모야모야병의 수술적 치료와 연관된 합병증과 그에 대한 치료

이현욱,홍승철,Lee, Hyun Wook,Hong, Seung-Chyul 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.8

결핵성 척추염 10례의 수술적 치료에 관한 임상적 고찰

위성목,어환,남도현,이정일,김종수,홍승철,신형진,박관,김종현,Whee, Sung Mock,Eoh, Whan,Nam, Do Hyun,Lee, Jung Il,Kim, Jong Soo,Hong, Seung-Chyul,Shin, Hyung Jin,Park, Kwan,Kim, Jong-Hyun 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.11

Objects : Because of the nonspecific nature of symptoms in tuberculous spondylitis, a delay in the diagnosis can result in progressive neurologic deficits. The authors evaluate the clinical and the radiological results of the 10 cases of surgically treated tuberculous spondylitis. Clinical materials & Methods : We retrospectively analyzed the medical records of 10 patients with tuberculous spondylitis who were treated between February 1996 and March 2000. Six patients were female, and four were male. Mean age was 43 years old, and mean follow-up period was 20.5 months. All patients were treated with 12 months of antituberculous medication postoperatively, and were followed by complete blood count, ESR, spine X-ray and MRI. Results : The lumbar spine was involved in 5 patients, the thoracic in 4, and the thoracolumbar in one. The infected vertebral bodies were 2.8 in average. The associated lesions were pulmonary tuberculosis in 3 cases, and renal tuberculosis in one. Five patients were treated by anterior debridement and fusion with bone graft using anterior instrumentation, 2 with anterior debridement and fusion with bone graft(Hong Kong procedure only), 1 with Hong Kong procedure with posterior spinal instrumentation, and 2 were managed with posterior debridement and posterior spinal instrumentation. All patients improved after operation, and the average kyphotic angle decreased postoperatively. Postoperatively, one patient had a fistula at the operative site. Conclusion : The debridement and minimal level fusion of motion segment with instrument fixation is one of surgical option for tuberculous spondyltis to preserve the spine motion segment as much as possible. Spine instability and kyphosis were prevented by anterior and posterior spinal instrumentation. But, large number of cases and longer period follow-up study in future will be needed to confirm the long term results.

중추신경계의 Aspergillosis

유승훈,이정일,남도현,김종수,홍승철,신형진,박관,어환,김종현,You, Seung-Hoon,Lee, Jung-Il,Nam, Do-Hyun,Kim, Jong-Soo,Hong, Seung-Chyul,Shin, Hyung-Jin,Park, Kwan,Eoh, Whan,Kim, Jong-Hyun 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.7

Objectives : Aspergillosis of central nervous system(CNS) is a rare pathologic condition and it has been known to be difficult to diagnose and treat. We analyzed seven cases of central nervous system aspergillosis. The clinical characteristics, and the problems in diagnosis and treatment are discussed with review of previous literatures. Material and Methods : We reviewed the clinical records, radiological findings, and pathologic reports of 7 patients with aspergillosis which involved CNS. Results : Five patients were immunocompetent, and infection was related with previous operation in 4 of them. Two patients were immunocompromised and had no history of operation. Five patients had intracranial lesions and two had spinal lesions. Mean duration from the onset of initial symptom to pathologic diagnosis was 2.4 months. Mean duration from the previous operation to the onset of symptom was 9.3 months, and from the onset of symptom to diagnosis was 2.9 months in the patients who had histories of operation. All of them were treated with surgical procedures and intravenous and oral antifungal agents, resulting in cure in 6 cases. Mean duration of the treatment was 4.9 months. Conclusion : Because aspergillosis of CNS is a rare disease and is difficult to be differentiated from the pyogenic abscess or recurrent tumor, the pathologic diagnosis is very important for adequate treatment. Although the prognosis of aspergillosis of CNS has been known to be poor, adequate surgery for both diagnosis and treatment and antifungal chemotherapy resulted in good outcome.

자발성 두개강내압 저하증

공두식,김종수,박관,남도현,어환,홍승철,신형진,김종현,Kong, Doo Sik,Kim, Jong Soo,Park, Kwan,Nam, Do Hyun,Eoh, Whan,Shin, Hyung-Jin,Hong, Seung-Chyul,Kim, Jong Hyun 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.2

Objective : Spontaneous intracranial hypotension is a rarely reported syndrome of spontaneous postural headache associated with low CSF pressure and has rarely been demonstrated radiographically or surgically. But recently, it is being recognized with increasing frequency. The purpose of this study was to characterize clinical and imaging features, etiologic factors, and outcome in the spontaneous intracranial hypotension. Patients and Methods : We reviewed our experience with documented cases of spontaneous intracranial hypotension in 5 consecutive patients with orthostatic headaches from April 1998 to April 1999. Results : The mean age was 41 years(from 35 to 49 years). All patients had postural headaches, which were completely alleviated by recumbency position. Nausea, neck pain, horizontal diplopia, photophobia, and blurred vision were noted in some of the patients. Brain MRI showed diffuse pachymeningeal gadolinium enhancement, subdural collections of fluid, and descent of the brain. The opening pressure from lumbar puncture was $4cmH_2O$ or less in three of five patients whereas the opening pressure was within normal range in two patients. All patients underwent radioisotope cisternography and computerized tomographic myelography. On radioisotope cisternography, CSF leakage was suspected at the level of cervical area(1 patient), upper thoracic area(2 patients), mid-thoracic area(1 patient). Computed tomography myelography revealed extraarachnoid accumulation of contrast media(compatible finding with CSF leakage) at the level of cervical or thoracic area. In all patients, the symptoms resolved in response to supportive measures or epidural blood patch(1 patient). Conclusion : Spontaneous spinal CSF leakage is increasingly recognized as a cause of spinal postural headache. Most CSF leaks are located at the cervicothoracic junction or in the thoracic spine and can be demonstrated by variable diagnostic method. The condition is usually self-limiting and its prognosis is typically good.

Microsurgical Anatomy in Transoral Odontoidectomy

박관,이상구,조태구,남도현,이정일,김종수,홍승철,신형진,어환,김종현,Park, Kwan,Lee, Sang Koo,Cho, Tae Goo,Nam, Do-Hyun,Lee, Jung-Il,Kim, Jong-Soo,Hong, Seung-Chyul,Shin, Hyung-Jin,Eoh, Whan,Kim, Jong-Hyun The Korean Neurosurgical Society 2000 Journal of Korean neurosurgical society Vol.29 No.3

목 적 : 경구강 치상돌기제거술은 두개척추연결부위에 대한 접근법 중 중요한 수술법이나 수술상처의 문제나 수술후 뇌막염 등의 합병증의 문제점과 해부학적으로 익숙하지 않다는 점 때문에 광범위하게 사용되지 않고 있다. 이 부위의 해부학적 구조의 이해를 위해 사체해부를 통한 미세해부학을 기술하고자 한다. 방 법 : 10구의 고정 혹은 비고정 사체두부를 이용하여 경구강 치상돌기제거술을 단계적으로 시행하였다. 각 두부는 두부 고정기를 이용하여 고정하였으며, 고속드릴과 수술현미경을 이용하여 미세수술을 시행하며 각 단계별로 사진을 촬영하였다. 결 과 : 수술단계는 6단계로 나눌 수 있으며, 연구개, 후측 인두부, 근육조직, 골조직, 치상돌기 및 인대, 십자인대 및 경막으로 나눌 수 있다. 결 론 : 이 부위의 해부학적인 지식을 충분히 숙지하면 경구강 치상돌기제거술은 합병증을 피하면서 비교적 용이하게 두개척추연결부위의 다양한 병변에서 사용될 수 있을 것으로 생각된다. Objective :The transoral approach allows direct view of the ventral craniovertebral junction and provides useful management of the various lesions of this area. We present a step by step guide to the performance of the transoral excision of the odontoid process in the cadaveric model. Methods : Ten cadaver heads were used in fixed or unfixed state. We describe the relevant surgical anatomy in the cadaveric dissection and surgical technique of transoral transpharyngeal odontoidectomy. Results : The surgical procedure of transoral odontoidectomy was categorized by six steps;soft palate, posterior pharyngeal wall, muscular structures, osseous structures, odontoid process and ligaments, cruciate ligament and dura. Conclusion : With anatomical knowledge of these regions neurosurgeons can deal with wide variety of lesions in the ventral craniovertebral junction.

The Clinical Applicability of Transoral Transpharyngeal Approach to the Craniovertebral Junction Lesions

조태구,박관,조양선,백정환,남도현,김종수,홍승철,신형진,어환,김종현,Cho, Tae Goo,Park, Kwan,Cho, Yang-Sun,Baek, Chung-Hwan,Nam, Do Hyun,Kim, Jong Soo,Hong, Seung-Chyul,Shin, Hyung Jin,Eoh, Whan,Kim, Jong Hyun The Korean Neurosurgical Society 2000 Journal of Korean neurosurgical society Vol.29 No.3

목 적 : 경구적 접근법은 두개 경추이행부의 병소에 대한 유용한 접근방법이나 신경외과 의사에게는 비교적 친숙하지 않은 해부학적 구조물과 뇌척수액 누출로 인한 뇌막염의 위험성으로 인하여 많이 사용되지 않고 있다. 본원 신경외과에서는 다양한 두개 경추이행부의 병변에 대한 경구적 접근법을 시행하였으며, 수술 방법에 따른 결과 및 이의 적응증에 대해 발표하고자 한다. 방 법 : 1996년 9월부터 1999년 4월까지 총 8예의 환자에서 경구적 접근법을 시행하였다. 3명의 환자에서 선천성 기형에 의한 두개저 함입이 있었고, 2명에서는 외상성 치상돌기 골절, 2명에서는 외상성 환축추탈구, 1명에서는 비인두부위 가양성 종양을 동반하였다. 5명의 환자에서 전방 접근법 시행후 후방 골유합술을 시행하였다. 결 과 : 환자 전 예에서 양호한 결과를 보였으며 수술전 사지의 부진마비가 있었던 환자에서는 시간이 경과 함에 따라 신경학적 호전을 보였으며, 골유합술을 시행하였던 5예에서 성공적인 골유합이 관찰되었고, 연구개를 절개하였던 환자 4명중 1명이 창상 열개를 보여 재수술로 상처 치유가 가능하였다. 뇌척수액 누수는 한 예에서도 발생하지 않았다. 결 론 : 경구적 접근법은 두개 경추 이행부의 병소에 대한 유용한 접근법으로 사용될 수 있을 것으로 생각된다. Objective : Although transoral transpharyngeal approach is a very useful method for the lesions of craniovertebral junction, it is not frequently used because of anatomical unfamilarity, risk of cerebrospinal fluid(CSF) leakage, and resultant postoperative meningitis. To evaluate the usefulness of transoral transpharyngeal approach for various lesions of craniovertebral junction, clinical characteristics and the results of this approach are investigated. Methods : Transoral transpharyngeal approaches were performed in eight cases between 1996 and 1999. Among them, there were three basilar invaginations due to congenital anomalies, two odontoid type I fractures, two atlantoaxial dislocations, and one pseudotumor. Surgical methods included five cases of anterior decompression and posterior fusion, two anterior approaches for decompression and one transoral approach for biopsy. Results : This procedure allowed immediate clinical improvement in all cases. In seven patients with preoperative motor deficit showed a progressive neurological improvement. The follow-up plain x-rays demonstrated successful bony fusion in all patients. Only one patient suffered from postoperative wound dehiscence, but she completely recovered after wound revision. There was no complication of postoperative CSF leakages. Conclusions : Transoral transpharyngeal approach for the ventral lesions of craniovertebral junction, can be used as a relatively simple and effective method.

부분적 간질에서 SPECT Subtraction을 이용한 발작 중 뇌혈류 변화에 대한 연구

이향운(Hyang Woon Lee),홍승봉(Seung Bong Hong),태우석(Woo Suk Tae),김상은(Sang Eun Kim),서대원(Dae Won Seo),정송철(Seung Cheol Jeong),이지영(Ji Young Yi),홍승철(Seung Chyul Hong) 대한핵의학회 2000 핵의학 분자영상 Vol.34 No.3

N/A Purpose: To investigate the various ictal perfusion patterns and find the relationships between clinical factors and different perfusion patterns. Materials and Methods: lnterictal and ictal SPECT and SPECT subtraction were performed in 61 patients with partial epilepsy. Bath positive images showing ictal hypoperfusion and negative images revealing ictal hypoperfusion were obtained by SPECT subtraction. The ictal perfusion patterns of subtracted SPECT were classified into focal hypoperfusion, hypoperfusion-plus, combined hypoperfusion-hypoperfusion, and focal hypoperfusion only. Results: The concordance rates with epileptic focus were 91.8% in combined analysis of ictal hypoperfusion and hypoperfusion images of subtracted SPECT, 85.2% in hypoperfusion images only of subtracted SPECT, and 68.9% in conventional ictal SPECT analysis. Ictal hypoperfusion occurred less frequently in temporal lobe epilepsy (TLE) than extratemporal lobe epilepsy. Mesial temporal hypoperfusion alone was seen only in mesial TLE while lateral temporal hypoperfusion alone was observed only in neocortical TLE. Hippocampal sclerosis had much lower incidence of ictal hypoperfusion than any other pathology. Some patients showed ictal hypoperfusion at epileptic focus with ictal hypoperfusion in the neighboring brain regions where ictal discharges propagated. Conclusion: Hypoperfusion as well as hypoperfusion in ictal SPECT should be considered for localizing epileptic focus. Although the mechanisrn of ictal hypopertusion could be an intra-ictal early exhaustion of seizure focus or a steal phenomenon by the propagation of ictal discharges to adjacent brain areas, further study is needed to elucidate it. (Korean J Nucl Med 2000;34:169-82)

간질발작의 진행에 따른 발작기 SPECT 의 혈류증가 양상

신원철(Won Chul Shin),홍승봉(Seung Bong Hong),태우석(Woo Suk Tae),송영민(Young Min Shon),서대원(Dae Won Seo),김병준(Byoung Joon Kim),홍승철(Seung Chyul Hong),김상은(Sang Eun Kim) 대한핵의학회 2001 핵의학 분자영상 Vol.35 No.6

N/A N/A

청신경 초종 수술에서 골미로를 통한 접근법의 유용성

김종현,조태구,박관,박익성,남도현,이정일,조양선,홍성화,홍승철,신형진,어환,Kim, Jong Hyun,Cho, Tae Goo,Park, Kwan,Park, Ik Seong,Nam, Do-Hyun,Lee, Jung-Il,Cho, Yang-Sun,Hong, Sung Hwa,Hong, Seung-Chyul,Shin, Hyung-Jin,Eoh, Whan 대한신경외과학회 2001 Journal of Korean neurosurgical society Vol.30 No.6

Objective : To determine the feasibility of translabyrinthine approach in the vestibular schwannoma patients, the authors reviewed eighteen consecutive cases, focusing at their functional outcome and operative complications. Materials and Method : To evaluate the functional outcome, we reviewed preoperative radiological findings such as size of tumors and location of jugular bulb as well as the preoperative neurological status including audiometric analysis and cranial nerve function in 18 patients, diagnosed as vestibular schwannoma. Also the surgical outcome was evaluated according to the functional preservation of facial nerve and incidence of the surgical complication as well as the extent of surgical resection. Results : The age of patients ranged from 21 to 62 years, with a mean of 50 years. Of 18 patients operated in our center by the translabyrinthine approach, wide exposure with total removal of the mass was possible in 16 cases (88.8%). The facial nerve was anatomically preserved in 88.8%. At six-month follow-up, facial nerve function was good(Grade I-II) in 15 patients(83%) and acceptable(I-IV) in all patients. Although the jugular bulb was highly placed is five patients, gross total resection was possible without facial nerve injury in all patients by the translabyrinthine approach. One patient experienced CSF leakage after surgery, but there was no patient with disabling deficit. Conclusion : Use of the translabyrinthine approach for removal of vestibular schwannomas resulted in good anatomical and functional preservation of the facial nerve, with minimal incidence of morbidity and no mortality. In cases of high jugular bulb impacted into mastoid bone, total removal was possible by displacing the jugular bulb with Surgicel cellulose and placement of bone wax.

소뇌-교각종양 수술시 수술 중 전기생리학적 신경감시에 따른 수술 후 기능적 결과

이상구,박관,박익성,서대원,엄동옥,남도현,이정일,김종수,홍승철,신형진,어환,김종현,Lee, Sang Koo,Park, Kwan,Park, Ik Seong,Seo, Dae Won,Uhm, Dong Ok,Nam, Do-Hyun,Lee, Jung-Il,Kim, Jong Soo,Hong, Seung Chyul,Shin, Hyung Jin,Eoh, Whan,Kim, 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.6

Objectives : Intraoperative neurophysiologic monitoring(INM) is a well known useful method to reduce intraoperative neurological complications during neurosurgical procedures. Furthermore, INM is required in most cerebellopontine angle(CPA) surgery because cranial nerves or brain stem injuries can result in serious complications. Object of this study is to the correlation between the changes of intraoperative monitoring modalities during cerebellopontine angle tumor surgery and post-operative functional outcomes in auditory and facial functions. Material and Methods : Fifty-seven patients who underwent intraoperative neurophysiologic monitoring during CPA tumor surgery were retrospectively reviewed. Their lesions were as follows ; vestibular schwannomas in 42, other cranial nerve schwannomas in seven, meningiomas in five and cysts in three cases. Pre- and postoperative audiologic examinations and facial nerve function tests were performed in all patients. Intraoperative neurophysiologic monitoring modalities includes brainstem auditory evoked potentials(BAEP) and facial electromyographies(EMG). We compared the events of INM during CPA tumor surgeries with the outcomes of auditory and facial nerve functions. Results : The subjects who had abnormal changes during CPA tumor surgery were twenty cases with BAEP changes and facial EMG changes in twenty one cases. The changes of intraoperative neurophysiologic monitoring did not always result in poor functional outcomes. However, most predictable intraoperative monitoring changes were wave III-V complex losses in BAEP and continuous neurotonic activities in facial EMG. Conclusion : These results indicate that intraoperative neurophysiologic monitoring in CPA tumor surgery usually provide predictive value for postoperative functional outcomes.