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      • KCI등재

        鹿脛骨이 卵巢摘出로 誘發된 흰쥐의 骨多孔症에 미치는 影響

        姜智天,金頀哲,林康鉉,安德均 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

        The purpose of this study is to examine what are the effects of the Deer Tibia on the postmenopausal osteoporosis. In order to observe the effects of the Deer Tibia on the osteoporosis induced from ovariectomy, administered the Deer Tibia in p.o to the ovariectomized Rats, and measured the variance of weight related to osteoporosis, the variance of osteocalcin, calcium, ALP, phosphorus, GOT and GPT in serum, the variance of creatinine, calcium to creatinine rate in urine and urinary volume, the variance of the organs in weight and the variance of the bones. The results of the experiment are as follows: 1. The level of serum ALP, S-GOT and S-GPT in Deer Tibia group was showed a significant decrease in comparison with control group. The level of serum osteocalcine, calcium, phosphorus in Deer Tibia group was showed no efficiency in comparison with control group. 2. The level of urinary volume in Deer Tibia group was showed a significant increase in comparison with control group, and calcium to creatnine ratio in Deer Tibia group showed a significant increase. 3. The weight of tibia ash and the length of femur in Deer Tibia group showed no significant change. The bone density in Deer Tibia group showed a significant increased in comparison with control group. 4. Body weight in Deer Tibia group was increased in comparison with control group, but showed no efficiency. The weight of heart, liver, spleen, kidney and uterus in Deer Tibia group showed no significant change in comparison with control group. According to the above results, effects of the Deer Tibia on the aged ovariectomized rat model showed a efficiency in elevation of bone density by increasing bone mass and in prevention of renal function failure by ovariectomy. So Deer Tibia can be used for prevention and curing of the postmenopausal osteoporosis, as for it's effects, continuous clinical study is needed.

      • 부안 유천리 도자기의 과학적 분석

        강현삼,이한형,박기철,김건한,서만철,서정호,최기영 공주대학교 문화재보존과학연구소 2003 문화재과학기술 Vol.2 No.1

        전북 부안 유천리 청자요지에서 수습된 청자편 11점의 태토 및 유약에 대하여 화학조성을 분석하고, 기 발표되어진 문헌의 청자데이터들을 종합하여, 이와 비교함으로써 본 시료의 도자특성과 및 산지에 대한 정보를 유추하였다. 태토의 주요산화물 분석에는 XRF를 이용하였으며, 유약의 주요산화물분석에는 EPMA를 이용하였다. 태토 중 17개 미량성분의 분석에는 ICP-MS를 이용하였고, 자료의 비교분석에는 Seger식에 의한 방법과 주성분분석법에 의한 통계처리방법을 병행하였다. 태토의 주요산화물에 대한 비교분석결과 유천리 청자는 Seger 식과 주성분분석에서 RO_(2)와 RO+R_(2)O가 6~8 및 0.3~0.38 mole로, 또 높은 SiO_(2)함량과 낮은 Na_(2)O, CaO의 함량으로 전북지역의 데이터 범위에 분포함을 볼 수 있었다. 유약의 주요산화물에 대한 비교분석결과에서는 Seger식과 주성분분석에서 모두 명확한 지역구분이 나타나지 않았으며, 따라서 유천리 청자 역시 명확한 지역적 특성을 구분하기 어려웠다. 태토중 미량성분의 주성분분석에 의한 통계처리결과 광주 충효동 도편들을 제외하고는 뚜렷한 지역간의 구분을 관찰하기 어려웠다. The characterization of chemical properties and analogy of manufactured origin for the eleven celadon sherds collected in Yuchunri, Buan were performed by analyzing their body and glaze compositions and compared with previous data reported. The chemical compositions of the body and glaze were determined by XRF and EPMA, respectively. The trace elements of the body were also determined by ICP-MS. The Seger analysis and PCA were used to compare the major compositions of body and glaze of the potteries we found with previous data. The Celadon sherds from Yuchunri are distributed in a range of Chonnam potteries considering RO_(2) and RO+R_(2)O are 6~ 8 and 0.3 ~O.38mole, respectively and also high in SiO_(2) and low in Na_(2)O and CaO concentrations in the comparison between the potteries for the major compositions of the body. Differences of the chemical characteristics of those potteries between the provinces were not clear in comparison of the glaze compositions and trace element of the body.

      • KCI등재
      • KCI등재
      • 갈륨액체금속 이온원과 인듐액체금속 이온원의 빔 특성에 대한 연구

        현정우,임연찬,정강원,정원희,박철우,이종향,강승언 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

        본 연구에서는 인듐 액체금속이온원을 제작하여 빔 특성에 대해 연구를 하였으며, 기존에 연구를 하였던 갈륨 액체금속이온원의 빔특성과 비교 분석 하였다. 빔특성 분석을 위해 빔 안정도, 전류-전압특성곡선, 에너지 퍼짐을 측정하였다. 액체금속이온원에 사용되는 액체금속 저장소 및 바늘전극(tip)은 500μm의 직경을 갖는 텅스텐을 사용하였으며, 국내에서 제작된 제품을 사용하였다. 액체금속 저장소의 구조는 이전에 구상하여 연구가 이루어진 6개의 pre-etching된 텅스텐와이어(wire)가 묶여진 형태를 사용하였다.

      • 경계성 인격 장애 환자의 정신치료 상황에서의 거리문제

        강철중,박숙현 부산대학교 병원 암연구소 2006 부산대병원학술지 Vol.- No.20

        From the first contact between therapist and patient, establishing optimal distance is a high priority. Borderline patients repeatedly test the professional boundaries of the relationship and often directly or indirectly express a wish for a parent rather than a therapist. Early in the psychotherapy process, the therapist often feels a sense of floundering and an inner urgency to act rather than reflect. Because of the potential for pharmacotherapy to be contaminated by countertransference responses, a rational and systematic approach to medication, based on target symptoms and trait vulnerabilities, must be part of the overall treatment plan. Establishing a therapeutic frame and a contractual understanding is a useful way to construct an analytic space with the patient in which psychotherapy can take place. Matters such as fee payment, the length of sessions, the handling of vacations, the frequency of sessions, the need for psychiatric hospitalization, the management of suicidal crises, and a policy on phone calls should be part of this contract. On the other hand, a good deal of countertransference enactment can hide behind the rigid adherence to an inflexible structure. The balance between flexibility and boundaries parallels the therapist’s oscillation between playing the role of a new object in the present and an old object from the past.

      • 벤젠系 溶媒를 利用한 廢 EPS 도막 防水材 開發에 관한 基礎的 硏究

        김현수,안재철,강병희 동아대학교 건설기술연구소 1999 硏究報告 Vol.23 No.2

        This study is to investigate whether the solution which EPS Waste is melted by Toluene and Xylene in has the feasibilities as the water proofing materials. The tests with the times of absorption, permeability, bond strength, tensile strength in accordance with times of application and the rate of solution were performed and analyzed. In conclusion, the suitable soluble rate of EPS Waste is 50% and the best times of application is 3 times when it was compared with the existing waterproofing materials. there were no differences in the quality, so it has potential feasibilities to be used as waterproofing materials in the field in the futures.

      • KCI등재

        저칼슘식이로 사육한 생쥐의 골수세포 배양에 의한 파골세포양세포의 형성

        박주철,강선주,임도선,김현만,고재승 대한구강해부학회 1995 대한구강해부학회지 Vol.19 No.1

        Although it is now well established that osteoclasts are derived from mononuclear hematopoietic stem cells, most likely within the granulocyte-macrophage lineage, the exact differentiation process of osteoclast precusors has only been partially discovered. This study was carried out to investigate the following topics by examining the osteoclast-like cell formation from the calcium-deficient mouse bone marrow cells; 1) the effect of calcium deficiency on the formation of the mononuclear phagocytes and the mononuclear precusors of the osteoclast in the mouse bone marrow; 2) the effect of TNF (tumor necrosis factor)-α on the differentiation of osteoclast-like cells from the calcium-deficient mouse bone marrow culture; 3) the formation of the osteoclast-like cell from the calcium-deficient mouse bone marrow mononuclear cells and the relationship between the osteoblast cell line(MC3T3E1) and osteoclast-like cell formation; 4) formation of the osteoclast-like cells from the mononuclear cells which were col1ected from PTH-pretreated mouse bone marrow cells to investigate the relationship between PTH and calcium deficiency in osteoclast-like cell formation. Bone marrow cells were isolated from marrow of mouse feeding normal diet or calcium deficient diet for 7 and 14 days. Bone marrow mononuclear cells were fractionated by cetrifugation on Hypaque-Ficoli density gradients. PTH-pretreated mouse bone marrow mononuclear cells were obtained by collecting the nonadherent cells after the culture of normal mouse marrow cells with PTH for 6 days. The prepared cells were cultured on dentin disc at the concentration of 1.5-2 X 10^(6) cells per 0.5ml of a-MEM containing 10% FCS for 3, 5 and 7 days. Thereafter, TRAP staining, NSE staining, effect of calcitonin on the osteoclast-like cell and scanning electron microscope analysis of resorption lacunae on the dentin disc were performed. The results were as follows; 1. Number of the osteoclast precusors and mononuclear phagocytes in bone marrow was increased by calcium-deficient diet. 2. More osteoclast-like cells were formed from the calcium-deficient mouse bone marrow cells than from normal cells. 3. Formation of osteoclast-like cells was significantly stimulated by TNF-α in normal mouse bone marrow cells and calcium-deficient mouse bone marrow cells at concentration of l0ng/ml and 100ng/ml. 4. Osteoblast cell line(MC3T3E1) did not play an important role in osteoclast-like cell formation. 5. Formation of the osteoclast-like cells from the mononuclear cells which were collected from PTH-pretreated mouse bone marrow cells was similar to that of calcium-deficient mouse bone marrow mononuclear cells, which suggests that the effect of calcium deficiency in osteoclast formation may be mediated by PTH.

      • KCI등재

        남성화 암쥐의 모리스 수중 미로 수행력 : 성에 따른 공간기억력과 테스토르테론 효과의 차이

        신성현,박제민,정우영,박문일,서유나,김성곤,강철중 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

        Objectives : It is widely accepted that gonadal steroids are involved in organization and activation of sexual dimorphism in the brain areas related with spatial leaming. This study aimed to test the following hypothesis : 1) spatial memory is affected by sex, 2) this difference is related with brain differentiation by exposure to testosterone in the neonatal period, and/or 3) the sexual difference of spatial memory is the result of the interaction between organization of sexual dimorphism in the brain and the circulating testosterone after growing up. Methods : Testosterone enanthate 100 ㎍, ('androgenized') orvehicle ('control') was randomly administered to 28 female and 25 male rat pups within 24 hour of birth. The escape latencies (EL) in Morris water maze were measured in 15 and 16 week of age with vehicle ('baseline') and with 10 μmol/kg of testosterone ('with testosterone'), respectively. Each session Consis-ted of 10 trials, and means of the last 5 trials were analyzed. Results : The baseline EL of the males were significantly shorter than females regardless ofneonatal exposure to testosterone. With testosterone, EL of the androgenized females were significantly shorter than control females and comparable to those of males. Conclusion : Neonatal exposure to testosterone in female rats may develop a tesosterone-dependent male-like spatial leaming system.

      • SCOPUSKCI등재

        수종의 치과용 수복재료 및 시멘트의 radiopacity

        정현주,강병철,오원만,양홍서 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.1

        The radiopacity of six composite resins, three resin luting cements and ten filling materials were studied. The purpose was to obtain an indication of radiopacity value of different brands within each of these groups of materials and to show differences in radiopacities of filling materials and natural tooth structures. On radiographs, the optimal densities of standardized samples were determined by computer imaging system and radiopacity values of the materials were expressed in millimeter equivalent aluminum. Within the groups of materials studied, there was considerable variation in radiopacity. The composite resins of P-50, Z100 and Prisma AP.H displayed much higher radiopacities than aluminum. Panavia resin cement was shown to be similarly radiopaque to aluminum. Generally, the radiopacity of base and filling materials appeared to be higher than that of the enamel and dentin. If materials with substantial difference in radiopacity are used in combined applications for restorative treatment of teeth, lower radiopacity can interfere with the diagnosis and detection of gaps near the restoration.

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