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방성원,이정열,황규왕,정현,김영근 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1
Incontinentia pigmenti achromians(IPA) or Hypomelanosis of Ito is a very rare neurocutaneous syndrome which is often associated with cutaneous, cerebral, musculoskeletal and ocular abnormalities. It is assumed that it is autosomal dominant of inheritance in character. There is also a relationship between IPA and incontinentia pigmenti(IP). However, the etiology of IPA is not known. We describe a 4-year-old girl with myopia, esotropia and retinal pigmentary degeneration in addition to the hypopigmented skin lesion of IPA, and reviewed clinically the cases of IPA in this article.
네트워크를 근간으로하는 분산 시스템을 위한 CNU File Server의 구현
김봉환,황영원,이광일,김상하 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.1
A file server provides remote centralized storage of data to computers connected to it via a communication network: it facilitates data sharing among autonomous computers and support of inexpensive computers that have limited or no secondary storage. The prototype of CNU File Server(CNUFS) is designed, and the implementation aspacts and initial experiences with applications are discussed in this paper.
이종석,이성열,박영립,서용원,황규왕 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1
Follicular stem cell was assumed as a hair matrix cell. But, recently it was suggested that follicular stem cells were in the bulge portion of outer root sheath of hair follicles, and its proofs were reported. We tried to culture outer root sheath keratinocytes in the bulge portion of human hair follicles, and it would be experimental base for many factors and drugs realated with hair growth and differentiation. The outer root sheath keratinocytes were isolated from plucked human hair follicles, and could be serially passaged for up to 2 times on used biologic feeder cell layer.
Effects of α‐melanocyte‐stimulating hormone on calcium concentration in SZ95 sebocytes
Whang, Sung Won,Lee, Sang Eun,Kim, Ji Min,Kim, Hyun Jung,Jeong, Se Kyoo,Zouboulis, Christos C.,Seo, Jeong Taek,Lee, Seung Hun Blackwell Publishing Ltd 2011 Experimental dermatology Vol.20 No.1
<P><B>Abstract: </B> Melanocortins have been implicated in human sebum secretion for a long time. However, the signalling pathways of α‐melanocyte‐stimulating hormone (α‐MSH) in human sebocytes expressing melanocortin receptors (MC‐Rs) are still poorly understood. Because calcium ions play a central role in MC‐R signalling, we investigated whether α‐MSH affects calcium signalling in the immortalized human sebocyte cell line SZ95. In addition, we investigated the impact of α‐MSH on MC‐1R expression and lipid synthesis in these cells. α‐MSH increased intracellular calcium levels. α‐MSH‐mediated calcium mobilization originated from intracellular calcium stores and was mediated by inositol triphosphate. Moreover, α‐MSH increased MC‐1R immunoreactivity and lipid synthesis in SZ95 sebocytes in the presence of testosterone. Our data demonstrate that α‐MSH in human sebocytes controls a key cellular signalling pathway, the calcium ion response, which may coordinate MC‐1R‐mediated sebum secretion.</P>
조성원(Sung Won Cho),심찬섭(Chan Sup Shim),황효주(Hyo Joo Whang),함승원(Seung Won Ham),조종근(Jong Geun Cho),김익수(Ik Soo Kim) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
Mirizzi syndrome is obstruction of the common hepatic duct secondary to pressure from an impacted stone, either in the cystic duct or the neck of the gallbladder. We experienced of a 61-year-old female patient, whose clinical symptoms v:ere progressive jaun- dice, loss of appetite, pain on right upper quadrant abdomen, and fever with chill and ultrasonogram and ERCP revealed dilatation of common hepatic duct and intrahepatic duct with impacted stone on lateral wall of common hepatic duct.