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      • Characterization of cricket song patterns and the behavior observation of Teleogryllus emma (Orthoptera:Grylloidea)

        Ji Chang Woo,Kim Nam-Jung,Lee Sang-Guei,Hwang-Yong Kim,Choi Hoon-Sik,Song In-Sun,Ko Jee Sun 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.05

        We analyzed the chirp sound and behavior of Teleogryllus emma with observation system, which was consisted of computer, ccd-camera and microphone. Computational methods of wavelet transformation and Self-Organizing Maps (SOM) were utilized to characterized the chirp sound of insect species for automatic counting in this study. Wavelets were initially applied to feature extraction of the chirp sound. Wavelet coefficients were accordingly calculated based on the basis function (e.g., Morlet). The obtained coefficients were subsequently provided to count number of chirps in each song. Sound structure of insect specimens consisted with long chirp and short chirp and the patterns of song were grouped by frequency of long chirp and short chirp. The song patterns of insect specimens were divided by Self-Organizing Map (SOM) that was used number of chirp as input data. Application of computational methods to automatic detection of chirp sound was further discussed for obtaining objective assessment in behavior science.

      • 저자계측정을 위한 종형 Hall 소자의 교류구동 원리

        송명희,김정헌,박용우,류지구 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

        In this paper, the vertical Hall device which is sensitive to the magnetic fields parallel to the surface of the chip, is fabricated and characterized. The Hall voltage was ±0.2[mV] in the range of ±100[Gauss]. The current-related Magnetic sensitivity(S_(H)) was about 55[V/AT]. With an increased I_(sup), the offset voltage was also increased. Alternating Current(AC) driving system was used to process the amplification of Hall voltage and the reduction of offset and noise by the AC driving of the vertical Hall device. When the AC driving system was operated, the output of the Hall voltage was ±74.0 [mV] in the low magnetic field ranges of ±100 [Gauss], The magnetic fields resolution was 0.74[mV/Gauss].

      • 非均質 帶水層에서의 地下水 流動에 대한 2차원 數植模型에 관한 硏究

        宋在優,金智鎬,鄭祐昌 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.1

        The role and importance of groundwater are increased with the deficiency of surface water and contamination of river on the development and management of water resources. But in recent, imprudent development gave the negative impact on the aspect of the quantity and quality of groundwater. For example, the excessive pumping leads to exhaution of groundwater, and waste materials bring about contamination of groundwater. On the contaminant problem, the groundwater flow is the important media of pollutant transport and its phase is different hydraulic conductivity. Therefore, 2-D numerical model using FEM is developed. To verify this numerical model, it is compared with Theis's analytical solution for unsteady groundwater flow and existed model(used FDM). In this study, numerical model(used FEM) gives good agreement between analytical solution and existed model(used FDM). In this numerical simulation, homogeneous aquifer is supposed to use coarse sand, heterogeneous aquifer is supposed to consist of coarse sand and coarse gravel, and coarse sand and silt. The result of numerical simulation generally shows good agreements with real groundwater flow through homogeneous and heterogeneous aquifer.

      • KCI등재

        병식 평가 척도-한국판(SUMD-K)의 신뢰도와 타당도 검증

        송지영,김기태,이서경,김용희,노준호,김종우,장환일,반건호,강원섭 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

        Objectives : This study was conducted to evaluate the reliability and the validity of the Korean version of the Scale to Assessment Unawareness of Mental Disorder (SUMD-K). Methods : The subjects were 55 schizophrenic patients between ages of 26 and 58 who were recruited from the psychiatric unit of the university hospital and the out-patient clinic. The SUMD-K and insight scale of PANSS were applied to the patients. Results : The range of inter-rater (Spearman's rho) of the general items of SUMD-K were .97-.98 on the current illness and .58-.98 on the past illness. The correlation coefficient between the sum and the general items of the SUMD-K showed high scores. The concurrent validity between SUMD-K and insight item of PANSS was high (scores between .59-.96). However,the reliability and the validity of the attribution items of symptoms showed low scores compared to the current symptoms. Conclusion : The SUMD-K was confirmed in its reliability and validity. It can be a useful clinician-rating scale for evaluating insight in schizophrenic patients as well as patients with other neuropsychiatric conditions.

      • off-line 저류지 횡월류위어의 유량계수 및 적정폭 제안

        宋在偶,朴晟植,金智鎬 弘益大學校 科學技術硏究所 2005 科學技術硏究論文集 Vol.16 No.-

        The side weir is a structure that is installed to maintain uniform overflow discharge and reduce or distribute the peak flow in downstream at flood. The facility has been widely used in reducing the peak flow of flood when increasing the runoff in proportion to the development of watershed. To estimate more accurately the outflow over a sharp crested side weir, it is necessary to analyze the flow characteristics over side weir and to estimate the discharge coefficient in the weir equation. The purpose of this study is to suggest the suitable length of side weir and to propose equations for the discharge coefficients of side weir in off-line detention basin by means of hydraulic model experiments with the variations of upstream Froude number in the main channel and length of side weir. Experimental results show that the discharge coefficients depend on the upstream Froude number in the main channel and the ideal ratio of side weir length to main channel width was found to be more than 6.

      • KCI등재

        새로운 Fluorene계 발광 고분자 합성

        李愚鵬,吳東元,朴美淑,黃悳海,宋智怜,朴在均 慶北大學校 科學敎育硏究所 2004 科學敎育硏究誌 Vol.28 No.-

        Poly [2,7-(9,9-di-n-hexyl-fluorene-co-9,9-dibenzylidenylflourene)-2,7diyl] was synthesized through nikel-catalyzed coupling between 9,9-disubstituted 2,7-dibromofluorene and new fluorene-based monomer, 9,9-dibenzylidenylflurene in good yield. The polymer containing new fluorene monomer, 2,7-dibromo-9,9-dibenzylidenyflu -orene, which not only has extended π conjugation, but also has sterically hinderd sudstituents at the 9-position. The polymer obtained is found to be soluble in conventional organic solvents such as chloroform and was characterized by GPC, ^(1)H NMR and ^(13)C NMR. Also the UV absorption band showed the peak of maximum absorption at 373 nm and the photoluminescence (PL) spectra emission band showed the peak at 558 nm yellowish green region.

      • KCI등재후보

        기억력 저하를 호소하는 노인들을 대상으로 INM176를 3개월간 임상시험한 후의 치료성적 및 부작용 평가 보고

        김지혜,고선규,고효정,권영아,김성환,김재경,김태은,박재우,서민영,송영란,이인수,김도관 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.2

        Objectives : We examined the effects of INM 176 (K-l107) compared with placebo on the cognitive functions of 92 old aged subjects with cognitive impairment. Methods : This was a prospective, 12 week, double-blind, Placebo-controlled clinical trial. The elderly who achieved a score of less than 25 points on the K-MMSE or showed a high risk of Alzheimer's disease from the 7-Minute Neurocognitive Screening Battery were considered to have objective impairment and were selected as subjects for this study. The subjects were randomized to placebo or INM 176 group. The outcome measures were from the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog), the Instrumental Activities ofDaily Living (IADL) and the Korean Geriatric Depression Scale (KGDS) and two kinds of computerized priming tests. After setting the total error score in the Alzheimer's Disease Assessment Scale-Cognitive section (ADAS-cog) as the repeated measurement factor, an analysis of variance of the combined factor design was done between the placebo and INM 176 group. Results : The interaction effect of time (pre- and post-trial) and group (placebo and INM 176 group) was significant in the analysis of the ADAS-cog's total error score. The INM 176 group's total error score in the ADAS-cog decreased significantly (p<0.01), whereas the placebo group showed a slight increase. The mean changes in IADL and GDS from baseline scores favored in the INM 176 group than in the placebo group. Outcome changes ofADAS-cog, IADL, KGDS scores during the 12 week clinical trail ofINM 176 and placebo demonstrated favorable responses in the INM176 administered group. Conclusions : This is a preliminary clinical trial result of INM176 as a memory pill. Based on these results, INM176 may be a candidate molecule for the improvement of cognitive functions, including memory, Further clinical trial should demonstrate its efficacy.

      • KCI등재

        항정신병 약물이 Cyclooxygenase-2 유전자 발현과 Prostaglandin E_2 농도에 미치는 영향

        김종우,조성욱,범재명,윤도준,장환일,송지영 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2

        Objectives : Cyclooxygenase(COX) is the central enzyme in the biosynthetic pathway to prostaglandins from arachidonic acids. The action mechanism of nonsteroidal anti-inflammatory drugs is through inhibition of COX activity and prostanoid biosynthesis including prostaglandin E_2(PGE_2). The antipsychotic drugs are known having an analgesic effects, however its mechanisms of actions of action to pain control was not still clearly proved. In the present study, the effects of antipsychotic drugs(chlorpromazie and clozapine) on the production of PGE_2 and the expression of COX-2mRNA and protein in P815 cell line were studied. Methods : For that purpose, the methods of RT-PCR, western blot and prostagalndin E_2 enzymeimmunoassay were applied. Results : The results showed tha tin P815 cells treated with chlorpromazine, the level of COX2 mRNA was significantly decreased compared to the control cells. And total cellular PGE_2 levels were significantly decreased after treatment with chlorpromazine and clozapine. Conclusion : These results suggest that antipsychotic drugs have revealed their analgesic effect through the inhibition of COX-2 activity and PGE_2 production. And also, these results partly supports the excess theory of prostaglangdins in the pathogenesis of schizophrenia.

      • SCOPUSKCI등재

        딜티아젬 함유 코아 펠렛으로부터 약물의 용출에 미치는 폴록사머 함량의 영향

        이승우,감성훈,홍지웅,최기송,박은석,지상철 한국약제학회 2002 Journal of Pharmaceutical Investigation Vol.32 No.4

        In order to evaluate the effect of poloxamer 407 content on the dissolution profiles of pellets, diltiazem HCl (DTL) core pellets were prepared with poloxamer 407 (50∼90% w/w, with lactose as filler) using an extruder and a spheronizer. Any possible interaction between the drug and excipients was evaluated using DSC, IR and TLC. Dissolution tests were performed using USP basket method. In addition, scanning electron micrograph was performed to examine the surface roughness and cross sections. The release of DTL from the core pellets was decreased with increasing poloxamer 407 content. Cracks appeared on the surface of the core pellets with increasing the poloxamer 407 content, which may play a role on the retardation of the release of DTL from core pellets. There was no any significant interaction between the drug and excipients employed to prepare the core pellets.

      • 급성신부전증 이환견에 대한 복막투석 치료 1례

        김건우,이병희,김유수,심재현,김지용,이영원,김덕환,송근호 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

        A fourteen-month-old intact female Poodle was referred to the Veterinary Teaching Hospital, College of Veterinary Medicine, Chungnam National University. The patient was presented with history of vomiting, inappetence, ataxia, insomnia, tachypnea and convulsion for 5 days. Biochemical examination revealed BUN (254.2 mg/dl), creatinine (9.22 mg/dl) and phosphate (14 mg/dl). Epithelial cells of urinary tract, neutrophils, macrophages, a large number of gram negative and smaller number of gram positive bacteria were presented on urine test. Ultrasonographic findings show hyperechogenic kidney and indistinguishableness of renal cortex and medulla. Based on the results of examination described above, this case was diagnosed as acute renal failure with interstitial nephritis by urinary tract infection (UTI). Treatments with fluids therapy, diuretics, and peritoneal dialysis during hospitalization showed good results with no clinical signs.

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