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RISS 인기검색어
- 검색키워드
- 저자 : Sushma Devi (검색결과 4 건)
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Sushma, C,Prasad, Shiva,Devi, Rudrama,Murthy, Sudha,Rao, TS,Naidu, CK Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8
Background: Ras genes are thought to play an important role in human cancer since they have been found to be activated frequently in several types of tumors including breast cancer, where the overall incidence of K-RAS oncogene activation is 0-10%. Evaluation of K-RAS gene not only for mutational frequency but also for mutation types in this downstream signaling gene pathway is necessary to determine the mechanisms of action. The present study was conducted to test the hypothesis that K-RAS activation is involved in breast cancer risk of south Indian population. Materials and Methods: A total of 70 paired pathologically confirmed tumor and non-tumor tissues from the same breast cancer patients were analysed for most common K-RAS mutations of codon 12,13 and 61 by polymerase chain reaction followed by restriction digestion and direct nucleotide sequencing method. Results: We found that a high rate of homozygous and heterozygous mutations of codon 12, but not codon 13 and 61, may influence the invasive ductal carcinoma of breast risk in this study. Conclusions: Our study indicated that only codon 12 may be involved in initiating breast carcinogenesis in India.
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B. Vikram Babu,M. Sushma Reddi,A. Rama Krishna,B. Sathish Mohan,G. Chandana,K. Anjani Devi,B. Sridhar,K. Samatha 한국전기전자재료학회 2022 Transactions on Electrical and Electronic Material Vol.23 No.5
This research article aims at reporting the influence of magnesium by studying the structural, electrical impedance and modulus properties of the Mg substituted Li 4 Ti 5 O 12 . These studies are useful for the electrochemical properties. The XRD reveals that the structure of all the Mg substituted materials belongs to the cubic spinel group having Fd-3m space symmetry. SEM images display the structural, morphological properties with the average size of grains falling in the vicinity of 1 μm. The electrical impedance of Li 4− x Mg x Ti 5 O 12 materials was analyzed at frequencies between 20 Hz and 1 MHz and in the 30–120 °C range of temperature by employing the complex impedance spectroscopy (CIS) method. The modulus formalism is also a suitable tool to understand the dynamical characteristics of electrical transport phenomena. The complex electric modulus spectrum signifi es quantifying the allocation of ion energies or confi gurations in the lattice. Also, it portrays the electrical relaxation of ion-conducting lattices as a feature of materials at a minuscule level. The obtained results of substitution of Mg in Li 4 Ti 5 O 12 anode materials improve the potential applications of conductivity and charge/discharge performance.
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Pokharel Basanta Raj,Pandey Sushma,Manandhar Mangala Devi,Pant Bijaya 한국식물생명공학회 2023 Plant biotechnology reports Vol.17 No.3
Comparative analysis was carried out to determine the variation in the composition of essential oils of hairy roots produced in vitro and in vivo rhizomes of Valeriana jatamansi Jones collected from three different districts in Nepal i.e., Pyuthan (1200 m), Gulmi (3000 m), Godawari (1400 m) was carried out. In vitro adventitious root proliferation was established in MS media supplemented with Naphthalene acetic acid (NAA). GC–MS analysis were performed on the essential oils extracted from the sample. The findings showed that the yield of the essential oil obtained from the hydrodistillation of in vitro adventitious roots and dried rhizomes ranged between 0.52 and 0.80%. The highest percentage of essential oil (0.80%) were produced in the in vitro adventitious roots and minimum in the in vivo rhizomes collected from Pyuthan district, i.e., (0.52%). GC–MS analysis revealed a total of 17 volatile compounds in the essential oil from the dried rhizomes of V. jatamansi Jones from different locations and in vitro adventitious roots. It was found that the compound carotol was present only in sample from Pyuthan district, but absent in other samples. The compound matricarin was found in samples from Gulmi and Godawari district but absent in samples from Pyuthan district and in vitro adventitious roots. Similarly, the compound jatamansone was found in samples from Gulmi, Godawari, and adventitious roots but absent in sample from Pyuthan district. The compounds patchoulinone, 1, 2-butyl octyl ester of benzene dicarboxylic acid, and bis (2-ethyl hexyl) phthalate, one of the major compounds were present only in sample from adventitious roots The findings of the present study showed that the essential oil composition in both in vitro and in vivo roots, at different altitudes significantly affect the essential oil content of V. jatamansi Jones.
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Characteristic white light emission via down-conversion SrGdAlO4:Dy3+ nanophosphor
Anju Hooda,S.P. Khatkar,Avni Khatkar,Sangeeta Chahar,Sushma Devi,Jyoti Dalal,V.B. Taxak 한국물리학회 2019 Current Applied Physics Vol.19 No.4
An efficient and cost-effective technique, solution combustion synthesis was used to synthesize Dy3+ doped SrGdAlO4 nanophosphor utilizing urea as a suitable fuel. The tetragonal phase and nano-crystallinity of the synthesized phosphor belonging to I4/mmm space group was confirmed by powder X-ray diffraction (PXRD) and transmission electron microscope (TEM) technique respectively. Various crystal structure parameters and refined atomic positions of host matrix and SrGd0.95Dy0.05AlO4 nanophosphor were determined by Rietveld refinement. The two intense bands i.e. blue and yellow bands were observed in photoluminescence emission spectrum recorded at 352 nm excitation wavelength, associated to transitions 4F9/2→6H15/2 (484 nm) and 4F9/2→6H13/2 (575 nm) respectively. Photometric characterizations revealed the emission of white color by the synthesized nanophosphor proving its wide applications in WLEDs (white light emitting diodes). Band gap values calculated using diffuse reflectance spectra (DRS) were found to vary in the range of 5.50 eV–5.59 eV for host and doped lattice system. Keeping in mind, the concentration quenching phenomenon, SrGd0.95Dy0.05AlO4 was considered as optimized nanophosphor for WLEDs.
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