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이진희(Jin hee Lee),김지연(Ji Yeon Kim),박상규(Sang Gyu Park),이재호(Jae Ho Lee),윤종호(Jong Ho Yoon),한기동(Gi Dong Han) 한국환경보건학회 2017 한국환경보건학회지 Vol.43 No.4
Objectives: The hazardous metals content of medicinal herbs distributed in the Daegu area was investigated, and the place of origin and the content of herbicides and medicinal components were studied. Methods: An analysis of hazardous metals content (10 types) was carried out on 164 samples of 99 types of herbal medicines. Among the total samples, 45 were domestic and 119 were imported. Hg was analyzed by the amalgamation method. Other hazardous metals content (nine types) was digested using the microwave method and measured by inductively coupled plasma optical emission spectrometry (ICP-OES). Results: The mean values of the hazardous metals content in the herbal medicines were Pb 1.0833 mg/kg, As 0.0136 mg/kg, Cd 0.0840 mg/kg, Cr 3.7120 mg/kg, Cu 4.2666 mg/kg, Mn 40.080 mg/kg, Ni 1.4330 mg/kg, Sb 0.1053 mg/kg, Al 202.64 mg/kg and Hg 0.0062 mg/kg. Three of the samples violated the Ministry of Food and Drug Safety (MFDS) regulatory guidance on cadmium (less than 0.3 mg/kg). The measured values of heavy metals (Pb, As, Cd, Hg) showed levels below the recommended levels for herbal medicines in MFDS regulatory guidance. In the comparison of domestic samples with imported herbal medicines, it was found that one domestic and two imported samples surpassed the maximum residue limits for cadmium. The median values of the hazardous metals detected in the three medicinal parts of the root, leaf (branch), and flower (seed and fruit) were as follows. Cr, Ni, Sb and Al were highly detected in roots, Pb, Cd, Mn, Hg in leafs (branch), and As, Cu in flowers (seed and fruit). Conclusion: There were various kinds of hazardous metals which were detected at high levels according to the place of origin of the medicinal herb and the parts the plant. For hazardous metals for which no acceptance criteria have been established, safety standards should be further studied and managed to ensure the safety of herbal medicines.
미이용 초본계 바이오매스 활용을 위한 반탄화 기술 리뷰
이다혜(Da-Hye Lee),강태진(Tae-Jin Kang),김효식(Hyo-Sik Kim),이진희(Jin-Hee Lee),이예지(Ye-Ji Lee),이수출(Soo-Chool Lee),강석환(Suk-Hwan Kang) 한국열환경공학회 2022 열환경공학 Vol.17 No.2
Biomass is a major carbon neutral energy source, but it is generally difficult to use as a fuel due to low energy density, high moisture content, and low heating value because of hydrophilicity. As one of the methods for overcoming these problems of biomass, research on torrefaction is continuously being performed. Through torrefaction, high energy density characteristics can be obtained by increasing the carbon content in the biomass, and moisture in the biomass can be removed, hydrophilicity can be changed to hydrophobicity, and the heating value can be increased. In addition, since a grindability of torrified biomass is improved, energy consumption is reduced 3 to 7 times when pulverizing biomass, thereby reducing costs of storage and transportation. In the domestic torrefied biomass market, laboratory-scale tests are being conducted in universities, but development for commercialization and demonstraion is still insignificant. In EU, demonstraion and commercial scale torrefaction technologies such as rotary drum, screw, moving bed, fluidized bed, multi-stage furnace, and conveyor belt types are being developed. This study analyzed the characteristics and R&D trends of biomass torrefaction technology, an upgrading fuel conversion technology from wasted herbaceous biomass for sustainable development.
수요자 중심의 건강검진 경험가치 향상을 위한 서비스 디자인 전략제안
이진희(Lee, Jin Hee),예동균(Ye, Dong Gyun),최아영(Choi, Ayoung),김지우(Kim, Ji Woo),구유리(Koo, Yoo Ri) 한국디자인문화학회 2021 한국디자인문화학회지 Vol.27 No.1
국내에서는 건강에 대한 높은 관심으로 건강검진의 중요성이 지속적으로 증가하고 있다. 늘어난 수요와 필요성에 따라 건강검진센터가 증가하고 있으나 외형적 투자로만 서비스 개선을 접근하여 외재적 변화는 가져왔지만 내재적이고 본질적인 수요자 중심의 서비스 디자인 개선은 아직까지 실현되지 못하고 있다. 따라서 본 연구의 목적은 수요자 중심의 건강검진 여정분석과 경험 가치에 근거한 디자인 개발과 검증과정을 거쳐 실증적인 건강검진서비스 디자인 전략을 제안하고자 한다. 본 연구는 크게 세단계로 구성된다. 먼저 사용자 경험가치 및 의료서비스 품질에 대한 선행연구를 통해 건강검진 경험가치의 유형별 평가요인을 도출한다. 둘째, 질적, 양적 서비스디자인방법론을 활용하여 수요자 중심 여정별 경험가치 품질 측정 결과 및 이해관계자인터뷰 등을 바탕으로 서비스디자인 아이디어를 구체화하고 건강 검진 서비스 블루프린트와 프로토타입을 제안한다. 마지막으로 서비스디자인의 평가를 위해 기대불일치 모형을 활용하여 제안된 서비스컨셉의 효과성을 검증하고 향후 건강검진 서비스 개선을 위한 서비스 디자인 전략을 제안한다. 본 연구는 i)건강검진 프로세스를 수요자 여정 중심으로 재구성하고 단계별 경험가치의 품질을 정성적, 정략적으로 측정하고 비교분석하였으며, ii)서비스디자인의 결과물의 효과성을 수요자 중심으로 검증하였다는 점에서 이론적, 실무적 시사점이 있다. 본 연구의 결과는 향후 국가건강검진 서비스 질 향상을 위한 기초자료로서 활용될 수 있을 것으로 사료된다. As awareness of the importance of health increases, the importance and interest of medical check ups continue to increase in Korea. Based on this trend, new medical check up centers have increased quantitatively with demand. Existing centers have invested only in appearance, making only superficial changes. However, improving the design of essential and fundamental customer-centered medical check up services is still insufficient. Therefore, the purpose of this study is to propose a customer-centered medical check up journey analysis, design development based on experience value, and it proposed an improved medical check up service design that has completed a verification process. This study consists of 3 phase. First, through advanced study on user experience value and quality of medical services, evaluation factors by type of medical check up experience value are derived. Second, using qualitative and quantitative service design methodologies, experience value quality evaluation and stakeholder interviews are conducted by consumer-centered journey. Based on this, it embodies the idea of service design and proposes a blue print and prototype of the medical check up service. Lastly, for evaluation of service design, we validated an effectiveness of the proposed service concept through the expectation disagreement model and propose a service design strategy for future medical check up service improvement. This study shows that i)The medical check up process was reorganized with consumer-centered view, and the quality of experience value by step was measured and analyzed qualitatively and quantitatively. ii) There are theoretical and practical implications in that the effectiveness of the results of the service design has been verified by consumers. The results of this study are expected to be used as a basic data for improving the quality of national medical check up services in the future.
식용식물자원으로부터 활성물질의 탐색-XI -GC를 이용한 상추(Lactuca sativa L.)의 품종별 Phytol 함량 분석-
송명종,이진희,방면호,김지영,정대균,배동근,김인호,백남인,Song, Myoung-Chong,Lee, Jin-Hee,Bang, Myun-Ho,Kim, Ji-Young,Chung, Dae-Kyun,Pai, Tong-Kun,Kim, In-Ho,Baek, Nam-In 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.4
An easy, sensitive and rapid method for the analysis of phytol, a strong ACAT (Acyl-CoA: Cholesterol Acyltransferase) inhibitory diterpenoid, was established. The pre-treatment of sample for GC analysis of phytol includes aq. MeOH extraction, partition of the extracts between EtOAc and water, and filtration of organic phase through Supelclean LC-Si SPE tube. The GC analysis of phytol for a variety of Lactuca sativa was carried out on DB-5 capillary column with flame ionization detector (FID). The consistency in phytol contents according to each variety was not shown. Especially, Jeoktoma, as RS-2 type, showed the highest phytol content.
LC-MS/MS를 이용한 채소류 및 서류의 클로로젠산 함량 조사
류지은(Ji-Eun Ryu),김운호(Woon-Ho Kim),배호정(Ho-Jeong Bae),정유정(You-Jung Jung),최영주(Young-Ju Choi),문경은(Kyeong-Eun Moon),최종철(Jong-Chul Choi),채경석(Kyung-Suk Chae),이진희(Jin-Hee Lee),도영숙(Young-Sook Do),최옥경(Ok-Kyung C 한국식품영양과학회 2020 한국식품영양과학회지 Vol.49 No.8
본 연구는 LC-MS/MS를 이용해 다소비 채소류 및 서류에 함유된 9종의 chlorogenic acid 이성질체를 분석하기 위하여 시료 추출 후 QuEChERS kit으로 정제하는 전처리법을 확립하였고, Syncronis C18 컬럼을 사용하여 30분 동안 분석하는 이동상 용매 조성과 9종의 이성질체의 정량 및 정성 이온을 선택하여 negative 모드에서 분석하는 기기 분석법을 확립하였다. 확립한 분석법은 AOAC 가이드라인에 따라 특이성, 직선성, 검출한계, 정량한계, 정확성, 정밀성을 확인하여 유효성을 검증하였다. 다소비 채소류 및 서류 43품목(48품종)의 chlorogenic acids 함량을 분석한 결과, 24품목(29품종)에 함유되었음을 확인하였다. 채소류의 경우 39품목(42품종) 중 22품목(25품종)에 chlorogenic acids가 함유되었으며(0.01±0.01~38.31±8.73 ㎎/100 g FW), 취나물, 케일, 미나리, 우엉, 상추, 브로콜리, 콜리플라워, 가지, 치커리, 도라지 순으로 함량이 높게 나타났다. 서류는 고구마(호박고구마, 밤고구마), 감자(로즈밸리, 수미), 마, 토란 등 4품목(6품종)을 분석하였는데, 고구마의 경우 밤고구마(1.31±0.52 ㎎/100 g FW)보다 호박고구마(1.42±0.39 ㎎/100 g FW)에, 감자의 경우 수미(0.09±0.03 ㎎/100 g FW)보다 로즈밸리(0.37±0.07 ㎎/100 g FW)에 chlorogenic acids 함량이 높게 나타났다. 또한 취나물, 미나리, 고구마, 감자를 대상으로 조리시간에 따른 chlorogenic acids 함량 변화를 확인한 결과, 취나물과 미나리는 30초 삶았을 때 가장 높은 함량을 나타내었고, 감자는 30분, 고구마는 20분쪘을 때 chlorogenic acids 함량이 높게 나타났다. 본 연구에서는 다소비 채소류 및 서류의 chlorogenic acids 함량과 조리시간에 따른 chlorogenic acids 함량 변화를 확인하여 식품 내 chlorogenic acids 함량에 관한 기초자료로 제공하고자 하였다. In this study, a sample preparation method and simultaneous determination method were developed to determine the chlorogenic acids content of frequently consumed vegetables, root and tuber crops in Korea by liquid chromatography coupled to mass spectrometry. The developed method was validated for its specificity, linearity, limit of detection, limit of quantification, recovery, accuracy, and precision based on the AOAC guidelines. Among the 39 items of vegetables, 22 items (0.01±0.01∼38.31±8.73 ㎎/100 g fresh weight (FW)) were quantified. The chlorogenic acids content of the vegetables was in the following order: chwinamul (38.31±8.73 ㎎/100 g FW), kale (22.93±0.75 ㎎/100 g FW), water dropwort (10.67±4.46 ㎎/100 g FW), burdock root (9.72±2.52 ㎎/100 g FW), red lettuce (leaf) (8.66±5.37 ㎎/100 g FW), broccoli (2.45±0.50 ㎎/100 g FW), and cauliflower (2.35±0.36 ㎎/100 g FW). Among the four items of root and tuber crops, sweet potato (1.42±0.39 ㎎/100 g FW) and potato (0.37±0.07 ㎎/100 g FW) were quantified. In addition, the chlorogenic acids content of chwinamul and water dropwort was highest when boiled for 30 seconds. Sweet potato steamed for 20 minutes and potato steamed for 30 minutes showed high chlorogenic acids contents.