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건선에 효과적인 한약 처방 탐색 - 지질 대사를 중심으로
한창이,김준동,서광일,김규석,김윤범,Han, Chang-Yi,Kim, Jundong,Seo, Gwang-Yeel,Kim, Kyu-Seok,Kim, Yoon-Bum 대한한방안이비인후피부과학회 2021 한방안이비인후피부과학회지 Vol.34 No.3
Objectives : The purpose of this study is to investigate the possibility of using herbal medicine for the management of psoriasis focusing on lipid metabolism. Methods : We reviewed studies about pathophysiology, and medical treatment of psoriasis, the relationship between psoriasis and metabolic syndrome and lipid metabolism, and herbal medicine on Pubmed and Google scholar. Results : Psoriasis is a chronic multi-organ inflammatory disease not limited to skin, and steroids, immuno-suppressants, and biological agents are used. It is known that psoriasis and metabolic syndrome act as mutual risk factors, and lipid metabolism are involved in psoriasis. The effects of various single herbal preparations and complex herbal extract, decoction on improving lipid metabolism have been consistently reported, and there was an improvement of psoriatic skin lesions and improvement of blood lipid levels through herbal medicine. Conclusions : Herbal medicine research in psoriasis has focused on the anti-inflammatory effect and the suppression effect of certain immune mediators. However, considering that psoriasis is affected by lipid metabolism and side effects of Western medicines, the use of herbal medicines for the purpose of controlling lipid metabolism in psoriasis is useful in aspects of reducing side effects of concurrent Western medicine, improving the severity of psoriasis, and managing metabolic risk factors.
한의과대학 실습 만족도 조사 - 의사-환자 역할극, 모의 CPX를 중심으로 -
한창이,강동원,박중군,김봉현,김규석,김윤범,남혜정 대한한방안이비인후피부과학회 2020 한방안이비인후피부과학회지 Vol.33 No.1
Objectives : The purpose of this study is to find an effective clerkship process for the implementation of participatory clinical practice that is practically applicable to most Colleges of Korean Medicine. Methods : Taking the 4th-grade students of the College of Korean Medicine, Kyung Hee University in 2019 as a subject, we conducted Role-playing and simulated CPX in the department of Ophthalmology, Otolaryngology and Dermatology and conducted a satisfaction survey through a questionnaire. Results:1.The preliminary expectations for overall practice and Ophthalmology, Otolaryngology and Dermatology practice did not differ significantly. 2.The satisfaction, data adequacy, feedback adequacy, and usefulness of Ophthalmology, Otolaryngology and Dermatology course were 79.4%, 80.8%, 87.6%, and 86.5%, respectively. 3.When comparing the Role-playing of Ophthalmology, Otolaryngology with mock CPX of Dermatology, data relevance level was similar, feedback adequacy level was higher in mock CPX, satisfaction and usefulness level were higher in Role-playing. Conclusion : Comparing Role-playing with the simulated CPX method, Role-playing is a relatively realistic form than the CPX method, and moreover students showed higher satisfaction and usefulness in Role-playing.
아토피 피부염 증례 연구 분석 -한약 처방을 중심으로-
한창이,박중군,강동원,박소영,김봉현,김윤범,김규석 대한한방안이비인후피부과학회 2019 한방안이비인후피부과학회지 Vol.32 No.3
Objectives : The purpose of this study is to investigate the use of herbal medicine for the treatment of atopic dermatitis in cases and to find the general tendency of herbal medicine treatment and to establish the primary treatment direction of Atopic dermatitis. Methods : In the domestic databases, Oriental medicine Advanced Searching Integrated System(OASIS), Korea Traditional Knowledge Portal(KTKP), National Discovery for Science Leader(NDSL), Research Information Sharing Service(RISS), we selected among the papers published in the last 20 years using search terms related to "Atopic dermatitis & Cases". Reports based on Sasang constitutional medicine and Six meridian pattern identification were excluded and a total of 21 papers were finally selected. Results : 113 herbal medicines were retrieved from 21 papers. The most commonly used herbs are Scutellariae Radix(黃芩), Rehmanniae Radix(地黃), and Glycyrrhizae Radix et Rhizoma(甘草). Atractylodis Rhizoma(蒼朮), Akebiae Caulis(木通), Smilacis Rhizoma(土茯苓), Paeoniae Radix(芍藥) used mostly when Oozing exists, Trichosanthis Radix(瓜蔞), Asparagi Radix(天門冬), Persicae Semen(桃仁), Carthami Flos(紅花) used mostly when Dryness, Lichenification, and Pigmentation exist. The average score of SCORAD index was improved after Herbal medicine treatment. Conclusion : Through this study, we could find out the tendency of herbal medicine to treat Atopic dermatitis along with Symptoms.
피부과 영역에서 steroid 테이퍼링 및 남용 완화를 위한 한약 사용에 대한 고찰
한창이,김준동,강동원,김규석,김윤범 대한한방안이비인후피부과학회 2020 한방안이비인후피부과학회지 Vol.33 No.3
Objectives : The purpose of this study is to investigate the effect and side effects of steroids on dermatitis and skin barrier through lipid metabolism. And to propose using Herbal medicine to suppress Steroid rebound and prevent side effects. Methods : We reviewed recent studies about the relationship between dermatitis, skin lipid, steroid, and herbal medicine through Google scholar. Results : In various inflammatory skin diseases, the corticosteroid is selected as the primary drug due to its strong anti-inflammatory and immunosuppressive effect. However, long-term use of steroids has a variety of side effects, especially lipid metabolism disruption, which aggravates skin barrier damage underlying various skin diseases and is more susceptible to inflammatory reactions. Conclusions : Herbal medicine is used as a comprehensive approach, and it can be used to reduce the frequency of steroid exposure by protecting against barrier damage by controlling anti-inflammatory, antioxidant, and systemic/sebaceous lipid metabolism and stratum corneum protein differentiation.
한창용(Chang-Young Han),이준석(Joon-Seok Lee),조국환(Kook-Hwan Cho) 한국철도학회 2011 한국철도학회 학술발표대회논문집 Vol.2011 No.10
Recently In Korea region becoming subtropical climate freezing index values have been increasing in winter. The climate condition in Korean became polarized. Since freezing index is increased recently track heaving from frost is often occurred which is ignored in past couple of years. Methods to prevent frost-heaving are circumfusion of calcium chloride and replacement of gravel ballast in usual. The effects of those methods are minimal incontinuous and not eco-friendly. Therefore maintenances are performed repeatedly every year. This study discussed utilizing the waste-tire-chips and insulators in the small structures(bridge and box etc) for prevention of frost-heaving. In order to prove effect of waste-tire-chips laboratory and field tests were conducted with CBR and measurement of frost-heaving amount to prove and verify effect of insulators.
열 플라즈마 인가 전류변화에 의한 ZrVFe 합금 나노분말의 제조특성에 관한 연구
한창석(Chang-Mik Han),정민희(Min-Hee Jung),김헌창(Heon-Chang Kim) 호서대학교 공업기술연구소 2007 공업기술연구 논문집 Vol.26 No.1
Plasma Display Panel (PDP), among various FPD’s, is considered as the most promising candidate for large area display due to its manufacturing process appropriate for a large displaying area, and a good display quality. The getter which can be continuously absorbed and eliminated the generated impurities gas such as O 2 , H 2 , CO, etc. from MgO, barrier rib and fluorescent substances during operation, should be installed in the PDP cell. As a result of install getter in the cell, we could obtain the extending the life time of the PDP with a good display quality. To manufacture getter possessing excellent absorption efficiency, it was produced particles of nano size. In this research, alloy nano powders are synthesized by transferred thermal plasma process which is a promising method to produce composite nano powders of various metals, and also provides high temperature environment(104 K), extremely fast and intense chemical reactions. In this study, the thermal plasma system was operated in a transferred mode and the raw material was used Zr, V ,Fe (57 : 35.8 : 7.2) alloy of ingot type which made from arc melting method, and the produced particles were analyzed according to changing plasma input current range from 120[A] to 160[A] by SEM, EDS, PSA, XRD, BET, PSA (Particle Size Analyzer) and BET analysis of particles synthesized by changing thermal plasma input current. Average size of particles is from 83.2[nm] to 47.8[nm] smaller, in result, we confirmed difference of approximately 35[nm] in diameter of the synthesized particle according to increasing plasma input current because particles was rapidly condensate from difference in temperature of between plasma column area of a high temperature and surround area of plasma column. Result of BET analysis is in inverse proportion to PSA result which has small value of particle diameter by increasing plasma input current. In case of 120[A], BET surface area of particle is 100.9[m2/g],and surface area of particle in condition of 160[A] is 211.2[m2/g]. Thus, as increasing plasma input current, BET surface area of the synthesized particle is more extend.