수지상세포에 대한 Callophyllis japonica 추출물의 면역조절효과

김미형,주홍구,Kim, Mi-Hyoung,Joo, Hong-Gu 대한면역학회 2007 Immune Network Vol.7 No.2

Background: A red seaweed, Callophyllis japonica has been traditionally eaten in the oriental area. In a recent study, it has been demonstrated that the ethanol extract of C. japonica have antioxidant activity. However, there are few studies about the effects of C. japonica on the function of immune cells. We investigated the immunomodulatory effects of C. japonica on the function of dendritic cells, the potent antigen-presenting cells. Methods: Bone marrow-derived dendritic cells (DCs) were used and the viability was measured by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay and trypan blue exclusion test. Cytokine and nitric oxide (NO) levels were determined by using ELISA and Griess reagent, respectively. The expression levels of DC surface markers were measured by flow cytometric analysis. Results: C. japonica ethanol extract did not significantly affect the DCs viability and the IL-12 production from DCs, irrespective of the presence of lipopolysaccharide (LPS). In addition, it did not significantly change the expression of DC surface markers. However, C. japonica ethanol extract significantly inhibited the LPS-induced NO production and also increased the proliferation of allogeneic lymphocytes activated by DCs. Conclusion: Our data suggests that C. japonica ethanol extract enhances the proliferation of allogeneic lymphocytes activated by DCs which is associated with inhibition of NO production from DCs induced by LPS.

가축매몰지 조성비용 평가

김미형,김건하,Kim, Mihyung,Kim, Geonha 한국지하수토양환경학회 2013 지하수토양환경 Vol.18 No.1

A lot of burial sites for the disposal of the contagious livestock slaughtered by foot and mouth disease were constructed in a short time for preventing the rapid spread of the virus. More than 4,700 carcass burial sites were constructed in 2011. Approximately 7 million poultry and 3.5 million livestock including head of cattle and swine were buried in farm land. However, the available cost data for a burial site was not provided. This study was to performed in order to understand the economic issues related to carcass burial disposal. The data from a local government was analyzed and the assumption data web based was constructed to evaluate the cost for constructing a carcass burial. The results showed that the local government paid KRW 5,386 for the burial disposal of a mortality (swine). It was estimated that the cost could be reduced through an appropriate measures.

단일 기관에서의 기존 갑상선 수술과 무기하 및 가스주입 전흉부접근 내시경 갑상선절제술의 임상적 고찰

김미형(Mi-hyeong Kim),김태원(Tae-won Kim),김기환(Kee-hwan Kim),안창혁(Chang-hyeok An),배자성(Ja-sung Bae),박우찬(Woo-chan Park),김정수(Jeong-soo Kim) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.79 No.6

Purpose: After the first endoscopic thyroidectomy by Huscher in 1997, several surgeons reported their experiences with endoscopic thyroidectomies. And these papers showed that clinical outcomes of endoscopic thyroidectomy are similar to conventional thyroidectomy. But, there was no randomized prospective trial to determine which approach of endoscopic thyroidectomy achieved better results. We evaluated clinical data of gasless and gas insufflation endoscopic thyroidectomies with conventional thyroidectomy to define its advantages or disadvantages. Methods: Between 1999 and 2009, 1,117 patients underwent thyroidectomies (1,149 cases). 747 cases was performed by conventional open method, 402 cases by endoscopic thyroidectomy. Among them, 317 cases were operated by gasless techniques and 85 cases by carbon dioxide gas insufflation. Results: Between conventional and endoscopic thyroidectomy groups, operation time, hospitalization period, tumor size, and number of retrieved lymph nodes were similar (P-value >0.05). Among 441 thyroid cancer patients, 19 had recurrence, of which 15/301 (4.98%) had conventional thyroidectomy, and 4/140 (2.85%) had endoscopic thyroidectomy. After postoperative radioactive iodine therapy, follow-up Tg levels were checked in 274 patients, the levels were <2.0 ng/㎖ in 87.63% (163/186) of patients after conventional thyroidectomies and in 93.18 % (82/88) following endoscopic thyroidectomies. There were no significant differences (P-value=0.58). Complication incidences (hypocalcemia, hoarseness, bleeding, wound infection) in both groups were not significantly distinctive (P-value=0.58). Conclusion: Minimally invasive techniques are generally applied even for malignancy in selected cases because of its advantages, such as cosmetic results. Through this study, we showed similar clinical outcomes of conventional and gasless or gas insufflations endoscopic thyroidectomy.

고정성 치열교정장치 장착환자에서 전문적 구강위생관리가 구강위생에 미치는 효과에 관한 연구

김미형(Mi Hyung Kim),김병옥(Byung Ok Kim) 조선대학교 구강생물학연구소 1994 Oral Biology Research (Oral Biol Res) Vol.18 No.1

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우선순위를 고려한 ATM 교환 제어기의 신경회로망 설계

김미형(Mi-Hyoung Kim),김장호(Jang-Ho Kim),박정한(Jeong-Han Park),김미선(Mi-Sun Kim),이동섭(Dong-Sub Lee),이주영(Ju-Young Lee),박창옥(Chang-Wouk Park),김영우(Young-Oo Kim),임인칠(In-Chil Lim) 대한전자공학회 1993 대한전자공학회 학술대회 Vol.1993 No.11

영양지원팀의 임상적 적용 방법

김은영 ( Eun Young Kim ),김주미 ( Ju Mee Kim ),김미형 ( Mi Hyung Kim ),권택수 ( Taek Su Kwon ),이혜승 ( Hye Seung Lee ),목희정 ( Hee Jung Mok ),홍정임 ( Jeong Im Hong ),김혜진 ( Hye Jin Kim ),김현경 ( Hyun Kyung Kim ),정성진 ( Sun 한국정맥경장영양학회 2013 한국정맥경장영양학회지 Vol.5 No.3

Purpose: Most hospitals have been reply to the consultation if the needed departments consult with the Nutritional Support Team (NST) for patient evaluation and management. However, as a common occurrence, some people requiring treatment cannot receive care due to lack of cognition of nutritional support and lack of resources for assessment of nutritional status. Methods: We provide an indication for screening of patients and for active nutritional support. Indications include symptoms that reflect the conditions of increasing nutritional requirement and decreasing nutritional supply. Two surgical wards and surgical intensive care unit were included and nursing teams recommended patients to the NST by interviewing inpatients if they met the indications. Results: We included 60 patients referred to the NST before applying for screening, from January 2005 to January 2009 and 44 patients selected for only five months by the NST after applying for screening. The number of consultations showed a slow decrease, 27 in 2005, 23 in 2006 to 10 in 2007, before applying for screening, but increased significantly to 44 for only five months after applying for screening. While the number of departments applying to the NST was five departments in 2005, six departments in 2006, and two departments in 2007, it increased significantly to eight departments. After applying for screening, the most common cause was ‘artificial nutrition longer than five days’ in 48.1%; the second cause was ‘poor nutrition status’ in 13.5%, and the third was ‘significant weight loss’ or ‘gastrointestinal function change’ in 8%. Moderate risk patients showed improvement and shifted to minor risk patients and normal patients. The rate of improvement was approximately 47.7%. Conclusion: The screening tools should be simple, as well as easy to use. Therefore, using this tool, we must actively select patients with poor nutrition and apply the screening tools rapidly. (J Korean Soc Parenter Enter Nutr 2013;5(3):117-121)

식물조직배양 기술을 이용한 새로운 실내 원예 장식품인 비보리움(Vivorium)의 개발

황민희(Min Hee Hwang),김도연(Do Yeon Kim),조인선(In Sun Cho),김미형(Mi Hyung Kim),권현숙(Hyun Sook Kwon),김종보(Jong Bo Kim),김수정(Su Jung Kim),김선형(Sun Hyung Kim) 한국식물생명공학회 2021 JOURNAL OF PLANT BIOTECHNOLOGY Vol.48 No.3

Indoor gardening includes wall greening, terrariums, and flower arrangements. Among these types of indoor gardens, the terrarium is easy to access for the general public, but in Korea, because of the focus on esthetics, the original purpose of creating terrariums, which was to grow plants sustainably in an enclosed space, has been lost. In addition, miniaturization of plants is required to grow plants in an enclosed space. Since the available plant species suitable for a terrarium are limited, only plants such as succulents, cacti, and moss have been used. In this study, Bronze (X Graptosedum) was used, and these problems were solved using the following three methods: placement and growth of virusfree plants in the terrarium; extending the diversity of plants with minimal size that can be planted in terrariums; and reducing the price of in vitro plants with minimal size by achieving large-scale production. In particular, tissue-cultured succulents were developed into a Vivorium by replacing the tissue culture container and renewing the composition of the plant. This paper suggests a new indoor horticultural field, Vivorium, that can improve the current limitations of terrariums and make them more accessible to the general public. The introduction and popularization of new indoor gardening fields with the increase in single-person households and indoor activities in the Pandemic era can also improve psychological stability among people and in the society.

국어 대명사의 어휘사

김미형(Mi Hyoung Kim) 한국어의미학회 2001 한국어 의미학 Vol.9 No.-

The purpose of this study is to examine the diachronic change of Korean pronouns. The study surveys the developmental aspects of Korean pronouns from the ancient language to the modern language. It also analyzes some characteristics of each personal pronoun, reflexive pronoun and infinite pronoun. There has been some diachronic change in Korean pronouns. This change has resulted from efforts to indicate the speakers, the listener and the referred object precisely, as well as the relationship between them.

충청남도 공무원의 순화 대상어 사용 실태 연구

김미형(Kim, Mi-hyoung),서은아(Seo, Eun-a) 우리말글학회 2014 우리말 글 Vol.61 No.-

이 연구는 충청남도 공무원의 행정 용어 사용 실태를 점검하는 한편 일반 국민을 대상으로 행정 용어에 대한 이해도·선호도 및 인지도 조사를 통해 행정 용어의 문제점을 진단하는 것이 목적이다. 행정 용어에 대한 이해도ㆍ선호도 조사에서는 ‘동법, SOC, 태스크포스, 동법’ 등의 정확한 뜻을 알고 있는지 살펴보았다. ‘SOC’는 85.1%의 국민이 정확한 뜻을 모른다고 대답했고, ‘태스트포스’는 79%, ‘동법’은 55.6%의 국민이 정확한 뜻을 모른다고 대답했다. 공문서에서 어려운 행정 용어를 사용하는 것에 대해서는 82.9%가 “좋지 않다.”라고 응답했고, 쉬운 행정 용어를 사용하는 것에 대해서는 52.8%가 “좋다.”라고 응답했다. 충청남도 공무원들이 쉬운 행정 용어를 얼마나 사용하는지, 문화체육관광부가 선정한 312개 행정 용어 순화 대상어의 사용 실태를 분석한 결과, 270개의 행정 용어가 사용되었으며 ‘파일’, ‘동법’, ‘투어’, ‘소요’, ‘유관기관’, ‘이벤트’ 등의 사용 빈도가 높게 나타났다. This study aims to examine the usage of refining target words by civil servants of Chungcheongnam-do, and to diagnose problems caused by those terms through an investigation of public understanding, preferences, and awareness of the administrative terms and related problems, in order to lay the foundation for improvement. For the investigation of the public understanding, preferences, and awareness of administrative terms, the expressions such as ‘dongbeop (same law), SOC, Mecca, landmark, task force, roadmap, fam tour and voucher’ were selected to find out whether the general public know their exact meaning. As a result, 85.1% of the respondents answered they did not know the exact meaning of ‘SOC’, and 79% answered the same for ‘task force’, 55.6% for ‘dongbeop’, 53.6% for ‘fam tour’ and 53% for the term ‘voucher’. In contrast, 53.7% of the people answered they roughly knew the meaning of ‘landmark’, and 46% said the same for ‘roadmap’, and 58% of the respondents said they knew exactly what ‘Mecca’ meant. When asked about the usage of administrative terms originated from Chinese characters and foreign words in official documents, 82.9% of the respondents answered it was “not good”, and for reasons behind it, 54.7% said “Hangeul alone is enough to convey meaning”. When asked about official documents with expressions that are easy to understand without difficult administrative terms, 52.8% of the respondents said “good”. People"s preference for the use of simple and easy expressions instead of challenging administrative terms, was explained by the reason picked by 72.1% of the respondents, which was “because it is easy to understand the meaning of the word”. In order to find out the frequency of refining words for official administrative terms used by the civil servants of Chungcheongnam-do, an analysis was conducted on the usage of 312 refining words selected by the Ministry of Culture, Sports and Tourism. And as a result, 270 of them were used and the total frequency turned out to be 327,175. And the word with the highest frequency turned out to be ‘file’ which was used 32,251 times, followed by ‘dongbeop’ with 24,099 times, ‘tour’ with 20.945 times, ‘soyo(required)’ with 15,615 times, ‘relative institution’ with 14,323 times and ‘event’ with 12,431 times in sequence. Among the refining words for administrative terms, there were some that have not been used at all, whereas, in certain cases, other refining words have been used much more frequently than the target terms to be refined. Therefore, it would be more effective to put continuous efforts to refine administrative terms rather than to impose regulative actions to make people “use refining words whenever possible” through official notices by the Ministry of Culture, Sports and Tourism as in current situation.

상명대학교 교양교육과정 전략과 그 특성

김미형(Kim, Mee Hyung) 성신여자대학교 교육문제연구소 2002 교육연구 Vol.36 No.-

본 논문에서는 상명대학교 교양교육과정의 전략과 특성에 관한 것이다. 대학의 교육은 전공교육과 교양교육으로 이루어지는데, 이 중 전공교육도 본 대회의 주제인 벤처 의식 관련성을 긴밀하게 가지고 있지만 여기서는 대학생 모두에게 고루 적용되는 교양교육의 문제와 벤처 의식과의 연계성 문제를 생각해 보고자 한다. The purpose of this review is to introduce the cultural course and cultural program of Sangmyung university. The cultural course is a regular curriculum, being composed of various effective subjects. The characters of this course are a professional operation system and a system of core educational course. Especially, core educational course system is able to make sure each subject's special purpose which is essential to fill up the demands of the present age. To realize an educational effect, every professors in charge of the courses must develop the substance fitting to increase student's creative mind and challengeable spirit. Extra cultural program of Sangmyung university is the business on specialization of the local culture. There are various business, establishing the cultural core center, researching the cultural topics, playing the active cultural performance and exhibition, constructing the database in network system. In the course of all business, students can experience a creative mind and challengeable spirit.