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이경훈,최경신,이찬재,Lee, Gyeong-Hun,Choe, Gyeong-Sin,Lee, Chan-Jae 선박안전기술공단 2004 선박안전 Vol.15 No.-
어선전복사고의 원인을 분석하여 이러한 사고가 선체복원성, 예비부력, 방수구 및 잘못된 선체운용술과 어떠한 인과관계가 있는지를 판단하고 이에 대한 개선점을 도출코자 하였다.<중략>
강판으로 접합된 프리스트레스트 콘크리트보의 구조성능 평가를 위한 실험연구
이경훈,김점한,Lee. Kyoung-Hun,Kim. Jeom-Han 한국방재학회 2010 한국방재학회논문집 Vol.10 No.5
In this study, a monotonic loading test to estimate structural capacity of 12 meter long full scale precast pre-stressed concrete beam specimen was performed with a 2,000 kN dynamic actuator. A couple of embedded steel plate was installed at the ends of the beam and specimens were connected to steel girder frame with high tension bolts. Nominal compressive strength of pre-stressed concrete beam and slab were 50 MPa and 24 MPa respectively. Two HD25 tensile steel reinforcements were welded on vertical plate of embedded steel plate. Pre-stressed concrete beam specimen was loaded by displacement control method with a certain loading pattern which was repeated loading and unloading with 10mm increment displacement. About 88.34%, 86.97% and 66.83% of displacement restoration ratios were evaluated at elastic, inelastic and plastic behavior region of specimen respectively. 본 연구에서는 2,000 kN 용량의 actuator를 이용, 12 m 경간의 실물 크기로 제작된 프리스트레스트 콘크리트 보의 구조성능 평가를 위한 실험을 수행하였다. 보의 양 단에는 접합을 위한 강판을 매립하였으며 시험체는 별도로 제작된 철골 보에 고력볼트접합 방식으로 세팅되었다. 프리스트레스트 콘크리트와 슬래브 콘크리트의 설계기준강도는 각각 50 MPa와 24 MPa이며, 인장 철근으로 사용된 2-HD25 철근은 매립강판의 구성요소 중 하나인 수직강판에 용접하였다. 실험은 변위제어법에 의하여 수행되었으며 10 mm의 변위를 증가시키며 loading과 unloading을 반복적으로 가력하였다. 실험결과를 살펴보면, 탄성거동구간에서는 약 88.34%, 비탄성거동구간에서는 약 86.97% 그리고 소성거동구간에서는 약 66.83%의 프리스트레싱에 의한 변위복원능력을 나타냄을 알 수 있었다.
정신분열병 환자에서 Clozapine과 그 대사물들의 혈장농도 및 FMO3 유전자 변이
이경훈,김철응,Lee, Kyung-Hoon,Kim, Chul Eung 대한생물정신의학회 2006 생물정신의학 Vol.13 No.3
Objective : The relationship between the total daily dose of clozapine given and the plasma concentrations of clozapine and its metabolites(N-desmethylclozapine and clozapine N-oxide) and the effect of Glu158Lys (wild-type : Glu, 'H' ; variant : Lys, 'h') and Glu308Gly(wild-type : Glu, 'D' ; variant : Lys, 'd') variation in FMO3 gene on plasma concentrations of clozapine and its metabolites was studied in schizophrenic patients. Methods : Trough plasma concentrations of clozapine and its metabolites were measured in 34 schizophrenic patients receiving clozapine. The genetic variation of 'h' and 'd' in FMO3 were analyzed in 21 among 34 patients. Results : A linear relationship between the total daily dose of clozapine given(mg/kg body weight per day) and the plasma concentrations(nM) of clozapine was revealed by regression analysis(p<0.001) in the 23 patients receiving a constant daily dose of clozapine for 8 days. The plasma molar concentration ratios of clozapine N-oxide/clozapine in 8 subjects with 'hh' or 'Hh' alleles were not different from those in 6 subjects with 'HH' alleles and the plasma molar concentration ratios in 6 subjects with 'dd' or 'Dd' alleles were not different from those in 8 subjects with 'DD' alleles. Conclusion : The effect of Glu158Lys and Glu308Gly variation in FMO3 gene on clozapine metabolism could not be shown.
The Adsorption of Methanethiol and Benzenethiol on Silver Surfaces
이경훈,박상현,김호징,Lee, Gyeong Hun,Park, Sang Hyeon,Kim, Ho Jing Korean Chemical Society 1995 Bulletin of the Korean Chemical Society Vol.16 No.2
The adsorption of methanethiol and benzenethiol on Ag(111) and Ag(100) surfaces is studied respectively, employing ASED (Atom Superposition and Electron Delocalization) method. Metal surfaces are modelled by 3-layer clusters. The corresponding thiolate anions are taken as adsorbates. The highly coordinated binding sites are most favored for both surfaces. The tilted angles of C-S axis from the surface normal are nearly zero. There's Charge transfer from adsorbate to substrate and the stretching frequency of C-S bond upon adsorption is blue-shifted from its gas phase counterpart, and its amount is the smallest at most highly coordinated site. FMO (Fragment Molecular Orbital) analysis of the system give the explanation for these results.