A Case of Moderate Paraquat Intoxication with Pulse Therapy in the Subacute Stage of Pulmonary Fibrosis

홍기훈,정진희,어은경,Hong, Ki-Hun,Jung, Jin-Hee,Eo, Eun-Kyung Korean society of Clincal Toxicology 2008 대한임상독성학회지 Vol.6 No.2

In South Korea, attempted suicide by paraquat (PQ) intoxication is fairly common, and is lethal by pulmonary fibrosis and hypoxemia. However, the treatment of PQ poisoning is primarily supportive management. To increase the survival rate associated with PQ intoxication, many treatments have been developed. Here, we treated a case of PQ intoxication with steroid pulse therapy. A 23-year-old man was admitted to the hospital because of PQ intoxication. He drank two mouthfuls of Gramoxon (24% commercial paraquat). His vital signs were stable, but he had a throat infection, and navy blue urine in the sodium dithionite test. Standard treatment, including gastric lavage with activated charcoal was performed, and emergent hemoperfusion with a charcoal filter was initiated 11 h after PQ ingestion. Pharmacotherapy was initiated 18 h after PQ ingestion with the administration of 5 mg dexamethasone. On day 10, chest PA showed pulmonary fibrosis. Therefore, we initiated steroid pulse therapy, with 1g methylprednisolone in 100 mL of D5W administered over 1 h repeated daily for 3 days, and 1 g cyclophosphamide in 100 mL of D5W administered over 1 h daily for 2 days. On day 15, dexamethasone therapy was initiated. On day 30, pulmonary fibrosis was improved. Thus, if pulmonary fibrosis becomes exacerbated after dexamethasone therapy during the subacute stage, pulse therapy with methylprednisolone and cyclophosphamide could be helpful.

모바일 네트워크에서 로밍을 위한 계층적 인증 방법

홍기훈,정수환,Hong, Ki-Hun,Jung, Sou-Hwan 한국통신학회 2006 韓國通信學會論文誌 Vol.31 No.12C

This paper proposes a fast authentication scheme based on hierarchical key structure (HiFA) for roaming mobile nodes in both intra-domain and inter-domain. The full authentication procedure standardized in IEEE 802.11 and 802.16 is difficult to be applied to a handover since it needs a heavy operation and long delay time during a handover. Though a number of schemes were proposed to solve the problem, the existing schemes might degrade the security of authentication or impose heavy administrative burden on the Pome authentication server. The main contribution of this paper is to reduce the communication and computation overhead of the home authentication sewer without degrading the security strength of the fast roaming authentication using hierarchical authentication key structure. The proposed scheme iii this paper decentralizes the administrative burden of the home authentication server to other network entities such as a local authentication server or access point and supports the security separation of the authentication key among local authentication servers using hash key chain. 이 논문에서는 모바일 네트워크에서 이동 노드의 로밍을 위한 해시 기반의 인증 방법을 제안한다. IEEE 802.11과 802.16 기반의 인증 방법은 많은 지연 시간과 계산 과부하로 인하여 핸드오버와 로밍의 인증방법으로 적용하기 부적절하다. 따라서 다양한 방법들이 제안되었지만, 기존의 방법들은 인증의 보안을 약화시키거나 이동시마다 홈 인증 서버에 과도한 인증 부담?을 부여한다. 이 논문에서는 계층적 인증키 관리 구조를 통해 홈 인증 서버의 관리 부담 감소와 핸드오버를 위한 인증 방법의 보안 강화에 초점을 맞추고 있다. 제안하는 방법은 인증키에 해시 키 체인을 적용하여 계층적으로 관리함으로써 흠 인증 서버의 관리 부담을 로컬 인증 서버와 엑세스 포인트로 분산시키고 각 인증 서버와 엑세tm 포인트간에 인증키를 독립화하여 보안을 강화한다.

2차 근로환경조사를 이용한 취업자의 업무 관련 건강 문제로 인한 결근율

홍기훈(Ki-Hun Hong),김대성(Dae-Seong Kim),권오준(Oh-Jun Kwon),김은아(Eun-A Kim) 대한직업환경의학회 2011 대한직업환경의학회지 Vol.23 No.4

돼지 정액내의 오염 세균의 동정 및 오염된 세균의 제거

박춘근 ( Choon Keun Park ),홍기훈 ( Ki Hun Hong ),( Su Jung Son ),이용승 ( Yong Seung Lee ),한태욱 ( Tae Wook Hahn ) 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.4

Bacteriospermia is a frequent finding in fresh boar semen and can result in detrimental effects on semen quality and longevity. The objectives of this study was to evaluate types of bacterial contaminants in porcine fresh semen and the reducing effect of antibiotic and density gradient with percoll on the bacterial contaminants. Fresh semen was collected by gloved-hand method into a pre-warmed(37℃) thermostable bottle, and was inoculated onto blood agar and MacConkey agar, respectively. After incubated for 48 hour, 7.5% CO2 at 37℃, bacterial colonies were selected and identified by Gram staining, oxidase test, catalase test and finally identified using API kits and Vitek system. Aerobic culture yielded a variety of bacteria from different genera. The most prevalent contaminant of fresh semen were Leclecia adecarboxylata, Acineobacter banmanni, Staphylococcus epidermidis, Staphylococcus cohni spp urealyticus, Proteus mirabilis. Most of identified bacteria were Gram(-) and non-pathogenic bacteria. It seems that bacterial contaminants in fresh semen were seem originated from multiple sources at the stud/farm, and were from animal and non-animal origins. Gentamicin treatment did not eliminate the bacterial contaminants completely but 3 step-density gradient with percoll completely removed the bacterial contaminants in fresh semen. Therefore, future study is necessary to prove that density gradient method with percoll can eliminate bacteria in fresh semen without significantly affecting sperm viability or function.

제주-대한해협의 표층해양의 용존 탄화수소

조기웅,정경화,신종헌,김영일,정창수,홍기훈,Cho, Ki-Woong,Jung, Kyung-Hwa,Shin, Jung-Hun,Kim, Young-Il,Chung, Chang-Soo,Hong, Gi-Hoon 한국해양학회 2000 바다 Vol.5 No.4

제주-대한해협중 소흑산도에서 부산앞 대마도부근 까지의 제주도 이북의 대륙붕 해역 (33$^{\circ}$30'${\sim}$34$^{\circ}$N 125$^{\circ}$${\sim}$128$^{\circ}$E) 용존탄화수소의 분포와 성인을 조사하였다. 표층 해수중 용존탄화수소 총함량의 시 ${\cdot}$ 공간적 변이는 10배 이상이 대체로 연안에서 높고 외해에서 낮으며, 총함량은 가을에 봄보다 높다. 탄화수소의 성인을 n-alkanes과 pristane함량을 기준으로 보면 해수중 용존 탄화수소는 1998년 4월의 경우, 황해남부(125$^{\circ}$E) 해역에서는 식물플랑크톤기원 및 석유기원 탄화수소가 우세하고, 남해에서는 육상기원과 석유기원이 우세하다. 그리고 1998년 9월에는 남해에 식물플랑크톤과 석유기원이 우세하게 나타났다. Dissolved aliphatic hydrocarbon concentrations in the surface seawater were investigated to describe their distribution and elucidate their sources in the Cheju-Korea Straits region (33$^{\circ}$30‘-34$^{\circ}$N 125$^{\circ}$-128$^{\circ}$E). Seawater sampling was made in spring and autumn in 1998. A large temporal and spatial variability were observed in the dissolved hydrocarbon concentrations in the region. The sources of dissolved hydrocarbons in seawater were elucidated based on the molecular concentrations of n-alkanes and pristane. Dissolved hydrocarbons in the surface water appears to be largely originated from phytoplankton and petroleum in the southern Yellow Sea (125$^{\circ}$), and terrigenous and petrogenic in the Cheju-Korea Straits region in April 1998. In September 1998, dissolved hydrocarbons in the surface waters were largely derived from phytoplanktons and terrestrial material in the Cheju-Korea Soaits region.

여성 정치후보자의 미디어 프레임에 따른 남녀 수용자 인식 차이 연구

박노일(Noh-Il Park),한정호(Jung-Ho Han),홍기훈(Ki-Hun Hong) 한국언론학회 2007 한국언론학보 Vol.51 No.2

응급의학과 전공의가 시행한 흉관 삽입술의 합병증에 대한 고찰

조대윤 ( Dai Yun Cho ),손동섭 ( Dong Suep Sohn ),전영진 ( Young Jin Cheon ),홍기훈 ( Ki Hun Hong ) 대한외상학회 2012 大韓外傷學會誌 Vol.25 No.2

Purpose: A tube thoracostomy is an invasive procedure that places patients at risk for complications. Tube thoracostomies are frequently performed by emergency medicine residents. Thus, the purpose of the study was to assess both the complication rate for tube thoracostomies performed by emergency medicine residents and the factors associated with these complications. Methods: A retrospective chart review of all patients who had undergone a tube thoracostomy performed by emergency medicine residents between January 2008 and February 2009 was conducted at a university hospital. Complications were divided into major and minor complications and into immediate and delayed complications. Complications requiring corrective surgical intervention, requiring the administration of blood products, or involving situations requiring intravenous antibiotics were defined as major. Complications that were detected within 2 hours were defined as immediate. Results: Tube thoracostomies were performed in 189 patients, and 70 patients(37%) experienced some complications. Most complications were immediate and minor. In multiple logistic regressions, BMI, hypotension and resident seniority were significantly associated with complications. Conclusion: The prevalence of complications was similar to these in previous reports on the complications of a tube thoracostomy. Most complications from tube thoracostomies performed by emergency medicine residents were immediate and minor complications. Thus, emergency medicine residents should be allowed to perform closed tube thoracostomies instead of thoracic surgeons. (J Korean Soc Traumatol 2012;25:37-43)

중소사업장 보건관리 담당자의 의료정보보호에 대한 인식 및 실천도

정수진(Soo-Jin Jeong),김민(Min Kim),이채관(Chae-Kwan Lee),이창희(Chang-Hee Lee),손병철(Byung-Chul Son),김대환(Dae-Hwan Kim),김정호(Jeong-Ho Kim),이종태(Jong-Tae Lee),장구락(Goo-Rak Chang),홍기훈(Ki-Hun Hong),서춘희(Chun-Hui Suh) 대한직업환경의학회 2011 대한직업환경의학회지 Vol.23 No.1