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하현지,천혜린,박현호 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-
Supramolecular organizing center (SMOC)-mediated signal transduction is an emerging concept in the field of signal transduction that is ushering in a new era. The formation of location-specific, higher-order SMOCs is particularly important for cell death and innate immune signaling processes. Several protein interaction domains, including the death domain (DD) superfamily and the CIDE domain, are representative mediators of SMOC assembly in cell death and innate immune signaling pathways. DD superfamily- and CIDE domain-containing proteins form SMOCs that activate various caspases and provide signaling scaffold platforms. These assemblies can lead to signal transduction and amplification during signaling events. In this review, we summarize recent findings on the molecular basis of DD superfamily- and CIDE domain-mediated SMOC formation.
한국 성인의 단백질 섭취량 추이 및 적절성 평가: 2010 ~ 2019년 국민건강영양조사 자료를 활용하여
함현지,하경호 대한지역사회영양학회 2022 대한지역사회영양학회지 Vol.27 No.1
Objectives: This study aimed to evaluate dietary protein intake and its adequacy among Korean adults during recent 10 years. Methods: Based on the 2010 ~ 2019 Korea National Health and Nutrition Examination Survey (KNHANES) data, a total of 51,296 adults aged 19 years old or more who participated in a one-day 24-hr dietary recall were included. Dietary protein intake was estimated as percentages of total energy (% of energy) and grams per body weight (g/kg/ day) and compared with the 2020 Dietary Reference Intakes for Koreans to evaluate the adequacy of protein intake. In addition, proportions of people whose protein intakes were less than the estimated average requirement (EAR) and above the upper limit of the acceptable macronutrient distribution range (AMDR) (> 20% of energy) were calculated according to sociodemographic characteristics. Results: Protein intake was increased from 14.7% of energy in 2010 to 15.6% of energy in 2019 among Korean adults. However, there was no increase in protein intake relative to the recommended nutrient intake (% RNI) during the recent 10 years. Protein intake relative to the RNI was decreased from 130.2% in 2010 to 121.1% in 2019 (P for trend < 0.0001) among total participants, and a significant decreasing trend was observed in all age groups except for over 65 years old. However, protein intake relative to the RNI was lowest in the elderly (98.6%). Proportions of low protein intake (< EAR) and high protein intake (> AMDR) increased in the past 10 years (P for trend < 0.0001 for all), and these were associated with socioeconomic statuses, such as education and household income levels. Conclusions: These findings suggest that protein adequacy in Korean adults has not been improved over the past decade compared with recommended levels. Nutritional education and intervention programs should consider different intake levels according to sociodemographic characteristics.
류현지,김일석,진상근,송영민,하경희,박기훈 한국축산식품학회 2004 심포지움 및 학술발표회 Vol.- No.34
pH는 숙성기간이 경과함에 따라 고추장소스(T1)와 불고기소스(T2)에서 모두 유의적으로 상승하였으며(P〈0.05), 전단력에서 T1은 전 숙성 기간 동안, T2는 숙성 20일까지는 유의성이 없었으나, 숙성기간이 경과함에 따라 증가하는 경향이었다. 염도와 당도는 저장기간이 경과함에 따라 모두 증가하는 경향이었다. 염도와 당도는 숙성기간에 따라 증가하는 경향이 있으며, T1이 T2보다 전 숙성기간 동안 높게 나타났다.
가교화 β-Cyclodextrin과 식물성 Sterol을 이용한 콜레스테롤 저하 마요네즈의 연구
정태희,하현지,안정좌,곽해수 한국축산식품학회 2008 한국축산식품학회지 Vol.28 No.2
The objective of the present study was to develop cholesterol-reduced and phytosterol-supplemented mayonnaise using crosslinked β-cyclodextrin and examine its physicochemical and sensory attributes during 10 months of storage. The composition of cholesterol-reduced phytosterol-supplemented mayonnaise was similar to the control. The amount of cholesterol removed ranged from 90.67 to 92.47%. The TBA absorbance of the samples showed that the more phytosterol the sample contained, the lower the TBA absorbance value. The viscosity of cholesterol-reduced mayonnaise with 2.0% phytosterol decreased significantly during storage (p