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딥러닝과 영상처리 기법을 사용한 통합 지능형 주차 관제 시스템 개발
이영지(Young-Ji Lee),이희열(Hee-Yeol Lee),고태영(Tae-Young Ko),곽동훈(Dong-Hoon Kwak),김재형(Jae-Hyung Kim),김주호(Joo-Ho Kim),오승진(Seung-Jin Oh),이승호(Seung-Ho Lee) 대한전자공학회 2019 대한전자공학회 학술대회 Vol.2019 No.11
In this paper, we propose the development of an integrated intelligent parking control system using a 360° camera that has overcome the shortcomings of the existing parking control system. The system proposed in this paper consists of six items as follows. First, license plate recognition software when entering the vehicle, second, real-time parking space identification software using 360° image, third, real-time precision parking guidance software based on deep learning vehicle motion recognition, fourth, multi-license-plate recognition software using 360° image, fifth, real-time parking position identification software using 360° image, sixth, database server etc. Performance evaluation results were high in both recognition rate and time spent, and efficiency was confirmed.
Therapeutic effect of topical galectin-9 application in atopic dermatitis animal model
( Hyun Ji Lee ),( Ji Young Pak ),( Ji Hyun Lee ),( Ju Hee Han ),( Chul Hwan Bang ),( Jun Young Lee ),( Young Min Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: Galectin-9 is a protein that interacts with galactose (β-galactoside) and acts as a potent chemoattractant for eosinophils. This protein alters the T-cell balance by negatively regulating T-helper (Th) 1 and Th17 cells, resulting in Th2 polarization. Objectives: The purpose of this study is to examine the therapeutic effect of galectin-9 for atopic dermatitis (AD) animal model. Methods: NC / Nga mice (female, 14 weeks old) were sensitized with 1% 2,4-dinitrochlorobenzene (DNCB) twice a week. After sensitization, the mice were challenged with 0.4% DNCB for 1 week, and then simultaneously treated with various concentrations of galectin-9 three times a week for 3 weeks. A total of 35 mice were divided into 7 groups according to the following topical treatment modalities; non-treated, 0.4% DNCB only, vehicle (20% poloxamer 407 in PBS), 0.003%, 0.03% and 0.3% galectin-9, and 0.03% tacrolimus. Results: Ear thickness of all topically galectin-9 treated groups was significantly reduced compared with the DNCB only group (P < 0.001). Among sGal-9 treated groups only 0.3% group had a significant difference compared to the vehicle group (P < 0.01). Conclusion: These results suggest that topical application of galectin-9 may be one candidate for the treatment of AD.
Streptozotocin 유도 당뇨쥐에서 C3G 및 D3G 안토시안이 풍부한 검정콩 CJ-3호 종피 추출물의 혈중지질 개선효과
박소영(Park, So Young),박수정(Pak, Sujeong),강송주(Kang, Song Joo),김나영(Kim, Na Young),김다샘(Kim, Da Saem),김민진(Kim, Min Jin),김선아(Kim, Seon Ah),김지영(Kim, Ji Young),박소연(Park, So Yeon),박소현(Park, So Hyun),윤초롱(Youn, Ch 한국영양학회 2015 Journal of Nutrition and Health Vol.48 No.4
기존 연구에서 주로 사용하는 기타 재래종 검정콩 종피추출물 (콩단백질 혹은 총 안토시안)의 효과를 연구하는 경우와 달리, 본 연구에서는 재래종 서리태보다 C3G와 D3G 안토시안이 2배 이상 풍부한 검정콩 CJ-3호 종피추출물을 이용하였다. STZ로 유도된 당뇨쥐에 4주간 검정콩 CJ-3호 종피추출물을 처치한 결과 비록 체중감소, 혈당강하, 인슐린저항성 완화 등의 효과는 미비하지만 근육량이 유의적으로 증가하였는데 이는 일반적으로 항비만 식이요법에 따라 나타나는 근육소모를 보완하는 중요한 효과이다. STZ유도 당뇨 쥐에서 억제된 글리코겐이용률이 검정콩 CJ-3호 종피추출물에 의하여 증가한 것은 포도당이 에너지원으로 사용되면서 지방조직의 지질이용률을 억제하여 혈중 TG를 개선시켰고 간에서 HMG-CoA reductase 활성을 조절함으로써 혈청 TC를 낮추는데 기여하였다. 4주간의 투여기간을 연장한다면 향후 당뇨에서 발생하는 인슐린저항성 및 당화적 산화성억제에 따른 지질의 과산화물의 생성을 억제할 수 있는 가능성도 기대할 수 있겠다. 또한 검정콩 CJ-3호는 병 저항성이 높고 종실특성이 우수한 녹자엽 검정콩으로 생산성이 높아서 기능성에 대한 반복실험을 확인한다면 기능성식품시장의 산업화도 가능하다. 따라서 C3G와 D3G 안토시안이 풍부한 기능성 식품의 경우 당뇨, 비만 및 암 등 난치병질환에서 나타나는 혈중지질 개선을 위한 임상적 효과 또한 기대해 볼 수 있겠다. Purpose: The purpose of this study was to examine the effect of black soybean (CJ-3) testa extracts on lipid profiles in streptozotocin (STZ)-induced diabetic rats. Methods: One control group and four STZ-induced diabetic groups with different doses of black soybean (CJ-3) testa extracts treatment [0 mg/kg (diabetic control, EX), 250 mg/kg (EX-250), 500 mg/kg (EX-500), 1,000 mg/kg (EX-1000)] were orally administered for 4 weeks. Results: All CJ-3 treatment groups had remarkably lower serum triglyceride (TG) levels than that of EX group (p < 0.05) whereas hepatic TG contents did not show any differences. Results from serum total cholesterol (TC) concentrations of EX-250 and EX-1000 groups were decreased compared to EX group (p < 0.05). Furthermore, protein levels of 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase from the liver decreased in all treatment groups (p < 0.05). However, significant differences were not observed in serum glucose and insulin, and glucose transporter 4 (GLUT-4) protein expression in skeletal muscle tissue. Conclusion: These results suggest that black soybean testa extracts could be useful for improvement of hyperlipidemia and hypercholesteremia in diabetes.
Jung-Woo Lee,Jeong-Ho Cha,Sun-Hee Shin,Yun-Jeong Kim,Seul-Ki Lee,Hye-Jin Cha,Ji-Hae Kim,Ji-Hyun Ahn,Hye-Young Kim,Kyung-Ah Pak,Ji-Sung Yoon,Seo-Young Park,Choon-keun Park 한국발생생물학회 2016 발생과 생식 Vol.20 No.3
Most of the commercial devices for vitrification are directly immersed into the warming solution (WS) for increasing of warming rate. However, the previous modified cut standard straw (MCS) which has reported is difficult to immerse into the WS. The aim of this study was to investigate whether the long cut straw (LCS) could be useful as a stable tool for vitrified-warmed human blastocysts. A total of 138 vitrified-warmed cycles were performed between November 2013 and November 2014 (exclusion criteria: women ≥38 years old, poor responder, surgical retrieval sperm, and severe male factor). The artificial shrinkage was conducted using 29-gauge needles. Ethylene glycol and dimethyl sulfoxide (7.5% and 15% (v/v)) were used as cryoprotectants. Freezing and warming were conducted using the LCS tool. The cap of LCS was removed using the forceps in the liquid nitrogen (LN2) and then directly immersed into the first WS for 1 min at 37℃ (1 M sucrose). Only re-expanded blastocysts were transferred after it was cultured in sequential media for 18-20 h. A total of 294 blastocysts were warmed, and all were recovered (100%). Two hundred eighty-five embryos were survived (96.9%). The vitrifiedwarmed blastocysts of all patients were transferred without any cancellation. We were able to achieve a reasonable implantation (24.2%), following by clinical pregnancy (36.2%), which then continued to ongoing pregnancy (36.2%), and live birth (31.2%). Using LCS is achieved the acceptable rates of survival, pregnancy and live birth. Therefore, the LCS could be considered as a stable and simple tool for human embryo vitrificaton.
Lee, Jung-Woo,Cha, Jeong-Ho,Shin, Sun-Hee,Kim, Yun-Jeong,Lee, Seul-Ki,Cha, Hye-Jin,Kim, Ji-Hae,Ahn, Ji-Hyun,Kim, Hye-Young,Pak, Kyung-Ah,Yoon, Ji-Sung,Park, Seo-Young,Park, Choon-keun The Korean Society of Developmental Biology 2016 발생과 생식 Vol.20 No.3
Most of the commercial devices for vitrification are directly immersed into the warming solution (WS) for increasing of warming rate. However, the previous modified cut standard straw (MCS) which has reported is difficult to immerse into the WS. The aim of this study was to investigate whether the long cut straw (LCS) could be useful as a stable tool for vitrified-warmed human blastocysts. A total of 138 vitrified-warmed cycles were performed between November 2013 and November 2014 (exclusion criteria: women ${\geq}38$ years old, poor responder, surgical retrieval sperm, and severe male factor). The artificial shrinkage was conducted using 29-gauge needles. Ethylene glycol and dimethyl sulfoxide (7.5% and 15% (v/v)) were used as cryoprotectants. Freezing and warming were conducted using the LCS tool. The cap of LCS was removed using the forceps in the liquid nitrogen ($LN_2$) and then directly immersed into the first WS for 1 min at $37^{\circ}C$ (1 M sucrose). Only re-expanded blastocysts were transferred after it was cultured in sequential media for 18-20 h. A total of 294 blastocysts were warmed, and all were recovered (100%). Two hundred eighty-five embryos were survived (96.9%). The vitrified-warmed blastocysts of all patients were transferred without any cancellation. We were able to achieve a reasonable implantation (24.2%), following by clinical pregnancy (36.2%), which then continued to ongoing pregnancy (36.2%), and live birth (31.2%). Using LCS is achieved the acceptable rates of survival, pregnancy and live birth. Therefore, the LCS could be considered as a stable and simple tool for human embryo vitrificaton.