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강성귀,홍복희 대한신장학회 1983 Kidney Research and Clinical Practice Vol.2 No.1
Since lysozyme is known to be fiitered through glomerulus and completely reabsorbed in renal tub- ular cells, this enzyme should be shown up in the urine of patient with renal disease. The authors is reporting the lysozyme values taken from the plasma and urine of patients suffer- ing from renal diseaser. Results are as follows. 1. In normal persons, lysozyme activity was 73. 6 ±11. 9 pg/min/ml in plasma ar.d 4. 8±3. 2 pg/min/ml in urine. 2. In 9 nephrotic syndrome patients, lysozyme activity ivas 91. 9±43. 3 pg/min/ml in plasma and 95. 9±157. 7 pg/min/ml in urine. 3. In diabetes with nephropathy, the values incr- eased both in plasma(252.8±125.6pg/min/ml) and urine (186.5±243.9pg/min/ml), while in diabetes without nephropathy, the changes of the value were not significant. 4. 1n 5 chronic renal failures, lysozyme activity was 238. 9±100. 1 mg/min/ml in plasma ond 22l. 6± 197. 9 mg/min/ml in nrinc. In 4 acute rcnal faitures, lysozyme activit' wa remarkably increased both in ptasma and In urine. The above results suggest the measurement of lysozyme in plusma and urine be helpful in the diagnosis of rcnal discase, specially in determining nephrotic coniplication in diabetes melitus.
전기엽,홍복희,강성귀 전북대학교 의과학연구소 1983 全北醫大論文集 Vol.7 No.1
Authors reported a case of myasthenia gravis associated with thymoma, 41 years old woman. By the modified Osserman's classification, it is group lll, and obtained complete remission with prednisolon and thymectomy.
박성광,홍복희,이양근,강성귀 전북대학교 의과학연구소 1982 全北醫大論文集 Vol.6 No.2
This is a presentation of 37 year old woman with mainfestation of hyperthyroidism associated with metastatic choriocarcinoma from uterine choriocarcinoma to the lung. A remission of both the neoplastic disease and the hyperthyroidism was achieved by oncolytic chemotherapy (MTX+actinomycin) and total hysterectomy. The gonadotronion exceretion and miliary nodular densities in the lung disappeared at the same time during the therapy. In the end, the thyroid function's abnormality was entirely restored and returned to euthyroid state. The results from clinical course and the responses to chemotherapy suggested that the thyroid abnormalities of the patient were secondary from the largec quantities of trophoblastic thyrotropin, which recently was proved to be humen chorionic gonadotropin.
간침생검으로 (肝針牲檢) 확진된 (確診) 각종 간암 (肝癌) 174예에서 SGOT / SGPT 비
백홍선,박성광,임창열,이용구,홍복희,안득수,손장신,박숙자 ( H S Baek,S K Park,C Y Yim,Y K Lee,B H Hong,D s Ahn,J S Son,S J Park ) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.1
The SGOT/SGPT ratios were observed in 174 cases of various histologic types of hepatoma confirmed by needle biopsy, consisted of 164 cases of primary hepatoma and 10 cases of metastatic adenocarcinoma during the period of about 4 years from Jan. 1976 to Dec. 1979 in Jeon Bug National University Hospital and Jeon Ju Presbyterian Medical Center. The results were as follows: 1. Ratio of primary hepatoma to metastatic adenocarcinoma was lg.4: 1 and ratio of hepa- tocellular carcinoma to cholangiocarcinoma was 18. 6: I. Histologic types of primary hepatic carcinoma showed 153 cases(93.3%) of hepatocellular carcinoma, 8 cases(4.9%) of cholangiocarcinoma, 2 cases(I.2%) of hepatoblastoma and a case of mixed type. 2. Sex ratios(man to woman) were 4. 7: 1 in primary hepatoma group, 4. 1: 1 in metastatic adenocarcinoma group, 4. 5: 1 in hepatocellular carcinoma group and 7: 1 in cholangiocarcin- oma group. In hepatocellular carcinoma group, the most frequent decade was 6 th, 5 th, and 7 th decade in order(The mean age was 50. 7 years). In cholangiocarcinoma group, the age distribution was peak in 4th decade(Mean age was 56. 2 years) 4 Mean values of SGOT and SGPT were 98.4 and 50.6 Karmen unit respectively in primary hepatoma group. The SGOT/SGPT ratio was l. 93>0. 48 in primary hepatoma group. 5 In metastatic adenocarcinoma group, mean values of SGOT and SGPT were 48 and 49 Karmen unit respectively and the SGOT/SGPT ratio was 0. 97. 6, None of the metastatic adenocarcinoma patients had above 13 gm% of hemoglobin. But 9.2% of primary hepatocellular carcinoma patients showed over 15. 5 gm% of hemoglobin. 7 Alkaline phosphatases in primary hepatoma group and metastatic adenocarcinoma group were 3. 7 times(8. 66 Bessay-Lowry unit) and 4. 2 times(9. 87 Bessey-Lowry unit) as normal values respectively.