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김정미,최교원,이헌주 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1
In humans, echinococcal species produce cystic lesions primarily involving the liver and lung. Echinococcal infection is caused far more commonly by Echinococcus granulosa than by E. multilocularis, which accounts for less than 5 per cent of all cases of hydatid liver disease. Hydatid disease occurs principally in sheep grazing areas, particularly in the Australia, New Zealand, Greece, Yugoslavia, Middle East, and South American countries, but with increasing migration and traveling, this disease now has a worldwide distribution. This disease is rare in Korea and only few cases have been reported. This is a clinical case report of hydatid cyst of liver caused by Echinococcus granulosus in a 52-year-old man who had been dispatched in the Vietnam from 1966 to 1968.
온도; pH, 염분 내성 및 충격이 개불, Urechis unicinctus 유생에 미치는 영향
최상덕,김호진,라성주,정형택,윤호섭,신종암,이원교 國立 麗水大學校 環境問題硏究所 1999 環境硏究論文集 Vol.2 No.-
The effect of different temperature, salinity and pH on survival rate of Urechis unicinctus's swimming embryo was examined to develop the method for the efficient seed production. In addition to, this study was designed to investigate the possibility of pollutant marker diagnosis of marine pollutions by the change in different temperature, salinity and pH. Treatment was carried out whit different temperature (5˚C, 10˚C, 17˚C, 20˚C, 25˚C,), salinity(0‰, 10‰, 20‰, 30‰, 34‰, 40‰) and pH(4, 6, 7.2, 8.2, 9.2, 10). All the swimming embryo of the temperature experiment was survived within all experiment section, but the others experiment were not. At the temperature-shock and tolerance experiment ranging from 5˚C to 25˚C the survival rate was occurred: 75%, 95%, 100%, 100%, 50%, at the ph-Shock experiment ranging from 4 to 10, the survival rate was occurred: 0%, 50%, 85%, 100%, 60%, 0%, at the pH-tolerance experiment ranging 4 to 10 the survival rate was occurred : 0%, 75% 90%, 100%, 80%, 0%, and at the salinity-shock experiment ranging from 0% to 40% the survival rate was occurred : 0% 10% 90% 95% 100% 0% , at the salinity-tolerance experiment ranging from 0% to 40% , the survival rate was occurred : 0% 0% 90% 100% 100% 0%. These results suggest, that the survival rate of larvae of Urechis unicinctus was the highest at 17˚C, 34%. pH8.2 and this Urechis unicinctus could be live at the zone of euryceious and zone of euryhalines
Antiproliferative action of metformin in endometrial stromal cell and endometrial cancer cell
( Jung Won Yoon ),( Ji Ann Jung ),( Young Eun Jun ),( Si Hyun Cho ),( Young Sik Choi ),( Byung Seok Lee ),( Seok Kyo Seo ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-
The aim of this study was to investigate the antitumor effects of metformin in inflammatory response and proliferation of endometrial stromal cells (ESCs) and endometrial cancer cell lines. Normal human ESCs were obtained from normal fertile women, who were undergoing hysterectomy for fibroids. ECC-1 and Ishikawa cells were used as endometrial cancer cell lines. The antiproliferative effects of metformin were assessed in endometrial cancer cell lines and normal human ESCs at various concentrations of metformin. Proliferation and apoptosis was assessed by flow cytometry. Metformin decreased IL-1β-induced IL-8 production and inhibited growth of ESCs in a dose-dependent manner. Metformin also exerts antiproliferative effects on both ECC-1 and Ishikawa cell in a dose-dependent manner. High dose of metformin induced apoptosis in both ECC-1 and Ishikawa cells. Our findings suggest that metformin is a potent inhibitor of cell proliferation in ESCs and endometrial cancer cell lines. Further researchs are needed to investigate metformin as a strategy for endometrial cancer prevention in patients with polycystic ovary syndrome.