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사상체질과 아토피성 질환 유전자의 다형성(IL-4 polymorphism)에 관한 연관성 연구
김희정,홍정미,윤유식,고병희,최선미,김선형,Kim, Hee-Jeong,Hong, Jeong-Mi,Yoon, Yoo-Sik,Koh, Byung-Hee,Choi, Sun-Mi,Kim, Sun-Hyung 사상체질의학회 2002 사상체질의학회지 Vol.14 No.2
Purpose This study was carried out to investigate the correlation between Sasang constitution and lL-4 polymorphism of Atopy gene. Methods 1. We have selected 165 cases of DNA samples from individuals with proven history of Atopy symptom and Sasang constitution. 2. The lL-4 589C-T polymorphism was genotyped by PCR-restriction fragment length polymorphism analysis. Result They were divided six groups as the history of atopy and age. There is no group shown statistical correlation in the result of constitutional lL-4 polymorphism typing. Conclusion 1. In the total groups, lL-4 polymorphism(589C-T change of 5q31-33 position) were noted 0.727 on Soumin, 0.790 on Soyangin and 0.809 on Taeumin. It was larger on Taeumin, but there is no stastical difference between. 2. In the Atopy groups, lL-4 polymorphism(589C-T change of 5q31-33 position) were noted 0.682 on Soyangin, 0.750 on Taeumin and 0.807 on Soumin. It was larger on Soumin, but there is no stastical difference between constitution.
반응표면 분석을 이용한 Salmonella enteritidis의 증식 효능 평가
홍정미,정효준,이홍근 한국환경과학회 2002 한국환경과학회지 Vol.11 No.12
This stidy was performed to investigate the single and combined effect of concentrations of garlic juice according to the pH and temperature on the growth of Salmonella enteritdis in brain heart infusion broth, and to develope Response surface model for the effect of concentrations of garlic extract. The results of electric conductibility of Salmonella enteritidis growing in the range of incubation temperature (25~42℃), PH(5.5~9.0) and concentration of garlic juice(0~0.8%) showed that a badge with high low D.T.value and concentration of garlic extract were significantly with D.T.value and concentration of garlic extract were significantly correlated with D.T.value (p<0.01). Growth of Salmonella enteritidis in the condition of 37℃ and pH7.0 presented the lowest D.T.value.
비만 개선 효과를 지닌 탄수화물 및 지방 흡수 억제 기능성 식이조성물 개발
윤유식,최선미,홍순복,홍정미,김정원,이홍석,홍성길 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.3
In a previous study, we developed a new food additive as an egg yolk antibody (IgY) against carbohydrate digestion enzymes for the regulation of blood glucose level and weight control. The IgY delayed and decreased the increment of blood glucose level after administration of sucrose in human being by 30% in 20∼30 min. We also developed a lipase inhibitor as a water extract of two kinds of herb, Platycodon grandiflorum and Solanum melongena. Twenty three volunteers were subjected to the intake of the egg yolk IgY plus the herbal extracts for 50 days. In average, the treated subjects appeared to lose 1.96 ㎏ of body weight and 3.4 ㎏ of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of egg yolk IgY and natural herbal extract improve the obesity by the decrement of body weight and body fat mass.
사상체질과 어린이 성격유형 검사를 통한 소아 비만과의 상관관계연구
최선미,홍정미,지상은,김종덕,윤유식,안규석 대한동의생리학회,대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.6
It is well known that childhood obesity induced adolescent obesity and other chronic disease such as hypertension, diabetes, hyperlipidemia and psychological problems. Thus obesity measurement and appropriate obesity care are important in child period. Therefore, the purpose of this study is to investigate correlation of Sasang constitutions and obesity as well as psychological characteristics in 45 males and 29 female students of fifth grade at Chun-ma elementary school. 20.3% of the subjects was Soeumin, 35.1% was Soyangin and 44.6% was Taeumin. In the cases of male Weight, BMI, WHR, Skinfold Thickness, Body Fat Mass, Body fat percent Abdominal fat percent in Taeumin was significantly higher than those of Soemin and Soyangin. In the cases of female Weight, BMI, Skinfold Thickness, Body Fat Mass, Body fat percent Abdominal fat percent in Taeumin was significantly higher than those of Soemin and Soyangin. Lean Body Mass(%) in Soeumin was significantly lower than those of Taeumin and Soyangin. According to the results of MMTIC, 46% of the subjects was clear and 48.9% was unclear(undetermined). The correlation of character type and Sasang constitutions was analyzed. In the cases of male, EL index and TF index was unrelated with Sasang constitutions. Most of subjects showed more preference for Extraversion(E) and Feeling (F). By the TF index, Soyangin showed more preference for Feeling(F). And for JP index, Soyangin and Taeumin showed more preference for Perceiving(P). For female, EI index, TF index and JP index was unrelated with Sasang constitutions. Most of subjects showed more preference for Extraversion(E), Feeling(F) and Perceiving(P). By the SN index, Soeumin showed more preference for Intuition(N). The correlation of character type and obesity(%) was analyzed. In the cases of male, the higher the score of extraversion, feeling, sensing, perceiving they have, the higher obesity(%) they were. In the cases of female, the higher the score of extraversion, feeling, sensing, perceving they have, the higher obesity(%) they were.