복합고분자용액법에 의한 가시광에 반응하는 TiO₂:Zr, N 광촉매의 제조 및 NO 광분해 특성

최재영,김지영,조영혁,장희동,장한권,김병곤,김태오,Choi, Jae-Young,Kim, Ji-Young,Cho, Young-Hyuek,Jang, Hee-Dong,Chang, Han-Kwon,Kim, Byoung-Gon,Kim, Tae-Oh 한국분말야금학회 2008 한국분말재료학회지 (KPMI) Vol.15 No.1

Visible-light responsive $TiO_2$:Zr, N powders were prepared by polymer complex solution method and the particle properties were characterized by using transmission electron microscope, BET method, X-ray diffractometer and UV-Vis spectrophotometer. The photocatalytic reactivity of the catalysts was also estimated by analyzing NO degradation. Polyhedral $TiO_2$ powder having about 20 um in the average particle diameter was successfully prepared, The XRD analysis revealed that the as-prepared powder consisted of anatase and rutile phases. The light absorption of the as-prepared $TiO_2$:Zr, N powder was shifted to the visible light. In addition, the as-prepared $TiO_2$:Zr, N nanoparticles showed the higher photocatalytic activity than the commercial $TiO_2$ under both UV and visible lights.

제장간막관 및 혈관 잔류이상에 대한 임상적 고찰

최재영,정풍만,Choi, Jae-Young,Jung, Poong-Man 대한소아외과학회 1998 소아외과 Vol.4 No.1

Of 72 patients with vitelline duct and vessel remnants, 45 (62.5 %) had symptomatic lesions. The mean age of the patients was 27.9 months. Males predominated (4.6 : 1). There were 22 cases of Meckel's diverticulum, 6 of Meckel's diverticulum attatched to the umbilicus with a fibrous band, 6 cases of patent vitelline duct, 5 cases of vitelline artery remnants as a fibrous band and 2 cases each of umbilical sinus and polyp, and vitelline cyst. Twenty-three patients (51 %) presented with intestinal obstruction, 6(13 %) with rectal bleeding, 4(9 %) with perforated Meckel's diverticulum, 5 with intestinal juice drainage through umbilicus, 5 with umbilical lesions, 1 with abdominal mass, and 1 with sepsis. Intestinal obstruction due to fibrous band developed during infancy(average age; 4.6 months). Seventeen asymptomatic Meckel's diverticulum, 8 obliterated vitelline artery remnants and 1 vitelline vein remnant as fibrous band, and 1 vitelline cyst were found incidentally at laparotomy. About 82 % of the complicated Meckel's diverticulum presented in infants and children less than 4 years of age.

고지방식이로 유도된 C57BL/6 mice에서 감국이 미치는 비만억제 효과

최재영,이자복,김명옥,Choi, Jae Young,Lee, Ja-bok,Kim, Myeong-ok 중소기업융합학회 2021 융합정보논문지 Vol.11 No.4

감국의 유산균 발효를 통한 감국 배양물(CILL)의 비만억제 식품의 소재로서 가능성을 알아보기 위해 고지방식이로 유도된 C57BL/6 mice에서의 체중, body fat mass, T cell 등을 측정하였다. 체중 변화에서 CILL 군 (25.15±2.44 g)은 4주부터 체중 감소를 보였으며, 1주차부터 8주차까지 낮은 증체량을 유지했다(1.00±0.53 g). 8주 체중(30.38±4.17 g)은 HFD 군(60% high fat diet, 34.99±2.09 g) 대비 13.15%의 체중 감소를 보였다. Fat mass는 10.3022±2.8813 g로 감소했으며, 간 절대 중량에서 HFD 군에 비해 감소하였다. CD4+ T cell 4.84±1.33%, CD8+ T cell 7.02±2.26%, CD4+CD8+ T cell 1.46±0.81%로 HFD 군에 비해 높게 측정되었다. 결과적으로 CILL은 비만억제 효과가 있으며, CILL내의 비만억제 물질을 선별한다면 효과적인 비만억제 식품 소재로서의 가능성이 있을 것으로 사료된다. In order to determine the possibility that Chrysanthemum indicum L. cultured with Lactococcus lactis (CILL) is a material for obesity suppression food, the body weight, body fat mass, and T cells were determined in C57BL/6 mice induced by a high fat diet. The CILL (25.15±2.44 g) demonstrated weight loss from week 4 onward and maintained a low weight gain from week 1 to week 8 (1.00±0.53 g). The 8-week body weight (30.38±4.17 g) indicated loss of 13.15% when compared to the HFD (60% high fat diet, 34.99±2.09 g). Fat mass decreased to 10.3022±2.8813 g, and the absolute liver weight decreased relative to that in the HFD. CD4+ T cells were 4.84±1.33%, CD8+ T cells 7.02±2.26%, and CD4+CD8+ T cells 1.46±0.81%, which were all higher than those in the HFD. As a result, CILL can be used as a material for preventing obesity as an effective measure toward reducing weight when consumed orally.

의사결정나무법을 이용한 설문지의 응답특성에 대한 임상적 검토

최재영,박성식,Choi, Jae-Young,Park, Seong-Sik 사상체질의학회 2003 사상체질의학회지 Vol.15 No.3

Objectives: This paper was for studying the constitutional differences between questionnaire and clinical diagnosis, and to be helpful to make a diagnosis Sasang constitution. Using the result of this study, it will be helpful to diagnose a Sasang constitution. Methods: There were 331 patients(135 men and 196 women) who answered questionnaire and were diagnosed by the Sasang constitution specialist at constitutional clinic of Dongguk Bundang Oriental Hospital. Using the response of questionnaire and several statistical techniques, we tried to find the characteristics of questionnaire response among each constitution and consistency between questionnaire and clinical diagnosis. Results: As a result of the analysis of the consistency between clinical diagnosis and questionnaire, the consistency was low degree(kappa value = 0.320) and Taeumin and Soeumin had more consistency than Soyangin.

산왕거미 (Araneus ventricosus) 혈구의 미세구조

최재영,문명진,Choi, Jae-Young,Moon, Myung-Jin 한국현미경학회 2006 Applied microscopy Vol.36 No.4

산왕거미 (Araneus ventricosus) 혈구의 유형을 세포화학적 및 percoll 밀도구배를 이용한 물리화학적 특성에 따라 구분하고, 각각의 미세구조를 고배율의 전자현미경으로 비교 관찰하였다. 혈구는 세포질에 함유된 과립의 유무에 따라 과립혈구와 무과립혈구로 구분되었으며. 과립혈구는 과립의 특성에 따라 다시 산호성 과립혈구와 염기호성 과립혈구, 그리고 헤모시아닌 과립을 함유한 혈색소혈구의 세 가지 유형으로 세분되었다. 산호성 과립혈구는 전체 혈구유형중 약 5%정도를 차지하였으며, 염기호성 과립혈구는 산호성 과립혈구에 비해 과립의 크기가 크고 구형이었다. 한편 무과립혈구는 혈구중 가장 크기가 작은 투명혈구와 심관의 내강에 주로 분포하는 편도혈구, 그리고 탈피 시에만 출현하는 대형의 탈피혈구로 다시 세분되었다. Hemocytes of the spider Araneus ventricosus were investigated with histochemistry, density analysis of percoll gradient, and fine structural examinations using transmission electron microscope. The hemocytes of this spider were classified into two major groups: granulocytes and non-granulocytes. The granular hemocytes were subdivided into three subtypes according to their histochemical properties which are eosinophilic granuloctes(EGs), basophilic granulocytes(BGs) and cyanocytes. The EGs, which have small granules within the cytoplasm comprise about 5% of the total henocytes. However the granules of BGs are larger than those of HGs. The cyanocytes were characterized to contain hemocyanin granules in their cytoplasm. On the other hand, the non-granulocytes were divided into three subtypes; hyaline leucocytes, oenocytoids, and molting homocytes. The hyaline leucocytes are the most abundant and the smallest hemocyte type in this spider. The oenocytoids that have $10{\sim}15{\mu}m$ in diameter are mostly found at the marginal region of the myocardium in the heart tube. The molting hemocytes, which only appeared during the molting period, contains plenty of glycogen particles in their cytoplasm.

소아 신장이식 환자에서 연령 및 성별에 따른 타크롤리 무스의 약동학적 차이에 관한 단일기관 연구

최재영,장경미,황영주,최봉석,박종광,윤영란,김찬덕,조민현,Choe, Jae Young,Jang, Kyung Mi,Hwang, Young Ju,Choi, Bong Seok,Park, Jong Kwang,Yoon, Young Ran,Kim, Chan Duck,Cho, Min Hyun 대한소아신장학회 2014 Childhood kidney diseases Vol.18 No.1

목적: 소아 신장 이식 환자에서 흔히 사용되는 면역 억제제 타크롤리무스는 성별, 연령별, 인종별로 다양한 약동학적 특성이 있음이 알려져 있다. 본 연구는 우리나라 소아신장 이식 환자가 가지는 타크롤리무스의 약동학적 특징을 파악하고 관련되는 인자를 알아보기 위해 시행되었다. 방법: 경북대병원 소아청소년과에서 신장 이식을 시행받고 초기 면역 억제치료로 타크롤리무스가 사용된 환자 9명을 대상으로, 사용된 약 용량과 혈중 최저 농도 등을 후향적으로 조사하였고 이들의 약동학적 특성을 성인 대조군과 비교하였다. 결과: 남아의 평균 약 용량은 여아에 비해 유의하게 높았으나 혈중 최저 농도는 두 군 간에 유의한 차이가 없었고 청소율 또한 남아에서 유의하게 높았다. 12세 이상의 평균 약 용량은 12세 미만에 비해 낮았고 혈중 최저 농도는 높은 경향을 보였으나 유의한 차이는 없었다. 성인은 12세 이상, 미만 모두의 경우 보다 유의하게 약 용량이 적었으나 혈중 최저 농도에서는 유의한 차이가 없었다. 또한, 청소율와 반감기에서도 모두 유의한 차이를 보였다. 결론: 소아 신장 이식에서 사용되는 타크롤리무스는 나이가 어릴수록, 남아의 경우에 좀 더 많은 용량을 투여해야 할 가능성이 있음을 확인할 수 있었다. 우리나라 소아 신장 이식 환자에서 타크롤리무스의 적절한 치료용량을 확인하기 위해서는 이상의 관련인자에 대한 추가적인 전향적인 연구가 필요하다고 사료 된다. Purpose: The pharmacokinetics of tacrolimus, one of the most widely used immunosuppressive drugs, are known to vary by sex, age, and ethnicity during pediatric transplantation. This study assessed the pharmacokinetic characteristics and associated factors of tacrolimus in Korean children receiving a kidney transplant. Methods: We retrospectively reviewed the pharmacokinetic data (therapeutic dose, trough level, clearance, and half-life) of 9 children who were given tacrolimus as one of their initial immunosuppressive drugs after kidney transplantation. In addition, we compared the findings to data from 10 adult kidney transplant recipients. Results: The mean age of our pediatric patients was 13.9 years, and the maleto- female ratio was 4:5. The mean dose of tacrolimus was $0.19{\pm}0.14$ mg/kg/day. The mean dose of tacrolimus for males was $0.23{\pm}0.12$ mg/kg/day, which was significantly higher than the dose for females ($0.16{\pm}0.14$ mg/kg/day). The trough level was not significantly different between both groups. The clearance rate of tacrolimus for males was also significantly higher than females. Although the dosage of tacrolimus for patients over the age of 12 years was lower ($0.18{\pm}0.13$ vs. $0.21{\pm}0.16$ mg/kg/day) and the trough level was higher ($8.2{\pm}4.5$ vs. $7.2{\pm}4.2$ mg/mL) than that for patients under the age of 12 years, there was no significant difference between them. However, there were significant differences between children and adults in dose, clearance, and half-life of tacrolimus. Conclusion: Out study suggests that the pharmacokinetics of tacrolimus tends to vary with sex and age. Therefore, large-scale prospective studies are required to verify the proper therapeutic dosage of tacrolimus in Korean children.

IT 투자 정당화 요인에 관한 연구

최재영,Choi, Jaeyoung 디지털산업정보학회 2015 디지털산업정보학회논문지 Vol.11 No.4

Although actual business environment is getting difficult and hard, IT companies tend to shy away from of annual investment. Many firms have already reached the 25 percent level. However, the profit and the result of their annual investment needs to be evaluated objectively. IT investment analysis usually proceeds by comparing benefits and costs of an IT investment. Much of the problem derives from the historical treatment of IT as an overhead expense rather than a capital asset. What is most worrying about the current situation is the pressure to take a very short-term view of IT. Therefore, this research aims to analyses and justify the necessity of Visionary IT Investment. For this, it is crucial to identify the factors, which affect positively Visionary IT Investment and understand the role of CIO and explain the result of Visionary IT Investment, which is differed to related business and by different business environment. As a result of this study, the legitimacy of IT Investment is proved through analyzing the business value of not investing and cost-avoidance strategies.

팔로 4징의 완전 교정술 후 장기 추적 관찰상 나타나는 문제 - 만기 관리의 새로운 패러다임 -

최재영,Choi, Jae Young 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.7

악성사이트 검출을 위한 안전진단 스케줄링

최재영,김성기,민병준,Choi, Jae Yeong,Kim, Sung Ki,Min, Byoung Joon 한국정보처리학회 2013 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.2 No.9

Current web has evolved to a mashed-up format according to the change of the implementation and usage patterns. Web services and user experiences have improved, however, security threats are also increased as the web contents that are not yet verified combine together. To mitigate the threats incurred as an adverse effect of the web development, we need to check security on the combined web contents. In this paper, we propose a scheduling method to detect malicious web pages not only inside but also outside through extended links for secure operation of a web site. The scheduling method considers several aspects of each page including connection popularity, suspiciousness, and check elapse time to make a decision on the order for security check on numerous web pages connected with links. We verified the effectiveness of the security check complying with the scheduling method that uses the priority given to each page. 최근의 웹은 구현 방법과 이용 패턴이 변화되면서 서로 연결되고 융합되는 형태로 변화하였다. 서비스가 진화되고 사용자 경험이 향상되었으나 다양한 출처의 검증되지 않은 웹자원들이 서로 결합되어 보안 위협이 가중되었다. 이에 웹 확장의 역기능을 억제하고 안전한 웹서비스를 제공하기 위해 확장된 대상에 대한 안전성 진단이 필요하다. 본 논문에서는 웹사이트의 안전한 운영을 위해 안전진단을 외부 링크까지 확장하여, 진단 대상을 선별하고 지속적으로 진단하여 악성페이지를 탐지하고 웹사이트의 안전성을 확보하기 위한 스케줄링 방안을 제안한다. 진단 대상의 접속 인기도, 악성사이트 의심도, 검사 노후도 등의 특징을 추출하고 이를 통해 진단 순서를 도출하여 순서에 따라 웹페이지를 수집하여 진단한다. 실험을 통해 순차적으로 반복 진단하는 것보다 순위에 따라 진단 주기를 조정하는 것이 중요도에 따라 악성페이지 탐지에 효과적임을 확인하였다.

원격코드검증을 통한 웹컨텐츠의 악성스크립트 탐지

최재영,김성기,이혁준,민병준,Choi, Jae-Yeong,Kim, Sung-Ki,Lee, Hyuk-Jun,Min, Byoung-Joon 한국정보처리학회 2012 정보처리학회논문지 C : 정보통신,정보보안 Vol.19 No.1

Sharing cross-site resources has been adopted by many recent websites in the forms of service-mashup and social network services. In this change, exploitation of the new vulnerabilities increases, which includes inserting malicious codes into the interaction points between clients and services instead of attacking the websites directly. In this paper, we present a system model to identify malicious script codes in the web contents by means of a remote verification while the web contents downloaded from multiple trusted origins are executed in a client's browser space. Our system classifies verification items according to the origin of request based on the information on the service code implementation and stores the verification results into three databases composed of white, gray, and black lists. Through the experimental evaluations, we have confirmed that our system provides clients with increased security by effectively detecting malicious scripts in the mashup web environment. 최근 웹사이트는 매쉬업, 소셜 서비스 등으로 다양한 출처의 리소스를 상호 참조하는 형태로 변화하면서 해킹 시도도 사이트를 직접 공격하기보다 서비스 주체와 연계 서비스, 클라이언트가 상호 작용하는 접점에 악성스크립트를 삽입하는 공격이 증가하고 있다. 본 논문에서는 웹사이트 이용 시 신뢰관계에 있는 여러 출처로부터 다운받은 웹컨텐츠의 HTML 코드와 자바스크립트 코드가 클라이언트 브라우저에서 구동 시 삽입된 악성스크립트를 원격의 검증시스템으로부터 탐지하는 모델을 제안한다. 서비스 주체의 구현코드 정보를 활용하여 요청 출처에 따라 검증 항목을 분류하고 웹컨텐츠의 검증 요소를 추출하여 검증 평가결과를 화이트, 그레이, 블랙 리스트로 데이터베이스에 저장하였다. 실험평가를 통해 제안한 시스템이 악성스크립트를 효율적으로 탐지하여 클라이언트의 보안이 향상됨을 확인하였다.