La_{0.7}Ca_{0.3}Mn_{1-x}Ge_{x}O_{3} 합금의 자기열량효과 연구

황종순,남문철,김경섭,유성초 한국물리학회 2014 새물리 Vol.64 No.5

The magneto-caloric effect and the magnetization behavior have been analyzed in the perovskite La_{0.7}Ca_{0.3}Mn_{1-x}Ge_{x}O_{3} (x = 0.00, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, wt.%) compound. Samples were fabricated by using the conventional solid-state reaction method. X-ray diffraction measurements revealed that all the samples had a single phase with a perovskite structure. Detailed investigations of the changes in the magnetic entropy behavior of the samples with variations in T_{C} are discussed. Magnetic entropy changes, △S_{M}, of about 4.73 - 1.22 J/kg·K were obtained in the temperature range of 265 K - 160 K for the La_{0.7}Ca_{0.3}Mn_{1-x}Ge_{x}O_{3} compound. The values of △S_{M} decreased with decreasing Ge content. The variation of the magnetic entropy change is believed to be due to changes in the microstructure, which changes the magnetic part of the entropy of a solid at temperatures around the magnetic ordering temperature. 페로브스카이트 구조를 지니고 있는 란타늄 망간산화물 La_{0.7}Ca_{0.3}Mn_{1-x}Ge_{x}O_{3} (x = 0.00, 0.01, 0.02, 0.03, 0.04, 0.05, 0.06, 0.07, wt.%)의 자기열량효과에 대한 연구를 수행하였다. Mn에 Ge 을 치환함에 따른 큐리온도의 변화와 자기열량효과의 변화를 관측하였다. 시료진동형 자력계 (VSM) 를 이용하여 자기적인 특성을 측정하였으며, 큐리온도 근처에서 자기장의 변화에 따른 시료의 자기모멘트의 변화를 측정하였다. 고체상태 반응법 (solid state reaction)을 이용하여 다결정체 La_{0.7}Ca_{0.3}Mn_{1-x}Ge_{x}O_{3} 을 합성하였으며 만들어진 시료의 구조는 페로브스카이트 구조의 단일 상을 나타내었다. 시료의 큐리온도는 265 K (x = 0)에서 160 K (x = 0.07)의 범위를 가지고 있으며, Ge의 치환량이 증가함에 따라 감소하였다. 자기엔트로피, △S의 범위는 4.73 J/kg·K ^{-1}에서 1.22 J/kgcdotK^{-1}이었으며 Ge의 치환량이 증가함에 따라 감소하는 경향을 나타내었다. 이들 결과는 Ge의 조성이 증가함에 따라 강한 교환상호작용 (exchange interaction)을 나타내는 Mn-Mn 결합이 감소하고 약한 교환상호작용을 나타내는 Ge-Mn 결합이 증가함에 기인하는 것으로 여겨진다.

녹용약침(鹿茸藥鍼)이 CIA 모델 생쥐의 염증인자 생성억제에 미치는 영향

황종순,황지혜,이현진,이동건,강민주,백성욱,조현석,김경호,김갑성,Hwang, Jong-Soon,Hwang, Ji-Hye,Lee, Hyun-Jin,Lee, Dong-Gun,Kang, Min-Joo,Back, Song-Ook,Cho, Hyun-Seok,Kim, Kyung-Ho,Kim, Kap-Sung 대한침구의학회 2007 대한침구의학회지 Vol.24 No.6

Backgrounds : Rheumatoid Arthritis(RA) is known as the chronic inflammatory diseasethat induces persistent inflammation in the joint cavity. The destruction of cartilage occurs as the result of bones destoyed by pannus, several influential cytokines induced by the synovial capsulitis, varieties of proteinases, $O_2$ radicals, and the secondary degenerative changes of articular cartilage. The type 2 collagen-induced arthritis model is used in recent experimental research on rheumatoid arthritis. Cervus elaphus sibiricus (Nockyong) has the effect of relieving pain by nourishing the muscles, joints, and bones. It is also known to be efficacious in promoting and enhancing the immune system. The objective of this study was to investigate the effect of Cervus elaphus sibiricus herbal acupuncture to inhibit the generation of proinflammatory enzyme on type 2 collagen-induced arthritis. I investigated the inhibition of mRNA transcription of MIF(macrophage migration inhibitory factor), $TNF-{\alpha}$(Tumor necrosis $factor-{\alpha}$) and MMP-9 (matrix metalloproteinase-9) of Cervus elaphus sibiricus herbal acupuncture using an in vitro test. Also investigated was the inhibition of differentiation of Th 1 cells and activation of cytokines(MIF, $TNF-{\alpha}$, IL-6, MMP-9), which are known to cause initial RA ,and are also related to the morphology of the synovial membranes of the joint capsule, by an in vivo test, using CIA(collagen induced arthritis) model mice. Materials & methods : The laboratory animals used in this experiment were 4 week-old DBA female mice, weighing approximately 20 grams, and adjusted to the laboratory environment. The experiment was divided into the normal group(NOR)-no treated group, control group(CON)-CIA induced group, and sample group(SAM)-Cervus elaphus sibiricus herbal acupuncture treated group. RA was induced in the mice via injection of $50{\mu}{\ell}$ C II mixed CFA. The Cervus elaphus sibiricus herbal acupuncture solution was applied on $GB_{35}$(陽陵泉) for 26 days from the 3rd day of RA inducement. The concentration of the solution was determined via a MTT assay. To research the effect on the expression of MIF, $TNF-{\alpha}$ and MMP-9 mRNA, RT-PCR was performed on synovial membrane cells from the knee joint of CIA mice. C II induced RA knee joint's histo-chemical synovial membrane was observed using a specimen model via the Hematoxilin and Eosin dying technique. Results : The expression of mRNA of RA-related cytokines such as MIF, $TNF-{\alpha}$, and MMP-9 dosedependently decreased in the cell from the synovial membranes of the joint, which is treated with Cervus elaphus sibiricus herbal acupuncture solution. In mice treated with Cervus elaphus sibiricusherbal acupuncture, the damage of synovial membranes of the joint was lessened, and differentiation of Th 1 cells was suppressed. The activation of RA-related cytokines such as MIF was suppressed, and the generation of $TNF-{\alpha}$ and MMP-9 showed a statistically significant decreas. Conclusions : It is speculated that Cervus elaphus sibiricus herbal acupuncture has the therapeutic effect of palliating the damage of the tissue impaired by RA by inhibition of the initial RA progression and by regulating excessive differentiation of Th 1 cell as it suppresses the generation of RA-related cytokines during the highest stage of RA by acting on pro-inflammatory enzymes.

Study of the Effect of Blood-letting Cupping Treatment for Acute Ankle Sprain : A Randomize Controlled Trial

황종순,임대정,황지혜,조현석,김경호 대한침구의학회 2005 대한침구의학회지 Vol.22 No.3

목적 : 급성기 족관절 염좌 환자에 있어서 자락발관법이 실제 효과가 있는지 근거 중심 의학(Evidence Based Medicine)적으로 연구된 사례가 드물어서 이를 객관적으로 검증하기 위하여 본 연구를 시행하였다. 방법 : 골절이 배제되고, 명백한 외상력이 있으며, 발병 후 1주일 이내에 내원하였으며 다른 치료를 받지 않은 환자 29명을 대상으로 무작위로 실험군과 대조군으로 나누어 자락발관법 유무의 차이를 두고 시술하였다. 치료시작점과 3회 시술 후 Ankle-Hindfoot Scale(AHS)와 Numerical Rating Scale(NRS)을 평가하여 비교 분석하였다. 결과 : 29명중 19명이 최종 평가되었다. 자락발관법을 시행한 실험군(n=11)이 자락발관법을 시행하지 않은 대조군(n=8)에 대해 AHS와 NRS 모두 통계적으로 유의한 차이를 보였다(p=0.041, 0.026). 결론 : 급성기 족관절 염좌에 있어 자락발관법의 시행은 통증을 비롯한 증상 감소에 객관적인 효과가 있다.

유근피약침액이 Mouse 관절의 염증과 인지질 활성에 미치는 영향

황종순,김유종,김은정,조현석,이승덕,김갑성,김경호 대한침구의학회 2012 대한침구의학회지 Vol.29 No.3

Objectives : The purpose of this study was find out the therapeutic effects of Ulmus davidiana Planch pharmacopuncture(UPP) on the mice with collagen-induced rheumatoid arthritis. Methods : UPP was prepared and tested for therapeutic potential of rhematoid arthritis by measuring the inhibition of cyc1ooxgenase-2(COX-2) and phospholipase A2(PLA2) activities in mice. Results : UPP showed therapeutic effects on collagen-induced rheumatoid arthritis on week 8 and week 9. UPP also inhibited Freund’s complete adjuvant induced chronic rheumatoid arthritis in mice. UPP showed significant inhibition of type I and type II PLA2 activities in a dose dependent manner. However, PGE2 Production was not decreased with UPP and lipopolysaccharide -induced COX-2 protein expression was not inhibited by UPP. Conclusions : These results suggest that UPP has an therapeutic effects on drug induced-rheumatoic arthritis by inhibiting PLA2 activity.

頸項痛의 辨證에 관한 文獻考察

황종순,김경호 대한침구의학회 2007 대한침구의학회지 Vol.24 No.2

Objectives : The studies on variation in diagnosis on the neck and nuchal pain has not been done thoroughly as we can use it in clinical practice of these days. For this reason, I examined the variation in diagnosis mentioned in the classics of Oriental Medicine as the preceding study on standardization of variation in diagnosis on neck and nuchal pain. Methods : I gathered the twenty kinds of classics of Oriental Medicine that were computerized, the textbooks on Oriental Medicine which are being used these days, and the theses on current clinical research. After gathering these data, I analyzed these according to the variation in diagnosis. Results : The classics of Oriental Medicine on the neck and nuchal pain mentioned very much about the neck and nuchal pain occurred by the pathogenic factor of Wind, Cold, and Dampness, disharmony created by deficiency of Liver and Kidney, and pathogenic state of Meridians of Taiyang. According to the texts of these days, the differentiation of syndromes can be divided into four kinds of items such as Wind-Cold pathogen, Wind-Dampness pathogen, Phelgm-Heat, and disharmony between Qi and Blood. The theses of these days rarely mentioned about variation in diagnosis on the neck and nuchal pain. Conclusions : The differentiation of syndromes on the neck and nuchal pain can be divided into four kinds items as affection by exopathogen like Wind, Cold, Dampness, Heat, and so on, stagnation of Qi and the coagulation blood, deficient syndrome of Liver and Kidney, and deficient syndrome of Qi and Blood.

편타성 손상 후 발생한 원형탈모증 임상치험 1례

황종순,이아람,임대정,조현석,김경호,김갑성,Hwang, Jong-soon,Lee, A-ram,Lim, Dae-jung,Cho, Hyun-seok,Kim, Kyung-ho,Kim, Gab-sung 대한한방안이비인후피부과학회 2004 한방안이비인후피부과학회지 Vol.17 No.3

The clinical features and therapeutic results of alopecia areata are variable and unpredictable. For example, genetic, psychic, immunologic factors are regarded as the reason of alopecia areata. For the relationship between alopecia and whiplash injury, Dr. Guun explained that whiplash injury by the traffic accident produces cervical muscle spasm, and it makes autonomic nerve change. The tropical changes accompanied with ischemic change of scalp vessels made by this mechanism cause alopecia areata. And Yesudian reported the case of scalp alopecia as the result of ischemic change following traffic accident. We have experienced a 25-year-old woman with Alopecia areata following whiplash injury by traffic accident, and who had no risk factor of it. The patient was treated by acupuncture and physical treatment. Her hair loss, cervical angle and pain were improved through acupuncture treatment. This case of alopecia areata following whiplash injury is uncommon, so we report the mechanism of it, but should collect more cases and observations.

상생경영-신세계의 중소벤처기업 지원

황종순,Hwang, Jong-Sun 벤처기업협회 2008 벤처다이제스트 Vol.122 No.-

鹿茸藥鍼이 CIA 모델 생쥐의 염증인자 생성억제에 미치는 영향

황종순,황지혜,이현진,이동건,강민주,백성욱,조현석,김경호,김갑성 대한침구의학회 2007 대한침구의학회지 Vol.30 No.4

병원 단체급식 종사원이 지각한 근무환경이 심리적 조직유효성과 고객지향성에 미치는 영향 : 충북지역 종합병원을 중심으로

황종순(Hwang, Jong-Sun) 한국외식경영학회 2022 외식경영연구 Vol.25 No.2

본 연구는 병원 단체급식 종사원이 지각한 근무환경이 심리적 조직유효성과 환자 지향성에 어떠한 영향을 미치는지, 또한 심리적 조직유효성이 고객지향성에 어떠한 영향을 미치는지 병원 단체급식 종사원들을 대상으로 조사하였다. 본 연구의 결과는 다음과 같다. 첫째, 병원 단체급식 종사원의 근무환경요인이 직무만족에 미치는 결과 근무촉진환경, 복지환경, 고용환경이 직무만족에 유의한 영향을 미치는 것으로 나타났다. 그리고 병원 단체급식 종사원의 근무환경요인이 조직몰입에 미치는 결과는 근무촉진환경, 작업환경, 복지환경, 고용환경이 조직몰입에 유의한 영향을 미치는 것으로 나타났다. 둘째, 병원 단체급식 종사원의 근무환경요인이 고객지향성에 미치는 영향 정도를 검증한 결과는 근무촉진환경, 작업환경, 복지환경, 고용환경이 고객지향성에 유의한 영향을 미치는 것으로 나타났다. 셋째, 병원 단체급식 종사원의 심리적 조직 유효성이 고객지향성에 미치는 결과는 직무만족, 조직몰입이 고객지향성에 유의한 영향을 미치는 것으로 나타났다. This study was investigated how the perceived working environment of hospital group catering staff affects psychological organizational effectiveness and patient orientation. First, as for the results of the work environment factors of hospital group catering workers on job satisfaction, work promotion environment, welfare environment, and employment environment had a significant effect on job satisfaction. And work promotion environment, work environment, welfare environment, and employment environment had a significant effect on organizational commitment. Second, as for the effect of the working environment factors of hospital group catering workers on customer orientation, the working environment, working environment, welfare environment, and employment environment had a significant effect on customer orientation. Third, in the effect of psychological organizational effectiveness of hospital group catering workers on customer orientation, job satisfaction and organizational commitment had a significant effect on customer orientation.

조선후기 한의학에서 龔廷賢 藥性歌의 수용과 변천과정에 대한 연구

황종순(Jong Sun Hwang),최달영(Dall Yeong Choi),정한솔(Han Sol Jeong),신상우(Sang Woo Shin),하기태(Ki Tae Ha) 한의병리학회 2010 동의생리병리학회지 Vol.24 No.6