폐 과오종의 세침흡인 세포학적 소견 - 2예 보고 -

김진아,김영실,이안희,심상인,김병기,김경미,Kim, Jean-A,Kim, Young-Sill,Lee, An-Hi,Shim, Sang-In,Kim, Byung-Kee,Kim, Kyoung-Mee 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.1

Pulmonary hamartoma is an uncommon benign tumor consisting of a mixture of loose fibromyxoid tissue, cartilage, fat, and cleft-like spaces lined by cuboidal or ciliated epithelium. Cytologically, the presence of a mesenchymal component is essential for the diagnosis of pulmonary hamartoma. We report the fine needle aspiration cytologic findings of two cases of pulmonary hamartoma. Case 1 was a 71-year-old woman with a mass, measuring $1.8{\times}1.5cm$ in the upper lobe of the right lung. Case 2 was a 51-year-old woman with a mass, measuring $2.3{\times}2.0cm$ in the lower lobe of the right lung. Fine needle aspiration cytology of both pulmonary masses revealed several sheets of loose fibromyxoid tissue fragments with focal cartilaginous differentiation and a few clusters of bland cuboidal epithelial cells on the bloody background. The diagnosis was histologically confirmed by needle biopsy.

비전형적인 세침흡인 세포학적 소견을 보인 후복막강 부신경절종 - 1례 보고 -

김진아,김영신,강창석,이안희,김병기,심상인,김선무,Kim, Jean-A,Kim, Young-Shin,Kang, Chang-Suk,Lee, An-Hi,Kim, Byung-Kee,Shim, Sang-In,Kim, Sun-Moo 대한세포병리학회 1994 대한세포병리학회지 Vol.5 No.1

A case of retroperitoneal paraganglioma is presented with fine needle aspiration cytologic features. A 57-year-old woman complained of abdominal discomfort and left flank pain for 2 years. The abdominal CT scan revealed an ovoid mass left to the abdominal aorta. Percutaneous fine needle aspiration was performed from the mass. The smear revealed cellular sheets or groups on hemorrhagic background. The tumor cells were ovoid, round to spindle shaped with mild to moderate cellular pleomorphism. The nuclei were round to ovoid and had evenly dispersed chromatin and small nucleoli. The cytoplasm was amphophilic, finely granular and poorly defined. Cells having large or spindle nuclei were quite frequently observed, however, mitosis was not present The cytologic findings suggested paraganglioma, but the frequent spindle cell pattern and the pleomorphism made it difficult to exclude other endocrine tumors and sarcomas. The clinical, histological and ultrastructural findings as well as cytologic findings contributed to confirmatory diagnosis.

포스터 발표 - 생물공학분과 / 펄프 , 제지 , 피혁분과 / 유지 , 계면활성제분과 / 접착제 , 도료 잉크분과 / 정밀화학분과 : 축산폐수중 암모니아성 질소의 MAP 결정을 통한 제거 - 결정생성 반응과 침전제거조작의 최적조건 모색

김진아,김연옥,김종수,이희찬 ( J . A . Kim,Y . O . Kim,J . S . Kim,H . C . Lee ) 한국공업화학회 1997 한국공업화학회 연구논문 초록집 Vol.1990 No.3

뺨 점막에 발생한 충실성 선양낭성암종의 세침흡인 세포학적 소견 - 1예 보고 -

김진아,김영실,이안희,심상인,김병기,김경미,Kim, Jean-A,Kim, Young-Sill,Lee, An-Hi,Shim, Sang-In,Kim, Byung-Kee,Kim, Kyoung-Mee 대한세포병리학회 2000 대한세포병리학회지 Vol.11 No.2

Adenoid cystic carcinoma constitutes 4 percent of ail benign and malignant epithelial salivary gland tumors and is a highly malignant tumor of the salivary glands. The cytologic presentation in aspirates is usually characteristic with spherical clusters(balls) of small tumor cells filled with hyaline material. But in case of the poorly differentiated variety(solid type), it is difficult to differentiate from other tumors because sheets of small, fairly monotonous malignant cells, with somewhat larger and more conspicuous nuclei are only seen. The cytologic findings of fine needle aspiration of solid type adenoid cystic carcinoma of buccal mucosa in a 51-year-old man are presented. On cytologic findings, solid sheets of monotonous tumor cells with focal necrosis was noted on a hemorrhagic background and the characteristic cytologic features of adenoid cystic carcinoma was absent.

축산폐수중 암모니아성 질소의 MAP 결정을 통한 제거 - 결정생성 반응과 침전제거조작의 최적조건 모색

김진아,김연옥,김종수,이희찬 ( J . A . Kim,Y . O . Kim,J . S . Kim,H . C . Lee ) 한국공업화학회 1997 한국공업화학회 연구논문 초록집 Vol.1997 No.0

브린졸라미드 복합제의 개방각 녹내장 또는 고안압증에 대한 효과 및 안전성 검증: 체계적 문헌 고찰 및 메타분석 연구

김진아,이희영,Kim, Jin A,Lee, Heeyoung 한국임상약학회 2021 한국임상약학회지 Vol.31 No.3

Background: The treatment of primary open-angle glaucoma (POAG) or ocular hypertension (OHT) for intraocular pressure (IOP) reduction is recommended to proceed with the use of the compound. Therefore, this study aimed to evaluate the efficacy and safety of brinzolamide combination therapy on POAG and OHT following the subgroup analysis among types of brinzolamide combined medications. Methods: By June 2019, PubMed, EMBASE and Cochrane Library were searched to find a study that met our inclusion criteria. Based on randomized control trials (RCTs), we collected studies that tested the brinzolamide combination therapy in POAG and OHT patients, and analyzed the literature identified by the results of the study on IOP reduction and adverse reactions. Results: A total of 13 literature was collected to conduct an analysis including 2,197 patients. The intervention included brinzolamide combination therapies, combined with timolol, brimonidine, PGA or combined with both brimonidine and PGA. The analysis showed significant decreasing tendency for values at morning and end treatment per day in the use of brinzolamide combination therapy in the absolute IOP change (mean difference (MD) -1.41; 95% CI -1.92, -0.90; p<0.001 vs. MD -1.46; 95% CI -2.03, -0.89; p<0.00001, respectively). We could see higher adverse reactions in the brinzolamide combination group using intervention (odds ratio 1.43; 95% CI 1.20, 1.71; p<0.0001). Conclusion: Regarding IOP reduction in POAG and OHT patients, brinzolamide combination therapy is more effective but less safe than control treatment, which diverse among types of combined medications. Thus, more individualized therapy should be applied in real-world practice.

배추 속 작물의 개화형 판별 마커 시스템 개발

김진아,김정선,홍준기,이연희,이수인,정미정,Kim, Jin A,Kim, Jung Sun,Hong, Joon Ki,Lee, Yeon-Hee,Lee, Soo In,Jeong, Mi-Jeong 한국식물생명공학회 2017 식물생명공학회지 Vol.44 No.4

개화는 배추종 작물의 생산성과 연관된 중요 발달 특성 중 하나이다. 이식 후, 갑작스러운 저온에 노출되어 때이른 개화를 하게 되면 수확되는 생산물의 양과 질이 떨어지게 된다. 따라서, 개화조절 메커니즘을 이해하는 것은 배추 종 작물의 농업적 생산성을 향상시키는데 도움을 줄 것이다. 춘화는 배추과 작물에서 일반적으로 알려져 있는 개화를 유도하는 중요한 요소이다. 그러나 옐로우 사순이나 코마수나와 같은 배추 아종은 춘화처리 없이도 개화한다. 1일을 주기로 하여 생물의 생리기작을 조절하는 생체시계 유전자는 일장감응형의 개화 조절에 중요한 역할을 하지만 춘화처리를 통해 개화를 유도하는 기작과도 연관되어 있다. 본 논문에서는 22개의 배추 아종을 개화에 춘화처리가 필요한 춘화형과 춘화처리 없이도 개화하는 비춘화형으로 나누어 보존된 생체시계 유전자, BrPRR1 군의 염기서열 분석을 수행하였다. 그 중 BrPRR1b 유전자의 결손 영역으로 춘화형과 비춘화형 두 그룹을 구분할 수 있었다. 이 서열변이를 증폭할 수 있는 PCR 프라이머를 디자인하여 비춘화형 배추 아종에서는 451 bp의 긴밴드를, 춘화형 배추에서는 422 bp의 작은 크기의 밴드를 증폭할 수 있었다. 이 프라이머 세트는 43개 배추 아종과 4개의 배추속 작물, 브로콜리, 양배추, 갓, 그리고 유채의 개화형을 구분하는데 적용되었다. 각 작물의 PCR 결과와 개화시기에 대한 정보를 통하여 프라이머 세트가 개화형을 판별할 수 있는 마커로 이용될 수 있음이 확인되었다. 이 마커시스템은 배추 종 작물 육종에 유묘 단계에서 개화형을 판단하는데 이용할 수 을 것이다. 또한 이 결과들은 생체시계 유전자가 배추 종 작물의 개화를 조절하는 좋은 전략이 될 수 있음을 보여주었다. Flowering is one of the most important development traits related to the production of Brassica rapa crops. After planting, a sudden low temperature triggers premature flowering, which leads to a reduction in the yield and quality of harvested production. Therefore, understanding the mechanism of flowering control is important in the agricultural productivity for preventing Brassica rapa crops. Vernalization is generally known as the main factor of flowering in the Brassica plant. However, in the subspecies of Brassica rapa, some accession such as Yellow sarson and Komatsuna display the flowering phenotype without vernalization. Circadian genes, which diurnally regulate plant physiology, have a role for photoperiodic flowering but are related to the regulation of the vernalizarion mechanism. In this report, the 22 B. rapa accession were divided into two groups, vernalization and non-vernalization, and the sequenced circadian gene, BrPRR1s. Among them, the BrPRR1b gene was found to have deletion regions, which could classify the two groups. The PCR primer was designed to amplify a short band of 422bp in the vernalization type and a long band of 451bp in the non-vernalization type. This primer set was applied to distinguish the flowering types in the 43 B. rapa accession and 4 Brassica genus crop, Broccoli, cabbage, mustard, and rape. The PCR analysis results and flowering time information of each crop demonstrated that the primer set can be used as marker to discern the flowering type in Brassica crops. This marker system can be applied to the B. rapa breeding when selecting the flowering character of new progenies or introducing varieties at an early stage. In addition, these results displayed that the circadian clock genes can be a good strategy for the flowering control of B. rapa crops.

미국 문화, 그 기로에 서서 - NEA(국립예술진흥기금)를 둘러싼 논쟁 중심으로

김진아,Kim, Jin-A 한국미술이론학회 2006 미술이론과 현장 Vol.4 No.-

'문화 전쟁(Culture Wars)'은 1980년대 말부터 1990년대 초 미국에서 보수주의자와 진보주의자 사이에 벌어진 문화적 논쟁을 일컫는다. 이 용어는 제임스 헌터(James Hunter)의 책 "문화 전쟁: 미국을 정의하려는 노력(Culture Wars: The Struggle to Define America)"의 출간으로 대중화되었고, 당시 공화당 대통령 후보였던 패트릭 부캐넌(Patrick Buchanan)에 의해 급부상하게 된다. 그는 "이 나라에는 지금 종교 전쟁, 즉 냉전만큼 중요한 '문화 전쟁'이 일어나고 있고, 이것은 미국의 영혼을 위한 전쟁이다." 라고 부르짖으며 급변하는 문화 정체성의 위기 속에서 미국적인 전통을 지키고자 하였다. 이 문화 전쟁은 여러 다양한 논쟁을 함의하고 있었는데, 교목제도의 폐지, 교육기관에서의 다문화주의(multiculturalism) 커리큘럼 도입, 동성애자의 군복무, 낙태, 총기 소지 등의 허용 문제로 당시 미국의 교육계, 문화계뿐만 아니라 정치계, 입법부에서도 첨예한 대립 구도를 형성하였다. 미술계에서 가장 치열했던 문화 전쟁은 안드레 세라노(Andres Serrano)의 작품전과 ${\ll}$로버트 메플소프: 완벽한 순간(Robert Mapplethorpe: The Perfect Moment)전${\gg}$이 공공기금인 국립예술진흥기금(National Endowments for the Arts, NEA)의 지원을 받아 개최되는 것이 타당한 것이냐에 대한 논쟁에서 표출되었다. 이 두 전시를 기점으로 그 뒤로도 여러 미술 전시회와 음악회, 연극 등을 둘러싼 NEA 기금 지원과 관련한 분쟁은 한동안 계속된다. 이 글은 이러한 미술계 문화 전쟁의 발전 과정과 몇몇 논점에 초점을 맞추되, 세라노나 메플소프의 작품 자체를 분석하고 비평하는 글이 아님을 밝혀 둔다. 본 연구는 분쟁의 전개에 대한 상세한 기술적, 연대기적 조사보다는 그 발단과 전개 과정에서 몇 가지 핵심적인 사항들을 기술하고, 이 사항들이 암시하는 정치적, 미학적, 미술사적 시각의 충돌에 대해 지적하는 글이 될 것이다. 더 나아가 당시 이러한 논쟁이 미국 미술계에 의미하던 것, 미국 문화 전체에 의미하던 것은 과연 무엇인가에 대한 비평적 질문으로 글을 맺고자 한다. The cultural debates between conservatives and liberals at the end of the 1980s and in the early 1990s were termed as "culture wars." The "culture wars" involved a diverse range of controversial issues, such as the introduction of multicultural curricula in educational institutions, prayers in schools, whether to allow gays to serve openly in the military, and whether abortion should be permitted. The most heated debates of the "culture wars" regarding art raged over the NEA and the question of whether Andres Serrano's works should have been publicly funded, in addition to the exhibition "Robert Mapplethorpe: The Perfect Moment" which were charged as projecting "obscene" or "blasphemous" images. This paper examines the development of culture wars in art and focuses on several issues invoked by the NEA debates. However, it is not a detailed chronological investigation. Rather it pays attention to the several phases of the debates, analyzing and criticizing the clashes of the political and esthetical points of views between conservatives and liberals. How could NEA funding, a mere fraction of the federal budget, have become so critical for both sides(conservative and liberal), for politicians and artists' groups, and for academics and the general public? The art community was astounded by this chain of events; artists personally reviled, exhibitions withdrawn and under attack, the NEA budget threatened, all because of a few images. For conservative politicians, the NEA debate was not only a battle over the public funding of art, but a war over a larger social agenda, a war for "American values and cultures"based on the family, Christianity, the English language, and patriarchy. Conservative politicians argued the question was not one of "censorship" but of "sponsorship," since the NEA charter committed it to "helping museums better serve the citizens of the United States."Liberals and art communities argued that the attempt to restrict NEA funding violated the First Amendment rights of artists, namely "free speeches." "No matter how divided individuals are on matters of taste," Arthur C. Danto wrote, "freedom is in the interest of every citizen." The interesting phase is that both sides are actually borrowing one another's point of view when they are accompanied by art criticism. Kramer, representative of conservative art critic, objected the invasion of political contents or values in art, and struggled to keep art's own realm by promoting pure aesthetic values such as quality and beauty. But, when he talked about Mapplethorpe's works, he advocated political and ethical values. By contrast, art experts who argued for Mapplethorpe's works in the Cincinnati trial defended his work, ironically by ignoring its manifest sexual metaphor or content although they believed that the issues of AIDS and homosexuality in his work were to be freely expressed in the art form. They adopted a formalistic approach, for example, by comparing a child nude with putti, a traditional child-angel icon. For a while, NEA debates made art institutions, whether consciously or unconsciously, exert self-censorship, yet at the same time they were also producing positive aspects. To the majority of people, art was still regarded as belonging to the pure aesthetic realm away from political, economical, and social ones. These debates, however, were expanding the very perspective on the notion of what is art and of how art is produced, raising questions on art appreciation, representation, and power. The interesting fact remains: had the works not been swiped in NEA debates, could the Serrano's or Mapplethorpe's images gain the extent of power and acceptance that it has today?

사례분석을 통한 『상한론(傷寒論)』 변병진단체계(辨病診斷體系)의 서사의학적 가치의 탐색

김진아,이성준,Kim, Jin-A,Lee, Sung-Jun 대한상한금궤의학회 2014 대한상한금궤의학회지 Vol.6 No.1

Objective : The purpose of this study is exploring value of Shanghanlun six diagnostic system as Narrative Medicine by analyzing cases. Methods : In the article, we examined the theory of narrative medicine and current studies. And then key elements of narrative medicine was defined. On the basis of these, two medical cases were analyzed by reordering in accordance with time sequences and causality for confirming narrative factors. Results : The narrative approach to analyzing cases shows us that different diseases could be the result of same pathological patterns based on Shanghanlun. This tells us following four aspects. [1] Shanghanlun is the causes-oriented records and the text includes narrative factors. [2] Shanghanlun six diagnostic system is a process of constructing plot of medical case history through the clinical interpretation of contextual meaning of patient's life. [3] In the process of diagnosis, Schemata and script are engaged in assuming and confirming six patterns diseases. [4] The subjective factors of an individual can be applied universally through the provision of Shanghanlun. Conclusions : Narrative factors of Shanghanlun six diagnostic system suggest the possibility and value of Shanghan Medicine as Narrative Medicine in terms of Medical Humanities, essence of medical diagnosis and therapeutic action.

딥러닝 기반 병원네트워크 이상행위 탐지 시스템에 관한 연구

김강현(Kim Kang Hyun),정성수(Jung Sung Soo),한현욱(Han Hyun Wook) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.11