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Design and Performance Study of a Hot Water Driven 5 TR Capacity Absorption Cooling System
Anil Sharma,Bimal Kumar Mishra,Abhinav Dinesh,Ashok Misra 보안공학연구지원센터 2014 International Journal of u- and e- Service, Scienc Vol.7 No.6
Use of high grade electrical energy, generated from fossil fuels, for cooling has increased environmental concerns like global warming and ozone layer depletion. Hence, there is a need to reduce dependence on them and explore potential environmental friendly options. In this aspect, vapor absorption system has scope of utilizing low grade energy source i.e. hot water from solar panel, to generate cooling effect and are environment friendly as no chloro-floro-carbons are used. The most usual combination of absorber refrigerant pair in such system is lithium bromide water (LiBr–H2O), where water vapor is the refrigerant. In present work, a hot water driven, single stage, absorption cooling system, using a lithium bromide water solution, is analyzed for determining the effect of various parameters on coefficient of performance (COP). Four basic stages in the absorption cycle are generation, condensation, evaporation and absorption with ideally no moving part. A configuration of theses four stages, having 5 TR cooling capacity is determined and examined for the variation in COP corresponds to the change in pressure and concentration. The pressure parameter is varied in condenser and evaporator, resulting graph shows that the increment in pressure of evaporator increases the COP whereas increment of pressure in condenser decreases the COP. At lower inlet concentration of LiBr solution to the absorber gives increment in COP.
Dewan, Abhinav,Sharma, SK,Dewan, AK.,Srivastava, Himanshu,Rawat, Sheh,Kakria, Anjali,Mishra, Maninder,Suresh, T,Mehrotra, Krati Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
Objective of the study is to evaluate volumetric and dosimetric alterations taking place during radiotherapy for locally advanced head and neck cancer (LAHNC) and to assess benefit of replanning in them. Materials and Methods: Thirty patients with LAHNC fulfilling the inclusion and exclusion criteria were enrolled in a prospective study. Planning scans were acquired both pre-treatment and after 20 fractions (mid-course) of radiotherapy. Single plan (OPLAN) based on initial CT scan was generated and executed for entire treatment course. Beam configuration of OPLAN was applied to anatomy of interim scan and a hybrid plan (HPLAN30) was generated. Adaptive replanning (RPLAN30) for remaining fractions was done and dose distribution with and without replanning compared for remaining fractions. Results: Substantial shrinkage of target volume (TV) and parotids after 4 weeks of radiotherapy was reported (p<0.05). No significant difference between planned and delivered doses was seen for remaining fractions. Hybrid plans showed increase in delivered dose to spinal cord and parotids for remaining fractions. Interim replanning improved homogeneity of treatment plan and significantly reduced doses to cord (Dmax, D2% and D1%) and ipsilateral parotid (D33%, D50% and D66%) (p<0.05). Conclusions: Use of one or two mid-treatment CT scans and replanning provides greater normal tissue sparing along with improved TV coverage.
Singh, Renu,Sharma, Abhinav,Hong, Seongkyeol,Jang, Jaesung The Royal Society of Chemistry 2014 The Analyst Vol.139 No.21
<P>The influenza virus has received extensive attention due to the recent H1N1 pandemics originating from swine. This study reports a label-free, highly sensitive, and selective electrical immunosensor for the detection of influenza virus H1N1 based on dielectrophoretically deposited single-walled carbon nanotubes (SWCNTs). COOH-functionalized SWCNTs were deposited on a self-assembled monolayer of polyelectrolyte polydiallyldimethyl-ammonium chloride (PDDA) between two gold electrodes by dielectrophoretic and electrostatic forces, which resulted in reproducible, uniform, aligned, and aggregation-free SWCNT channels (2-10 mu m in length). Avidin was immobilized onto the PDDA-SWCNT channels, and viral antibodies were immobilized using biotin-avidin coupling. The resistance of the channels increased with the binding of the influenza viruses to the antibodies. These immunosensors showed linear behavior as the virus concentration was varied from 1 to 10(4) PFU ml(-1) along with a detection time of 30 min. The immunosensors with a 2 mu m channel length detected 1 PFU ml(-1) of the influenza virus accurately (R-2 = 0.99) and selectively from MS2 bacteriophages. These immunosensors have the potential to become an important component of a point-of-care test kit that will enable a rapid clinical diagnosis.</P>
Vinod Kumar Sharma,G. Srinivasa Rao,C. M. Bhatt,Abhinav Kumar Shukla,Ashish Kumar Mishra,V. Bhanumurthy 대한공간정보학회 2017 Spatial Information Research Vol.25 No.5
Value added flood products helps decision makers in an efficient relief and rescue operations. On time availability of flood products, may help decision makers, in early decision making. Indian monsoon causes floods in several Indian states at a time, every year. Mapping multiple states at a time needs lot of man power and expertise. Manual flood mapping process is a time consuming process. Automatic procedures, for delineating flood and generation of value added products from satellite images can reduce the critical time-span. In the present study, an attempt is made to automate the entire flood mapping chain. The prototype study, is demonstrated for the state of Assam and the modules developed are tested for the multiple flood events during the Brahmaputra floods of August–September, 2016. The modules are checked for each stage and their outputs are validated with those as derived from manual procedures. The study has demonstrated significant reduction in the turn out time for flood response, which is very important during rapid disaster response.
Bhardwaj, Jyoti,Sharma, Abhinav,Jang, Jaesung Elsevier Applied Science 2019 Biosensors & Bioelectronics Vol. No.
<P><B>Abstract</B></P> <P>We present a novel vertical flow-based paper immunosensor for the rapid and sensitive electrochemical and colorimetric detection of influenza H1N1 viruses using a different pore size (DP) sample pad. The DP sample pad consisted of two different pore size papers: larger pores (diameter: 11 µm) facing the inlet, and smaller pores (diameter: 0.45 µm) facing the conjugate pad. This sample pad offered moderate and uniform flows, and hence concentrated horseradish peroxidase tagged antibodies (HRP-Abs)-H1N1 complexes from 40 µL of sample volumes on a conjugate pad for 2 min after sample injection, thereby providing fast detection (6 min for both detection methods) with 100 µL of flushing afterwards, high sensitivity, and the simplicity of the sensor. The filtration characteristics of the DP sample pad were evaluated using fluorescent beads, indicating that only small-sized bio-particles such as viruses can pass through the sample pad. Sandwich immunoreactions of HRP-Ab-H1N1-Ab were performed on the gold paper electrode of the immunoStrip, which was determined by electrochemical impedance spectroscopy (EIS) measurements. Simultaneously, the color signal of free HRP-Ab captured on the colorimetric zone was obtained using a scanner, and the intensity was analyzed using ImageJ. This immunosensor detected H1N1 virus concentration as low as 3.3 plaque forming units (PFU)/mL (phosphate buffer saline; PBS) and 4.7 PFU/mL (saliva) by EIS, and 1.34 PFU/mL (PBS) and 2.27 PFU/mL (saliva) by the colorimetric method. Furthermore, integrating these two detection methods can reduce false results with double assurance, and this device can provide a simple and economical on-site detection platform.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The first paper immunosensor using a double pore size (DP) sample pad. </LI> <LI> The first vertical flow assay-based, sandwich ELISA-type paper immunosensor for the detection of influenza viruses. </LI> <LI> Dual (electrochemical and colorimetric) detection methods to provide double assurance. </LI> <LI> The DP sample pad offered fast detection (~6 min), high sensitivity (the limit of detection <5 PFU/mL), and the simplicity. </LI> <LI> The DP sample pad also acted as a filter to pass only small-sized particles. </LI> </UL> </P>
De-novo Gastrointestinal Anastomosis With Lumen Apposing Metal Stent
Deepanshu Jain,Ankit Chhoda,Abhinav Sharma,Shashideep Singhal 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.5
Gastric outlet obstruction, afferent or efferent limb obstruction, and biliary obstruction among patients with altered anatomy oftenrequire surgical intervention which is associated with significant morbidity and mortality. Endoscopic dilation for benign etiologiesrequires multiple sessions, whereas self-expandable metal stents used for malignant etiologies often fail due to tumor in-growth. Lumenapposing metal stents, placed endoscopically with the intent of creating a de-novo gastrointestinal anastomosis bypassing the site ofobstruction, can potentially achieve similar effcacy, with a much lower complication rate. In our study cohort (n=79), the compositetechnical success rate and clinical success rate was 91.1% (72/79) and 97.2% (70/72), respectively. Five different techniques were used:43% (34/79) underwent the balloon-assisted method, 27.9% (22/79) underwent endoscopic ultrasound-guided balloon occludedgastro-jejunostomy bypass, 20.3% (16/79) underwent the direct technique, 6.3% (5/79) underwent the hybrid rendezvous technique,and 2.5% (2/79) underwent natural orifice transluminal endoscopic surgery (NOTES)-assisted procedure. All techniques required anechoendoscope except NOTES. In all, 53.2% (42/79) had non-cautery enhanced Axios stent, 44.3% (35/79) had hot Axios stent, and2.5% (2/79) had Niti-S spaxus stent. Symptom-recurrence was seen in 2.8%, and 6.3% had a complication (bleeding, abdominal pain orperitonitis). All procedures were performed by experts at centers of excellence with adequate surgical back up.
On the Optical Properties of Ag+15 Ion-beam-irradiated TiO2 and SnO2 Thin Films
Hardeep Thakur,K. K. Sharma,Ravi Kumar,Pardeep Thakur,Yogesh Kumar,Abhinav Pratap Singh,Sanjeev Gautam,채근화 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.10
The effects of 200 MeV Ag<sup>+15</sup> ion irradiation on the optical properties of TiO<sub>2</sub> and SnO<sub>2</sub> thin films prepared by RF magnetron sputtering technique were investigated. These films were characterized by the UV-vis spectroscopy and it was observed that with increase in irradiation fluence the transmittance for the TiO<sub>2</sub> films systematically increases while that for SnO<sub>2</sub> decreases. Absorption spectra of the irradiated samples showed a minor changes in indirect bandgap from 3.44 to 3.59 eV for TiO<sub>2</sub> while that for SnO<sub>2</sub> significant modifications in the direct bandgap from 3.92 to 3.6 eV were observed on increasing irradiation fluence. The observed modifications in the optical properties of both TiO<sub>2</sub> and SnO<sub>2</sub> systems with irradiation can be attributed to controlled structural disorder/defects in the system.