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만성 신부전 환자에서 Catecholamine 의 제거율
이은주(Eun Joo Lee),위경소(Kyoung So Wee),최태승(Tae Seung Choe),차대룡(Dae Ryong Cha),조원용(Won Yong Cho),김형규(Hyoung Kyu Kim),김형건(Hyoung Gun Kim),최원충(Won Chung Choi) 대한내과학회 1989 대한내과학회지 Vol.37 No.5
N/A The adrenergic system interacts with a vaiety of tissues and organs, including the kidney. However, there is little known about the renal clearance of catecholamine (CAs) in man. To obtain this information, 4 normal subjects and 6 patients with chronic renal failure (CRF) were studied. Plasma and urinary CAs concentrations were measured by high performance liquid chromatography with an electrochemical detector. Plasma CAs concentrations (pg/ml) were norepinephrine (NE) 44.62±83.29 (pg/ml) end DOPAC 585.58±462.47 in normal subjets, and NE 632.20±290.40 and DOPAC 990.55±69.05 in CRF. Plasma CAs concentrations of the CRF group were higher than those of normal subjects, but did not differ significantly among the groups (p<0.05). Urinary CAs excretion amounts were NE 59.3±34.9 (pg/ml), E 11.9±10.2. DOPAC 27.l±61.4, and dopamine 13.4±11.2 in normal subjects, and NE 100.0±90.1, E 135.5±147.4, DOPAC 401.7±500.7, and dopamine 163.9±115, 7 in CRF. Urinary CAs and CAs clearance levels were lower in the CRF group than in normal subjects, but did not differ significantly between the groups. It is concluded that a chronic reduction in excretory kidney function may have no relevant impact on circulatory levels of CA per se, although their urinary excretion falls distinctly at the stage of advanced renal failure. These aspects deserve consideration when pathogenetic or diagnostic studies of catecholamines are performed in normotensive or hypertensive patients with impaired kidney function.
김홍용(Hong Yong Kim),고일향(Il Hyang Ko),이진호(Jin Ho Lee),김관엽(Kwan Yop Kim),류종철(Jong Cheol Ryu),차순주(Soon Joo Cha),신원창(Won Chang Shin),박태준(Tae Joon Park),최원충(Won chung Choi) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4
Carcinoid tumors which arise from enterochromaffin cells are usually found in the appendix, ileun, bronchus and rectum. Carcinoid tumors of the biliary tract are exceedingly rare and pre-operative diagnosis is very difficult. We report a case of carcinoid tumor of the gallbladder in a 43-year-old man presenting jaundice and right upper quadrant abdominal pain as a chief complaint. A tumor of the neck of gallbladder was demonstrated with ultrasonography, computed tomography, endoscopic retrograde cholangiopan-creatography, and percutaneous cholangiography and was confirmed as carcinoid tumor at operation.
경목정맥 간내문맥정맥 단락술(Transjugular Intrahepatic Portosystemic Shunt)로 치료되지 않은 난치성 간성 흉수 1례
박혜원,허웅,김성준,신원창,최원충,이진호 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.3
Refractory hepatic hydrothorax has been treated by conservative methods: salt and water restriction, diuretics, thoracentesis, thoracostomy, and pleurodesis. The results, however, havebeen disappointing. Recently, TIPS has emerged as a new method for refractory hepatic hydrothorax, but it may lead to fatal complications. We report a case of refractory hepatic hydrothorax that was not treated by TIPS despite of successful control of ascitest. (Korean J Hepatol 2002;8:327-330)
하부 위장관 출혈 환자의 입원 경과와 관련이 있는 초기 임상 지표
김성준,신원창,최원충,이진호,김관엽 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.1
■ Objectives The clinical course of lower gastrointestinal bleeding is variable and sometimes, it is difficult to identify the causative disease and predict hospital outcome. We performed this study to know which clinical information available at emergency room was related with hospital course. ■ Methods and materials Forty-eight patients who visited emergency room for lower gastrointestinal bleeding from 1991 to 2000 were retrospectively devided into 2 groups, critical and stable, according to the hospital course, and we compared the clinical parameters of both groups. ■ Results Male sex, malignant disease, liver cirrhosis, premorbid illness score. packed cell transfusion, organ failure index, hemoglobin, hematocrit, albumin, prothrombin time, total bilirubin, and serum sodium showed significant difference between both groups. ■ Conclusions Clinical information from the patients of lower gastrointestinal bleeding at emergency room was related with hospital course, so clinically it may be used as prognostic index.
남영진,황지영,안정수,김현지,김성준,최원충,이진호,김관엽 인제대학교 백병원 2003 仁濟醫學 Vol.24 No.1
Familial adenomatous polyposis is autosomal dominant inherited disease, which is caused by a mutation in adenomatous polyposis coli gene in chromosome 5q21. It is characterized by the progressive development of hundreds to thousands of adenomatous polyps in the large intestine during the 2nd and 3rd decade of life. If polyps are left untreated, they lead 100% to development of colorectal cancer before the age of 36, or in general terms, about 15 years after the onset of symptoms. We experienced one case of familial adenomatous polyposis with colorectal cancer at the age of 20 years and reported with review of literatures.