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이중과제 훈련이 뇌졸중 환자의 균형 및 보행에 미치는 영향
정세라 ( Se Ra Jung ),원종임 ( Bhsc Jong Jm Won ) 한국전문물리치료학회 2014 한국전문물리치료학회지 Vol.21 No.2
The purpose of this study was to examine the effects of dual-task training (cognitive and exercise tasks) on the balance and gait performance of chronic stroke patients. Eighteen subjects with chronic stroke were divided equally into two groups, an experimental group and a control group. Subjects in both groups participated in an exercise program, performing the same tasks, for 45 minutes per day, three times per week for four weeks. The experimental group also performed additional cognitive task. The experimental group showed a more significant improvement than the control group on the Berg Balance Scale, the Timed Up and Go Test, the Korean Activities-Specific Balance Confidence Scale, and the Functional Gait Assessment (p<.05). The cognitive task error rates in the final week were significantly less than in the first week in the experimental group (p<.01). These results suggest that dual-task training for chronic stroke patients is effective in improving balance, gait, and cognitive abilities.
열적으로 안정한 금나노입자를 이용한 블록공중합체 내에서의 입자위치 조절
김세용(Se Yong Kim),유미상(Mi Sang Yoo),정세라(Se Ra Jung),백관열(Kwan Yeul Paek),김범준(Bum Joon J. Kim),방준하(Joon A Bang) 한국고분자학회 2011 폴리머 Vol.35 No.3
유기/무기 혼합 물질은 뛰어난 성능으로 인해 지난 수년간 다양한 분야에서 많은 관심을 받고 있다. 고분자 매트릭스에서의 무기 나노입자의 위치 및 분산을 조절하기 위해 싸이올(-SH) 기능기로 말단이 치환된 고분자 리간드가 나노입자의 표면 성질을 개질하는 데에 많이 사용되고 있다. 그러나 싸이올 기능기와 금속 나노입자간의 특정한 결합은 높은 온도에서는 매우 불안정하다. 본 연구진은 UV 경화가 가능한 azide 그룹을 고분자 리간드에 도입하여 열적으로 매우 안정한 금나노입자를 합성하여 보고한 바 있다. 본 연구에서는 더 나아가 표면 성질이 개질된 열적으로 안정한 금 나노입자를 얻기 위해서 상대적으로 극성인 UV 경화 가능한 azide와 무극성인 스티렌의 공급 몰 비를 각각 다르게 해서 다양한 UV 경화성 고분자 리간드를 합성하였다. 이를 이용해 합성한 금나노입자는 열적으로 매우 안정하였으며 PS-b-PMMA와 같은 블록공중합체 매트릭스 내에서 금나노입자의 위치를 한 도메인에서 계면으로 정교하게 조절 할 수 있음을 확인하였다. Organic/inorganic hybrid materials have a lot of interest in various areas due to their fascinating properties. To control the location and dispersion of inorganic nanoparticles within polymer matrix, thiol-terminated polymeric ligands have been widely used to tune the surface property of nanoparticles. However, the specific binding between the thiol functional group and metal is unstable with increasing temperature. To archive the thermally-stable Au nanoparticles, we previously synthesized various UV-crosslinkable polymeric ligands, which have different compositions of polar, UV-crosslinkable azide unit comparing to non-polar 스티렌 units. After crosslinking the Au nanoparticles, it was found that the nanoparticles had superb stability at high temperature (above 180 ℃). In this work, we used thermally-stable Au nano-particles to control the location within the polymer matrix. By changing the amount of polar azide units in the polymeric ligands, we could precisely control the location of nanoparticles from one domain to the interface of block copolymer templates.
복합 레진과 교합면 index를 활용한 치아 균열 증후군의 치료 : 증례보고
박태영(Tae-Young Park),조아라(A-Ra JO),이일화(Il-Hwa Lee),정세라(Se-Ra Jung),민정범(Jeong-Bum Min) 대한치과의사협회 2021 대한치과의사협회지 Vol.59 No.3
Objectives: Cracked Tooth Syndrome(CTS) refers to an incomplete fracture of a vital posterior tooth that involves the dentin and sometimes extends into the pulp. The composite resin restoration with cuspal coverage is less invasive treatment option and have many advantages for the management of CTS. This case report describes the treatment of cracked tooth with composite resin by cuspal coverage and 1-year follow up of maxillary second molar. The composite resin restoration with cuspal coverage was place over cracked tooth. During the direct restorative process, the use of clear occlusal index made filling very easy and fast. Also, it could be used immediately for the management of CTS. In conclusion, in cracked tooth without pulpitis, cusps covering with composite resin restoration can be used in the early stage, and may delay root canal treatment and restoration of crown.
지속성 외래 복막 투석 환자에서 C반응단백과 관상동맥 질환과 사망률
장상필,박정식,김유미,박종하,김순배,정세라,이준승,유지숙,홍창기 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.6
Background: Atherosclerotic vascular disease is major cause of morbidity and mortality in dialysis patients. C-reactive protein(CRP) as a marker of inflammation appears to be clinically useful in prediction of coronary heart disease and mortality. This study is designed to test whether plasma concentration of CRP correlates with coronary heart disease and mortality in CAPD patients. Methods: A total of l37 end-stage-renal disease patients undergoing CAPD were included. The measurement of baseline CRP and stress thallium SPECT were performed in all patients. Patients were followed prospectively from initiation of dialysis to June 1999 for analysis of survival rate and cause of death. Coronary angiography performed in 16 of 32 patients showed all positive results. Results: 32 patients showed positive results in thallium SPECT. The baseline CRP concentration were higher among patients with positive results in thallium SPECT than those with negative results(1.05g/L vs 1.30mg/dL, p$lt;0.001). The survival rate was significantly lower in lower CRP group than higher CRP group (44months vs 26 months, p$lt;0.001). However, There was no difference in cause of death according to serum CRP level. Death from cardiac cause is significantly higher among patients with positive thallium SPECT than negative results. The most common cause of death are, in descending order of frequency, cardiac disease including acute MI, sepsis, cerebrovascular disease. Conclusion: The baseline level of inflammation as assessed by the plasma concentration of CRP independently predicts the risk of coronary heart disease and survival in CAPD patients.
한국인 궤양성 대장염 환자의 진단시 임상적 특징과 진단 첫해의 예후
김진호,장우영,박종범,최재원,민영일,김해경,김영민,홍원선,명승재,양석균,정세라,정훈용 대한소화기학회 2000 대한소화기학회지 Vol.36 No.5
Background/Aims: This study was performed to investigate the clinical features of ulcerative colitis at diagnosis and to evaluate its clinical course and prognosis during the first year of diagnosis in Korean patients. Methods: Symptoms, disease extent and activity, and results of the treatment were retrospectively analyzed in 128 patients (male 61, female 67) diagnosed to have ulcerative colitis at the Asan Medical Center between June 1989 and September 1998. Results: At diagnosis, proctitis was noted in 41 cases (32.0%), and left-sided colitis and extensive colitis were noted in 44 (34.4%) and 43 (33.6%), respectively. Disease activity was mild in 54 patients (42.2%), moderate in 51 (39.8%), and severe in 23 (18.0%). All patients showed the remission rate of 96.1%, operation rate of 2.3%, and mortality rate of 0%. All the patients with mild activity showed remission. Of the patients with moderate activity, 96.0% showed remission, 2.0% had persistent symptoms for l year and 2.0% underwent operation. Among the patients with severe activity, 87.0% reached remission, 4.3% had persistent symptoms for 1 year and 8.7% underwent operation. The relapse rate during the first year of diagnosis was 24.4% (30/123) and there was no statistical significance between relapse rate and activity or extent of the disease at diagnosis. Conclusions: The short-term prognosis of ulcerative colitis in Korean patients is at least as good as that in Western countries.