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백정환,유원민,이원재,노태석,이동원 대한두개안면성형외과학회 2006 Archives of Craniofacial Surgery Vol.7 No.2
There are various surgical fixation techniques for fractures of the mandible angle due to traumatic facial injuries. Among those surgical treatment modalities, fixation methods using plates, screws, lag screws and wires have been commonly used. With the introduction of absorbable plates, the plate fixation technique has been popularized. However, plate fixation requires an external incision or an external approach using trochar for the direction of screw fixation to be perpendicular to the mandible. The external approach has disadvantages in that it leaves a scar and involves some risk to damage the marginal mandibular branch of the facial nerve. To overcome these disadvantages, the authors used a plate platform formation technique on the fractured mandible angle. The result was satisfactory with no complications. Plate platform formation technique, as performed by the authors, can be a new and simple surgical technique for stable fixation and with minimal postoperative complication by an internal approach to avoid an external scar and nerve injury.
Current status of core needle biopsy of the thyroid
백정환 대한초음파의학회 2017 ULTRASONOGRAPHY Vol.36 No.2
The Korean Society of Thyroid Radiology organized task force team and released 2016 Thyroid Core Needle Biopsy Guidelines. In this perspective, we reviewed the current role and safety of thyroid core needle biopsy. In the future, validation of the role of core needle biopsy using the new guidelines is necessary.
동종골수이식 후 재발한 급성골수성백혈병에서 항암화학요법으로 장기간 관해가 지속된 1예
백정환,김경태,김재석,어완규 KOSIN UNIVERSITY COLLEGE OF MEDICINE 2006 高神大學校 醫學部 論文集 Vol.21 No.1
급성골수성백혈병에서 동종골수이식이 성공한 뒤에 생기는 재발은 치료에 있어서 장애요인이다. 동종골수이식 후 재발의 치료에는 면역억제제의 신속한 중단, 공여자 림프구 주입(donor lymphocyte infusion, DLI), 골수이식 재시술, 면역치료, 항암화학요법 재투여 등이 있다. 저자등은 동종골수이식 후 35개월에 골수 및 양측 고환에 재발한 M2 형 급성골수성백혈병 환자를 cytarabine (100mg/m^(2) 7일간)과 idarubicin(12mg/m^(2) 3일간)으로 1주기의 재관해 항암 화학요법을 시행하여 성공적으로 관해를 유도했다. 이후 매년 시행한 골수의 광동소교잡법(FISH)에서 완전 키메리즘(chimerism), AML1/ETO RT-PCR에서 분자학적 관해를 보였다. 현재 환자는 재관해 항암화학요법 치료 후 66개월로서, 좋은 신체활동도와 완전관해를 유지하고 있다. Disease recurrence following successful bone marrow transplantation (BMT) remains a major impediment in the management of patients with acute myelogenous leukemia (AML). Approaches to treat patients in relapse after allogeneic BMT including rapid tapering of immunosuppressive agents, donor lymphocyte infusion (DLI), second BMT, immunotherapy, and reinduction chemotherapy can be considered as treat modalities. We report a case of AML M2 in relapse 35 months involving testis and bone marrow after sibling allogeneic BMT. Second remission was achieved with one cycle of reinduction chemotherapy using cytarabine, 100 mg/m^(2) for 7 days and idarubicin, 12 mg/m^(2) for 3 days. Annual bone marrow study confirmed sustained complete chimeric status and molecular remission by fluorescence in situ hybridization (FISH) and AML1/ETO RT-PCR. The patient has remained in complete response (CR) with good performance status for 66 months after reinduction chemotherapy.
백정환,하은주,최영준,성진용,김재균,송영기 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.6
To compare single-session radiofrequency ablation (RFA) and ethanol ablation (EA) for treating predominantly cystic thyroid nodules (PCTNs). This single-blind, randomized trial was approved by the Institutional Review Board of two centers and informed consent was obtained from all patients before enrollment. Fifty patients with a single PCTN (cystic portion less than 90% and greater than 50%) were randomly assigned to be treated by either RFA (25 patients) or EA (25 patients) at two hospitals. The primary outcome was the tumor volume reduction ratio (%) at the six-month follow-up and the superiority margin was set at 13% (RFA minus EA). Analysis was performed primarily in an intention-to-treat manner. The secondary outcomes were the therapeutic success rate, improvement of symptomatic and cosmetic problems, and the number of major complications. The mean volume reduction was 87.5 ± 11.5% for RFA (n = 22) and 82.4 ± 28.6% for EA (n = 24) (p = 0.710; mean difference [95% confidence interval], 5.1% [-8.0 to 18.2]), indicating no significant difference. Regarding the secondary outcomes, therapeutic success (p = 0.490), mean symptom (p = 0.205) and cosmetic scores (p = 0.710) showed no difference. There were no major complications in either group (p > 0.99). The therapeutic efficacy of RFA is not superior to that of EA; therefore, EA might be preferable as the first-line treatment for PCTNs.
전이성 난소 종양의 CT 소견과 조직학적 소견의 비교:저음영 부위를 중심으로
백정환 대한영상의학회 1996 대한영상의학회지 Vol.35 No.3
Purpose : The purpose of this study was to correlate CT and pathologic findings of metastatic ovarian tumors,with an emphasis on intratumoral low density area. Materials and methods : Twenty three metastatic ovarian tumorsin 18 patients were included in this study. The primary sites were the stomach in all the Krukenberg tumorgroup(n=10), and the colon (n=6), stomach (n=1), unknown primary site (n=1) in the non-Krukenberg group (n = 8).Low density areas which were lower than back muscle density in post enhanced CT scan were divided into twosubgroups : well-defined and ill-defined. The well-defined low density areas were subdivided into two types, roundand amorphous. Results : Well-defined low density areas on CT(n=18) corresponded on histopathological examinationto cystic degeneration(n=2), dysfunctional cysts(n=7), cystic degeneration with dysfunctional cysts(n=3), anddilated mucin producing glands(n=6). All the cystic degeneration and dysfunctional cysts, which were seen in 10 of12 (83 %) Krukenberg tumors, were round in appearance. Dilated mucin-producing glands(n=6), which were seen onlyin non-Krukenberg tumors, were amorphous(n=4), or round(n=2) in shape. Enhancement of the wall of well-defined lowdensity areas(n=8) was demonstrated only in Krukenberg tumors(n=8). Ill-defined low density areas(n=16)corresponded to myxoid degeneration(n=10) in Krukenberg tumors, and necrosis(n=6) in non-Krukenberg tumors.Conclusion : The presence of a round well-defined intratumoral low density area, or wall enhancement, whichcorresponds to cystic degeneration or dysfunctional cyst on pathology, may suggest a Krukenberg tumor in thestomach, while an amorphous well-defined low density area, which corresponds to dilated mucin producing glands, issuggestive of a non-Krukenberg tumor in extragastric organs.