring markers for cytotoxic T cells or natural killer T cell-mediated immunoreactivity. Overall, the present study provides several putative candidates for the surveillance or prognosis of the in vivo alteration of humoral or cell-mediated immunity.
Characteristic white light emission via down-conversion SrGdAlO4:Dy3+ nanophosphor
Anju Hooda,S.P. Khatkar,Avni Khatkar,Sangeeta Chahar,Sushma Devi,Jyoti Dalal,V.B. Taxak 한국물리학회 2019 Current Applied Physics Vol.19 No.4
An efficient and cost-effective technique, solution combustion synthesis was used to synthesize Dy3+ doped SrGdAlO4 nanophosphor utilizing urea as a suitable fuel. The tetragonal phase and nano-crystallinity of the synthesized phosphor belonging to I4/mmm space group was confirmed by powder X-ray diffraction (PXRD) and transmission electron microscope (TEM) technique respectively. Various crystal structure parameters and refined atomic positions of host matrix and SrGd0.95Dy0.05AlO4 nanophosphor were determined by Rietveld refinement. The two intense bands i.e. blue and yellow bands were observed in photoluminescence emission spectrum recorded at 352 nm excitation wavelength, associated to transitions 4F9/2→6H15/2 (484 nm) and 4F9/2→6H13/2 (575 nm) respectively. Photometric characterizations revealed the emission of white color by the synthesized nanophosphor proving its wide applications in WLEDs (white light emitting diodes). Band gap values calculated using diffuse reflectance spectra (DRS) were found to vary in the range of 5.50 eV–5.59 eV for host and doped lattice system. Keeping in mind, the concentration quenching phenomenon, SrGd0.95Dy0.05AlO4 was considered as optimized nanophosphor for WLEDs.
Anju Sasidharan,Nishanth Kumar Sasidharan,Dileepkumar Bhaskaran Nair Saraswathy Amma,Radhakrishnan Kokkuvayil Vasu,Anupama Vijaya Nataraja,Krishnakumar Bhaskaran 한국미생물학회 2015 The journal of microbiology Vol.53 No.10
A novel strain of Chromobacterium sp. NIIST (MTCC 5522) producing high level of purple blue bioactive compound violacein was isolated from clay mine acidic sediment. During 24 h aerobic incubation in modified Luria Bertani medium, around 0.6 g crude violacein was produced per gram of dry weight biomass. An inexpensive method for preparing crystalline, pure violacein from crude pigment was developed (12.8 mg violacein/L) and the pure compound was characterized by different spectrometric methods. The violacein prepared was found effective against a number of plant and human pathogenic fungi and yeast species such as Cryptococcus gastricus, Trichophyton rubrum, Fusarium oxysporum, Rhizoctonia solani, Aspergillus flavus, Penicillium expansum, and Candida albicans. The best activity was recorded against Trichophyton rubrum (2 μg/ml), a human pathogen responsible for causing athlete’s foot infection. This is the first report of antifungal activity of purified violacein against pathogenic fungi and yeast.
Growing teratoma syndrome in a post laparoscopic excision of ovarian immature teratoma
Anju Rani Sengar,Jagdeesh Narhar Kulkarni 대한부인종양학회 2010 Journal of Gynecologic Oncology Vol.21 No.2
A 26-year-old girl was referred to us in December 2008 with progressive pelvic mass while on chemotherapy. In May 2008, she presented with large adnexal mass and high alpha-fetoprotein (AFP, 265.7 ng/mL; normal range, 0 to 10). She underwent laparoscopic right salpingo-oophorectomy with staging. Since histology was immature teratoma grade I, FIGO stage 1 she was kept on surveillance. In September 2008, she developed recurrent pelvic mass with AFP levels of 2,400 ng/mL. Three courses of chemotherapy (bleomycin-etoposide-cisplatin) were given. Post-chemotherapy AFP normalized but tumor size increased. CT-scan (abdomen-pelvis) showed a large pelvic mass with calcification specks;infiltrating the sigmoid colon and abdominal wall. With provisional diagnosis of growing teratoma syndrome she had exploratory laparotomy with excision of pelvic mass along with sigmoid colon, excision of right pelvic and subcutaneous deposits, omentectomy and sigmoid anastomosis. Left ovary, left tube and uterus appeared normal and were preserved. Histology of all masses showed mature teratoma, no immature elements. At six months follow up she is disease free and has resumed menstruation. Growing teratoma syndrome is a clinico-pathological presentation during/post-chemotherapy in malignant ovarian germ cell tumor where mature teratoma grows and requires complete surgical excision. Our case highlights the safety and adequacy concerns of laparoscopic management of malignant ovarian tumor. Literature review suggests good prospects of resumption of menses, child bearing and five year survival in case of growing teratoma syndrome.
The Present Situation of Information Services for Women in India
Anju Vyas Asian pacific women's information network center 1999 APWIN Vol.1 No.-
With this brief overview an attempt is made to present a glimpse of the current scenario of information services in India in the context of research and academic needs as well as every day information needs of women. It is evident that though a beginning has been made in both the directions, there are still considerable gaps in the services being provided which need to be taken care of. Standing on the threshold of the new century we should spare a little time for introspection and self-assessment. As information professionals have, we succeeded in helping the right user at the right time! Why is that still the most commonly expressed feeling at all women's studies forum is about the lack of women's information? Is it a lack of information itself or access to it or both? Is there a lack of dialogue among those who generate information, those who collect, organize, and provide it and those who want it, i.e. the end users? Are our present information sources and services inadequate? Also have we not been too elitist in our approach to information by leaving out the majority of the users, the women at the grassroots disserved? Are we going to be a party to the process of further marginalization of rural women by promoting the use of new technology to which they have no access what so ever? Some of these concerns must be addressed while planning future strategies.