여호와의 증인 환자에서 산과적 출혈 후 무수혈 치료 2예

김재령,여소진,이해혁,김정식,김태희,남계현,이권해,이임순,박진화,황경호 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Jehovah's Witness comprise a unique obstetric population. Their refusal of blood stems from an interpretation of a literal translation of the Bible, and it is this belief that puts them at an increased risk of morbidity and mortality if hemorrhage occurs. We report two cases of a Jehovah's Witness who bled massively due to obstetric hemorrhage, refused blood transfusion and had profound anemia. The patients were treated with recombinant human erythropoietin, parenteral iron and oxygen. And they were treated on an intensive care unit with intermittent positive pressure ventilation. We reviewed with literature considering the therapy for acutely anemic patients who refuse transfusion to decrease the duration of the most severe anemia.

한국판 전두엽 기능 평가 검사(Frontal Assessment Battery;K-FAB)의 신뢰도와 타당도 연구

정여진(Yeo-Jin Chung),이계성(Kye-Seong Lee),신상은(Sang-Eun Shin),김현주(Hyun-Ju Kim),성경화(Kyung-Hwa Sung) 한국중독정신의학회 2009 중독정신의학 Vol.13 No.2

The Frontal Assessment Battery (FAB) is a short cognitive and behavioral battery, comprising six subtests, for the bedside screening of global executive dysfunction. This study determined the reliability and validity of the Korean version of the FAB (K-FAB) among psychiatric patients. We enrolled 69 subjects with various psychiatric diagnosies, including alcohol dependence, and concurrently administered. Kim’s Frontal-Executive Function Neuropsychological Test (K-FENT). Forty-four subjects completed both the K-FENT and Wisconsin Card Sorting Test (WCST). Two physicians independently conducted the K-FAB. Eeach rater was blind to score of other rater. We compared the total K-FAB score to the K-FENT and WCST results to determine its concurrent validity. Finally, we obtained receiver operating characteristic (ROC) curves to determine the optimum cut-off score. The internal consistency was sufficient (Cronbach’s alpha=0.797), and the K-FAB scores were highly correlated bet-ween the two raters. The total K-FAB score correlated significantly with EIQ (r=0.665, p<0.01), the summary score of the Executive Intelligence Test (EXIT). It also correlated with total number of correct responses, perseverative errors, and total number of catergories completed in WCST. At the cut-off value 13, the K-FAB showed good sensitivity (80%) and specificity (69%). The K-FAB is a useful and easy bedside test for screen-ing frontal-executive functional impairments in a variety of psychiatric patients.

Exploring potential biomarker responses to lithium in Daphnia magna from the perspectives of function and signaling networks

Hyo Jeong Kim1,2,Jun Hyuek Yang,Hyun Soo Kim,Yeo Jin Kim,Wonhee Jang,Young Rok Seo,W. Jang,Y. R. Seo 대한독성 유전단백체 학회 2017 Molecular & cellular toxicology Vol.13 No.1

I ntensive usage of electronic appliances containing lithium batteries causes an accumulation of e-trash. Environmental exposure to lithium batteries contaminates ecosystems. In air and water, the batteries form lithium hydroxide (LiOH) on their surfaces. LiOH enters the aquatic environment and contaminates the aquatic ecosystem by being absorbed into biological organisms. In this study, in order to identify meaningful potential biomarkers that appear in response to lithium, we measured significantly up- and down-regulated genes after LiOH exposure by conducting a microarray. In addition, we explored the functions of differentially expressed daphnia genes, and we conducted a comparative analysis in other species, Daphnia spp. to humans, then analyzed the signaling pathways using the human gene set derived from daphnia sequences that are differentially expressed in response to LiOH using the NCBI-BLAST tool and Pathway studio. As a result, we identified signaling pathways and suggested several potential biomarkers that are up- or down-regulated in response to lithium. This study may contribute to the development of a biomonitoring system which can detect the ecotoxicity of lithium. Furthermore, lithium toxicity in humans can be predicted, so the study may also provide potential biomarkers of lithium exposure in humans.

특발성 혈소판감소성 자반증 환자에서 발생된 그레이브스병 1예

김여주,이규택,김상진,김휘준 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

The autoimmune nature of idiopathic thrombocytopenic purpura(ITP) and Graves' disease has been well established. In both disease, circulating immunoglobulins are believed to be involved in the pathogenesis and transplacental transfer of both disease is the ultimate proof of the importance of the humoral mechanism involved. Because of the tendency of autoimmune disease to cluster in the same individual or members of the same family, simultaneous incidence of ITP and Graves' disease is to be expected. However, in clinical practice, it has been described only rare. Therefore, we report here the case of a patient suffering sequentially from ITP and Geaves' disease with the literature.

분심기음의 항암작용 및 면역기능에 관한 연구

여대원,김진성,윤상협,류봉하,류기원 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

This study was performed to investigate the effect of Bunsimgieum on antitumor effect after sarcoma-180 cells transplantation into peritoneal cavity or left groin and immune responses on the depressed immunity induced by methotrexate in mice. The Bunsimgieum extract of 10㎎/㎏ was orally administered 14 days for antitumor effects and 21 days for immune responses. 50% inhibitory concentration(IC_(50)) of SUN-1, SUN-C4. and SUN-396 cancer cell, mean sunvival days and body weight of tumor bearing mice, and growth of tumor mass for antitumor effect; delayed type hypersentivity, hemagglutinin titer, hemolysis titer, rosette forming cells, natured killer cell activity, lymphocyte transformation. productivity of interleukin-2 and phagocytic activity for their immune responses were measured in ICR mice. Significance in antitumor effect is noted in the enlongation of mean life days and inhibition of tumor growth(p<0.01 respectively). Significance of immune responses is also noted in hemolysis titer, lymphocyte transfumotion IL-2 productivity, phagocytic activity, and natural killer cell activity at E/T ratio 100 : 1(p<0.01, respectively). Significant in rosette cell formation was seen dosage of 20㎎/㎏(p<0.01) However, Difference of body weight as antitumor effect, delayed type hypersensitivity, and hemagglutinin titer were not shown significantly. According to the above results, it could be suggested that Bunsimgieum has prominent antitumor and immunity enhancing effect.

Effect of Feeding Diets Containing an Antibiotic, a Probiotic, or Yucca Extract on Growth and Intestinal Urease Activity in Broiler Chicks

여진모,김규일 濟州大學校 農科大學 動物科學硏究所 1997 動物科學論叢 Vol.12 No.1

A 6-wk study was conducted to determine the effect of feeding diets containing an antibiotic, a probiotic, or yucca extract on daily gain, feed conversion ratio, and urease activity and ammonia production in intestinal contents of broiler chicks. Four replicates of 10 broiler chicks (average body weight, 48g) each were assigned to a control or diets containing 0.1% chloroxytetracycline (antibiotic), 0.l% Lactobacillus casei (probiotic), or 0.2% yucca extract. Feeding a diet containing the probiotic significantly (P < 0.05) increased average daily gain during the first 3-wk period compared to the control (30.7 vs 28.7 g). This increase was partly accounted for by increased feed intake. During the first 3 rvk, feeding the diet containing probiotic significantly (P < 0.05) decreased urease activity (per gram of collected contents) in small intestinal contents but not in large intestinal contents, compared with the control Urease activity determined at 6 wk of age was not significantly affected by diet. Our studies indicate that dietary probiotic decreases urease activity in the small intestinal contents of young chicks and thus may be beneficial for improving animal health and growth, especially during early life.

관절성형술 및 측두근막 이식술을 이용한 악관절 강직증의 치험례

진택현,오승환,류동목,김여갑,이상철 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1

This is a case of bony ankylosis of right temporomandibular joint with mild facial asymmetry resulted from trauma, which bring about the right condylar fracture, and corrected by interpositional arthroplasty with temporal fascia flap and coronoidectomy. The postoperative results were functionally and esthetically good, but continued osbervation is necessary to evaluation of abnormal bony growth and reankylosis.

남자 도마에서 손 짚고 앞공중돌아 540도 비틀기의 운동학적 분석

김진수,여홍철 경희대학교 체육과학연구소 1999 體育學論文集 Vol.27 No.-

The purpose of this study was to examine the biomechanical factors performing Lou Yun vaults in men's gymnastics. Three elite gymnasts were participated in this study who could perform Lou Yun vault. The vault motions were analyzed using the DLT method of the dimensional videography. The shutter speed was set 1/250 and subjects motion was videotaped with normal speed. Four range poles were used as a reference system. The vaulting motion was divided into five phases, board contact, preflight, horse touch, postflight, landing. The variables analyzed were duration, horizontal/vertical displacement, velocity, the body segment angle. The results obtained from this study were as follows; 1. The board contact time was 0.063 ± 0.015 second, preflight time was 0.267 ± 0.015 second, horse contact time was 0.417 ± 0.012 second, and posflight time was 1.407 ± 0.021 second. 2. The horizontal displacement of COM from board contact to horse touch was 122.20 ± 6.80(cm). CSM showed 129.0(cm), which is the longest displacement, YHC recorded 122.2(cm), and KDH was 115.4(cm). 3. The horizontal displacement of COM from horse take-off to landing was 458.90±11.01(cm). YHC was 471.6(cm), KDH was 452.0(cm), CSM was 453.1(cm). 4. The take-off velocity from the board displayed 6.437 ± 0.198(m/s) and the take-off velocity from the horse was 4.243 ± 0.058(m/s). 5. The take-off angle from the board was 30.57 ± 0.81° and there was not a great difference among the subjects. The blocking angle during the horse contact was 45.33 ± 4.95° and YHC displayed 49.6°, which is the largest of them.

법적인 측면에서의 간호기록 작성방법 교육이 임상간호사의 간호기록작성 지식과 이행에 미치는 효과

김은영,이여진 한국간호과학회 간호행정학회 2011 간호행정학회지 Vol.17 No.3

Purpose: The purpose of this study was to examine the effects on knowledge and performance in clinical nurses who participated in education on nursing recording focusing on the legal aspects. Method: The participants were working in medical departments in one hospital. There were 32 nurses in the experimental group and 25 in the control group. Pre-test was conducted on the two groups before education, and, in order to examine the effects of education, a post-test was conducted after three weeks. For the experimental group, the education on nursing recording focusing on legal aspects was provided as a lecture-led one-to-one training. Results: Significant differences were found between the experimental and control groups in knowledge (F=15.728, p<.001), and performance (F=42.454, p<.001). Conclusions: The results of this study indicate that education on nurse recording enhances the knowledge and performance of the nurses. Thus education on nurse recording focusing on legal aspects should be required in the area of nursing science.

당뇨병 환자에서 발생된 고열을 동반한 베체트병 1예

김여주,오정은,김상진 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Behcet's disease is a multisystem vascular inflammatory disease of unknown origin. It is characterized by recurrent aphthous stomatitis, uveitits, genital ulcer and skin lesions. All these common manifestations are self-limiting except for the ocular attack. Repeated attacks of uveitis can cause blindness. Involvement of the gastrointestinal tract, central nervous system and large vessels is less frequent, although it can be life-threatening. There is no pathognomonic laboratory test but there are clinical criteria to assist in establishing the diagnosis. One of the clinical features of Behcet's disease is low-grade fever, which usually accompanies the inflammatory manifestations of the disease. But high fever is rare. Therefore, we reported a case of Behcet's disease presented by high fever in a patient with diabetes mellitus.