Henoch-Schönlein Purpura에서 연령에 따른 임상 양상 및 예후에 관한 고찰

홍주희,나형준,남궁미경,최승옥,한병근,정순희,김황민,Hong, Joo Hee,Na, Hyung Joon,Namgoong, Mee Kyung,Choi, Seung Ok,Han, Byng Geun,Jung, Soon Hee,Kim, Hwang Min 대한소아청소년과학회 2005 Clinical and Experimental Pediatrics (CEP) Vol.48 No.11

목 적 : $Henoch-Sch{\ddot{o}}nlein$ purpura(HSP)는 소아에 흔한 전신성 혈관염이지만, 전 연령에서 발생할 수 있다. 발병 연령에 따라 임상 증상의 차이를 보이는데, 이는 예후와 밀접한 관계가 있는 것으로 알려져 있다. 본 연구에서는 발병 연령에 따른 HSP의 임상 양상의 차이와 예후를 고찰하고, 이전에 다루어지지 않았던 청소년기의 발병에 대하여 분석해 보고자 한다. 방 법 : 연세대학교 원주의과대학 원주기독병원에서 1993년 9월부터 2003년 9월까지 HSP로 진단받고 입원 또는 외래 치료하였던 205명 환자를 대상으로 의무기록을 통한 후향적 연구를 시행하였다. 대상 환자는 연령에 따라 10세 미만을 소아군, 10세에서 19세를 청소년군, 20세 이상을 성인군으로 분류하였다. 예후 판정 기준은 HSP 신염 환자에서 추적 관찰 종료 시점의 소변 검사 및 임상 증상 기록을 근거로 신염의 소실, 경도의 신증상, 중증 이상의 신증상으로 분류하였다. 진단 당시의 나이, 성별, 계절별 발생률 및 상기도 감염의 선행 여부 등의 역학적 요인과 임상 증상, 그리고 검사 소견을 연령군 별로 비교 분석하였다. 결 과 : 대상 환자 205례에서 소아군은 149명, 청소년군은 38명, 성인군은 18명으로 평균 연령은 각각 $5.7{\pm}1.8$세, $13.5{\pm}2.4$세, $44.9{\pm}14.5$세이었다. 남녀 비는 소아와 청소년군은 1.2 : 1, 성인군은 2 : 1이었다. 상기도 감염이 선행된 경우는 소아에서 53.4%, 청소년 32.4%, 성인 33.3%이었다. 대변 잠혈 반응 검사 양성 빈도는 소아군(23.0%)과 성인군(50.0%) 사이에는 통계학적으로 유의한 차이를 보였으나(P<0.05), 소아군과 청소년군(40.0%), 그리고 청소년군과 성인군간에는 유의한 차이가 없었다. 신장 침범은 소아군 46례(30.9%), 청소년군 23례(60.5%), 성인군 15례(83.3%)에서 발생하였으며, 소아군에 비해 청소년군과 성인군에서 통계적으로 유의하게 신장 침범 빈도가 높았으나(P<0.05), 청소년군과 성인군은 유의한 차이가 없었다. HSP의 재발은 소아군 23례(15.4%), 청소년군 9례(23.7%), 성인군 3례(16.7%)가 있었다. HSP 신염 환자의 추적 관찰 종료 시 신증상의 평가에서 소아와 청소년은 신증상의 소실 또는 경증만 지속된 경우가 각각 97.8%, 87.0%로 예후가 좋았으며, 성인은 중증 이상이 60.0%를 차지하고 13.3%에서 신부전 소견을 보여 상대적으로 좋지 않은 예후를 보였다. 결 론 : 청소년기에 발병한 HSP의 예후는 소아와 같이 양호하였으나, 임상 증상에서 위장관 출혈과 신장 침범이 성인 양상을 보이기 시작하고, 재발의 빈도가 높아 향후 장기 추적 관찰이 반드시 필요할 것으로 사료된다. Purpose : $Henoch-Sch{\ddot{o}}nlein$ purpura(HSP) is the most common and benign systemic vasculitis in children. Few reports have focused on worse outcomes of HSP in adults. The age of onset is suggested as a main risk factor. We assessed the characteristics of adolescent-onset HSP. Methods : We retrospectively analyzed 205 cases presented from Aug. 1993 to Oct. 2003. Patients were classified as children(<10 years of age), adolescents(10-20 years of age), and adults(>20 years of age). Results : The mean age was $5.7{\pm}1.8years$ in 149 children, $13.5{\pm}2.4years$ in 38 adolescents, and $44.9{\pm}14.5years$ in 18 adults. The male to female ratio was 1.2 : 1 in children and adolescents, and 2 : 1 in adults. Previous upper respiratory infections were found in 53.4 percent of children, 32.4 percent of adolescents, and 33.3 percent of adults. Positivity of stool occult blood was more frequent in adults(50.5 percent) than in children(23.0 percent)(P<0.05). Renal involvement was found in 46 cases (30.9 percent) of children, 23 cases(60.5 percent) of adolescents, and 15 cases(83.3 percent) of adults. Recurrences occurred in 23 cases(15.4 percent) of children, nine cases(23.7 percent) of adolescents, and three cases(16.7 percent) of adults. Among the cases with renal involvement, 97.8 percent of children and 87.0 percent of adolescents improved to normal or asymptomatic urinary abnormalities. 60.0 percent of adults persisted with severe nephropathy and 13.3 percent progressed to renal insufficiency. Conclusion : Although the outcome of adolescent HSP was as good as children, the clinical manifestations were similar to those of adults. Adolescents had the highest rate of recurrences. Thus long term observations may be needed in adolescent onset HSP.

미각 이상 환자의 미각 역치 검사에 관한 증례 보고

홍주희,오정규,고홍섭,Hong, Ju-Hee,Oh, Jeong-Kyu,Kho, Hong-Seop 대한안면통증구강내과학회 2001 Journal of Oral Medicine and Pain Vol.26 No.2

The authors performed the taste threshold tests in two patients complaining taste problem who visited the Department of Oral Diagnosis, Seoul National University Dental Hospital. The taste thresholds were determined using a concentration series of five tastants, sucrose ( sweet ), NaCl ( salty ), citric acid ( sour ), quinine hydrochloride ( bitter ) and monosodium glutamate ( umami ). The taste solutions were diluted by half quarter logarithmic steps. The two patients showed higher taste thresholds level than normal but the taste threshold results did not coincide with the patients appeal. Further researches are needed for developing simple and precise diagnostic methods which can be applied to the patients with taste disorder.

격치고(格致藁)에 나타난 대학(大學)·중용(中庸)에 관한 고찰

홍주희,고병희,Hong, Ju-Hui,Go, Byeong-Hui 사상체질의학회 1993 사상체질의학회지 Vol.5 No.1

완전 무치악 환자에서 하악 임플란트 지지 피개의치 사용 후의 환자만족도에 관한 전향적 연구

홍주희,정겨운,신상완,방은경,Hong, Ju-Hee,Jung, Gyu-Un,Shin, Sang-Wan,Pang, Eun-Kyoung 대한치과보철학회 2015 대한치과보철학회지 Vol.53 No.1

목적: 이 연구의 목적은 하악 임플란트 지지 피개의치와 전통적인 총의치의 환자 만족도를 비교하기 위함이다. 재료 및 방법: 하악 임플란트 지지 피개의치 치료가 계획된 40명의 상하악 완전 무치악 환자(51세 - 82세)를 대상으로 하였고, 모든 환자는 저작기능, 발음, 심미, 통증, 전반적인 만족도를 기존의 총의치 장착 시와 임플란트 지지 피개의치 장착 1주 후, 12주 후에 visual analog scale법을 이용하여 답하였다. 각 시기의 만족도 비교를 위해 반복측정 분산분석(repeated-measures ANOVA)을 시행하였다(P<.05). 결과: 모든 설문 항목에서 임플란트 지지 피개의치 장착 1주 후, 12주 후에 총의치를 장착했을 때보다 높은 만족도를 보였다(P<.05). 임플란트 지지 피개의치 장착 12주 후에 저작기능, 발음, 통증, 전반적인 만족도는 장착 1주 후에 비해 증가된 결과를 보였고, 심미에 대한 만족도와 전체적인 만족도는 감소함을 나타냈으나, 통계적인 유의성을 보이지는 않았다. 결론: 임플란트 지지 피개의치는 기존의 총의치에 만족하지 못하는 환자들의 만족도를 높임으로써 환자의 삶의 질을 개선시킬 수 있는 효과적인 치료 방법 중 하나가 될 수 있으리라 생각된다. Purpose: The purpose of this prospective study was to compare the satisfaction levels of the patients worn implant supported mandibular overdentures and conventional complete dentures. Materials and methods: Full edentulous patients (n=40) who were planned to do implant supported mandibular overdentures, aged 51 to 82 years, were enrolled in this study. All subjects rated their satisfaction levels (mastication, pronunciation, esthetics, pain, and general satisfaction) of their original conventional dentures prior to treatment and their new overdentures 1 week and 12 weeks after the delivery on 10 cm visual analogue scales. Repeated-measures ANOVA was performed to compare the satisfaction level of each three period (P<.05). Results: The mean satisfaction levels of the implant supported overdentures after 1 week and 12 weeks of delivery were significantly higher than those of the conventional complete dentures in all scoring parameters (P<.05). After 12 weeks of overdenture delivery, the increase of the satisfaction levels in mastication, pronunciation, and pain and the decrease in esthetics and general satisfaction were observed in comparison with those after 1 week of delivery, however, no significant difference was found between the satisfaction levels of 1 week and 12 weeks after delivery. Conclusion: An implant supported overdenture might be one of the effective ways to give more satisfaction to patients who were not gratified with a conventional denture and eventually to improve their quality of life.

마캄의 형성과 발전

홍주희(Joo Hee Hong) 민족음악학회 2002 음악과 민족 Vol.23 No.-

`Mukam` is one of the ancient folk artistic forms, and `Maadolnuk`, its form primiticve form, spread to the whole area of Napobak in the present northern region of tienshan to the east of Shinkang around the 2nd century B.C. The vocabulary of `Mukam` was first written in the `literature of Kuja` in the 4th century and spread to the central region of China. The structure of the Mukam music was completed in the 6th and 7th century and the collection of music and dancing composed of jeol(song), Chu(musical piece) and Wolran(music and dancing) was formed. Afterards, the music of Mukam was modified and arranged in the longstanding process of succession. But great changes were not made to the musical structure. 12 Mukams in the region of Kashim, Shinkang, added two parts such as `Dastan` and `Maishruf` to the existing musical structure of Mukam in 1879 and formed the more immense collection of music and dancing. Some say that the origin of Mukam is India. It was thought that the Indian culture had an influence on Persia and Arab before Islam emerged. Seeing the records of Mukam in the books written in Perisia and Arab, they regarded it as an individual phenomenon(some musical terms were influenced by Sankrit, and the like), and conesquenlty they judged that it was influenced by India. This should be reconsidered.

산천초목 의 고찰

홍주희(Joo Hee Hong) 세계음악학회 2002 음악과 문화 Vol.6 No.-

An attempt was made to investigate the picture of Sanch`oˇnch`omok (natural scenery) by dividing it into two parts of words and music. As a result, the following conclusion was drawn: First, it could be found that the north-western districts of Korea understood Sanch`oˇnch`omok (natural scenery)... differently from Nollyang, and trees and plants is not almost sung in the present Soˇnsori of the north-western district of Korea. Second, it is thought that Sanch`oˇnch`omok (natural scenery)...in the Kyoˇnggi Province has been greatly changed. The northwestern and north-southern districts of Korea except the Cheju district all sing the part of natural scenery is luxuriant in song, whereas the Kyoˇnggi Province alone treats it in a tone of recitation. Here the picture of Ch`omok can not be discerned because the melodies collapse. Then, the existing theory that Santaryoˇng of Kyoˇnggi Province was divided into the northwestern and north-southern districts of Korea should be revised. It progresses in the melody of Kyoˇngt`ori, not Soˇdot`ori in the north-western and southern districts of Korea or Yukjabaegit`ori in the southern districts of Korea, which seems to be natural result from the fact that Sadangp`ae (touring performance group) who sang Sant`aryoˇng originally is from Ansoˇng in Kyoˇnggi Province. That is, it can be said that the part of natural scenery in Kyoˇinngi Province has changed after its division into the north-wetern and north-southern districts of Korea.

제주지역의 전래동요 지도방안 연구

홍주희(Joo-Hee Hong),한주연(Joo-Yeon Han) 한국문화교육학회 2010 문화예술교육연구 Vol.5 No.3

본 연구는 놀이를 통하여 제주도 전래동요를 활용하기 위한 과정안을 개발하기 위해 수행되었다. 이를 위하여 놀이를 통한 전래동요 수업을 실시하기 전에 전래동요 수업의 실태와 교사들의 의식을 조사하였고, 놀이를 통한 전래동요 수업을 실시하고 난 후에 교사들의 의식도 조사하였다. 연구결과 교사들은 개발된 전래동요 과정안을 통해 수업을 진행하는 것에 긍정적인 변화를 보였다. 따라서 놀이를 통한 제주도 전래동요지도가 현장의 학생들에게 적용이 된다면 보다 효율적인 전래동요 지도방법이 될 것이다. Traditional nursery rhyme gives schoolchildren the indirect experience including literary experiences and enables them to learn the language through the rhythm and cadence found in the lyrics. And the traditional nursery rhyme contains the musical, literary and educational values. If schoolchildren come to learn the traditional nursery rhyme through play, they can naturally learn these values through diverse expressive activities related to their life. For this reason, this study attempted to investigate the teaching plan of traditional nursery rhyme based on the findings of the survey on the consciousness of elementary school teachers in the Jeju area. As a result, the following conclusion was drawn:First, it was found that the teaching of traditional nursery rhymes through play led schoolchildren to take an interest and active part in classes and enabled them to learn songs. Second, it enabled schoolchildren to eliminate their repulsion to music, accept music in an interesting way and promote their music sense. Third, it enabled schoolchildren to experience the characteristic of traditional Korean music personally through the process of singing traditional nursery rhymes in a cheerful way without its direct teaching to them and to learn the characteristic of traditional nursery rhymes of the Jeju area. It is expected that a little diverse traditional nursery rhymes and plays will be collected to develop the teaching plan of traditional nursery rhymes considering the physical and spiritual level suited to the age range of all school years as well as the first and second grades of elementary school and the accompanying methodological study will be conducted in an active way.

신장(新疆) 위구르(維吾爾) 자치구에서 메시러프(麥西熱甫)의 사회적 역활

홍주희(Hong Joo-Hee) 동북아시아문화학회 2011 동북아 문화연구 Vol.1 No.27

Maxirap is mainly practiced in Xinjiang Uygur Autonomous Region of China. Maxirap, which in modem Uygur language means “get-together” or “venue,” is the developed version of the Uygur sacrificial offerings, blessings and ceremonial events of antiquity. Maxirap contains a rich collection of traditions. A complete Maxirap event includes performances like the Uygur muqam, folk songs and dances, story-singing and drama, as well as other activities such as oral literature, tournaments and games, which people enjoy and actively take part in. Maxirap is not only an important “stage” for folk artists to display their brilliant skills, but also a “court” where the host mediates conflicts and ensure the preservation of moral standards. Moreover, it is a “classroom” where people leam about their traditional customs, nature, and different experience of economic production. It is a “playground” where to entertain body and soul. Maxirap is the most important cultural venue carrier of Uygur traditions.

나노자성입자-항체 복합체를 이용한 세포 내 염색체 위치 제어

홍주희(Juhee Hong),Prashant Purwar,차미선(Misun Cha),이정훈(Junhoon Lee) 대한기계학회 2011 대한기계학회 춘추학술대회 Vol.2011 No.10

Recently, nanotechnology has been developed to a stage that makes it possible to produce, characterize, and specifically tailor the functional properties of the MNPs for biological application. This has led to various opportunities such as improving the quality of magnetic resonance imaging, hyperthermic treatment for malignant cells, drug delivery, immunoassay, and biomolecules separation. Specially, bacterial magnetic nanoparticle (BMP) has been played a role in a biomedical application. BMP has useful qualities of dispersibility and facilitative functionalization since they covered with a lipid membrane. In most studies, BMPs were generally used as a carrier which was immobilized with the specific targeting biomolecules. Thus, manipulation of biomolecules and organelles in a cell using BMP has been less developed. Here, we demonstrate the manipulation of chromosomes conjugated with BMP-antibodies complexes in a live mouse oocyte cell using the external magnetic field.

중국 신강 위구르족의 음악 문화

홍주희(Hong Chu-hee) 동북아시아문화학회 2006 동북아시아문화학회 국제학술대회 발표자료집 Vol.- No.-

In the Xinjiang region, the important place of the traffic of the ancient Silk Road, the musical characteristics of several peoples have harmonized with each other to develop into the peculiar weiwuerzu. music. Mukamu, handed down by the weiwuerzu. people of each district of xinjiang, are divided into Uyyur 12 Muqam, Turupan Mukan, Darang Muqam, Hami Muqam according to its characteristics. 4 kinds of weiwuerzu. Muqam, handed down among the weiwuerzu. people of different regions, are the suite. They begin with the 'sanpan-seochang' which is not uniform in each part and have some measure of improvisation at the time of their performance. It is thought that this it is related to the Korean musical system of Sanjo or Pansori. What is the most interesting can be said to be that the musical instrument leading rhythms in Korean music is the 'janggu'(drum shaped like a hourglass) It is 'Dafu' that plays a role of this janggu in the music of weiwuerzu. As a result of the on-spot survey of the Chinese Xinjiang region, Dafu of the several musical instruments performs a central role in several musical instrument formations in any music. And the ancient Silk Road music not only has a great effect on the artistic field of each people but also the findings of studies in each of the humanities, such as 'Culture of the Race Dwelling in the Tarim Basin', Rise and Fall of Buddhism of the Countries Bordering on Western China', 'The Life of the weiwuerzu and the Formation and Change of Peoples in the Ancient History of Silk Road' and the like have a great influence on artistic fields such as dance, drama, music and the like of the ancient countries bordering on western China and the ancient Silk Road. To know the musical culture of the Silk Road, multi- and inter-disciplinary studies should be conducted, and it is expected that many studies will be conducted concerning this field in the future.