비파괴적 분석법을 활용한 활음진 함유 에멀젼의 인체효능평가

배지현,안성연,이해광,안순애,문성준,장이섭 한국비파괴검사학회 2004 학술대회 논문집 Vol.- No.-

최근 한방화장품이 각광을 받으면서 한방에서 말하는 피부개선효과에 대한 적절한 평가법을 찾는 연구가 많이 수행되고 있다. 본 연구에서는 피부 항산화 효과가 우수한 산사자, 당귀, 홍화, 두충, 숙지황의 초임계추출물 (활음진, 活陰眞)의 혈액순환 개선효과를 적외선 열화상 이미지 분석 및 LaserDoppler Perfusion Imager를 이용한 분석을 통해 평가하였다. 평소 손발이 차가운 여성 11명을 대상으로 활음진을 포함한 에멀젼을 1주일간 도포하게 하였으며, 도포전과 1주일간 사용한 후 피부 온도와 혈류량을 비교하였다. 그 결과 얼굴의 피부 온도가 증가하였고, 이마, 눈위, 뺨정면 부위에서 시료 사용 후 유의한 증가를 보였다. 본 연구를 통하여 활음진 성분을 포함한 에멀젼의 혈액순환 개선효과를 확인하였을 뿐만 아니라 한방적 접근을 통한 피부개선효과를 평가하는데 적절한 실험모델을 수립하였다.

중년기 여성의 스트레스 생활사건 및 자아개념과 우울과의 관계

석지혜,홍상욱,배옥현 영남대학교 지역발전연구소 1999 새마을지역개발연구 Vol.24 No.-

The purpose of this study is to grasp the life-adaptation elements of middle aged women occupy an important position in our society and to provide data which helps to solve the problems they are facing by researching the kinds of stressful life events they experience, how much stress they feel, how they feel about their self-concept, how much depression they experience and the cause and effect relations of these variables. The subjects were 447 women between the ages of 40 to 59 years old living in Taegu. The data was analyzed with the frequency, percentage, correlation, multiple regression and path analysis using the SPSS PC+ program. Major results from the study are summarized as follows : 1. The seriousness of stress of middle aged women was not that high, and the number one cause of their stress was their children's exams and schooling followed by health problems, inflication or disagreements among family members. Their self-concept score was higher than average, where as depression was marked lower. Middle aged women, however, do seem to experience depression. 2. After researching how stressful life events and self-concept effect depression and what the cause and effect relations are, it was found that depression was influenced by the husband's education level, marital life, success or achievement, religious problems, health problem and self-concept. After researching the cause and effect relations of depression, it was found that self-concept was the most influential. The wife's education, the monthly income of the family, infliction or disagreements among family members, and health problems indirectly influenced it through self-concept. Health problems was the variable which had direct and indirect influence on depression. That is to say, it is found that the lower the depression is, the more the monthly income is, the lower the stress level is by infliction or disagreements among family members and health problems, the higher self-concept is.

하수에서 분리한 합성세제 분해균의 특성

정민선,전진경,정영건,이해경,권오진,지원대,김관배 嶺南大學校 環境問題硏究所 1993 環境硏究 Vol.13 No.1

대구시와 경산시의 하수에서 음이온계 합성세제인 sodium dodecyl sulfate(SDS)와 sodium dodecylbenzene sulfonate(SDBS)를 유일한 탄소원으로 이용하는 균주 289종을 분리하고 이중 합성세제 분해력이 강한, 그람음성 간균으로 운동성인 8균주를 선정하여 그 선정균들의 특성을 조사하였다. 선정균은 40℃ 이상에서는 생육하지 못하였으며 생육 최적 pH는 균주간에 다소 차이가 있었으며 pH 4.0 이하에서는 선정균 모두 생육치 못하였다. 질소원으로는 SDS분해균의 생육에는 potassium nitrate가, SDBS 분해균의 생육에는 soytone이 좋았다. SDS 분해균인 DS-3, 6, 8, 24 및 SDBS 분해균인 BS-7, 8은 세제농도가 5.0% 이상에서도 생육이 가능하였다. 선정균들은 tetracycline에 감수성이 강한 것으로 나타났지만 penicillin에는 강한 내성을 띠는 것으로 나타났고, ??와 ??금속이온은 모든 선정균들의 생육을 억제하는 것으로 나타났다. On purpose to isolate the organisms, which would utilize detergents(sodium dodecyl sulfate, SDS and sodium dodecylbenzene sulfonate, SDBS) as a sole carbon source, from the waste water of Kyungsan and Taegu city 289 strains were isolated. Among them 8 strains, which are gram negative rods with motility and produce strong enzyme to biodegrade the synthetic detergents, were selected. The characteristics of them were investigated as follows, 8 strains were failed to grow above the temperature of 40℃ and below the pH 4.0 even though they have variable optimum pH. Potassium nitrate was very effective for the growth of SDS-biodegradable strains and soytone was effective for the growth of SDBS-biodegradable strains as a sole nitrogen source. Among 8 strains especially DS-3, DS-6, DS-8 and DS-24(SDS-biodegradation strains) and BS-7 and BS-8(SDBS-biodegradation strains) could grow above 5.0% of detergent concentration. All of 8 strains were very sensitive to tetracycline but resistant to penicillin. Selected 8 strains were inhibited by metal ions of ??(0.156mg/㎖) and ??(0.156mg/㎖).

제 2형 당뇨병 환자에서 대사증후군의 유병률 및 관련요인의 특징

박철진,박거운,박일구,신지혜,김진화,배학연,김상용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Background: People with insulin resistance has a higher risk of developing cardiovascular disease. This leads to the importance in diagnosing metabolic syndrome. The incidence of metabolic syndrome has increased significantly in korea because of an increased population of obese people and also the incidence of DM. There have been many studies done on the incidence of metabolic syndrome in the general population. Therefore, the authors have designed this study to identify the incidence of metabolic syndrome in patients with type 2 DM and also the associated characteristics in that population. Methods: The study included 169 adults over the age of 20 (84 males and 85 females) admitted to the endocrinology department of Chosun University between Jan, 1st 2005 and May, 31st 2006. Out of the people diagnosed with type 2 DM people were excluded when any of the physical measurements (height, weight, blood pressure, abdominal circumference) and blood measurements (TG, HDL-cholesterol, fasting blood sugar) were insufficient and when the patient was taking any drugs other than anti-hy-pertensive agents and oral anti-diabetic agents. Obesity and the other risk factors were defined by the Asian-Pacific guideline and 2001 ATP III of NCEP, respectively. Result: The each prevalence according to the metabolic syndrome criteria of the type 2 DM patients showed low HDL cholesterolemia with the highest incidence of 57.4% followed by hypertng1yceridemia(52.0%), obesity(40.9%) and hypertension(33.0%). The each incidence of diagnostic criteria in metabolic syndrome according to sex was different, In males, hypertriglyceridemia was the highest with the incidence of 57.7% followed by low HDL-cho1estero1emia(49.5%), obesity(40.9%) and hypertension (30.0%). In women, the incidence were low HDL-cho1estero1emia(64.8%), hyperthg1yceridemia(47.6%), obesity(45.0%) and hypertension(36.0%), in a descending order. The analysis between the diagnosis of metabolic syndrome in type 2 DM patients and the criteria showed that hyperthglyceridemia (correlative value 0.575) had the highest correlation followed by low HDL-cholesterolemia (correlative value 0.446), obesity (correlative value 0.350) and hypertension (correlative value 0.410). All the correlations were statistically significant with a p-value less than 0.01. Conclusions: Type 2 DM is a important factor of metabolic syndrome based on insulin resistance. The control of blood glucose with prevention and early diagnosis of the other factors related to metabolic syndrome in type 2 DM is important for preventing cardiovascular complications.

갑상선결절의 임상 및 초음차소견의 진단적 가치

박거운,박철진,박일구,신지혜,정중화,배학연,김상용 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Backgrounds: Thyroid nodule have been relatively common disease and it's prevalence estimated about 4-7%. Recently, high resolution ultrasonography has made the detection of small thyroid nodule possible, Increases in the detection of thyroid nodule have created a clinical dilemma on how to properly manage such thyroid nodules. We investigated the prevalence, clinical and ultrasonographic characterristics, and optimal diagnostic approach toward detected benign and malignant thyroid nodules. Methods: A retrosepctive review was undertaken on the 372 patients who was done Ultrasonograpy guided fine needle aspiration biopsy in Chosun University Hospital, Gwang-Ju, Korea between July 2003 and Spring 2005. Devided into four group such as benign and malignant thyroid nodule on the basis of size 1.5Cm. The review consisted of thyroid function test, antithyroid antibodies, thyroid autoantibodies, thyroid ultrasonography, fine needle aspiration biopsy in each group. Results: The prevalence of thyroid nodule malignancy rate was 18.0%. The prevalence of thyroid incidentaloma malignanct rate was 17.5%. There were no significant differences in age, sex, thyroid function test and size between the benign, malignant incidentalomas and nodule. Ultrasonographic characteristics, include ultrasonography index point showed meaningful diagnostic value for the detection of malignancy in thyroid nodule, Conclusion: Thyroid cancers are fairly common finding. There are no clinical difference between benign and malignant thyroid nodule; however, ultrasonographic findings can be used to decision of optimal management strategies 배경: 최근갑상선 초음파의 빈번한 시행으로 갑상선 결절의 발견이 증가하고 있다. 이러한 갑상선 결절중 특히 갑상션우연종을 임상적으로 어떻게 접근하고 치료를해야하는지는 적지 않는 문제가 되고 있다. 본 연구에서는 갑상선 우연종 및 직경 1.5 cm 이상의 갑상션결절의 유병률, 임상적 특징, 초음파특정 및 초음파의 진단적 유용성에 대해 알아 보았다. 방법: 2003년 7윌부터 2005년 3월까지 조선 대학교병원 내과 및 일반외과및 건강검진 센터를 통해 갑상선 초음파, 경동맥 초음파 및 경부 CT등을 통해 우연히 발견된 갑상션결절을 가진 372명을 대상으로 후향적 연구를 시행하였다. 크기 1.5 cm 미만의 양성및 악성 갑상선 결절군과 크기 1.5 cm 이상의 양성 및 악성결절로 그룹을 나누고 각 군에서 나이, 성별, 갑상선 기능검사, 항갑상선 항체, 갑상선 초음파 및 미세침흡인세포검사등을 검토하였고, 모든 갑상선 결절에 Koike (6)가 제한한 초음파지표 점수(Ultrasonographie index point)를 부여하여 각 군을 비교하였다. 결과: 분석한 갑상선 결절 372예 중 악성결절의 유병율은 18.0% (67예)였다. 갑상선 우연 종의 유병율은 81.5% (303예)였다. 갑상선 우연 종에서의 악성률은 17.5% (53예)로 나왔다. 크기 1.5 cm 이상의 양성 및 악성 갑상선 결절과 양성 및 악성 갑상선 우연종에서 나이, 성별, 갑상선 기능검사, 항갑상선항체에는 의미있는 차이가 없었다. 또한 양성 및 악성우연종에서 의 갑상선 결절크기에도 의미있는 차이는 보이지 않았다. 갑상선 결절의 초음파 지표점수만이 양성 및 악성우연종과 양성 및 악성갑상선 결절의 감별에 의미있는 차이를 보였다. 갑상 선우연종과 크기 1.5 cm 이상의 갑상선 결절에 서 양성을 나타내는 초음파지표점수는 각각 3 점과 4점으로 다르게 나타났다. 양성 및 악성 갑상선우연종의 감별에서 초음파 지표점수의 민감도는 93.6%, 특이도는 52.8%, 양성예측율은 92.4%로 나왔고, 진단적 효율은 86.4% 였으며 크기 1.5 cm 이상의 양성 및 악성 갑상선 결정의 감별에서 초음파지수 민감도는 92.7%, 특이도가 42.9%, 양성 예측도 86%, 효율 82.6%를 보였다. 결론: 갑상선결절에서의 양성 및 악성의 유무는 임상적으로 판단하기 힘들지만 갑상선 결절에서의 초음파 소견 및 초음파 지표 점수를 도입하면 이에 대한 감별에 도움을 줄 수 있다. 따라서 갑상선 초음파검사시 초음파지표점수의 사용은 향후 갑상선 결절의 진단 방향을 제시하는 중요한 길잡이가 될 수 있으리라 사료된다.

Comorbidities in patients with vitiligo: a systematic review and meta-analysis

( Ji Hae Lee ),( Hyun Jeong Ju ),( Ji Min Seo ),( Soo Hyung Kim ),( Ro Woo Lee ),( Seo Gyeong Lee ),( Ji Yoon Kim ),( Gyong Moon Kim ),( Jung Min Bae ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1

A New Mid-Season Peach Cultivar, ‘Misshong’

Ji Hae Jun,Kyeong Ho Chung,Ik Koo Yun,Jung Hyun Kwon,Sung Ji Hae Jun,Sung Jong Kim,Yong Bum Kwack,Kyung Bok Ma,Jung Bae Kim 한국원예학회 2009 한국원예학회 학술발표요지 Vol.2009 No.5

A case of cowden syndrome

( Ji Hae Lee ),( Ji Yoon Kim ),( Seo Gyeong Lee ),( Soo Hyung Kim ),( Ro Woo Lee ),( Hyun Jeong Ju ),( Jung Min Bae ),( Gyong Moon Kim ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2

Initial experiences of Laparoscopic surgery using the da Vinci robotic system for the benign and malignant gynecologic diseases

( Ji Hae Bae ),( Su Kyung Sung ),( Gun Oh Chong ),( Dae Gy Hong ),( Young Lae Cho ),( Il Su Park ),( Yoon Soon Lee ) 대한산부인과학회 2010 Journal of Womens Medicine Vol.3 No.1

Objective: To evaluate surgical outcomes, feasibility and safety of laparoscopic surgery using the da Vinci robotic system. Methods: Fifteen patients underwent various gynecologic robotic assisted laparoscopic surgery using the da Vinci robotic system between March 2008 and November 2009, and were assessed for surgical outcomes. This retrospective case series analysis was carried out in the department of obstetrics and gynecology at Kyungpook National University Hospital, Daegu, Korea. The main reasons for operation were myoma (n=5), followed by endometrial cancer (n=3), cervical cancer (n=4), endometriosis (n=2) and adenomyosis (n=1). Results: All patients successfully underwent various laparoscopic surgery using the da Vinci robotic system such as myomectomy, hysterectomy, radical hysterectomy, ovarian cystectomy, and staging operation with no conversion to laparotomy. The mean operating time was 184.5±54.6 minutes, the mean hemoglobin change and estimated blood loss were 1.9±0.8 g/dL and 36.3±27.1 mL. The mean time from incision to docking the robot was 10.1±6.1 minutes and the mean console time was 119.7±67.1 minutes. The length of hospital stay averaged 5.4±1.7 days. No complications requiring treatment occurred. Conclusion: Laparoscopic surgery using the da Vinci robotic system is a feasible and safe treatment modality in the benign and malignant gynecologic diseases.

K-WMS-IV 디자인 소검사의 임상적 유용성: 경도인지장애 환자의 수행 특징

배솔지 ( Bae Soul-ji ),신민영 ( Shin Min-young ),이준영 ( Lee Jun-young ),김지혜 ( Kim Ji-hae ),박광배 ( Park Kwang-bae ),황순택 ( Hwang Soon-taeg ),홍상황 ( Hong Sang-hwang ),최진영 ( Chey Jean-young ) 전북대학교 사회과학연구소 2017 지역과 세계 Vol.41 No.3

본 연구는 기억상실형 경도인지장애(amnestic Mild Cognitive Impairment; amnestic MCI) 집단과 정상 노화 집단의 시·공간 기억 기능을 비교함으로써 K-WMS-IV 디자인 소검사의 임상적 유용성을 확인하기 위해 실시되었다. 디자인 소검사의 대상, 공간, 연합기억 점수를 이용하여 집단 간 수행 양상을 비교하였으며, 두 집단을 변별하는데 있어서 이 세 하위 평가영역의 예측력과 판별력을 확인하였다. 연구 결과, 두 집단 간의 수행 차이는 즉각 조건에서 두드러지게 나타나고 있었다. 두 집단 간에 대상기억에서의 수행 차이는 유의하지 않았으나, amnestic MCI 집단은 정상노화 집단에 비해 공간기억과 연합기억의 수행이 유의하게 저조한 것으로 나타났다. 특히, 연합기억은 로지스틱 회귀분석에서 대상 기억과 공간기억의 효과를 통제한 후에도 amnestic MCI 집단을 유의하게 예측하였다. ROC 분석에서도 진단적인 정확도를 의미하는 곡선하면적(Area Under the ROC Curve, AUCs)이 공간기억과 연합기억에 대해 각각 .71과 .73으로 양호한 수준으로 확인되었다. 이러한 결과는 K-WMS-IV의 디자인 소검사의 하위점수들이 amnestic MCI 환자들을 진단하고 평가하는 데 임상적으로 유용함을 시사한다. This study was conducted to confirm the clinical utility of the Design subtest of the K-WMS-IV in detecting mild cognitive impairment, high risk of Alzheimer's dementia. We compared the performance of the patients with amnestic MCI to healthy controls in three subcomponents of Design, which were object, spatial, object-spatial binding memory. The results were as follows. First, amnestic MCI patients showed significantly lower performance in immediate spatial memory and object-location binding memory, and delayed object-location binding memory than healthy controls, whilst their object memory were intact. Second, immediate object-spatial binding memory was the only significant predictor on amnestic MCI in logistic regression analysis. Third, the Area Under the ROC Curve(AUCs) of the immediate spatial memory and object-spatial binding memory were 'fair', .71 and .74, respectively. In conclusion, the subcomponents score of the Design test was useful in detecting the characteristic pattern of the visuo-spatial memory performance in amnestic MCI, and these results suggested that the Design subtest of the K-WMS-IV could enhance the diagnostic accuracy.